6 Results for "

L540

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "L540" in MCE Product Catalog:

Cat. No.: HY-147316
CAS No.: 2574474-81-8
Purity:  99.69%
Target:  

STAT TNK1

Research Areas:  

Cancer

TP-5801 is an orally active TNK1 (non-receptor tyrosine kinase) inhibitor (IC50=1.40 nM), and shows anti-tumor activity .
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Cat. No.: HY-147316A
Purity:  99.34%
Target:  

STAT TNK1

Research Areas:  

Cancer

TP-5801 TFA is an orally active TNK1 (non-receptor tyrosine kinase) inhibitor (IC50=1.40 nM), and shows anti-tumor activity .
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Cat. No.: HY-180412
CAS No.: 226072-63-5
Synonyms: BB-3644
Target:  

MMP

Research Areas:  

Cancer

Solimastat (BB-3644) is a potent metalloproteinase (MMP) inhibitor that blocks constitutive and antibody-stimulated CD30 shedding from cell surfaces with an IC50 of 180 nM. Solimastat enhances persistence of anti-CD30 antibody Ki-3 on cells and favors its internalization. Solimastat enhances cytotoxic activity of Ki-3.dgA towards CD30 + L540 cells. Solimastat can be used for the research of CD30 + malignancies .
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Cat. No.: HY-122101
CAS No.: 17392-79-9
Target:  

JAK Apoptosis

Research Areas:  

Cancer

NSC114792 is a selective JAK3 inhibitor. NSC114792 induces apoptosis. NSC114792 decreases the protein expression of p-JAK3 and p-STAT5 .
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Cat. No.: HY-123099
CAS No.: 1255516-86-9
Target:  

JAK

Research Areas:  

Cancer

MS-1020 is a potent and ATP-competitive JAK3 inhibitor. MS-1020 inhibits JAK3/STAT signaling and induces apoptosis. MS-1020 promotes cell death. MS-1020 decreases the expression of tyrosine phosphorylated STAT3 levels. MS-1020 has the potential for the research of cancers harboring aberrant JAK3 signaling .
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Cat. No.: HY-P992404

Target:  

TNF Receptor

Research Areas:  

Cancer

MDX-1401 is a fully human IgG1 (κ isotype) monoclonal antibody against CD30, with a Kd value of 0.83 nmol/L. MDX-1401 induces antibody-dependent cellular cytotoxicity in CD30-expressing cells and inhibits tumor growth in CD30 + lymphoma xenograft models. MDX-1401 can be used in research related to malignant lymphoma and Hodgkin lymphoma .
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