17392-79-9
Chemical Structure
NSC114792
- CAS No.: 17392-79-9
- Formula:C26H32N4O2S
- Molecular Weight:464.62
IUPAC Name: (8S,9S,10R,13S,14S,17S)-10,13-dimethyl-17-(2-(6-thioxo-1,6-dihydro-9H-purin-9-yl)acetyl)-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
InChIKey: UWSZBXUQILDRMN-LADKUVSDSA-N
SMILES: C[C@@]12[C@@H](C(CN3C=NC4=C3N=CNC4=S)=O)CC[C@@]1([H])[C@]5([H])CCC6=CC(CC[C@]6(C)[C@@]5([H])CC2)=O
Biological Activity: NSC114792 is a selective JAK3 inhibitor. NSC114792 induces apoptosis. NSC114792 decreases the protein expression of p-JAK3 and p-STAT5[1].
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NSC114792 | NSC114792 is a selective JAK3 inhibitor. NSC114792 induces apoptosis. NSC114792 decreases the protein expression of p-JAK3 and p-STAT5. | |||||||||||||||||||||
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Keywords