1255516-86-9

MS-1020 Chemical Structure
1255516-86-9

Chemical Structure

MS-1020

  • CAS No.: 1255516-86-9
  • Formula:C21H18N2O3
  • Molecular Weight:346.38

IUPAC Name: 1-hydroxy-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)-2-naphthamide

InChIKey: KHJNISGKGIHTMY-UHFFFAOYSA-N

SMILES: O=C(C1=CC=C2C=CC=CC2=C1O)NCCC3=CNC4=C3C=C(O)C=C4

Biological Activity: MS-1020 is a potent and ATP-competitive JAK3 inhibitor. MS-1020 inhibits JAK3/STAT signaling and induces apoptosis. MS-1020 promotes cell death. MS-1020 decreases the expression of tyrosine phosphorylated STAT3 levels. MS-1020 has the potential for the research of cancers harboring aberrant JAK3 signaling[1].

Cat. No. Product Name Purity Description Pricing
HY-123099 		MS-1020 MS-1020 is a potent and ATP-competitive JAK3 inhibitor. MS-1020 inhibits JAK3/STAT signaling and induces apoptosis. MS-1020 promotes cell death. MS-1020 decreases the expression of tyrosine phosphorylated STAT3 levels. MS-1020 has the potential for the research of cancers harboring aberrant JAK3 signaling.
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