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LNP systems

" in MedChemExpress (MCE) Product Catalog:

25

Inhibitors & Agonists

2

Fluorescent Dye

12

Biochemical Assay Reagents

7

Isotope-Labeled Compounds

13

Oligonucleotides

1

GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W040193
    DSPC
    15+ Cited Publications

    1,2-Distearoyl-sn-glycero-3-PC; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine

    		 Liposome Others
    DSPC (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
    DSPC
  • HY-138170
    ALC-0315
    Maximum Cited Publications
    39 Publications Verification

    		 Liposome SARS-CoV Infection
    ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
    ALC-0315
  • HY-112760
    18:0 mPEG2000 PE sodium
    1 Publications Verification

    DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium

    		 Liposome Others
    18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery .
    18:0 mPEG2000 PE sodium
  • HY-46759
    Genevant CL1

    		Liposome Infection
    Genevant CL1 is an ionizable lipid (pKa = 6.3) suitable for the preparation of lipid nanoparticles (LNPs) for delivering nucleic acid payloads and intramuscular vaccines. Genevant CL1 is a component of lipid nanoparticle delivery systems for mRNA vaccines .
    Genevant CL1
  • HY-W040193S
    DSPC-d70

    1,2-Distearoyl-sn-glycero-3-PC-d70; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70

    		 Isotope-Labeled Compounds Liposome Others
    DSPC-d70 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
    DSPC-d70
  • HY-174497
    eGFP mRNA

    		mRNA Others
    eGFP mRNA expresses green fluorescent protein derived from the jellyfish Aequorea victoria. eGFP is a commonly used direct-detection reporter gene in mammalian cell culture, which produces bright green fluorescence. This product is synthesized without modified nucleosides, with a Cap1 version cap analog at the 5' end and a 100nt PolyA tail at the 3' end. It can be used as a positive reference for IVT (in vitro transcription) or LNP delivery systems.
    eGFP mRNA
  • HY-147332
    TCL053

    		Liposome Neurological Disease
    TCL053 is an ionizable lipid carrier and used to introduce active components, in particular nucleic acids, into cells with excellent efriciency. TCL053, together with DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycoldimyristoyl glycerol), and cholesterol, forms lipid nanoparticle (LNP) which is able to deliver Cas9 mRNA and sgRNA into skeletal muscle .
    TCL053
  • HY-172509
    N-Tetradecyl-pSar25

    		Biochemical Assay Reagents Liposome Others
    N-Tetradecyl-pSar25 (Compound C14-pSar25) is a polysarcosine (pSar) lipid. PSar lipids exhibit maintained or even enhanced LNP transfection efficiency .
    N-Tetradecyl-pSar25
  • HY-W040193S3
    DSPC-d83

    1,2-Distearoyl-sn-glycero-3-PC-d83; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d83

    		 Isotope-Labeled Compounds Liposome Others
    DSPC-d83 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d83) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
    DSPC-d83
  • HY-148363
    Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate

    		Liposome Inflammation/Immunology
    Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate can be used in lipid nanoparticles (LNP) delivery systems for mRNA vaccine delivery .
    Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate
  • HY-159709
    VL-422

    		Liposome Metabolic Disease
    VL-422 is an ionizable cationic lipid. VL-422 delivers CRISPR complementary single-guide RNA (sgRNA) and Cas9 mRNA to enable in vitro and in vivo gene editing. LNPs containing VL-422 loaded with Cas9 mRNA and sgRNA targeting the ANGPTL3 gene induce the deletion of premature stop codons within the ANGPTL3 gene in the liver of cynomolgus monkeys. Loss-of-function of ANGPTL3 leads to decreased levels of LDL, HDL and cholesterol in plasma. The VL-422 delivery system can be used for the research of gene editing strategies targeting lipid metabolism diseases .
    VL-422
  • HY-D2762
    18:1 PE AF 594 triammonium

    		Fluorescent Dye Cancer
    18:1 PE AF 594 triammonium is a fluorescently labeled phospholipid probe. 18:1 PE AF 594 triammonium can be used as a fluorescent tracer for lipid nanoparticles (LNPs). 18:1 PE AF 594 triammonium is promising for research of drug delivery systems .
    18:1 PE AF 594 triammonium
  • HY-W040193GL
    DSPC (GMP Like)

    1,2-Distearoyl-sn-glycero-3-PC (GMP Like); 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (GMP Like)

    		 Liposome Others
    DSPC (GMP Like) (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is DSPC (HY-W040193) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DSPC (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
    DSPC (GMP Like)
  • HY-112756
    PEG2000-DGG

    		Liposome Others
    PEG2000-DGG is a synthetic lipid. PEG2000-DGG can be used in lipid-based nanoparticle (LNP) delivery systems .
    PEG2000-DGG
  • HY-46759A
    Genevant CL1 monohydrochloride

    		Liposome Infection
    Genevant CL1 monohydrochloride is an ionizable lipid (pKa = 6.3) suitable for the preparation of lipid nanoparticles (LNPs) for delivering nucleic acid payloads and intramuscular vaccines. Genevant CL1 monohydrochloride is a component of lipid nanoparticle delivery systems for mRNA vaccines .
    Genevant CL1 monohydrochloride
  • HY-159713
    Lipid R6

    		Liposome Others
    Lipid R6 is a lipid molecule that can be used to synthesize liposomes and is the lipid component in lipid nanoparticle (LNP) systems.
    Lipid R6
  • HY-W040193S5
    DSPC-d9

    1,2-Distearoyl-sn-glycero-3-PC-d9; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d9

    		 Isotope-Labeled Compounds Liposome Others
    DSPC-d9 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d9) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
    DSPC-d9
  • HY-W040193S1
    DSPC-d74

    1,2-Distearoyl-sn-glycero-3-PC-d74; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74

    		 Isotope-Labeled Compounds Liposome Others
    DSPC-d74 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
    DSPC-d74
  • HY-W040193S6
    DSPC-d13

    1,2-Distearoyl-sn-glycero-3-PC-d13; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d13

    		 Isotope-Labeled Compounds Liposome Others
    DSPC-d13 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d13) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
    DSPC-d13
  • HY-W040193S2
    DSPC-d79

    1,2-Distearoyl-sn-glycero-3-PC-d79; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d79

    		 Isotope-Labeled Compounds Liposome Others
    DSPC-d79 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d79) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
    DSPC-d79
  • HY-W040193S4
    DSPC-d4

    1,2-Distearoyl-sn-glycero-3-PC-d4; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d4

    		 Isotope-Labeled Compounds Liposome Others
    DSPC-d4 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d4) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
    DSPC-d4
  • HY-165427
    Lipid 11

    		Liposome Cancer
    Lipid 11 (Compound Lipid 1) is a cationic lipid for nucleic acid delivery. Lipid 11 forms lipid nanoparticles (LNPs) through electrostatic binding with nucleic acids (such as ceDNA). Lipid 11 forms complexes with negatively charged nucleic acids via cationic amine groups, which can be endocytosed by cells to release nucleic acids for activity. Lipid 11 is promising for research of gene therapy drug delivery systems .
    Lipid 11
  • HY-182097A
    DSPE-PEG3400-GNYTCEVTELTREGETIIELK

    		Liposome Inflammation/Immunology
    DSPE-PEG3400-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a peptide mimicking the function of CD47 (GNYTCEVTELSREGKTVIELK). Modifying the surface of LNPs with GNYTCEVTELSREGKTVIELK significantly reduced the recognition and clearance of LNPs by the mononuclear phagocytic system (MPS), and decreased their accumulation in non-target tissues such as the liver and spleen. DSPE-PEG3400-GNYTCEVTELTREGETIIELK can be used for drug delivery .
    DSPE-PEG3400-GNYTCEVTELTREGETIIELK
  • HY-182097
    DSPE-PEG1000-GNYTCEVTELTREGETIIELK

    		Liposome Inflammation/Immunology
    DSPE-PEG1000-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a peptide mimicking the function of CD47 (GNYTCEVTELSREGKTVIELK). Modifying the surface of LNPs with GNYTCEVTELSREGKTVIELK significantly reduced the recognition and clearance of LNPs by the mononuclear phagocytic system (MPS), and decreased their accumulation in non-target tissues such as the liver and spleen. DSPE-PEG1000-GNYTCEVTELTREGETIIELK can be used for drug delivery .
    DSPE-PEG1000-GNYTCEVTELTREGETIIELK
  • HY-182097B
    DSPE-PEG5000-GNYTCEVTELTREGETIIELK

    		Liposome Inflammation/Immunology
    DSPE-PEG5000-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a peptide mimicking the function of CD47 (GNYTCEVTELSREGKTVIELK). Modifying the surface of LNPs with GNYTCEVTELSREGKTVIELK significantly reduced the recognition and clearance of LNPs by the mononuclear phagocytic system (MPS), and decreased their accumulation in non-target tissues such as the liver and spleen. DSPE-PEG5000-GNYTCEVTELTREGETIIELK can be used for drug delivery .
    DSPE-PEG5000-GNYTCEVTELTREGETIIELK

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