29 Results for "

LNP systems

" in MedChemExpress (MCE) Product Catalog:
Products (29)

29 Results for "LNP systems" in MCE Product Catalog:

44
44 Publications Verification
Cat. No.: HY-138170
CAS No.: 2036272-55-4
Purity:  99.81%
ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
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21
21 Cited Publications
Cat. No.: HY-W040193
CAS No.: 816-94-4
Synonyms: 1,2-Distearoyl-sn-glycero-3-PC; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine
DSPC (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
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1
1 Cited Publications
Cat. No.: HY-112760
CAS No.: 247925-28-6
Purity:  ≥98.0%
Synonyms: DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium
18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery .
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Cat. No.: HY-46759
CAS No.: 1450888-71-7
Genevant CL1 is an ionizable lipid (pKa = 6.3) suitable for the preparation of lipid nanoparticles (LNPs) for delivering nucleic acid payloads and intramuscular vaccines. Genevant CL1 is a component of lipid nanoparticle delivery systems for mRNA vaccines .
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Cat. No.: HY-W040193S
CAS No.: 56952-01-3
Synonyms: 1,2-Distearoyl-sn-glycero-3-PC-d70; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70
DSPC-d70 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
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Cat. No.: HY-174497
Target:  

mRNA

Research Areas:  

Others

eGFP mRNA expresses green fluorescent protein derived from the jellyfish Aequorea victoria. eGFP is a commonly used direct-detection reporter gene in mammalian cell culture, which produces bright green fluorescence. This product is synthesized without modified nucleosides, with a Cap1 version cap analog at the 5' end and a 100nt PolyA tail at the 3' end. It can be used as a positive reference for IVT (in vitro transcription) or LNP delivery systems.
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Cat. No.: HY-147332
CAS No.: 2361162-70-9
Purity:  99.92%
TCL053 is an ionizable lipid carrier and used to introduce active components, in particular nucleic acids, into cells with excellent efriciency. TCL053, together with DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycoldimyristoyl glycerol), and cholesterol, forms lipid nanoparticle (LNP) which is able to deliver Cas9 mRNA and sgRNA into skeletal muscle .
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Cat. No.: HY-172509
CAS No.: 120468-71-5
Research Areas:  

Others

N-Tetradecyl-pSar25 (Compound C14-pSar25) is a polysarcosine (pSar) lipid. PSar lipids exhibit maintained or even enhanced LNP transfection efficiency .
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Cat. No.: HY-W040193S3
CAS No.: 326495-40-3
Synonyms: 1,2-Distearoyl-sn-glycero-3-PC-d83; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d83
DSPC-d83 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d83) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
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Cat. No.: HY-148363
CAS No.: 2714482-26-3
Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate can be used in lipid nanoparticles (LNP) delivery systems for mRNA vaccine delivery .
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Cat. No.: HY-159709
CAS No.: 2765519-47-7
Target:  

Liposome

Research Areas:  

Metabolic Disease

VL-422 is an ionizable cationic lipid. VL-422 delivers CRISPR complementary single-guide RNA (sgRNA) and Cas9 mRNA to enable in vitro and in vivo gene editing. LNPs containing VL-422 loaded with Cas9 mRNA and sgRNA targeting the ANGPTL3 gene induce the deletion of premature stop codons within the ANGPTL3 gene in the liver of cynomolgus monkeys. Loss-of-function of ANGPTL3 leads to decreased levels of LDL, HDL and cholesterol in plasma. The VL-422 delivery system can be used for the research of gene editing strategies targeting lipid metabolism diseases .
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Cat. No.: HY-D2762
CAS No.: 2315262-12-3
18:1 PE AF 594 triammonium is a fluorescently labeled phospholipid probe. 18:1 PE AF 594 triammonium can be used as a fluorescent tracer for lipid nanoparticles (LNPs). 18:1 PE AF 594 triammonium is promising for research of drug delivery systems .
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Cat. No.: HY-177916
DSPE-PEG2000-GNYTCEVTELTREGETIIELK is a targeted lipid-polyethylene glycol-peptide conjugate commonly used in nanomedicine delivery systems (such as liposomes or LNP surface modification).
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Cat. No.: HY-W040193GL
CAS No.: 816-94-4
Synonyms: 1,2-Distearoyl-sn-glycero-3-PC (GMP Like); 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (GMP Like)
DSPC (GMP Like) (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is DSPC (HY-W040193) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DSPC (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
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Cat. No.: HY-112756
PEG2000-DGG is a synthetic lipid. PEG2000-DGG can be used in lipid-based nanoparticle (LNP) delivery systems .
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Cat. No.: HY-46759A
Genevant CL1 monohydrochloride is an ionizable lipid (pKa = 6.3) suitable for the preparation of lipid nanoparticles (LNPs) for delivering nucleic acid payloads and intramuscular vaccines. Genevant CL1 monohydrochloride is a component of lipid nanoparticle delivery systems for mRNA vaccines .
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Cat. No.: HY-159713
CAS No.: 3063868-61-8
Target:  

Liposome

Research Areas:  

Others

Lipid R6 is a lipid molecule that can be used to synthesize liposomes and is the lipid component in lipid nanoparticle (LNP) systems.
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Cat. No.: HY-W040193S1
CAS No.: 326495-38-9
Synonyms: 1,2-Distearoyl-sn-glycero-3-PC-d74; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74
DSPC-d74 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
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Cat. No.: HY-W040193S2
CAS No.: 326495-39-0
Synonyms: 1,2-Distearoyl-sn-glycero-3-PC-d79; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d79
DSPC-d79 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d79) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
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Cat. No.: HY-W040193S4
CAS No.: 326495-35-6
Synonyms: 1,2-Distearoyl-sn-glycero-3-PC-d4; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d4
DSPC-d4 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d4) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
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