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  3. N-Tetradecyl-pSar25

N-Tetradecyl-pSar25 (Compound C14-pSar25) is a polysarcosine (pSar) lipid. PSar lipids exhibit maintained or even enhanced LNP transfection efficiency.

For research use only. We do not sell to patients.

N-Tetradecyl-pSar25

N-Tetradecyl-pSar25 Chemical Structure

CAS No. : 120468-71-5

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Based on 1 publication(s) in Google Scholar

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Description

N-Tetradecyl-pSar25 (Compound C14-pSar25) is a polysarcosine (pSar) lipid. PSar lipids exhibit maintained or even enhanced LNP transfection efficiency[1].

In Vitro

PSar lipids exhibit maintained or even enhanced LNP transfection efficiency[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1990.35

Formula

C89H156N26O25

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(NCCCCCCCCCCCCCC)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CNC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (50.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5024 mL 2.5121 mL 5.0242 mL
5 mM 0.1005 mL 0.5024 mL 1.0048 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.5024 mL 2.5121 mL 5.0242 mL 12.5606 mL
5 mM 0.1005 mL 0.5024 mL 1.0048 mL 2.5121 mL
10 mM 0.0502 mL 0.2512 mL 0.5024 mL 1.2561 mL
15 mM 0.0335 mL 0.1675 mL 0.3349 mL 0.8374 mL
20 mM 0.0251 mL 0.1256 mL 0.2512 mL 0.6280 mL
25 mM 0.0201 mL 0.1005 mL 0.2010 mL 0.5024 mL
30 mM 0.0167 mL 0.0837 mL 0.1675 mL 0.4187 mL
40 mM 0.0126 mL 0.0628 mL 0.1256 mL 0.3140 mL
50 mM 0.0100 mL 0.0502 mL 0.1005 mL 0.2512 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
N-Tetradecyl-pSar25
Cat. No.:
HY-172509
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