1 Result for "

MCF-7/PTX cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MCF-7/PTX cells" in MCE Product Catalog:

Cat. No.: HY-163981
Target:  

P-glycoprotein

Research Areas:  

Cancer

ABCB1-IN-2 (compound 16q) is a functional inhibitor that can directly bind to the ABCB1 protein and stabilize its structure without affecting the expression and subcellular localization of ABCB1. ABCB1-IN-2 can increase the sensitivity of MCF-7/ADR cells to paclitaxel (PTX), increase the accumulation of PTX, and prevent the accumulation and excretion of luciferin Rh123 mediated by ABCB1. ABCB1-IN-2, as an ABCB1-mediated multidrug resistance (MDR) reversal agent, shows a strong ability to reverse MDR .
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