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Results for "

MCT-IN-1

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N4115
    Syrosingopine
    Maximum Cited Publications
    13 Publications Verification

    Su 3118

    		 Monocarboxylate Transporter Cardiovascular Disease Cancer
    Syrosingopine (Su 3118) is an orally active lactate transporters (MCT1/MCT4) dual inhibitor, which can reduce glycolysis and induce synthetic lethality in cancer cells when combine with metformin. Syrosingopine shows anti-hypertensive activity by depleting peripheral stores of norepinephrine [1] .
    Syrosingopine
  • HY-150314
    MCT-IN-1

    		Monocarboxylate Transporter Cancer
    MCT-IN-1 (Compound 2) is a potent MCT inhibitor, with IC50 values of 9 nM and 14 nM against MCT1 and MCT4, respectively. MCT-IN-1 can be used in research related to solid tumors [1].
    MCT-IN-1
  • HY-D0067
    7ACC1
    5+ Cited Publications

    DEAC; CoumarIN D 1421; D 1421

    		 Monocarboxylate Transporter Cancer
    7ACC1 (DEAC; Coumarin D 1421; D 1421) is a monocarboxylate transporter 1 (MCT-1)/MCT-4 specifc blocker. 7ACC1 attenuates renal cancer cell proliferation, migration, invasion and down-regulates the levels of MCT1/MCT4 expression and extracellular lactate. 7ACC1 is promising for research of cancers [1] .
    7ACC1
  • HY-75625
    2-Hydroxy-4-methoxybenzoic acid

    4-Methoxysalicylic Acid

    		 Monocarboxylate Transporter Apoptosis Mitochondrial Metabolism Cardiovascular Disease Metabolic Disease Cancer
    2-Hydroxy-4-methoxybenzoic acid is an orally active inhibitor of MCT-1 and MCT-4, as well as a plant biomarker. 2-Hydroxy-4-methoxybenzoic acid can be isolated from roots. 2-Hydroxy-4-methoxybenzoic acid induces Apoptosis and loss of mitochondrial membrane potential. 2-Hydroxy-4-methoxybenzoic acid exhibits anticancer activity against breast cancer. 2-Hydroxy-4-methoxybenzoic acid normalizes lactic acid levels. 2-Hydroxy-4-methoxybenzoic acid neutralizes viper venom and attenuates its lethal, hemorrhagic, coagulant and anticoagulant activities in male albino mice. 2-Hydroxy-4-methoxybenzoic acid possesses antihyperlipidemic, antidiabetic and hepatoprotective activities [1] .
    2-Hydroxy-4-methoxybenzoic acid
  • HY-119996A
    AR-C141990 hydrochloride
    1 Publications Verification

    		 Monocarboxylate Transporter Inflammation/Immunology
    AR-C141990 hydrochloride is a potent lactate transporters (monocarboxylate transporters; MCTs) inhibitor with pKi values of 7.6, 6.6 for MCT-1 and MCT-2, respectively [1]. AR-C141990 hydrochloride has immunosuppressive properties and inhibits graft versus host response .
    AR-C141990 hydrochloride
  • HY-N4115R
    Syrosingopine (Standard)

    Su 3118 (Standard)

    		 Reference Standards Monocarboxylate Transporter Cardiovascular Disease Cancer
    Syrosingopine (Su 3118) is an orally active lactate transporters (MCT1/MCT4) dual inhibitor, which can reduce glycolysis and induce synthetic lethality in cancer cells when combine with metformin. Syrosingopine shows anti-hypertensive activity by depleting peripheral stores of norepinephrine [1] .
    Syrosingopine (Standard)

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