1 Result for "

MEDI4212

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MEDI4212" in MCE Product Catalog:

Cat. No.: HY-P991651

Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

MEDI4212 is a humanized IgG1λ monoclonal antibody inhibitor targeting IgE. MEDI4212 potently inhibits human IgE-mediated functional responses through its receptor FcεRI, such as calcium signaling, β-hexosaminidase release and phagocytosis. MEDI4212 prevents the binding of IgE to CD23 with an IC50 of 8 nM. MEDI4212 can be used severe asthma research .
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