3 Results for "

MH-60 cells

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "MH-60 cells" in MCE Product Catalog:

Cat. No.: HY-N14323
CAS No.: 184877-64-3
Madindoline A is an orally active gp130 antagonist with a KD of 288 μM. Madindoline A inhibits IL-6- and IL-11-induced osteoclastogenesis, suppresses IL-6-stimulated serum amyloid A protein production, inhibits bone resorption and bone loss, and also inhibits IL-6- and IL-11-dependent cell line growth, as well as IL-6-dependent Stat3 tyrosine phosphorylation. Madindoline A is applicable for the research of hormone-dependent postmenopausal osteoporosis .
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Cat. No.: HY-N14325
CAS No.: 184877-65-4
Madindoline B is an IL-6 inhibitor. Madindoline B inhibits IL-6-dependent MH-60 cells and has no inhibitory effect on IL-6-independent MH-60 cells. In the presence of 0.1 U/mL IL-6, it inhibits IL-6-dependent MH-60 cells with an IC50 of 30 μM. Madindoline B has no antimicrobial effect .
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Cat. No.: HY-N14126
CAS No.: 179799-38-3
Chlovalicin is found in the strain of Sporothrix sp. FO-4649. In the presence of 0.2 U/mL IL-6, Chlovalicin inhibits the growth of L6-dependent MH60 cells with lC50 of 7.5 μM. Chlovalicin also inhibits the growth of B16 melanoma cells with lC50 of 38 μM. Chlovalicin also displays inhibitory activity on osteoclastogenesis .
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