1 Result for "

MOXR0916

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "MOXR0916" in MCE Product Catalog:

Cat. No.: HY-P99249
CAS No.: 1638935-72-4
Synonyms: Pogalizumab; MOXR 0916

Research Areas:  

Cancer

Vonlerolizumab (Pogalizumab; MOXR 0916) is a humanized IgG1 monoclonal antibody targeting OX40 (CD134). Pogalizumab partially blocks the interaction between OX40 and its natural ligand OX40L upon binding, thereby activating the NF-κB signaling pathway. Pogalizumab enhances T cell activation and proliferation and has shown antitumor activity in mouse models .
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