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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
Mesalamine
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "Mesalamine" in MCE Product Catalog:
41
41 Cited Publications
Synonyms: Mesalamine; 5-ASA; Mesalazine
Category:
Monophenols Ketones, Aldehydes, Acids Phenols Endogenous metabolite Disease Research Fields Cancer
Target:
Cat. No.: HY-B0667
CAS No.: 80573-04-2
Target:
Research Areas:
Balsalazide is a prodrug of amino salicylic acid that releases mesalamine (HY-15027) in the colon, offering various anti-inflammatory effects in areas of colitis, and it also exerts related anticancer effects by regulating the IL-6/STAT3 pathway .
Cat. No.: HY-B0667A
CAS No.: 150399-21-6
Synonyms: Balsalazide disodium dihydrate
Target:
Research Areas:
Balsalazide sodium hydrate is a prodrug of amino salicylic acid that releases mesalamine (HY-15027) in the colon, offering various anti-inflammatory effects in areas of colitis, and it also exerts related anticancer effects by regulating the IL-6/STAT3 pathway .
Synonyms: Mesalamine-d3; 5-ASA-d3; Mesalazine-d3
Synonyms: Mesalamine (Standard); 5-ASA (Standard); Mesalazine (Standard)
Synonyms: Mesalamine-13C6 hydrochloride; 5-ASA-13C6 hydrochloride; Mesalazine-13C6 hydrochloride
Cat. No.: HY-131265
CAS No.: 887256-40-8
Research Areas:
Mesalamine impurity P is an impurity of Mesalamine (HY-15027). 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB .
Synonyms: Mesalamine-D3 hydrochloride; 5-ASA-D3 hydrochloride; Mesalazine-D3 hydrochloride
Cat. No.: HY-15027S4
Synonyms: 5-ASA-d7; Mesalamie-d7; Mesalazie-d7
Cat. No.: HY-15027S3
Synonyms: Mesalamine-d3 disodium; 5-ASA-d3 disodium; Mesalazine-d3 disodium
Cat. No.: HY-15027S2
CAS No.: 1189709-96-3
Synonyms: Mesalamine-13C6; 5-ASA-13C6; Mesalazine-13C6
Cat. No.: HY-108244
CAS No.: 213594-60-6
Target:
Research Areas:
Balsalazide disodium is a prodrug of amino salicylic acid that releases mesalamine (HY-15027) in the colon, offering various anti-inflammatory effects in areas of colitis, and it also exerts related anticancer effects by regulating the IL-6/STAT3 pathway .
Cat. No.: HY-B0667S
CAS No.: 1246834-21-8
Cat. No.: HY-15026
CAS No.: 915798-75-3
Target:
Research Areas:
ATB-429, a novel H2S-releasing derivative of mesalamine, demonstrates significant anti-nociceptive and anti-inflammatory effects in models of irritable bowel syndrome (IBS). By releasing hydrogen sulfide (H2S), ATB-429 modulates colorectal distension-induced hypersensitivity in both healthy and postcolitic rats. It attenuates abdominal withdrawal responses and suppresses spinal c-Fos mRNA expression, indicating its potential to alleviate pain associated with gastrointestinal inflammation. Moreover, ATB-429 down-regulates colonic cyclooxygenase-2 and interleukin-1β mRNA expression, effects not observed with mesalamine alone. The mechanism involves ATP-sensitive K+ (KATP) channels, as evidenced by reversal of ATB-429's effects with glibenclamide. These findings suggest ATB-429 could offer therapeutic benefits for managing painful intestinal disorders linked to inflammation .
Target:
Research Areas:
Mesalazine impurity 2 is an impurity of Mesalazine (HY-15027). 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB. 5-Aminosalicylic acid can inhibit the activity of osteopontin (OPN).
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
