3 Results for "

Myrislignan

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Myrislignan" in MCE Product Catalog:

1
Myrislignan
Myrislignan
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1 Cited Publications
Cat. No.: HY-N0608
CAS No.: 171485-39-5
Category:  

Monophenols Simple Phenylpropanols Phenols Myristicaceae Phenylpropanoids Plants Myristica fragrans Houtt. Disease Research Fields Inflammation/Immunology

Target:  

NF-κB PI3K Akt Apoptosis Ferroptosis Reactive Oxygen Species (ROS) Autophagy ERK

Myrislignan is a PI3K/AKT/NF-κB inhibitor that can cross the blood-brain barrier. Myrislignan exerts anticancer activity by inducing apoptosis and ferroptosis. Myrislignan inhibits the replication and invasion of Toxoplasma gondii; it induces reactive oxygen species (ROS) imbalance, autophagy, and the death of Toxoplasma gondii tachyzoites. Myrislignan inhibits mitochondrial function and ERK1/2 phosphorylation to improve ovariectomy-induced osteoporosis. Myrislignan can be used in studies related to gastric cancer, glioblastoma, osteoporosis, and toxoplasmosis .
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(Rac)-Myrislignan
(Rac)-Myrislignan
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Cat. No.: HY-N0608A
CAS No.: 41535-95-9
Category:  

Monophenols Phenols Myristicaceae Plants Myristica fragrans Houtt. Disease Research Fields Inflammation/Immunology

Target:  

NF-κB

(Rac)-Myrislignan is the racemate of Myrislignan. Myrislignan, a lignan isolated from Myristica fragrans Houtt, possesses anti-inflammatory activities. Myrislignan attenuates LPS-induced inflammation reaction in murine macrophage cells through inhibition of NF-kB signalling pathway activation .
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Myrislignan-13C,d2
Myrislignan-13C,d2
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Cat. No.: HY-N0608S
Myrislignan-13C,d2 is the 13C, d2 deuterated-labeled Myrislignan (HY-N0608). Myrislignan is a PI3K/AKT/NF-κB inhibitor that can cross the blood-brain barrier. Myrislignan exerts anticancer activity by inducing apoptosis and ferroptosis. Myrislignan inhibits the replication and invasion of Toxoplasma gondii; it induces reactive oxygen species (ROS) imbalance, autophagy, and the death of Toxoplasma gondii tachyzoites. Myrislignan inhibits mitochondrial function and ERK1/2 phosphorylation to improve ovariectomy-induced osteoporosis. Myrislignan can be used in studies related to gastric cancer, glioblastoma, osteoporosis, and toxoplasmosis .
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