20 Results for "

N-(2-Methylbutyryl)glycine-13C2,15N

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "N-(2-Methylbutyryl)glycine-13C2,15N" in MCE Product Catalog:

1
Polymyxin B1
Polymyxin B1
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1 Cited Publications
Cat. No.: HY-A0248A
CAS No.: 4135-11-9
Category:  

Infection Microorganisms Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics

Target:  

Bacterial

Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
1
Astressin 2B
Astressin 2B
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1 Cited Publications
Cat. No.: HY-P1108
CAS No.: 681260-70-8
Target:  

CRFR

Research Areas:  

Neurological Disease Inflammation/Immunology

Astressin 2B is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC50=0.57 nM). Astressin 2B blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .
1
Astressin 2B TFA
Astressin 2B TFA
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1 Cited Publications
Cat. No.: HY-P1108A
Target:  

CRFR

Research Areas:  

Neurological Disease Inflammation/Immunology

Astressin 2B TFA is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC50=0.57 nM). Astressin 2B TFA blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B TFA reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B TFA also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B TFA mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B TFA is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .
Glutathione ethyl ester
Glutathione ethyl ester
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Cat. No.: HY-134124
CAS No.: 92614-59-0
Purity:  95.8%
Target:  

Reactive Oxygen Species (ROS)

Research Areas:  

Metabolic Disease

Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .
Rusfertide
Rusfertide
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Cat. No.: HY-P10272
CAS No.: 1628323-80-7
Synonyms: PTG-300
Target:  

Ferroportin

Research Areas:  

Others

Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .
N-(2-Methylbutyryl)glycine-13C2,15N
N-(2-Methylbutyryl)glycine-13C2,15N
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Cat. No.: HY-W754053
N-(2-Methylbutyryl)glycine- 13C2, 15N is the 13C- and 15N-labeled N-(2-Methylbutyryl)glycine (HY-W141919). N-(2-Methylbutyryl)glycine is a Glycine (HY-Y0966) derivative .
MMP-2/MMP-9 Substrate
MMP-2/MMP-9 Substrate
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Cat. No.: HY-P10143
CAS No.: 99828-55-4
Synonyms: Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt
Target:  

MMP

Research Areas:  

Others

MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties .
Polymyxin B1-d7 TFA
Polymyxin B1-d7 TFA
0 Images
Cat. No.: HY-A0248AS
Category:  

Microorganisms Antibiotics Disease Research Antibacterial Other Antibiotics

Target:  

Isotope-Labeled Compounds Bacterial

Polymyxin B1-d7 TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
Noraramtide
Noraramtide
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Cat. No.: HY-P10563
CAS No.: 2580150-96-3
Synonyms: BHV-1100
Target:  

CD38 IFNAR

Research Areas:  

Cancer

Noraramtide (BHV-1100) is an antibody-recruiting molecule. Noraramtide binds to CD38 and recruits natural killer (NK) cells to mediate antibody-dependent cellular cytotoxicity. Noraramtide enhances the capacity of autologous cytokine-induced memory-like (CIML) NK cells to produce IFNγ and CD107a, thereby improving their cytotoxicity against multiple myeloma cells. Noraramtide can be used in the research of multiple myeloma .
SKF 100398
SKF 100398
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Cat. No.: HY-P3066
CAS No.: 77453-01-1
Synonyms: d(CH2)5Tyr(Et)VAVP
Target:  

Vasopressin Receptor

Research Areas:  

Metabolic Disease

SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .
MAPI
MAPI
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Cat. No.: HY-P10828
CAS No.: 1260620-30-1
Target:  

Virus Protease

Research Areas:  

Infection Inflammation/Immunology

MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension to the active site thiol of SV3CP Cys 139. MAPI is promising for research of noroviruses infection .
PD 145065
PD 145065
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Cat. No.: HY-105183
CAS No.: 153049-49-1
Target:  

Endothelin Receptor

Research Areas:  

Others

PD 145065 is a highly potent but non-selective endothelin receptor antagonist with an IC50 value of 4 nM for the ETA receptor for rabbit renal artery vascular smooth muscle cells .
RPP-(Gly-13C2,15N)-FSPFR TFA
RPP-(Gly-13C2,15N)-FSPFR TFA
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Cat. No.: HY-P0206S1
Target:  

Isotope-Labeled Compounds Bradykinin Receptor Endogenous Metabolite Ser/Thr Protease

Research Areas:  

Cardiovascular Disease Endocrinology

RPP-(Gly-1 13C2, 15N)-FSPFR TFA is 13C- and 15N-labeled Bradykinin (HY-P0206). Bradykinin is an effective endothelium-dependent vasodilator that can lower blood pressure. Bradykinin can induce contraction of bronchial and intestinal non-vascular smooth muscle, increase vascular permeability, and participate in the mechanism of pain .
N-(2-Carbamoyl-ethyl)-Val-Leu-anilide
N-(2-Carbamoyl-ethyl)-Val-Leu-anilide
0 Images
Cat. No.: HY-P4756
CAS No.: 282725-67-1
Target:  

Peptides

Research Areas:  

Others

N-(2-Carbamoyl-ethyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
DHATS(Leu-13C6,15N)PVTIPSAVST(Gly-13C2,15N)HTTPLPVTDT TFA
DHATS(Leu-13C6,15N)PVTIPSAVST(Gly-13C2,15N)HTTPLPVTDT TFA
0 Images
Cat. No.: HY-159193S
Target:  

Isotope-Labeled Compounds

Research Areas:  

Others

DHATS(Leu- 13C6, 15N)PVTIPSAVST(Gly- 13C2, 15N)HTTPLPVTDT (TFA) is the 13C and 15N labeled isotope of DHATS-PVTIPSAVST-HTTPLPVTDT (TFA) .
Certepetide-13C2,15N
Certepetide-13C2,15N
0 Images
Cat. No.: HY-P3448S1
Synonyms: CEND-1-13C2,15N; iRGD-13C2,15N; LSTA1-13C2,15N
Target:  

Isotope-Labeled Compounds Complement System Integrin

Research Areas:  

Cancer

Certepetide- 13C2, 15N (CEND-1- 13C2, 15N) is the 13C- and 15N-labeled Certepetide (HY-P3448). Certepetide (CEND-1) is a bifunctional cyclic peptide (a.k.a. iRGD). Certepetide is a tumor-penetrating enhancer via RGD motif interaction with alphav-integrins and via activating NRP-1, and transforms the solid tumor microenvironment into a temporary agent conduit. Certepetide accumulates in tumors, and is used in the research of pancreatic cancer and other solid tumors .
Ro 23-7014
Ro 23-7014
0 Images
Cat. No.: HY-P2592
CAS No.: 113714-78-6
Target:  

Cholecystokinin Receptor

Research Areas:  

Others

Ro 23-7014 is an appetite suppressant. Ro 23-7014 is an analog of cholecystokinin (CCK-7) .
Kahalalide A
Kahalalide A
0 Images
Cat. No.: HY-125628
CAS No.: 179733-11-0
Target:  

Endogenous Metabolite

Research Areas:  

Infection

Kahalalide A is an anti-mycobacterial compound with antimicrobial activity. Kahalalide A is derived from the marine mollusk Elysia rufescens. Kahalalide A has attracted extensive attention in natural product research due to its potential medicinal value .
LLIYFASQSISGIPDR-13C2,15N
LLIYFASQSISGIPDR-13C2,15N
0 Images
Cat. No.: HY-P11344S
Target:  

Isotope-Labeled Compounds

Research Areas:  

Others

LLIYFASQSISGIPDR- 13C2, 15N is the 13C- and 15N-labeled LLIYFASQSISGIPDR.
Polymyxin B1-D-Leu-d7 TFA
Polymyxin B1-D-Leu-d7 TFA
0 Images
Cat. No.: HY-A0248AS1
Category:  

Microorganisms Antibiotics Disease Research Antibacterial Other Antibiotics

Target:  

Isotope-Labeled Compounds Bacterial

Polymyxin B1-D-Leu-d7 TFA is the deuterium labeled Polymyxin B1 (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
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