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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
NOS enzymes
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "NOS enzymes" in MCE Product Catalog:
3
3 Cited Publications
Synonyms: (Rac)-Sapropterin
Category:
Alkaloids Other Alkaloids Disease markers Endogenous metabolite Disease Research Fields Inflammation/Immunology Cardiovascular System Disorder
Target:
Synonyms: Nω-nitro-L-arginine; L-NOARG; L-NG-Nitroarginine
Target:
Research Areas:
NG-nitro-L-arginine (Nω-nitro-L-arginine; L-NOARG; L-NG-Nitroarginine) is a nitric oxide synthase (NO Synthase) inhibitor, with a Kd of 15 nM for constitutive NOS from bovine brain and a Ki of 4.4 μM for inducible NOS from mouse macrophages. NG-nitro-L-arginine competitively blocks the synthesis of NO from L-arginine; in addition, it inhibits endothelium-dependent vasodilation, and exhibits effects such as blood pressure elevation, heart rate reduction and vasoconstriction. NG-nitro-L-arginine regulates mitochondrial respiratory efficiency, antioxidant enzyme activity, lipid peroxidation level and tissue lead content in rats. NG-nitro-L-arginine can be used in studies related to cardiovascular diseases .
Cat. No.: HY-W071685
CAS No.: 945-43-7
Target:
Research Areas:
6, 7-dimethyl-5,6,7, 8-Tetrahydropterin hydrochloride is a synthetic analogue of tetrahydro-L-bioterin and is used as a cofactor required for the NOS isoforms, phenylalanine, tyrosine and tryptophan hydroxylases, and other enzymes .
Cat. No.: HY-135451
CAS No.: 268725-86-6
Target:
Research Areas:
CFM 1571 is a soluble guanylyl cyclase (sGC) activator with an IC50 of ~5.5 μM. CFM 1571 activates sGC in a NO-independent manner and exerts a synergistic effect with NO. CFM 1571 inhibits platelet aggregation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
