6,7-Dimethyl-5,6,7,8-tetrahydropterin hydrochloride
6, 7-dimethyl-5,6,7, 8-Tetrahydropterin hydrochloride is a synthetic analogue of tetrahydro-L-bioterin and is used as a cofactor required for the NOS isoforms, phenylalanine, tyrosine and tryptophan hydroxylases, and other enzymes.
For research use only. We do not sell to patients.
- Purity : 99.62%
- CAS No.: 945-43-7
- Formula: C8H14ClN5O
- Molecular Weight:231.68
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Endogenous Metabolite Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 945-43-7
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Appearance Solid
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Molecular Weight 231.68
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Formula C8H14ClN5O
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Color White to off-white
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SMILES
O=C1N=C(NC2=C1NC(C)C(C)N2)N.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (614 KB)
- English - EN (614 KB)
- Français - FR (614 KB)
- Deutsch - DE (614 KB)
- Norwegian - NO (614 KB)
- Español - ES (614 KB)
- Swedish - SV (614 KB)
- Italian - IT (614 KB)
- Korean - KR (614 KB)
- Portuguese - PT (614 KB)
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Handling Instructions (2659 KB)
References
[1]. Mayer B, et al. In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxide. Naunyn Schmiedebergs Arch Pharmacol. 1995 May;351(5):453-63. [Content Brief]
[2]. Suckling CJ, et al. 6-Acetyl-7,7-dimethyl-5,6,7,8-tetrahydropterin is an activator of nitric oxide synthases. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1563-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)