2. GPCR/G Protein Immunology/Inflammation
  3. Guanylate Cyclase NO Synthase
  4. CFM 1571

CFM 1571 is a soluble guanylyl cyclase (sGC) activator with an IC50 of ~5.5 μM. CFM 1571 activates sGC in a NO-independent manner and exerts a synergistic effect with NO. CFM 1571 inhibits platelet aggregation.

For research use only. We do not sell to patients.

CFM 1571

CFM 1571 Chemical Structure

CAS No. : 268725-86-6

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CFM 1571 Related Antibodies

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Description

CFM 1571 is a soluble guanylyl cyclase (sGC) activator with an IC50 of ~5.5 μM. CFM 1571 activates sGC in a NO-independent manner and exerts a synergistic effect with NO. CFM 1571 inhibits platelet aggregation[1][2].

In Vitro

CFM 1571 is a haem-dependent sGC stimulator that weakly activates purified sGC alone, strongly synergizes with NO, inhibits collagen-induced washed platelet aggregation with an IC50 of 2.8 μM, and has ~12% bioavailability[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CFM 1571 Related Antibodies
Molecular Weight

408.49

Formula

C23H28N4O3
CAS No.
SMILES

O=C(C1=CC(OCCCN(C)C)=NN1CC2=CC=CC=C2)NC3=CC=C(C=C3)OC
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CFM 1571 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CFM 1571268725-86-6CFM1571CFM-1571Guanylate CyclaseNO SynthaseNitric oxide synthasesNOSnitric oxide synthase enzymesPDEscollagen-induced washed human platelet aggregationplatelet aggregation inhibitorhuman sGCsoluble guanylate cyclasephosphodiesterasesNOS enzymescAMP/PKA signalsNOInhibitorinhibitorinhibit

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