4 Results for "

NUGC3 Cells

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "NUGC3 Cells" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-120373
CAS No.: 2230044-57-0
Purity:  98.76%
Target:  

MDM-2/p53

Research Areas:  

Cancer

MB710, an aminobenzothiazole derivative, is a stabilizer of oncogenic p53 mutation Y220C. MB710 binds tightly to the Y220C pocket and stabilizes p53-Y220C, with a Kd of 4.1 μM. MB710 shows anticancer activity in p53-Y220C cell lines .
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Cat. No.: HY-175318S
CAS No.: 3069395-29-2
p53 Activator 15 is an orally active p53 Y220C activator. p53 Activator 15 enhances the DNA binding of p53 Y220C (SC50 = 0.58 nM) and significantly inhibits NUGC-3 cell proliferation. p53 Activator 15 effectively inhibits tumor growth in NUGC-3 xenograft mouse and rat models. p53 Activator 15 can be used to study gastric cancer .
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Cat. No.: HY-160450
CAS No.: 2850211-42-4
Target:  

MDM-2/p53

Research Areas:  

Cancer

p53 Activator 11 (compound A-1) is a potent p53 activator with an EC50 value of 0.478 µM for p53 (Y220C). p53 Activator 11 has the potential for the research of cancer .
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Cat. No.: HY-N17973
CAS No.: 6879-55-6
(-)-Folicanthine is a dimeric tryptamine-related alkaloid found in the fruits of Chimonanthus praecox. (-)-Folicanthine shows cytotoxic against cancer cells. (-)-Folicanthine can be used for the research of cancer, such as gastric carcinoma and hepatocarcinoma .
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