2230044-57-0
2230044-57-0
Chemical Structure
MB710
- CAS No.: 2230044-57-0
- Formula:C16H16IN3O3S
- Molecular Weight:457.29
IUPAC Name: 2-(diethylamino)-5-hydroxy-6-iodo-7-(1H-pyrrol-1-yl)benzo[d]thiazole-4-carboxylic acid
InChIKey: SEBJATZOIHUGAU-UHFFFAOYSA-N
SMILES: O=C(C1=C2N=C(N(CC)CC)SC2=C(N3C=CC=C3)C(I)=C1O)O
Biological Activity: MB710, an aminobenzothiazole derivative, is a stabilizer of oncogenic p53 mutation Y220C. MB710 binds tightly to the Y220C pocket and stabilizes p53-Y220C, with a Kd of 4.1 μM. MB710 shows anticancer activity in p53-Y220C cell lines[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MB710 | 98.81% | MB710, an aminobenzothiazole derivative, is a stabilizer of oncogenic p53 mutation Y220C. MB710 binds tightly to the Y220C pocket and stabilizes p53-Y220C, with a Kd of 4.1 μM. MB710 shows anticancer activity in p53-Y220C cell lines. | ||||||||||||||||||||
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References
Keywords
