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Cat. No.: HY-160450

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p53 Activator 11

p53 Activator 11 (compound A-1) is a potent p53 activator with an EC₅₀ value of 0.478 µM for p53 (Y220C). p53 Activator 11 has the potential for the research of cancer.

For research use only. We do not sell to patients.

CAS No.: 2850211-42-4
Formula: C₂₆H₂₉N₇O₂S
Molecular Weight:503.62

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

p53 Activator 11 Chemical Structure

CAS No.: 2850211-42-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

p53 Activator 11 (compound A-1) is a potent p53 activator with an EC₅₀ value of 0.478 µM for p53 (Y220C). p53 Activator 11 has the potential for the research of cancer^[1].

Chemical Information

CAS No. 2850211-42-4
Molecular Weight 503.62
Formula C₂₆H₂₉N₇O₂S
SMILES

O=S(N)(C1=CC=C(NCC#CC2=C(N3C=CC=C3)N4C=CC=C(NC5CCN(CC5)C)C4=N2)C=C1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sujing LI, et al. Compounds targeting y220c mutant of p53. WO2022213975A1.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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