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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
P450 2B6
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "P450 2B6" in MCE Product Catalog:
36
36 Cited Publications
Cat. No.: HY-17356
CAS No.: 49562-28-9
Target:
Research Areas:
Fenofibrate is a selective PPARα agonist with an EC50 of 30 μM. Fenofibrate also inhibits human cytochrome P450 isoforms, with IC50s of 0.2, 0.7, 9.7, 4.8 and 142.1 μM for CYP2C19, CYP2B6, CYP2C9, CYP2C8, and CYP3A4, respectively.
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1 Cited Publications
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LKY-047, a Decursin derivative, is a potent and selective reversible competitive cytochrome P45022J2 (CYP2J2) inhibitor with an IC50 of 1.7 μM. LKY-047 is inactive against other human P450s, such as CYPs 1A2, 2A6, 2B6, 2C8, 2C9, 2C19, 2D6, 2E1, and 3A .
Category:
Other Monoterpenes Terpenoids Other Diseases Plants Umbelliferae Vernonia Schreb. Disease Research Fields
Target:
Cat. No.: HY-17356S
CAS No.: 1092484-56-4
Cat. No.: HY-17356R
CAS No.: 49562-28-9
Research Areas:
Fenofibrate (Standard) is the analytical standard of Fenofibrate. This product is intended for research and analytical applications. Fenofibrate is a selective PPARα agonist with an EC50 of 30 μM. Fenofibrate also inhibits human cytochrome P450 isoforms, with IC50s of 0.2, 0.7, 9.7, 4.8 and 142.1 μM for CYP2C19, CYP2B6, CYP2C9, CYP2C8, and CYP3A4, respectively.
Cat. No.: HY-W587878
CAS No.: 470-40-6
Thujopsene is the inhibitor for cytochrome P450, that inhibits CYP2B6, CYP3A4, CYP2C19, CYP2C8, CYP2C9 with IC50s of 1.3, 12.6, 13.6, 29.8, and 44.9 μM, respectively. Thujopsene binds to PKM2, inhibits the metabolism pathway of cancer cell, induces apoptosis in MKN45, thereby exhibiting antitumor efficacy. Thujopsene exhibits anti-termite and antifungal activities through autoxidation .
Cat. No.: HY-W099758
CAS No.: 105-21-5
Synonyms: γ-Oenantholacton
Cat. No.: HY-17356G
CAS No.: 49562-28-9
Cat. No.: HY-E72096
Target:
Research Areas:
Human CYP2B6, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, consisting of human cytochrome P450 2B6, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP2B6 is a human cytochrome P450 subtype belonging to the CYP2 family, and also serves as a minor but highly polymorphic hepatic metabolic enzyme that metabolizes various prodrugs or xenobiotics .
Cat. No.: HY-17356S1
CAS No.: 1092484-57-5
Cat. No.: HY-17356S2
CAS No.: 1261395-55-4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
