1954681-29-8
1954681-29-8
Chemical Structure
LKY-047
- CAS No.: 1954681-29-8
- Formula:C23H19NO7
- Molecular Weight:421.40
IUPAC Name: (S)-8,8-dimethyl-2-oxo-7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-7-yl (E)-3-(4-nitrophenyl)acrylate
InChIKey: AEVGNLMZEXKNKR-MRSBXDGLSA-N
SMILES: O=C(O[C@H]1CC(C=C(C=CC(O2)=O)C2=C3)=C3OC1(C)C)/C=C/C4=CC=C([N+]([O-])=O)C=C4
Biological Activity: LKY-047, a Decursin derivative, is a potent and selective reversible competitive cytochrome P45022J2 (CYP2J2) inhibitor with an IC50 of 1.7 μM. LKY-047 is inactive against other human P450s, such as CYPs 1A2, 2A6, 2B6, 2C8, 2C9, 2C19, 2D6, 2E1, and 3A[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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LKY-047 | 99.94% | LKY-047, a Decursin derivative, is a potent and selective reversible competitive cytochrome P45022J2 (CYP2J2) inhibitor with an IC50 of 1.7 μM. LKY-047 is inactive against other human P450s, such as CYPs 1A2, 2A6, 2B6, 2C8, 2C9, 2C19, 2D6, 2E1, and 3A. | ||||||||||||||||||||
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References
Keywords
