Search Result
Results for "
PEG compound
" in MedChemExpress (MCE) Product Catalog:
293
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-Y0873P
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- HY-148865
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Biochemical Assay Reagents
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Others
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Puromycin-bis (PEG2-amide)-Biotin (Compound 3P) is a binding molecule. Puromycin-bis (PEG2-amide)-Biotin binds to ribosome-RNA complexes within single cells. Puromycin-bis (PEG2-amide)-Biotin is used for single-cell translatome sequencing .
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- HY-177203
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Liposome
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Cardiovascular Disease
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DSPE-PEG2000-APWHLSSQYSRT is a PEG compound which composed of DSPE and 12-amino acid cardiac targeting peptide (APWHLSSQYSRT). DSPE-PEG2000-APWHLSSQYSRT can be used for drug delivery .
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- HY-172277A
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Liposome
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Neurological Disease
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DSPE-PEG2000-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG2000-R9 can be used for drug delivery .
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- HY-172354
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Biochemical Assay Reagents
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Others
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Acrylate-PEG2000-NHS is a photosensitive PEG compound that can be cross-linked when exposed to ultraviolet light and is used to synthesize PEG hydrogels .
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- HY-174926A
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- HY-153672
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ADC Linker
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Cancer
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Amine-PEG3-Lys(PEG3-N3)-PEG3-N3 (compound 5) is a branched linker that can be used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-172279
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Liposome
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Infection
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DSPE-PEG1000-TAT is a PEG compound which composed of DSPE and a cell-penetrating peptide (TAT) (HY-P0281). DSPE-PEG1000-TAT can be used for drug delivery .
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- HY-172279C
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Liposome
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Infection
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DSPE-PEG3400-TAT is a PEG compound which composed of DSPE and a cell-penetrating peptide (TAT) (HY-P0281). DSPE-PEG3400-TAT can be used for drug delivery .
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- HY-172354A
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Biochemical Assay Reagents
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Others
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Acrylate-PEG3500-NHS is a photosensitive PEG compound that can be cross-linked when exposed to ultraviolet light and is used to synthesize PEG hydrogels .
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- HY-168940H
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- HY-148484
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Drug Derivative
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Others
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Pomalidomide-5'-PEG5-C2-COOH is an active compound. Pomalidomide-5'-PEG5-C2-COOH can be used for the research of various biochemical .
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- HY-129622
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PROTAC Linkers
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Cancer
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NH2-PEG5-C6-Cl (K-7) is a linker which refers to the PEG composition. NH2-PEG5-C6-Cl can be used in the synthesis of a series of compounds that induce degradation of intracellular molecules by autophagy .
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- HY-172687
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Liposome
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Cardiovascular Disease
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DSPE-PEG2000-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). DSPE-PEG2000-CSTSMLKAC can be used for drug delivery DSPE-PEG2000-CSTSMLKAC enables targeted delivery of associated nanoliposomes to ischemic myocardial cells .
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- HY-156379
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- HY-148896
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- HY-148549
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- HY-168940D
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- HY-172278A
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Liposome
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Cancer
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DSPE-PEG2000-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG2000-CGKRK can be used for drug delivery .
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- HY-130500
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PROTAC Linkers
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Cancer
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Br-PEG3-CH2COOH (compound 28) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-W1048533H
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Biotin-PEG1000-Thiol
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Biochemical Assay Reagents
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Others
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Biotin-PEG1000-SH (Biotin-PEG1000-Thiol) is a biotin PEG polymer containing a thiol (-SH). Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
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- HY-160981
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ADC Linker
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Cancer
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Mal-PEG4-VCP-NB (Compound 17) is a degradable ADC linker containing a maleimide group, 4 PEG units and VCP NB .
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- HY-172279B
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Liposome
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Infection
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DSPE-PEG5000-TAT is a PEG compound which composed of DSPE and a cell-penetrating peptide (TAT) (HY-P0281). DSPE-PEG5000-TAT can be used for drug delivery .
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- HY-172276A
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Liposome
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Cancer
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DSPE-PEG2000-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG2000-R8 can be used for drug delivery .
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- HY-W1048669B
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Biochemical Assay Reagents
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Others
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Biotin-PEG10000-DMG is a compound composed of biotin, PEG, and myristoyl-sn-glycerol, used for drug delivery. Biotin forms a stable non-covalent bond with streptavidin.
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- HY-116027A
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Biotin-PEG10-COOH
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Biochemical Assay Reagents
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Others
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Biotin-PEG10-acid (Biotin-PEG10-COOH) is a biotin-PEG compound containing a carboxyl group (-COOH) that can be used to react with an amine group (NH2) to form a stable amide bond. Biotin-PEG10-acid can be used for protein labeling and drug delivery research .
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- HY-147205E
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Fluorescent Dye
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Others
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Biotin-PEG20000-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138752A
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PROTAC Linkers
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Cancer
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S-acetyl-PEG4-amine (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138752
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PROTAC Linkers
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Cancer
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S-acetyl-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-172354B
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Biochemical Assay Reagents
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Others
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Acrylate-PEG5000-NHS is a photosensitive PEG compound that can be cross-linked when exposed to ultraviolet light and is used to synthesize PEG hydrogels .
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- HY-168940I
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- HY-172274A
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Liposome
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Cancer
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DSPE-PEG2000-APRPG is a PEG compound which composed of DSPE and a APRPG peptide. DSPE-PEG2000-APRPG can be used for drug delivery .
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- HY-W580021
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- HY-172278C
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Liposome
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Cancer
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DSPE-PEG3400-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG3400-CGKRK can be used for drug delivery .
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- HY-172278B
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Liposome
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Cancer
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DSPE-PEG5000-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG5000-CGKRK can be used for drug delivery .
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- HY-172278
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Liposome
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Cancer
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DSPE-PEG1000-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG1000-CGKRK can be used for drug delivery .
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- HY-172681
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Liposome
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Inflammation/Immunology
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DSPE-PEG2000-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG2000-VIP can be used for drug delivery .
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- HY-172682
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Liposome
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Inflammation/Immunology
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DSPE-PEG5000-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG5000-VIP can be used for drug delivery .
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- HY-172681A
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Liposome
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Inflammation/Immunology
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DSPE-PEG3400-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG3400-VIP can be used for drug delivery .
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- HY-W800685
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- HY-W190939
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Biochemical Assay Reagents
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Others
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C11-PEG9-alcohol is a linker with an aliphatic carbon chain and a PEG chain. The hydrophilic PEG chain increases the water solubility of the compounds in the aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
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- HY-W1048533C
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Biotin-PEG5000-Thiol
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Biochemical Assay Reagents
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Others
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Biotin-PEG5000-SH (Biotin-PEG5000-Thiol) is a biotin PEG polymer containing a thiol (-SH). Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
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- HY-W1048533A
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Biotin-PEG2000-Thiol,
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Biochemical Assay Reagents
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Others
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Biotin-PEG2000-SH (Biotin-PEG2000-Thiol) is a biotin PEG polymer containing a thiol (-SH). Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
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- HY-W1048533E
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Biotin-PEG20000-Thiol
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Biochemical Assay Reagents
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Others
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Biotin-PEG20000-SH (Biotin-PEG20000-Thiol) is a biotin PEG polymer containing a thiol (-SH). Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
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- HY-172276C
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Liposome
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Cancer
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DSPE-PEG3400-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG3400-R8 can be used for drug delivery .
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- HY-172276B
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Liposome
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Cancer
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DSPE-PEG5000-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG5000-R8 can be used for drug delivery .
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- HY-172482A
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Liposome
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Cancer
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DSPE-PEG3400-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG3400-TAASGVRSMH can be used for drug delivery .
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- HY-172277B
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Liposome
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Neurological Disease
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DSPE-PEG5000-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG5000-R9 can be used for drug delivery .
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- HY-172687A
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Liposome
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Cardiovascular Disease
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DSPE-PEG3400-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). CSTSMLKAC is capable of mediating selective homing of phage to ischemic heart tissue. DSPE-PEG3400-CSTSMLKAC can be used for drug delivery .
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- HY-172726
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Liposome
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Cancer
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DSPE-PEG2000-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG2000-EB1 can be used for drug delivery .
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- HY-172726A
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Liposome
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Cancer
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DSPE-PEG3400-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG3400-EB1 can be used for drug delivery .
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- HY-172688
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Liposome
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Cardiovascular Disease
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DSPE-PEG5000-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). CSTSMLKAC is capable of mediating selective homing of phage to ischemic heart tissue. DSPE-PEG5000-CSTSMLKAC can be used for drug delivery .
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- HY-172277C
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Liposome
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Neurological Disease
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DSPE-PEG3400-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG3400-R9 can be used for drug delivery .
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- HY-172277
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Liposome
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Neurological Disease
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DSPE-PEG1000-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG1000-R9 can be used for drug delivery .
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- HY-177019
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E3 Ligase Ligand-Linker Conjugates
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Others
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(S,R,S)-AHPC-PEG3-ADIBO-adipic acid (Compound 2a) is a PROTAC ligand (Compound 1d)-linker conjugate. (S,R,S)-AHPC-PEG3-ADIBO-adipic acid can be coupled with aptamer to construct PROTAC .
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- HY-156384
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- HY-W190865
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Biotin-PEG5-COOH
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Biochemical Assay Reagents
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Others
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Biotin-PEG5-acid (Biotin-PEG5-COOH) is a biotin-PEG compound containing a carboxyl group (-COOH) that can be used to react with an amine group (NH2) to form a stable amide bond. Biotin-PEG5-acid can be used for protein labeling and drug delivery research .
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- HY-116027B
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Biotin-PEG11-COOH
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Biochemical Assay Reagents
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Others
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Biotin-PEG11-acid (Biotin-PEG11-COOH) is a biotin-PEG compound containing a carboxyl group (-COOH) that can be used to react with an amine group (NH2) to form a stable amide bond. Biotin-PEG11-acid can be used for protein labeling and drug delivery research .
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- HY-D1312
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Biochemical Assay Reagents
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Others
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Pyrene azide 2 is a compound derived from pyreneacetic acid, connecting a fluorescent pyrene molecule by a PEG2 linker. The PEG units improve the water solubility of the compound.
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- HY-174926
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- HY-174926B
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- HY-172274
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Liposome
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Cancer
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DSPE-PEG1000-APRPG is a PEG compound which composed of DSPE and a APRPG peptide. DSPE-PEG1000-APRPG can be used for drug delivery .
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- HY-172274B
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Liposome
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Cancer
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DSPE-PEG5000-APRPG is a PEG compound which composed of DSPE and a APRPG peptide. DSPE-PEG5000-APRPG can be used for drug delivery .
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- HY-W574509
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Biochemical Assay Reagents
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Cancer
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Tos-PEG2-acid (compound 30) is a PEG linker containing a tosyl group and a terminal carboxylic acid. Tos-PEG2-acid can react with primary amine groups .
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- HY-172680
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Liposome
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Inflammation/Immunology
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DSPE-PEG1000-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG1000-VIP can be used for drug delivery .
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- HY-174937
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DNP-PEG3-COOH
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Biochemical Assay Reagents
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Others
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DNP-PEG3-acid (DNP-PEG3-COOH) is a compound composed of 2,4-dinitroaniline (DNP), three PEG units, and propionic acid, which can be used for drug delivery.
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- HY-W800616
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Biochemical Assay Reagents
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Others
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C11-PEG4-alcohol is a linker with an aliphatic carbon chain and a PEG chain. The hydrophilic PEG chain increases the water solubility of the compounds in the aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
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- HY-174936
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DNP-PEG8-acid
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Biochemical Assay Reagents
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Others
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DNP-PEG8-COOH (DNP-PEG8-acid) is a compound composed of 2,4-dinitroaniline (DNP), three PEG units, and a carboxyl group (-COOH) that can be used for drug delivery.
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- HY-181183
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ADC Linker
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Cancer
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Propargyl-PEG24-acid (Compound 88) is an ADC linker, belonging to the PEG category, and can be used for the synthesis of antibody-drug conjugates (ADCs) .
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- HY-W190933
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Biochemical Assay Reagents
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Others
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Bis-PEG6-TFP ester is a PEG linker with two terminal TFP ester moieties. TFP esters are amine reactive and are also more stable than NHS esters against hydrolysis. The PEG chain increases the water solubility properties of compounds in aqueous media. The water solubility properties of PEG chains are enhanced as the PEG chain grows.
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- HY-W1048533D
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Biotin-PEG10000-Thiol
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Biochemical Assay Reagents
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Others
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Biotin-PEG10000-SH (Biotin-PEG10000-Thiol) is a biotin PEG polymer containing a thiol (-SH). Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
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- HY-W1048533I
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Biotin-PEG3400-Thiol
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Biochemical Assay Reagents
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Others
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Biotin-PEG3400-SH (Biotin-PEG3400-Thiol) is a biotin PEG polymer containing a thiol (-SH). Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
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- HY-W1048533J
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Biotin-PEG40000-Thiol
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Biochemical Assay Reagents
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Others
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Biotin-PEG40000-SH (Biotin-PEG40000-Thiol) is a biotin PEG polymer containing a thiol (-SH). Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
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- HY-W1051916C
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Biochemical Assay Reagents
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Others
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NH2-PEG5000-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG5000-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.
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- HY-W1051916A
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Biochemical Assay Reagents
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Others
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NH2-PEG2000-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG2000-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.
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- HY-W1051916H
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Biochemical Assay Reagents
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Others
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NH2-PEG400-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG400-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.
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- HY-W1051916B
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Biochemical Assay Reagents
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Others
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NH2-PEG3400-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG3400-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.
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- HY-W1051916I
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Biochemical Assay Reagents
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Others
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NH2-PEG600-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG600-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.
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- HY-W1051916
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Biochemical Assay Reagents
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Others
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NH2-PEG1000-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG1000-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.
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- HY-W1051916D
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Biochemical Assay Reagents
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Others
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NH2-PEG10000-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG10000-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.
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- HY-W460261A
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- HY-W460261D
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- HY-W460261B
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- HY-W460261C
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- HY-D2514
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Fluorescent Dye
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Others
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Cy3-PEG1000-DSPE is a compound for the labeling and visualization of nanoparticles or other materials. Cy3-PEG1000-DSPE has a variety of applications including drug delivery, cellular imaging, tracing of bioprocesses, and the study of interactions at the molecular level.
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- HY-D2518
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Fluorescent Dye
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Others
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Cy3-PEG10000-DSPE is a compound for the labeling and visualization of nanoparticles or other materials. Cy3-PEG10000-DSPE has a variety of applications including drug delivery, cellular imaging, tracing of bioprocesses, and the study of interactions at the molecular level.
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- HY-172276
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Liposome
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Cancer
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DSPE-PEG1000-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG1000-R8 can be used for drug delivery .
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- HY-172483
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Liposome
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Cancer
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DSPE-PEG3000-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG3000-TAASGVRSMH can be used for drug delivery .
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- HY-172481
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Liposome
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Cancer
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DSPE-PEG1000-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG1000-TAASGVRSMH can be used for drug delivery .
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- HY-172511
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Biochemical Assay Reagents
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Others
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m-PEG9-4-nitrophenyl carbonate serves as a PEG linker containing a nitrophenyl carbonate, which is readily displaced by amine nucleophiles to form carbamate bonds under mild conditions. The PEG9 chain bolsters the water solublity of the compound.
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- HY-172482
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Liposome
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Cancer
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DSPE-PEG2000-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG2000-TAASGVRSMH can be used for drug delivery .
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- HY-W1048669A
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Biochemical Assay Reagents
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Others
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Biotin-PEG5000-DMG is a compound composed of biotin, PEG, and myristoyl-sn-glycerol, used for drug delivery. Biotin forms a stable non-covalent bond with streptavidin.
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- HY-W1048669I
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Biochemical Assay Reagents
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Others
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Biotin-PEG3400-DMG is a compound composed of biotin, PEG, and myristoyl-sn-glycerol, used for drug delivery. Biotin forms a stable non-covalent bond with streptavidin.
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- HY-W1048669H
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Biochemical Assay Reagents
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Others
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Biotin-PEG2000-DMG is a compound composed of biotin, PEG, and myristoyl-sn-glycerol, used for drug delivery. Biotin forms a stable non-covalent bond with streptavidin.
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-
- HY-W1048669E
-
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Biochemical Assay Reagents
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Others
|
|
Biotin-PEG1000-DMG is a compound composed of biotin, PEG, and myristoyl-sn-glycerol, used for drug delivery. Biotin forms a stable non-covalent bond with streptavidin.
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-
- HY-172727
-
|
|
Liposome
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Cancer
|
|
DSPE-PEG5000-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG5000-EB1 can be used for drug delivery .
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-
- HY-172686
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG1000-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). CSTSMLKAC is capable of mediating selective homing of phage to ischemic heart tissue. DSPE-PEG1000-CSTSMLKAC can be used for drug delivery .
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-
- HY-172725
-
|
|
Liposome
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Cancer
|
|
DSPE-PEG1000-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG1000-EB1 can be used for drug delivery .
|
-
- HY-P11485
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
PSMA
|
Cancer
|
|
JR11-PEG3-HBED-CC-PSMA-03 (Compound 1) is an RDC-related compound containing the chelating agent HBED-CC, the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-HBED-CC-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 59.2 nM, 57.0 nM, respectively. JR11-PEG3-HBED-CC-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-HBED-CC-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
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-
- HY-P11488
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
PSMA
|
Cancer
|
|
JR11-PEG3-DOTA-PSMA-03 (Compound 2) is an RDC-related compound containing the chelating agent DOTA (HY-W053583), the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-DOTA-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 94.0 nM, 81.8 nM, respectively. JR11-PEG3-DOTA-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-DOTA-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
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-
- HY-182100
-
|
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Liposome
|
Others
|
|
DSPE-PEG1000-MTP is a PEG compound which composed of DSPE and a muscle-targeting peptide (MTP). MTP is a muscle-targeting peptide with the property of targeting muscle tissue. DSPE-PEG1000-MTP can be used for drug delivery .
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-
- HY-182100B
-
|
|
Liposome
|
Others
|
|
DSPE-PEG3400-MTP is a PEG compound which composed of DSPE and a muscle-targeting peptide (MTP). MTP is a muscle-targeting peptide with the property of targeting muscle tissue. DSPE-PEG3400-MTP can be used for drug delivery .
|
-
- HY-182100C
-
|
|
Liposome
|
Others
|
|
DSPE-PEG5000-MTP is a PEG compound which composed of DSPE and a muscle-targeting peptide (MTP). MTP is a muscle-targeting peptide with the property of targeting muscle tissue. DSPE-PEG5000-MTP can be used for drug delivery .
|
-
- HY-182100A
-
|
|
Liposome
|
Others
|
|
DSPE-PEG2000-MTP is a PEG compound which composed of DSPE and a muscle-targeting peptide (MTP). MTP is a muscle-targeting peptide with the property of targeting muscle tissue. DSPE-PEG2000-MTP can be used for drug delivery .
|
-
- HY-W800661
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Tos-PEG3-methyl ester is a PEG linker with tosyl and methyl ester moieties. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG linker increases the water solubility of the compound. Methyl ester can be hydrolyzed under strong basic condition.
|
-
- HY-W590569
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Azido-PEG12-amine is a water soluble PEG compound. The azide group enables Click Chemistry. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The hydrophilic PEG arm increases solubility in aqueous media.
|
-
- HY-172691
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .
|
-
- HY-172690A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .
|
-
- HY-172689
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .
|
-
- HY-Y0873Q
-
|
Polyethylene glycol 20000
|
Environmental Pollutants
Biochemical Assay Reagents
|
Others
|
|
PEG20000 (Polyethylene glycol 20000) can be used as a solubilizer. PEG20000 is a kind of biological materials or organic compounds that are widely used in life science research, can be degraded by bacteria .
|
-
- HY-172690
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .
|
-
- HY-179189H
-
|
Folate-PEG10000-ACA
|
Biochemical Assay Reagents
|
Others
|
|
FA-PEG10000-ACA (Folate-PEG10000-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.
|
-
- HY-W190942
-
|
|
PROTAC Linkers
|
Cancer
|
|
(S, R, S)-AHPC-PEG8-acid is a synthetic PROTAC linker that incorporatess an E3 ligase ligand with a PEG8 linker to empower PROTAC drug R&D. PEG8 increases the compound's aqueous solubility. Acid group is reactive with amine containing molecule.
|
-
- HY-179189B
-
|
Folate-PEG1000-ACA
|
Biochemical Assay Reagents
|
Others
|
|
FA-PEG1000-ACA (Folate-PEG1000-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.
|
-
- HY-179189C
-
|
Folate-PEG2000-ACA
|
Biochemical Assay Reagents
|
Others
|
|
FA-PEG2000-ACA (Folate-PEG2000-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.
|
-
- HY-179189D
-
|
Folate-PEG3400-ACA
|
Biochemical Assay Reagents
|
Others
|
|
FA-PEG3400-ACA (Folate-PEG3400-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.
|
-
- HY-179189E
-
|
Folate-PEG5000-ACA
|
Biochemical Assay Reagents
|
Others
|
|
FA-PEG5000-ACA (Folate-PEG5000-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.
|
-
- HY-179189
-
|
Folate-PEG400-ACA
|
Biochemical Assay Reagents
|
Others
|
|
FA-PEG400-ACA (Folate-PEG400-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.
|
-
- HY-179189A
-
|
Folate-PEG600-ACA
|
Biochemical Assay Reagents
|
Others
|
|
FA-PEG600-ACA (Folate-PEG600-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.
|
-
- HY-174948B
-
|
NHS-PEG3400-Aldehyde
|
Biochemical Assay Reagents
|
Others
|
|
NHS-PEG3400-CHO (NHS-PEG3400-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
- HY-W190941
-
|
3,6,9,12,15-Pentaoxahexacosan-1-ol
|
Biochemical Assay Reagents
|
Others
|
|
C11-PEG6-alcohol (3,6,9,12,15-Pentaoxahexacosan-1-ol) is a linker with an aliphatic carbon chain and a PEG chain. The hydrophilic PEG chain increases the water solubility of the compounds in the aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
|
-
- HY-174948
-
|
NHS-PEG1000-Aldehyde
|
Biochemical Assay Reagents
|
Others
|
|
NHS-PEG1000-CHO (NHS-PEG1000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
- HY-174948A
-
|
NHS-PEG2000-Aldehyde
|
Biochemical Assay Reagents
|
Others
|
|
NHS-PEG2000-CHO (NHS-PEG2000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
- HY-W190955
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-(t-butyl ester-PEG3)-N-bis(PEG3-amine) is a PEG reagent that can easily react with activated NHS esters or carboxylic acid in the presence of EDC or HATU. The t-butyl group can be deprotected under acidic conditions. The hydrophilic PEG spacers increase the compounds water solubility in aqueous media.
|
-
- HY-174948C
-
|
NHS-PEG5000-Aldehyde
|
Biochemical Assay Reagents
|
Others
|
|
NHS-PEG5000-CHO (NHS-PEG5000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
- HY-182101B
-
|
|
Liposome
|
Others
|
|
DSPE-PEG3400-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a muscle-targeting peptide VHPKQHRGGSKGC (HY-P11088). GNYTCEVTELTREGETIIELK is a peptide that can bind to VCAM1. DSPE-PEG3400-GNYTCEVTELTREGETIIELK can be used for drug delivery .
|
-
- HY-172708A
-
|
|
Liposome
|
Neurological Disease
|
|
DSPE-PEG3400-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG3400-PP1 can be used for drug delivery .
|
-
- HY-114661
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-Tos is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-b). m-PEG4-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277) .
|
-
- HY-172504
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG5000-KAA can be used for drug delivery .
|
-
- HY-172473A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG34000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG3400-NGR can be used for drug delivery .
|
-
- HY-182101A
-
|
|
Liposome
|
Others
|
|
DSPE-PEG2000-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a muscle-targeting peptide VHPKQHRGGSKGC (HY-P11088). GNYTCEVTELTREGETIIELK is a peptide that can bind to VCAM1. DSPE-PEG2000-GNYTCEVTELTREGETIIELK can be used for drug delivery .
|
-
- HY-172503A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG3400-KAA can be used for drug delivery .
|
-
- HY-182101
-
|
|
Liposome
|
Others
|
|
DSPE-PEG1000-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a muscle-targeting peptide VHPKQHRGGSKGC (HY-P11088). GNYTCEVTELTREGETIIELK is a peptide that can bind to VCAM1. DSPE-PEG1000-GNYTCEVTELTREGETIIELK can be used for drug delivery .
|
-
- HY-172685
-
|
|
Liposome
|
Others
|
|
DSPE-PEG5000-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG5000-GRGDS can be used for drug delivery .
|
-
- HY-W042501
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG5-Tos is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-c). m-PEG5-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277) .
|
-
- HY-172474
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG5000-NGR can be used for drug delivery .
|
-
- HY-172502
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG1000-KAA can be used for drug delivery .
|
-
- HY-172684A
-
|
|
Liposome
|
Others
|
|
DSPE-PEG3400-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG3400-GRGDS can be used for drug delivery .
|
-
- HY-172709
-
|
|
Liposome
|
Neurological Disease
|
|
DSPE-PEG5000-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG5000-PP1 can be used for drug delivery .
|
-
- HY-172472
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG1000-NGR can be used for drug delivery .
|
-
- HY-172684
-
|
|
Liposome
|
Others
|
|
DSPE-PEG2000-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG2000-GRGDS can be used for drug delivery .
|
-
- HY-172503
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG2000-KAA can be used for drug delivery .
|
-
- HY-172708
-
|
|
Liposome
|
Neurological Disease
|
|
DSPE-PEG2000-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG2000-PP1 can be used for drug delivery .
|
-
- HY-135090
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG8-m is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-d). Tos-PEG8-m is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277) .
|
-
- HY-172683
-
|
|
Liposome
|
Others
|
|
DSPE-PEG1000-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG1000-GRGDS can be used for drug delivery .
|
-
- HY-172473
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG2000-NGR can be used for drug delivery .
|
-
- HY-182101C
-
|
|
Liposome
|
Others
|
|
DSPE-PEG5000-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a muscle-targeting peptide VHPKQHRGGSKGC (HY-P11088). GNYTCEVTELTREGETIIELK is a peptide that can bind to VCAM1. DSPE-PEG5000-GNYTCEVTELTREGETIIELK can be used for drug delivery .
|
-
- HY-172707
-
|
|
Liposome
|
Neurological Disease
|
|
DSPE-PEG1000-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG1000-PP1 can be used for drug delivery .
|
-
- HY-W800652
-
|
|
PROTAC Linkers
|
Cancer
|
|
(S, R, S)-AHPC-PEG4-tosyl is a PROTAC linker that incorporatess an E3 ligase ligand with a PEG4 linker to empower PROTAC drug research & discovery. PEG4 spacer increases the compound's hydrophility. Tosyl group is reactive with amine or other nucleophiles.
|
-
- HY-167791
-
-
- HY-124780
-
|
|
PROTAC Linkers
|
Others
|
|
HOOCCH2O-PEG4-CH2COOH, compound 5, is a symmetric PEG linker, used for the synthesis of the first class of Homo-PROTAC .
|
-
- HY-181499
-
|
|
Proteasome
|
Cancer
|
|
RA190-PEG1-NH2 (Compound S16), RA190 (HY-100739) derivative, is a Proteasome ligand. RA190-PEG1-NH2 can be used to synthesis FKBP12 CAP-TAC degrader RAFKBP12 (HY-181498) .
|
-
- HY-153642
-
-
- HY-160916
-
|
|
Drug Intermediate
|
Others
|
|
N3-PEG8-Oxydiacetamide-Phe-Lys(MMT)-PAB-PNP (compound 18) is a pharmaceutical synthesis intermediate for the SN-38 (HY-13704) derivative .
|
-
- HY-134977
-
|
|
Ras
|
Cancer
|
|
Atrovastatin-PEG3-FITC (compound S31) is a KRAS-PDEδ interaction inhibitor. Atrovastatin-PEG3-FITC acts as a ligand in fluorescence anisotropy assay .
|
-
- HY-151758
-
|
|
ADC Linker
|
Others
|
|
Methyltetrazine-PEG12-NHS ester is a click chemistry reagent containing an azide group. Methyltetrazine-PEG12-NHS ester reacts with compounds containing TCO to form stable covalent bonds .
|
-
- HY-156494
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG9-COOH is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-172497
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG2000-CREKA can be used for drug delivery .
|
-
- HY-172701
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG1000-NYZL1 can be used for drug delivery .
|
-
- HY-172696
-
|
|
Liposome
Collagen
|
Inflammation/Immunology
|
|
DSPE-PEG2000-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG2000-WYRGRL can be used for drug delivery .
|
-
- HY-172496
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG1000-CREKA can be used for drug delivery .
|
-
- HY-172696A
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG3400-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG3400-WYRGRL can be used for drug delivery .
|
-
- HY-156491
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG9-NHS is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-172702A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG3400-NYZL1 can be used for drug delivery .
|
-
- HY-172498
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG5000-CREKA can be used for drug delivery .
|
-
- HY-156475
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG2-COOH is an ADC Linker containing 2 PEG units. Me-Tet-PEG2-COOH can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-172695
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG1000-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG1000-WYRGRL can be used for drug delivery .
|
-
- HY-172497A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG3400-CREKA can be used for drug delivery .
|
-
- HY-156495
-
|
|
ADC Linker
|
Cancer
|
|
Biotin-PEG3-Me-Tet is an ADC Linker containing 3 PEG units. Biotin-PEG3-Me-Tet can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-172697
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG5000-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG5000-WYRGRL can be used for drug delivery .
|
-
- HY-156479
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG3-NHBoc is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156476
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG2-NHS is an ADC Linker containing 2 PEG units. Me-Tet-PEG2-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156478
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG4-NHBoc is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156313
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG4-NHS is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-172702
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG2000-NYZL1 can be used for drug delivery .
|
-
- HY-172703
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG5000-NYZL1 can be used for drug delivery .
|
-
- HY-164792
-
-
- HY-156477
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG8-NHBoc is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156490
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG5-NHS is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156492
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG4-COOH is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156493
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG5-COOH is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-W190914
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TCO-PEG2-TCO is a homebifunctional reagent containing TCO moiety at both ends of the molecule. TCO group specifically and efficiently reacts with tetrazine. The hydrophilic PEG linker increases the solubility of compounds in aqueous media.
|
-
- HY-142740
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Rha-PEG3-SMCC (compound 13) is a agent-linker conjugate for ADC with potent antitumor activity by using SMCC (a protein crosslinker), linked via the noncleavable ADC linker Rha-PEG3.
|
-
- HY-W800631
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Benzyl N1-(PEG1-acid)-N6-(t-Boc)-L-lysinate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-172468
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-CTT2 is a PEG compound which composed of DSPE and a gelatinase inhibitor (CTT2 (CTTHWGFTLC)). CTT2 (CTTHWGFTLC) has the ability to specifically target tumors. DSPE-PEG5000-CTT2 can be used for drug delivery .
|
-
- HY-172470A
-
|
|
Liposome
EGFR
|
Cancer
|
|
DSPE-PEG3400-GE11 is a PEG compound which composed of DSPE and an EGFR targeting peptide (GE11). GE11 can be used for EGFR overexpressed cancer cells. DSPE-PEG3400-GE11 can be used for drug delivery .
|
-
- HY-172466
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-CTT2 is a PEG compound which composed of DSPE and a gelatinase inhibitor (CTT2 (CTTHWGFTLC)). CTT2 (CTTHWGFTLC) has the ability to specifically target tumors. DSPE-PEG1000-CTT2 can be used for drug delivery .
|
-
- HY-172471
-
|
|
Liposome
EGFR
|
Cancer
|
|
DSPE-PEG5000-GE11 is a PEG compound which composed of DSPE and an EGFR targeting peptide (GE11). GE11 can be used for EGFR overexpressed cancer cells. DSPE-PEG5000-GE11 can be used for drug delivery .
|
-
- HY-172275A
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG2000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG2000-pPB can be used for drug delivery .
|
-
- HY-172484
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG1000-LTLRWVGLMS can be used for drug delivery .
|
-
- HY-115414
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-propargyl-PEG8 (compound 16e) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-propargyl-PEG8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-172485A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG3400-LTLRWVGLMS can be used for drug delivery .
|
-
- HY-172467
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-CTT2 is a PEG compound which composed of DSPE and a gelatinase inhibitor (CTT2 (CTTHWGFTLC)). CTT2 (CTTHWGFTLC) has the ability to specifically target tumors. DSPE-PEG2000-CTT2 can be used for drug delivery .
|
-
- HY-172486
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG5000-LTLRWVGLMS can be used for drug delivery .
|
-
- HY-172466A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-CTT2 is a PEG compound which composed of DSPE and a gelatinase inhibitor (CTT2 (CTTHWGFTLC)). CTT2 (CTTHWGFTLC) has the ability to specifically target tumors. DSPE-PEG1000-CTT2 can be used for drug delivery .
|
-
- HY-172275
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG1000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG1000-pPB can be used for drug delivery .
|
-
- HY-172469
-
|
|
Liposome
EGFR
|
Cancer
|
|
DSPE-PEG1000-GE11 is a PEG compound which composed of DSPE and an EGFR targeting peptide (GE11). GE11 can be used for EGFR overexpressed cancer cells. DSPE-PEG1000-GE11 can be used for drug delivery .
|
-
- HY-172275B
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG5000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG5000-pPB can be used for drug delivery .
|
-
- HY-172275C
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG3400-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG3400-pPB can be used for drug delivery .
|
-
- HY-172485
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG2000-LTLRWVGLMS can be used for drug delivery .
|
-
- HY-171728
-
|
|
Liposome
|
Metabolic Disease
|
|
Azide-PEG2-amide-C14-COOH (Compound LP-379-p) is a lipid-containing compound. Azide-PEG2-amide-C14-COOH facilitates the delivery of oligonucleotide-based reagents to certain cell types or adipose tissue .
|
-
- HY-172352
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PEG900 tosylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-172352A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PEG2000 tosylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-172723A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG3400-T7 can be used for drug delivery .
|
-
- HY-172724
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG5000-T7 can be used for drug delivery .
|
-
- HY-182099B
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-DHLASLWWGTEL is a PEG compound which composed of DSPE and a GPC3 targeting peptide DHLASLWWGTEL. The DHLASLWWGTEL peptide partially and specifically binds to GPC3-positive cells, achieving precise targeting. DSPE-PEG3400-DHLASLWWGTEL can be used for drug delivery .
|
-
- HY-182092
-
|
|
Liposome
|
Others
|
|
DSPE-PEG1000-Asp6 is a PEG compound which composed of DSPE and a Asp6 peptide. DSPE-PEG1000-Asp6 achieves bone-targeted delivery of drugs or imaging agents by binding to bone tissue with the Asp6 peptide through high affinity .
|
-
- HY-182092A
-
|
|
Liposome
|
Others
|
|
DSPE-PEG5000-Asp6 is a PEG compound which composed of DSPE and a Asp6 peptide. DSPE-PEG5000-Asp6 achieves bone-targeted delivery of drugs or imaging agents by binding to bone tissue with the Asp6 peptide through high affinity .
|
-
- HY-182099A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-DHLASLWWGTEL is a PEG compound which composed of DSPE and a GPC3 targeting peptide DHLASLWWGTEL. The DHLASLWWGTEL peptide partially and specifically binds to GPC3-positive cells, achieving precise targeting. DSPE-PEG2000-DHLASLWWGTEL can be used for drug delivery .
|
-
- HY-182092C
-
|
|
Liposome
|
Others
|
|
DSPE-PEG3400-Asp6 is a PEG compound which composed of DSPE and a Asp6 peptide. DSPE-PEG3400-Asp6 achieves bone-targeted delivery of drugs or imaging agents by binding to bone tissue with the Asp6 peptide through high affinity .
|
-
- HY-140696D
-
|
mPEG10000-Hydroxy; Polyethylene glycol monomethyl ether 10000
|
Environmental Pollutants
PROTAC Linkers
|
Infection
|
|
m-PEG10000-OH (mPEG10000-Hydroxy; Polyethylene glycol monomethyl ether 10000) is a hydroxyl-terminated methoxylated polyethylene glycol (PEG-based) compound that serves as a linker for PROTACs. m-PEG10000-OH is applicable to research on healthcare-associated infections .
|
-
- HY-158985
-
|
|
AUTACs
Autophagy
|
Cancer
|
|
Amino-PEG3-2G degrader-1 (compound ) is a conjugate of a PEG Linker and a pyrazole-linked FBnG tag for ubiquitin-proteasome system (UPS) induction. Amino-PEG3-2G degrader-1 can be used to synthesize autophagy-targeting chimeras (AUTACs) .
|
-
- HY-158768
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Amino-PEG4-GGFG-Dxd (Compound 13-7) is a drug-linker conjugate for ADC. Amino-PEG4-GGFG-Dxd is composed of Dxd (HY-13631D) and a linker. Amino-PEG4-GGFG-Dxd can be used for synthesis of ADCs
|
-
- HY-W1120572
-
|
Boc-NH-PEG20-CH2CH2NH2
|
Biochemical Assay Reagents
|
Others
|
|
t-Boc-N-Amido-PEG20-amine (Boc-NH-PEG20-CH2CH2NH2) is a compound composed of NH2, PEG units and t-Boc-N-Amido, which can be used for drug delivery.
|
-
- HY-174906
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Bis-PEG1000-COOH is a disubstituted PEG derivative with the same functional group. The carboxylic acid group in Bis-PEG1000-COOH can react with other compounds containing amino, hydroxyl and other functional groups to form stable chemical bonds, which can be used for drug delivery .
|
-
- HY-W590583
-
|
|
PROTAC Linkers
|
Cancer
|
|
(S, R, S)-AHPC-PEG6-Azide is a click chemistry PROTAC linker that incorporates an E3 ligase ligand with a PEG6 arm to empower PROTAC research & discovery. The hydrophilic PEG spacer increases the solubility of a compound in aqueous media. Azide enables click chemistry with alkyne, DBCO, or BCN molecule.
|
-
- HY-182099
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-DHLASLWWGTEL is a PEG compound which composed of DSPE and a GPC3 targeting peptide DHLASLWWGTEL. The DHLASLWWGTEL peptide partially and specifically binds to GPC3-positive cells, achieving precise targeting. DSPE-PEG1000-DHLASLWWGTEL can be used for drug delivery .
|
-
- HY-182099C
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-DHLASLWWGTEL is a PEG compound which composed of DSPE and a GPC3 targeting peptide DHLASLWWGTEL. The DHLASLWWGTEL peptide partially and specifically binds to GPC3-positive cells, achieving precise targeting. DSPE-PEG5000-DHLASLWWGTEL can be used for drug delivery .
|
-
- HY-182092B
-
|
|
Liposome
|
Others
|
|
DSPE-PEG2000-Asp6 is a PEG compound which composed of DSPE and a Asp6 peptide. DSPE-PEG2000-Asp6 achieves bone-targeted delivery of drugs or imaging agents by binding to bone tissue with the Asp6 peptide through high affinity .
|
-
- HY-172722
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG1000-T7 can be used for drug delivery .
|
-
- HY-W924949
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Others
|
|
Pomalidomide-PEG3-OH (compound 53a) is an E3 Ligase Ligand-Linker Conjugates consisting of a pomalidomide (HY-10984)-based cereblon ligand and a 2-unit PEG linker .
|
-
- HY-160788
-
-
- HY-148263
-
|
|
Fluorescent Dye
|
Cancer
|
|
Biotin-PEG2000-Thiol is an active compound. Biotin-PEG2000-Thiol is pegylated by binding to streptavidin or antibiotin with high affinity and specificity. Biotin-PEG2000-Thiol can modify biomolecules, proteins, peptides and other small molecule materials. Biotin-PEG2000-Thiol is widely used in the research of agent release and nano new materials .
|
-
- HY-W924948
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Others
|
|
Pomalidomide-PEG3-OH (compound 53b) is an E3 Ligase Ligand-Linker Conjugates consisting of a pomalidomide (HY-10984)-based cereblon ligand and a 3-unit PEG linker .
|
-
- HY-172491
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-ESBP is a PEG compound which composed of DSPE and a E-selectin-binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells .
|
-
- HY-172491A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-ESBP is a PEG compound which composed of DSPE and a E-selectin-binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells .
|
-
- HY-172490
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-ESBP is a PEG compound which composed of DSPE and a E-selectin-binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells .
|
-
- HY-172492
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-ESBP is a PEG compound which composed of DSPE and a E-selectin-binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells .
|
-
- HY-W1123941
-
|
Dopamine-PEG9-Azide
|
Biochemical Assay Reagents
|
Others
|
|
Dopamine-PEG-N3 (Dopamine-PEG-Azide is a compound composed of dopamine, PEG segments and an azide group (-N3). Dopamine-PEG-N3 can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials. Dopamine-PEG-N3 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group.
|
-
- HY-161133
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Lenalidomide 4'-PEG1-azide (Compound 4g) is a lenalidomide-derived azide. Lenalidomide 4'-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide 4'-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. .
|
-
- HY-W451433
-
|
|
Biochemical Assay Reagents
|
Others
|
|
OTs-PEG1-NHCbz is a PEG linker containing a tosyl group and benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of the compound in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
|
-
- HY-140895B
-
|
Biotin-PEG10000-NH2
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG10000-Amine (Biotin-PEG10000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
-
- HY-172280A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG21000-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG2000-Octreotide can be used for drug delivery .
|
-
- HY-176206E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG20000-COOH is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG20000-COOH can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
|
-
- HY-179678
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Macropa-PEG4-TPF (Compound 7g) is a bifunctional chelator. Macropa-PEG4-TPF can be conjugated to lysine residues on YS5, with an average of about 2.6 chelators per antibody. Macropa-PEG4-TPF can be used for PET imaging studies .
|
-
- HY-140895C
-
|
Biotin-PEG20000-NH2
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG20000-Amine (Biotin-PEG20000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
-
- HY-130407
-
|
|
PROTAC Linkers
|
Cancer
|
|
Lipoamido-PEG3-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Lipoamido-PEG3-OH (compound TA-TEG-G2CN) can be used in the formation of a highly stable, dendronized gold nanoparticle (AuNP)-based drug delivery platform .
|
-
- HY-172280
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG1000-Octreotide can be used for drug delivery .
|
-
- HY-172699A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG3400-ANG can be used for drug delivery .
|
-
- HY-156301A
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG8-NH2 (hydrochloride) is an ADC Linker containing 2 PEG units. Me-Tet-PEG8-NH2 (hydrochloride) can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-176206D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG10000-COOH is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG10000-COOH can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
|
-
- HY-176206H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG40000-COOH is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG40000-COOH can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
|
-
- HY-172281
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG1000-CCK8 is a PEG compound which composed of DSPE and a Cholecystokinin-8 (CCK8). Cholecystokinin-8 has the activity of peptide regulating gallbladder contraction and digestive system function. DSPE-PEG1000-CCK8 can be used for drug delivery .
|
-
- HY-140895D
-
|
Biotin-PEG40000-NH2
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG40000-Amine (Biotin-PEG40000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
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-
- HY-172280C
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG3400-Octreotide can be used for drug delivery .
|
-
- HY-172281B
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG5000-CCK8 is a PEG compound which composed of DSPE and a Cholecystokinin-8 (CCK8). Cholecystokinin-8 has the activity of peptide regulating gallbladder contraction and digestive system function. DSPE-PEG5000-CCK8 can be used for drug delivery .
|
-
- HY-176206
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG1000-COOH is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG1000-COOH can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
|
-
- HY-172698
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG1000-ANG can be used for drug delivery .
|
-
- HY-176206A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG2000-COOH is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG2000-COOH can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
|
-
- HY-172700
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG5000-ANG can be used for drug delivery .
|
-
- HY-W591272
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG3-NH2 is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-NH2 can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups .
|
-
- HY-172280B
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG5000-Octreotide can be used for drug delivery .
|
-
- HY-W1113139
-
|
|
Biochemical Assay Reagents
|
Others
|
|
H2N-PEG4-C3-OH is a PEG linker with a terminal amino group that can react with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. Hydroxyl group can react with a variety of functional groups. PEG spacer improves the compound's aqueous solubility.
|
-
- HY-176206B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG3400-COOH is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG3400-COOH can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
|
-
- HY-140895A
-
|
Biotin-PEG5000-NH2
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG5000-Amine (Biotin-PEG5000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
-
- HY-176206C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG5000-COOH is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG5000-COOH can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
|
-
- HY-172281A
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG2000-CCK8 is a PEG compound which composed of DSPE and a Cholecystokinin-8 (CCK8). Cholecystokinin-8 has the activity of peptide regulating gallbladder contraction and digestive system function. DSPE-PEG2000-CCK8 can be used for drug delivery .
|
-
- HY-156748
-
|
|
Drug-Linker Conjugates for ADC
Topoisomerase
|
Cancer
|
|
MC-PEG2-VA-PAB-Exatecan (Compound DL-18) is a Drug-Linker Conjugates for ADC. MC-PEG2-VA-PAB-Exatecan consists of Exatecan (HY-13631) and a linker. MC-PEG2-VA-PAB-Exatecan can be used for synthesis of ADCs .
|
-
- HY-W591272A
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG3-NH2 hydrochloride is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-NH2 hydrochloride can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups .
|
-
- HY-156300
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG4-NH2 is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NH2 can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-W591373
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-PEG4-Val-Ala-PAB is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. The DBCO groups is commonly used for Click Chemistry reactions. PEG spacer improves the compound's aqueous solubility.
|
-
- HY-172294
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mes-PEG2-CH2-t-butyl ester is a PEG linker consisting of a PEG2 linker for improved water-solubility of the compound and a t-butyl ester group which can be deprotected under acidic conditions. The mesylate serves as an excellent leaving group, offering all the advantages without the limitation of having an acidic proton that could react with nucleophiles.
|
-
- HY-177204A
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG1000-WLSEAGPVVTVRALRGTGSW is a PEG compound which composed of DSPE and a cardiomyocyte specific peptide (WLSEAGPVVTVRALRGTGSW) (HY-P3436). WLSEAGPVVTVRALRGTGSW exhibits high cardiomyocyte targeting primarily through selective binding to specific receptors or molecules on the surface of cardiomyocytes. DSPE-PEG1000-WLSEAGPVVTVRALRGTGSW can be used for drug delivery .
|
-
- HY-172464
-
|
|
Liposome
Integrin
|
Cancer
|
|
DSPE-PEG2000-cRGD is a PEG compound which composed of DSPE and an αvβ3 targeting peptide (cRGD). cRGD peptide can specifically bind to αvβ3 on the surface of many cancer cells and neovascular cells. DSPE-PEG2000-cRGD can be used for drug delivery .
|
-
- HY-177204B
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG3400-WLSEAGPVVTVRALRGTGSW is a PEG compound which composed of DSPE and a cardiomyocyte specific peptide (WLSEAGPVVTVRALRGTGSW) (HY-P3436). WLSEAGPVVTVRALRGTGSW exhibits high cardiomyocyte targeting primarily through selective binding to specific receptors or molecules on the surface of cardiomyocytes. DSPE-PEG3400-WLSEAGPVVTVRALRGTGSW can be used for drug delivery .
|
-
- HY-177204C
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG5000-WLSEAGPVVTVRALRGTGSW is a PEG compound which composed of DSPE and a cardiomyocyte specific peptide (WLSEAGPVVTVRALRGTGSW) (HY-P3436). WLSEAGPVVTVRALRGTGSW exhibits high cardiomyocyte targeting primarily through selective binding to specific receptors or molecules on the surface of cardiomyocytes. DSPE-PEG5000-WLSEAGPVVTVRALRGTGSW can be used for drug delivery .
|
-
- HY-172464A
-
|
|
Liposome
Integrin
|
Cancer
|
|
DSPE-PEG3400-cRGD is a PEG compound which composed of DSPE and an αvβ3 targeting peptide (cRGD). cRGD peptide can specifically bind to αvβ3 on the surface of many cancer cells and neovascular cells. DSPE-PEG3400-cRGD can be used for drug delivery .
|
-
- HY-172463
-
|
|
Liposome
Integrin
|
Cancer
|
|
DSPE-PEG1000-cRGD is a PEG compound which composed of DSPE and an αvβ3 targeting peptide (cRGD). cRGD peptide can specifically bind to αvβ3 on the surface of many cancer cells and neovascular cells. DSPE-PEG1000-cRGD can be used for drug delivery .
|
-
- HY-W440891
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG1000-OH is a hydroxyl terminated phospholipid PEG polymer. The hydrophobic tails allow for the encapsulation and congregation of other hydrophobic drugs. The polymer can be used to prepare liposomes or lipid nanoparticles. Hydroxyl terminal can further derivatize the compound.
|
-
- HY-179193E
-
|
N3-PEG5000-OPSS
|
Biochemical Assay Reagents
|
Others
|
|
Azide-PEG5000-OPSS (N3-PEG5000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG5000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-179193C
-
|
N3-PEG2000-OPSS
|
Biochemical Assay Reagents
|
Others
|
|
Azide-PEG2000-OPSS (N3-PEG2000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG2000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-179193H
-
|
N3-PEG10000-OPSS
|
Biochemical Assay Reagents
|
Others
|
|
Azide-PEG10000-OPSS (N3-PEG10000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG10000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-179193B
-
|
N3-PEG1000-OPSS
|
Biochemical Assay Reagents
|
Others
|
|
Azide-PEG1000-OPSS (N3-PEG1000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG1000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-179193D
-
|
N3-PEG3400-OPSS
|
Biochemical Assay Reagents
|
Others
|
|
Azide-PEG3400-OPSS (N3-PEG3400-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG3400-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-179193A
-
|
N3-PEG600-OPSS
|
Biochemical Assay Reagents
|
Others
|
|
Azide-PEG600-OPSS (N3-PEG600-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG600-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-179193
-
|
N3-PEG400-OPSS
|
Biochemical Assay Reagents
|
Others
|
|
Azide-PEG400-OPSS (N3-PEG400-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG400-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W144703
-
|
9-Aminoheptadecane
|
Biochemical Assay Reagents
|
Others
|
|
Heptadecan-9-amine (9-Aminoheptadecane) is PEG linker containing a maleimide and TFP ester end group. Maleimide groups are reactive with thiols between pH 6.5 and 7.5. The TFP ester can react with primary amine groups and is also less susceptible to undergo hydrolysis compared to NHS ester. The hydrophilic PEG chains increase the water solubility of a compound in aqueous media. Longer PEG chains have improved water solubility relative to shorter PEG chains.
|
-
- HY-180447
-
-
- HY-139332
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Pomalidomide 4'-PEG6-azide (compound 33e) is the E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Pomalidomide 4'-alkylC3-acid can be used to synthesize PROTACs .
|
-
- HY-176390
-
|
|
PROTAC Linkers
|
Others
|
|
Adamantan-C-amide-PEG2-C2-amine (Compound 8) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs, such as PROTAC β-NF-JQ1 (HY-130256) .
|
-
- HY-172271C
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-LyP-1 is a PEG compound which composed of DSPE and a nine residue peptide (LyP-1) (HY-P2526). LyP-1 targets tumor-associated lymphatic vessels and macrophages .
|
-
- HY-149039
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Amine-PEG4-amido-tri-(carboxyethoxymethyl)-methane is a organic compounds, acts as a linker used to synthesize multifunctional molecules.
|
-
- HY-153172
-
|
|
Others
|
Others
|
|
Phenylbenzothiazole-PEG4-OH (compound 1) can study spinal cord injury and promote spine formation .
|
-
- HY-172477
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG5000-YIGSR can be used for drug delivery .
|
-
- HY-172479
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-F3 is a PEG compound which composed of DSPE and a nucleolin targeting peptide (F3). F3 peptide can specifically bind to cell surface nucleolin and undergo an effective cell surface to nucleus transport. DSPE-PEG2000-F3 can be used for drug delivery .
|
-
- HY-172479A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-F3 is a PEG compound which composed of DSPE and a nucleolin targeting peptide (F3). F3 peptide can specifically bind to cell surface nucleolin and undergo an effective cell surface to nucleus transport. DSPE-PEG3400-F3 can be used for drug delivery .
|
-
- HY-172475
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG1000-YIGSR can be used for drug delivery .
|
-
- HY-W800712
-
|
|
Biochemical Assay Reagents
|
Others
|
|
t-Boc-N-Amido-PEG11-Tos is a PEG linker containing a tosyl group and Boc-protected amine group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form a free amine.
|
-
- HY-W460275
-
|
|
Biochemical Assay Reagents
|
Others
|
|
t-Boc-N-Amido-PEG5-Tos is a PEG linker containing a tosyl group and Boc-protected amine group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form a free amine.
|
-
- HY-172478
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-F3 is a PEG compound which composed of DSPE and a nucleolin targeting peptide (F3). F3 peptide can specifically bind to cell surface nucleolin and undergo an effective cell surface to nucleus transport. DSPE-PEG1000-F3 can be used for drug delivery .
|
-
- HY-172480
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-F3 is a PEG compound which composed of DSPE and a nucleolin targeting peptide (F3). F3 peptide can specifically bind to cell surface nucleolin and undergo an effective cell surface to nucleus transport. DSPE-PEG5000-F3 can be used for drug delivery .
|
-
- HY-172476
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG2000-YIGSR can be used for drug delivery .
|
-
- HY-172476A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG3400-YIGSR can be used for drug delivery .
|
-
- HY-169089A
-
|
|
Drug Derivative
|
Cancer
|
|
RP-182-PEG3-K(palmitic acid)-NH2 (Compound 1a) TFA is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K(palmitic acid)-NH2 TFA inhibits CD206 high M2-like macrophage (IC50 of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K(palmitic acid)-NH2 TFA exhibits antitumor efficacy in mouse B16 melanoma allografts .
|
-
- HY-145177
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc can be used for the synthesis of PROTAC BET degrader . (From patent WO2017180417A1 compound s7).
|
-
- HY-169089
-
|
|
Drug Derivative
|
Cancer
|
|
RP-182-PEG3-K palmitic acid-NH2 (Compound 1a) is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K palmitic acid-NH2 inhibits CD206 high M2-like macrophage (IC50 of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K palmitic acid-NH2 exhibits antitumor efficacy in mouse B16 melanoma allografts .
|
-
- HY-103603C
-
|
|
E3 Ligase Ligand-Linker Conjugates
Drug Isomer
|
Cancer
|
|
(S,S,S)-AHPC-PEG2-NH2 is an isomer of Compound 15b. Compound 15b is a conjugate of a VHL ligand and linker. Compound 15b can be used to synthesize PROTAC. Compound 15b can be used in leukemia research .
|
-
- HY-181043
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
CRBN ligand-895-PEG2-N3 (Compound 15) is a synthetic E3 ligase linker conjugate that can be used for the synthesis of PROTACs, such as PROTAC HDAC8 Degrader-4 (HY-181024) .
|
-
- HY-148380
-
-
- HY-172692
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-TH is a PEG compound which composed of DSPE and a pH-responsive cell penetrating peptide (TH). TH is activated in an acidic environment (such as the tumor microenvironment) and can selectively carry small molecules, oligonucleotides, proteins, etc. into tumor cells .
|
-
- HY-176766
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Mal-PEG8-Val-Ala-Exatecan (Compound 1033) is a Drug-Linker Conjugates for ADC, which is composed of Exatecan (HY-13631) and a linker. Mal-PEG8-Val-Ala-Exatecan can be used for ADC synthesis .
|
-
- HY-172694
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-TH is a PEG compound which composed of DSPE and a pH-responsive cell penetrating peptide (TH). TH is activated in an acidic environment (such as the tumor microenvironment) and can selectively carry small molecules, oligonucleotides, proteins, etc. into tumor cells .
|
-
- HY-172693
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-TH is a PEG compound which composed of DSPE and a pH-responsive cell penetrating peptide (TH). TH is activated in an acidic environment (such as the tumor microenvironment) and can selectively carry small molecules, oligonucleotides, proteins, etc. into tumor cells .
|
-
- HY-W1123941A
-
|
Dopamine-PEG-Azide
|
Biochemical Assay Reagents
|
Others
|
|
Dopamine-PEG13-N3 (Dopamine-PEG-Azide) is a compound composed of dopamine, PEG segments and an azide group (-N3). Dopamine-PEG13-N3 can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials. Dopamine-PEG13-N3 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group.
|
-
- HY-172302
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Phthalimide-PEG2-Boc is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W472959
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Bis-PEG3-phthalimide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W800835
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Bromo-PEG3-Amine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-180501
-
-
- HY-W800675
-
|
|
Biochemical Assay Reagents
|
Others
|
|
AZD-PEG2-azide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-172304
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Phthalimide-PEG1-amine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-182097A
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG3400-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a peptide mimicking the function of CD47 (GNYTCEVTELSREGKTVIELK). Modifying the surface of LNPs with GNYTCEVTELSREGKTVIELK significantly reduced the recognition and clearance of LNPs by the mononuclear phagocytic system (MPS), and decreased their accumulation in non-target tissues such as the liver and spleen. DSPE-PEG3400-GNYTCEVTELTREGETIIELK can be used for drug delivery .
|
-
- HY-172499
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG1000-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.
|
-
- HY-182097
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG1000-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a peptide mimicking the function of CD47 (GNYTCEVTELSREGKTVIELK). Modifying the surface of LNPs with GNYTCEVTELSREGKTVIELK significantly reduced the recognition and clearance of LNPs by the mononuclear phagocytic system (MPS), and decreased their accumulation in non-target tissues such as the liver and spleen. DSPE-PEG1000-GNYTCEVTELTREGETIIELK can be used for drug delivery .
|
-
- HY-172495
-
|
|
Liposome
Integrin
|
Cancer
|
|
DSPE-PEG3000-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG3000-iRGD can be used for drug delivery .
|
-
- HY-172493
-
|
|
Liposome
Integrin
|
Cancer
|
|
DSPE-PEG1000-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG1000-iRGD can be used for drug delivery .
|
-
- HY-172494
-
|
|
Liposome
Integrin
Drug Intermediate
Complement System
|
Cancer
|
|
DSPE-PEG2000-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG2000-iRGD can be used for agent delivery .
|
-
- HY-W190928
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-(Azido-PEG2-amido)-1,3-bis-(tert-butyldimethylsilanoxy)propane is a PEG linker containing a TBDMS acid labile, alcohol protecting group. The azide group is able to participate in copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN to generate triazole linkages. The hydrophilic PEG linker increases the solubility properties of compounds in aqueous media.
|
-
- HY-182097B
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG5000-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a peptide mimicking the function of CD47 (GNYTCEVTELSREGKTVIELK). Modifying the surface of LNPs with GNYTCEVTELSREGKTVIELK significantly reduced the recognition and clearance of LNPs by the mononuclear phagocytic system (MPS), and decreased their accumulation in non-target tissues such as the liver and spleen. DSPE-PEG5000-GNYTCEVTELTREGETIIELK can be used for drug delivery .
|
-
- HY-172501
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG5000-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.
|
-
- HY-172494A
-
|
|
Liposome
Integrin
|
Cancer
|
|
DSPE-PEG3400-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG3400-iRGD can be used for drug delivery .
|
-
- HY-172500A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG3400-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.
|
-
- HY-172500
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG2000-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.
|
-
- HY-156301
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Methyltetrazine-amido-PEG8-amine Trifluoroacetate is a heterobifunctional linker containing a terminal methyltetrazine, which can react with TCO-containing compounds without the catalysis of Cu or elevated temperatures, and terminal amine, which reacts with NHS ester specifically and efficiently. The PEG spacer enhances water solubility.
|
-
- HY-180447A
-
-
- HY-186088
-
|
|
Drug Intermediate
|
Others
|
|
DOTA-tris (t-Bu) ester-PEG3-C2-amine (Compound 9) is a conjugate of DOTA-based chelator and linker, bearing tris (t-Bu) ester and PEG3-C2-amine functional groups. DOTA-tris (t-Bu) ester-PEG3-C2-amine can be conjugated to payloads via bioorthogonal click chemistry for targeted delivery .
|
-
- HY-W591374
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-PEG4-Val-Ala-PAB-PNP is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. The DBCO groups is commonly used for Click Chemistry reactions. PEG spacer improves the compound's aqueous solubility. PNP is a good leaving group.
|
-
- HY-172706
-
|
|
Liposome
nAChR
|
Neurological Disease
|
|
DSPE-PEG5000-RVG29 is a PEG compound which composed of DSPE and a Rabies virus glycoprotein 29 (RVG29). RVG29 can bind specifically to the nicotinic acetylcholine receptor (nAChR) at the blood-brain barrier (BBB) and cross over the BBB .
|
-
- HY-172272B
-
|
|
Liposome
VEGFR
|
Cancer
|
|
DSPE-PEG5000-A7R is a PEG compound which composed of DSPE and a tumor vascular targeting peptide (A7R). A7R exhibits high affinity and specificity for VEGFR-2, which is overexpressed in various tumors .
|
-
- HY-172272A
-
|
|
Liposome
VEGFR
|
Cancer
|
|
DSPE-PEG2000-A7R is a PEG compound which composed of DSPE and a tumor vascular targeting peptide (A7R). A7R exhibits high affinity and specificity for VEGFR-2, which is overexpressed in various tumors .
|
-
- HY-172704
-
|
|
Liposome
nAChR
|
Cancer
|
|
DSPE-PEG1000-RVG29 is a PEG compound which composed of DSPE and a Rabies virus glycoprotein 29 (RVG29). RVG29 can bind specifically to the nicotinic acetylcholine receptor (nAChR) at the blood-brain barrier (BBB) and cross over the BBB .
|
-
- HY-172272
-
|
|
Liposome
VEGFR
|
Cancer
|
|
DSPE-PEG1000-A7R is a PEG compound which composed of DSPE and a tumor vascular targeting peptide (A7R). A7R exhibits high affinity and specificity for VEGFR-2, which is overexpressed in various tumors .
|
-
- HY-172272C
-
|
|
Liposome
VEGFR
|
Cancer
|
|
DSPE-PEG3400-A7R is a PEG compound which composed of DSPE and a tumor vascular targeting peptide (A7R). A7R exhibits high affinity and specificity for VEGFR-2, which is overexpressed in various tumors .
|
-
- HY-Y0873A1
-
-
- HY-Y0873A9
-
|
Polyethylene glycol 2000000
|
Biochemical Assay Reagents
|
Others
|
|
PEG2000000 (Polyethylene glycol 2000000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
-
- HY-Y0873A2
-
|
Polyethylene glycol 600000
|
Biochemical Assay Reagents
|
Others
|
|
PEG600000 (Polyethylene glycol 600000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
-
- HY-Y0873A5
-
|
Polyethylene glycol 200000
|
Biochemical Assay Reagents
|
Others
|
|
PEG200000 (Polyethylene glycol 200000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
-
- HY-Y0873A7
-
|
Polyethylene glycol 900000
|
Biochemical Assay Reagents
|
Others
|
|
PEG900000 (Polyethylene glycol 900000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
-
- HY-Y0873A4
-
|
Polyethylene glycol 4000000
|
Biochemical Assay Reagents
|
Others
|
|
PEG4000000 (Polyethylene glycol 4000000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
-
- HY-Y0873A6
-
|
Polyethylene glycol 400000
|
Biochemical Assay Reagents
|
Others
|
|
PEG400000 (Polyethylene glycol 400000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
-
- HY-Y0873B1
-
|
Polyethylene glycol 8000000
|
Biochemical Assay Reagents
|
Others
|
|
PEG8000000 (Polyethylene glycol 8000000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
-
- HY-W190946
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Hydroxy-PEG3-2-methylacrylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-Y0873A3
-
|
Polyethylene glycol 1000000
|
Biochemical Assay Reagents
|
Others
|
|
PEG1000000 (Polyethylene glycol 1000000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
-
- HY-Y0873A8
-
|
Polyethylene glycol 5000000
|
Biochemical Assay Reagents
|
Others
|
|
PEG5000000 (Polyethylene glycol 5000000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
-
- HY-W1123941C
-
|
Dopamine-PEG2000-Azide
|
Biochemical Assay Reagents
|
Others
|
|
Dopamine-PEG2000-N3 (Dopamine-PEG2000-Azide) is a compound composed of dopamine, PEG segments and an azide group (-N3). Dopamine-PEG2000-N3 can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials. Dopamine-PEG2000-N3 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group.
|
-
- HY-W1123941H
-
|
Dopamine-PEG10000-Azide
|
Biochemical Assay Reagents
|
Others
|
|
Dopamine-PEG10000-N3 (Dopamine-PEG10000-Azide) is a compound composed of dopamine, PEG segments and an azide group (-N3). Dopamine-PEG10000-N3 can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials. Dopamine-PEG10000-N3 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group.
|
-
- HY-W1123941E
-
|
Dopamine-PEG5000-Azide
|
Biochemical Assay Reagents
|
Others
|
|
Dopamine-PEG5000-N3 (Dopamine-PEG5000-Azide) is a compound composed of dopamine, PEG segments and an azide group (-N3). Dopamine-PEG5000-N3 can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials. Dopamine-PEG5000-N3 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group.
|
-
- HY-W1123941B
-
|
Dopamine-PEG1000-Azide
|
Biochemical Assay Reagents
|
Others
|
|
Dopamine-PEG1000-N3 (Dopamine-PEG1000-Azide) is a compound composed of dopamine, PEG segments and an azide group (-N3). Dopamine-PEG1000-N3 can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials. Dopamine-PEG1000-N3 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group.
|
-
- HY-W1123941D
-
|
Dopamine-PEG3400-Azide
|
Biochemical Assay Reagents
|
Others
|
|
Dopamine-PEG3400-N3 (Dopamine-PEG3400-Azide) is a compound composed of dopamine, PEG segments and an azide group (-N3). Dopamine-PEG3400-N3 can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials. Dopamine-PEG3400-N3 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group.
|
-
- HY-156307
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG3-Maleimide is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-172488A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG3400-K237 can be used for drug delivery .
|
-
- HY-172489
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG5000-K237 can be used for drug delivery .
|
-
- HY-172488
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG2000-K237 can be used for drug delivery .
|
-
- HY-130390
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-O-C1-NHS ester (compound 8) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-O-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-172487
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG1000-K237 can be used for drug delivery .
|
-
- HY-156312
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG8-Maleimide is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-156308
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG4-Maleimide is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-W800670
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-amido-PEG5-alkyne is a PEG linker containing a maleimide group and an alkyne. The hydrophilic PEG spacer increases solubility in aqueous media. The alkyne group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-W800666
-
|
|
Biochemical Assay Reagents
|
Others
|
|
5-(Tetrahydro-2H-pyran-2-yloxy)pent-3-yn-1-peg4-azide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-164637
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Aniline-PEG3-C1-Boc (compound D-1) is an intermediate of cytotoxic drug linker polymer. Aniline-PEG3-C1-Boc can be used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-49637
-
-
- HY-172308
-
|
|
Biochemical Assay Reagents
|
Others
|
|
t-Boc-aminooxy-PEG4-phthalimide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-156166
-
-
- HY-168222
-
-
- HY-130182
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG8-NH2 (compound 3b) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-NH2 is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG8-NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-177205C
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG5000-CRPPR is a PEG compound which composed of DSPE and a?Heart-homing peptide?(CRPPR) (HY-P10641). CRPPR is a linear peptide containing arginine that has the ability to specifically bind to the cardiac endothelium and uses cysteine-rich protein-2 (CRIP-2) as its receptor. DSPE-PEG5000-CGKRK can be used for drug delivery .
|
-
- HY-177205A
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG1000-CRPPR is a PEG compound which composed of DSPE and a?Heart-homing peptide?(CRPPR) (HY-P10641). CRPPR is a linear peptide containing arginine that has the ability to specifically bind to the cardiac endothelium and uses cysteine-rich protein-2 (CRIP-2) as its receptor. DSPE-PEG1000-CGKRK can be used for drug delivery .
|
-
- HY-177205B
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG3400-CRPPR is a PEG compound which composed of DSPE and a?Heart-homing peptide?(CRPPR) (HY-P10641). CRPPR is a linear peptide containing arginine that has the ability to specifically bind to the cardiac endothelium and uses cysteine-rich protein-2 (CRIP-2) as its receptor. DSPE-PEG3400-CGKRK can be used for drug delivery .
|
-
- HY-156214
-
|
AP1867-PEG2-JQ1; AP-PEG2-JQ1
|
Epigenetic Reader Domain
|
Others
|
|
NICE-01 (AP1867-PEG2-JQ1; AP-PEG2-JQ1) is a bifunctional compound that bind to proteins in separate cellular compartments that can induce nuclear import of cytosolic cargoes, using nuclear-localized bromodomain-containing protein 4 (BRD4) as a “carrier” for co-import and nuclear trapping of cytosolic proteins .
|
-
- HY-131158
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
DBCO-PEG3-Glu-VC-PABC-MMAF (compound s19b) is a drug-linker conjugate for ADC by using the tubulin inhibitor, MMAF (HY-15579), linked via cathepsin cleavable DBCO-PEG3-Glu-VC-PABC. DBCO-PEG3-Glu-VC-PABC-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W598230A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG2000-NH2 hydrochloride is a barrier permeation compound involved in the preparation of hybrid gels with adsorption and size exclusion chromatography (AdSEC) properties. m-PEG-NH2 helps AdSEC gels separate from complex biological mixtures such as blood, urine, sweat, and tears.
|
-
- HY-172283A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-BR2 is a PEG compound which composed of DSPE and a BR2. BR2 is a targeting peptide composed of 17 amino acids with the sequence RAGLQFPVGRLLRRLLR. It has the ability to assist cells to penetrate the membrane and can specifically target certain cells or tissues .
|
-
- HY-172283C
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-BR2 is a PEG compound which composed of DSPE and a BR2. BR2 is a targeting peptide composed of 17 amino acids with the sequence RAGLQFPVGRLLRRLLR. It has the ability to assist cells to penetrate the membrane and can specifically target certain cells or tissues .
|
-
- HY-172283
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-BR2 is a PEG compound which composed of DSPE and a BR2. BR2 is a targeting peptide composed of 17 amino acids with the sequence RAGLQFPVGRLLRRLLR. It has the ability to assist cells to penetrate the membrane and can specifically target certain cells or tissues .
|
-
- HY-172283B
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-BR2 is a PEG compound which composed of DSPE and a BR2. BR2 is a targeting peptide composed of 17 amino acids with the sequence RAGLQFPVGRLLRRLLR. It has the ability to assist cells to penetrate the membrane and can specifically target certain cells or tissues .
|
-
- HY-181017
-
|
|
Reactive Oxygen Species (ROS)
DNA/RNA Synthesis
PARP
Quinone Reductase
|
Cancer
|
|
Ola-NC-SS-PEG-Lap is a selective immunogenic cell death inducer. Ola-NC-SS-PEG-Lap exploits the synergistic interplay between an NQO1-bioactivated compound and a PARP inhibitor to selectively induce immunogenic cell death in tumor cells without harming normal cells. Ola-NC-SS-PEG-Lap induces ROS accumulation, increases DNA damage. Ola-NC-SS-PEG-Lap can be activated by GSH and release Ola, ultimately producing the synergistic antitumor effect with the Lap portion. Ola-NC-SS-PEG-Lap has anti-cancer activity against colon cancer .
|
-
- HY-W800658
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG6-NH-Boc is a click chemistry reagent with a DBCO group and a Boc-protected amine. The DBCO can undergo copper-free Click Chemistry reactions with azides. The Boc protecting group can be removed under acidic conditions. The hydrophilic PEG linker increases the water solubility of the compound.
|
-
- HY-160839
-
|
|
Fluorescent Dye
|
Others
|
|
SPB-PEG4-AAD (compound 6) is a BFPX probe. SPB-PEG4-AAD shows significant crosslinking of the Nkx2.5/DNA complex or p53/DNA complex while displaying little effect on the DNA alone .
|
-
- HY-172711A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG3400-R6H4 can be used for drug delivery .
|
-
- HY-172273B
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .
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-
- HY-172273A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .
|
-
- HY-172273
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .
|
-
- HY-172711
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG2000-R6H4 can be used for drug delivery .
|
-
- HY-172712
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3000-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG3000-R6H4 can be used for drug delivery .
|
-
- HY-151772
-
|
|
ADC Linker
|
Others
|
|
Methyltetrazine-PEG12-t-butyl ester is a monodisperse PEG compound. Methyltetrazine-PEG12-t-butyl ester is a click chemistry reagent containing a tetrazine group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-149416
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Mal-PEG8-Val-Ala-PAB-SB-743921 (Compound D7) is a Drug-Linker Conjugates for ADC. Mal-PEG8-Val-Ala-PAB-SB-743921 consists of KSP inhibitor SB-743921 (HY-14661) and a linker. Mal-PEG8-Val-Ala-PAB-SB-743921 can be used for synthesis of ADCs .
|
-
- HY-172710
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG1000-R6H4 can be used for drug delivery .
|
-
- HY-172273C
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .
|
-
- HY-147271
-
|
|
Drug-Linker Conjugates for ADC
Topoisomerase
|
Cancer
|
|
Mal-PEG8-Val-Ala-PAB-Exatecan (Compound 9b) is an antibody-drug conjugate linker (ADC linker) that binds to Nectin-4 polypeptides conjugated to chemotherapeutic agents. Mal-PEG8-Val-Ala-PAB-Exatecan can be used for cancer research .
|
-
- HY-160094
-
|
|
Ligands for Target Protein for PROTAC
|
Cancer
|
|
BCN-sulfonamide-PEG2-sulfonamide-N-bis ethanol (compound 71) is a Ligands for Target Protein for PROTAC that contains a sulfonamide linker to increase the solubility of the linker-conjugate. BCN-sulfonamide-PEG2-sulfonamide-N-bis ethanol can be used to synthesize PROTACs with antitumor activity .
|
-
- HY-176563
-
|
|
ADC Linker
|
Cancer
|
|
Di(4-morpholine-amide)-4-DTM-phenoxy(3,5-F)-PEG4-CH2COOH (compound BL) is a cleavable PEG-based ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-148153
-
|
|
Drug Derivative
|
Inflammation/Immunology
|
|
C6-Amide-(PEG)n-CH3 (n=310) is an active compound. C6-Amide-(PEG)n-CH3 is a small molecule moiety for PEGylation in Egaptivon pegol (HY-147079) that can be used for the research of platelet dysfunction disorders .
|
-
- HY-182095C
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG5000-CTP is a PEG compound which composed of DSPE and a Cardiac-targeting peptide CTP (HY-P4094). CTP molecules that specifically recognize cardiac tissue and is primarily used for targeted drug delivery. CTP effectively recognizes and binds to specific receptors on the surface of cardiac cells, thereby achieving precise localization of drug molecules. DSPE-PEG5000-CTP can be used for drug delivery .
|
-
- HY-182094C
-
|
|
Liposome
|
Metabolic Disease
|
|
DSPE-PEG5000-KTP is a PEG compound which composed of DSPE and a Kidney-targeting peptide KTP (HY-P11069). KTP can interact with specific proteins on the surface of renal tubular epithelial cells or exhibit higher affinity in the specific renal microenvironment, tending to aggregate or be internalized within the renal tubular epithelium. DSPE-PEG5000-KTP can actively guide carriers such as nanomedicines, liposomes, and microspheres to the kidney .
|
-
- HY-W190753
-
|
|
Biochemical Assay Reagents
|
Others
|
|
BocNH-PEG8-CH2CH2COONHS is a PEG linker containing an NHS ester and a Boc-protected amino group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The Boc group can be deprotected under mild acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-182094
-
|
|
Liposome
|
Metabolic Disease
|
|
DSPE-PEG1000-KTP is a PEG compound which composed of DSPE and a Kidney-targeting peptide KTP (HY-P11069). KTP can interact with specific proteins on the surface of renal tubular epithelial cells or exhibit higher affinity in the specific renal microenvironment, tending to aggregate or be internalized within the renal tubular epithelium. DSPE-PEG1000-KTP can actively guide carriers such as nanomedicines, liposomes, and microspheres to the kidney .
|
-
- HY-W403327
-
|
|
Biochemical Assay Reagents
|
Others
|
|
CbzNH-PEG4-CH2COOH is a PEG linker containing an carboxylic acid (CO2H) group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The terminal carboxylic acid is reactive with primary amine groups in the presence of activators (e.g. HATU) forming a stable amide bond. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
|
-
- HY-182095A
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG2000-CTP is a PEG compound which composed of DSPE and a Cardiac-targeting peptide CTP (HY-P4094). CTP molecules that specifically recognize cardiac tissue and is primarily used for targeted drug delivery. CTP effectively recognizes and binds to specific receptors on the surface of cardiac cells, thereby achieving precise localization of drug molecules. DSPE-PEG2000-CTP can be used for drug delivery .
|
-
- HY-W039178
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 191). Hydroxy-PEG4-(CH2)2-Boc is also a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-182094A
-
|
|
Liposome
|
Metabolic Disease
|
|
DSPE-PEG2000-KTP is a PEG compound which composed of DSPE and a Kidney-targeting peptide KTP (HY-P11069). KTP can interact with specific proteins on the surface of renal tubular epithelial cells or exhibit higher affinity in the specific renal microenvironment, tending to aggregate or be internalized within the renal tubular epithelium. DSPE-PEG2000-KTP can actively guide carriers such as nanomedicines, liposomes, and microspheres to the kidney .
|
-
- HY-182094B
-
|
|
Liposome
|
Metabolic Disease
|
|
DSPE-PEG3400-KTP is a PEG compound which composed of DSPE and a Kidney-targeting peptide KTP (HY-P11069). KTP can interact with specific proteins on the surface of renal tubular epithelial cells or exhibit higher affinity in the specific renal microenvironment, tending to aggregate or be internalized within the renal tubular epithelium. DSPE-PEG3400-KTP can actively guide carriers such as nanomedicines, liposomes, and microspheres to the kidney .
|
-
- HY-182095B
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG3400-CTP is a PEG compound which composed of DSPE and a Cardiac-targeting peptide CTP (HY-P4094). CTP molecules that specifically recognize cardiac tissue and is primarily used for targeted drug delivery. CTP effectively recognizes and binds to specific receptors on the surface of cardiac cells, thereby achieving precise localization of drug molecules. DSPE-PEG3400-CTP can be used for drug delivery .
|
-
- HY-42488
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196) . Hydroxy-PEG2-(CH2)2-Boc is also a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-W348348
-
|
|
Biochemical Assay Reagents
|
Others
|
|
CbzNH-PEG3-CH2CH2NH2 is a PEG linker containing an amine group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
|
-
- HY-W067061
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196) . Hydroxy-PEG2-(CH2)2-Boc is also a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-182095
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG1000-CTP is a PEG compound which composed of DSPE and a Cardiac-targeting peptide CTP (HY-P4094). CTP molecules that specifically recognize cardiac tissue and is primarily used for targeted drug delivery. CTP effectively recognizes and binds to specific receptors on the surface of cardiac cells, thereby achieving precise localization of drug molecules. DSPE-PEG1000-CTP can be used for drug delivery .
|
-
- HY-151833
-
|
|
ADC Linker
|
Others
|
|
Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent containing an azide group. Methyltetrazine-amido-N-bis(PEG4-acid) is a PEG derivative that contains a methyltetrazine group and two acid groups. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. PEG linker increases the water solubility of the compound. Reagent grade, for research use only . Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-W591992
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PEG17 is a polymer consisiting of repeating ethylene glycol subunits and terminal hydroxyl groups. The ethylene glycol units increase the water solubility of hydrophobic compounds, allowing for them to be more compatible in aqueous settings. The terminal hydroxyl groups can react to further derivatize the compound.
|
-
- HY-180568
-
|
|
ADC Linker
|
Cancer
|
|
Bromoacetamide-PEG4-DBCO (Compound bromoacetamido-dPEG ®4-amido-DBCO) is a ADC linker and can be used for synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130652
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Pomalidomide 4'-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a linker. Pomalidomide 4'-PEG3-azide can be used for the synthesis of iRucaparib-TP3 (Compound 3). iRucaparib-TP3 is a highly efficient PARP1?degrader based on Rucaparib by using the PROTAC approach . Pomalidomide 4'-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-182096C
-
|
|
Liposome
|
Neurological Disease
|
|
DSPE-PEG5000-MG1 is a PEG compound which composed of DSPE and a MG1 peptide (HY-P11315). MG1 peptide is a M1 Microglia-targeting peptide. MG1 peptide can conjugate to anoparticles, crossing the BBB to precisely M1 microglia recognition and achieving controlled release and specific accumulation of drugs through intelligent molecular switching. DSPE-PEG5000-KTP can be used for drug delivery .
|
-
- HY-129772
-
|
|
PROTAC Linkers
|
Cancer
|
|
Phthalimide-PEG3-C2-OTs (Compound 5) is a PROTAC linker, which refers to the PEGs composition. Phthalimide-PEG3-C2-OTs can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins .
|
-
- HY-182096A
-
|
|
Liposome
|
Neurological Disease
|
|
DSPE-PEG2000-MG1 is a PEG compound which composed of DSPE and a MG1 peptide (HY-P11315). MG1 peptide is a M1 Microglia-targeting peptide. MG1 peptide can conjugate to anoparticles, crossing the BBB to precisely M1 microglia recognition and achieving controlled release and specific accumulation of drugs through intelligent molecular switching. DSPE-PEG2000-KTP can be used for drug delivery .
|
-
- HY-182096B
-
|
|
Liposome
|
Neurological Disease
|
|
DSPE-PEG3400-MG1 is a PEG compound which composed of DSPE and a MG1 peptide (HY-P11315). MG1 peptide is a M1 Microglia-targeting peptide. MG1 peptide can conjugate to anoparticles, crossing the BBB to precisely M1 microglia recognition and achieving controlled release and specific accumulation of drugs through intelligent molecular switching. DSPE-PEG3400-KTP can be used for drug delivery .
|
-
- HY-177953
-
|
|
Drug-Linker Conjugates for ADC
c-Met/HGFR
|
Cancer
|
|
Mal-PEG2-Val-Arg-PABC-OMe-Eribulin (Compound L-1) is a drug-linker conjugate composed of O-Me Eribulin (HY-159576) and the linker Mal-PEG2-Val-Cit-PAB-OH (HY-130222). Mal-PEG2-Val-Arg-PABC-OMe-Eribulin can be used to synthesize anti-HER3/MET antibody-drug conjugates (ADCs) .
|
-
- HY-182096
-
|
|
Liposome
|
Neurological Disease
|
|
DSPE-PEG1000-MG1 is a PEG compound which composed of DSPE and a MG1 peptide (HY-P11315). MG1 peptide is a M1 Microglia-targeting peptide. MG1 peptide can conjugate to anoparticles, crossing the BBB to precisely M1 microglia recognition and achieving controlled release and specific accumulation of drugs through intelligent molecular switching. DSPE-PEG1000-KTP can be used for drug delivery .
|
-
- HY-W800760
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
(S, R, S)-AHPC-PEG6-Tos is a combination of a von Hippel-Lindau (VHL)-recruiting ligand and PEGylated crosslinker with a tosyl group. The tosyl group is a good leaving group for nucleophilic substitution reactions. (S, R, S)-AHPC-PEG2-Tos is useful for synthesis of PROTAC compounds and molecules for targeted protein degradation.
|
-
- HY-172271A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-LyP-1 is a PEG compound which composed of DSPE and a nine residue peptide (LyP-1) (HY-P2526). LyP-1 is a cyclic 9-amino-acids tumor homing peptide and selectively bind to p32 receptors overexpressed in various tumor-associated cells .
|
-
- HY-172271B
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3000-LyP-1 is a PEG compound which composed of DSPE and a nine residue peptide (LyP-1) (HY-P2526). LyP-1 is a cyclic 9-amino-acids tumor homing peptide and selectively bind to p32 receptors overexpressed in various tumor-associated cells .
|
-
- HY-158199
-
|
|
ADC Linker
|
Cancer
|
|
BCN-HS-PEG2-bis(PNP) (Compound 62) is a p-nitrophenyl-containing ADC linker that can be used to further couple ADC cytotoxins with peptide linkers. BCN-HS-PEG2-bis(PNP) can conjugate with vc-PABC-MMAE (HY-15162) to form Drug-Linker Conjugates for ADC .
|
-
- HY-148459
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
ATAC21, a linker-immune-stimulatory compound that can be formed by conjugating a noncleavable maleimide-PEG4 linker containing a succinimide group with an immune- stimulatory compound. ATAC21 can be combined with SBT-040 (anti-CD40 antibody) to form a conjugate .
|
-
- HY-178145
-
|
|
Drug-Linker Conjugates for ADC
Topoisomerase
|
Cancer
|
|
Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan (compound 12) is a Drug-Linker Conjugate for ADC. Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan contains the ADC linker (Mc-Lys(PEG12)-Cap-Ala-Ala-PABC) (HY-178146) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan can be used for the development of ADC targeting HER2-positive breast cancer .
|
-
- HY-132161
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
MP-PEG4-Val-Lys-Gly-7-MAD-MDCPT is a Camptothecin-linker compound extracted from patent WO2019195665A1, example 4-1. MP-PEG4-Val-Lys-Gly-7-MAD-MDCPT is a agent-linker conjugate for antibody-drug conjugate (ADC) .
|
-
- HY-172714A
-
|
|
Liposome
|
Infection
|
|
DSPE-PEG3400-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
|
-
- HY-W591402
-
|
|
ADC Linker
|
Cancer
|
|
3,4-Dibromo-Mal-PEG4-acid is a site specific ADC linker with a dibromomaleimide group and an acid group. The dibromomaleimide group allows for two points of substitution due to the two bromine atoms. The carboxylic acid can react with primary amines in the presence of EDC and HATU to form a stable amide bond. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.
|
-
- HY-172714
-
|
|
Liposome
|
Infection
|
|
DSPE-PEG2000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
|
-
- HY-172713
-
|
|
Liposome
|
Infection
|
|
DSPE-PEG1000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
|
-
- HY-147192
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
(S,R,S)-AHPC-O-PEG1-propargyl (Compound 10b) is an E3 ligand for the synthesis of PROTAC . (S,R,S)-AHPC-O-PEG1-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W591332
-
|
|
Liposome
|
Cancer
|
|
mPEG2000-DMPE is a PEGylated 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE) compound with a methyl group at the other end of the PEG chain. The PEG polymer exhibits amphiphatic behavior and helps to form stable micelles in an aqueous solution. It can be used to prepare nanoparticles or liposomes for targeted drug delivery applications.
|
-
- HY-130853
-
|
|
E3 Ligase Ligand-Linker Conjugates
Autophagy
Apoptosis
|
Cancer
|
|
Thalidomide-NH-PEG2-C2-NH-Boc is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the?Thalidomide?based cereblon ligand and a PEG linker used for dBRD9 (compound 6) synthesis. dBRD9 is a selective BRD9 probe PROTAC degrader for the study of BAF complex biology .
|
-
- HY-172715
-
|
|
Liposome
|
Infection
|
|
DSPE-PEG5000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
|
-
- HY-179560
-
|
|
Polo-like Kinase (PLK)
MDM-2/p53
|
Cancer
|
|
PMV6-PEG4-BI2536 is a p53-Y220C-PLK1 dual-functional compound, composed of a high-affinity p53-Y220C mutant binder (Kd ≈ 2.5 nM) and a potent PLK1 kinase inhibitor (IC50 = 0.83 nM). PMV6-PEG4-BI2536 triggers TP53 Y220C cell G2/M arrest and apoptosis through PLK1 mislocalization and kinase inhibition, independent of p53 transcriptional reactivation. PMV6-PEG4-BI2536 can be used for the study of TP53 mutant cancers .
|
-
- HY-W909319
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-(t-Butyloxycarbonyl-PEG4)isoindoline-1,3-dione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-174365H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-NPC (MW 20000) is an important PEG derivative whose reactive groups can be used to modify proteins, peptides or any other compounds with available amino groups at lysine residues or N-terminus .
|
-
- HY-W395122
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG1-PNP-carbonate is a amine-reactive compound. PNP is a good leaving group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-140025
-
|
|
ADC Linker
|
Cancer
|
|
Propargyl-PEG4-CH2CO2-NHS (compound P-7) is a PEG derivative containing a propargyl group and an NHS group. Propargyl-PEG4-CH2CO2-NHS is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG4-CH2CO2-NHS is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
|
-
- HY-159701A
-
|
|
Drug Intermediate
|
Others
|
|
DBCO-PEG2000-alendronic acid sodium is a PEG linker conjugated with alendronic acid (HY-B0631) and DBCO groups. Alendronic acid possesses bone-targeting properties, enabling strong chelation with calcium ions in bone and hydroxyapatite, and exhibits high specific adsorption on mineralized tissues such as bones and teeth. This compound can be applied to construct bone-targeted drug delivery systems and bone tissue imaging probes.
|
-
- HY-W591332A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG1000-DMPE is a PEGylated 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE) compound with a methyl group at the?other?end of the PEG chain. The PEG polymer exhibits amphiphatic behavior and helps to form stable micelles in an aqueous solution. It can be used to prepare nanoparticles or liposomes for targeted drug delivery applications .
|
-
- HY-174365D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG10000-NPC is an important PEG derivative whose reactive groups can be used to modify proteins, peptides or any other compounds with available amino groups at lysine residues or N-terminus .
|
-
- HY-174365B
-
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Biochemical Assay Reagents
|
Others
|
|
mPEG3400-NPC is an important PEG derivative whose reactive groups can be used to modify proteins, peptides or any other compounds with available amino groups at lysine residues or N-terminus .
|
-
- HY-174365E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG40000-NPC is an important PEG derivative whose reactive groups can be used to modify proteins, peptides or any other compounds with available amino groups at lysine residues or N-terminus .
|
-
- HY-174365
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG1000-NPC is an important PEG derivative whose reactive groups can be used to modify proteins, peptides or any other compounds with available amino groups at lysine residues or N-terminus .
|
-
- HY-174365C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG5000-NPC is an important PEG derivative whose reactive groups can be used to modify proteins, peptides or any other compounds with available amino groups at lysine residues or N-terminus .
|
-
- HY-174365A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG2000-NPC is an important PEG derivative whose reactive groups can be used to modify proteins, peptides or any other compounds with available amino groups at lysine residues or N-terminus .
|
-
- HY-176202
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
TLR7/8 agonist 12-PAB-(PEG4-Me)-Cit-Val-PEG2-amide-C2-MC (compound LIV1-IMC (12) linker-payload) is a linker-payload conjugate, used in the synthesis of antibody-drug conjugates (ADCs).TLR7/8 agonist 12-PAB-(PEG4-Me)-Cit-Val-PEG2-amide-C2-MC contains TLR7/8 agonist (HY-170770) (ADC payload) and a linker (HY-176478) .
|
-
- HY-139018
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
TLR7/8 agonist 4 hydroxy-PEG10-acid (compound 9) is a drug-linker conjugates for ADC with potent antitumor activity by using TLR7/8 agonist 4 (HY-139018; a TLR7/8 agonist), linked via the non-cleavable ADC linker hydroxy-PEG10-acid (HY-133307) .
|
-
- HY-139018A
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugates for ADC with potent antitumor activity by using TLR7/8 agonist 4 (HY-139018; a TLR7/8 agonist), linked via the non-cleavable ADC linker hydroxy-PEG10-acid (HY-133307) .
|
-
- HY-W615173
-
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|
Biochemical Assay Reagents
|
Others
|
|
NHS ester-C2-NHCO-C2-NHS is a heterobifunctional PEG linker, featuring a terminal NHS ester that can be used to label amine compounds and maleimide group for reactions with thiol groups.
|
-
- HY-176947
-
|
|
Drug Intermediate
|
Cancer
|
|
Demethyl-sapanisertib-C2-amide-PEG7-C2-N3 (Compound 10c) is an azide group linker used for coupling, which can be employed in the synthesis of "Rapa-Link" compounds, such as M-1111 (HY-176948), an mTOR inhibitor .
|
-
- HY-43192
-
|
2-(2-((6-Chlorohexyl)oxy)ethoxy)ethan-1-ol
|
Drug Intermediate
|
Others
|
|
Ho-peg2-(ch2)6-Cl (2-(2-((6-Chlorohexyl)oxy)ethoxy)ethan-1-ol) is a drug intermediate for synthesis of various active compounds.
|
-
- HY-160247
-
|
|
Drug-Linker Conjugates for ADC
|
Others
|
|
Boc-Lys-PEG8-N-bis(D-glucose) (compound 89-5) is a drug linker that can be used in the synthesis of antibody-drug conjugates (ADCs) extracted from patent WO2023280227A2 .
|
-
- HY-W190920
-
|
|
Biochemical Assay Reagents
|
Others
|
|
t-Butoxycarbonyl-PEG2-NHS ester has a t-Boc protecting group and an NHS ester moiety. The t-butyl group can be deprotected under acidic conditions. NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
|
-
- HY-171814
-
|
|
Drug-Linker Conjugates for ADC
N-myristoyltransferase
|
Cancer
|
|
Mal-PEG2-amide-C2-amide-Phenyl(β-D-glucuronide)-NMT-IN-7 (Compound DC-2) is a drug-linker conjugate for ADC. Mal-PEG2-amide-C2-amide-Phenyl(β-D-glucuronide)-NMT-IN-7 consists of a NMT inhibitor (HY-160945) and a stable and cleavable linker (Mal-PEG2-amide-C2-amide-Phenyl(β-D-glucuronide)). Mal-PEG2-amide-C2-amide-Phenyl(β-D-glucuronide)-NMT-IN-7 can be used for synthesis of ADCs .
|
-
- HY-147231
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
SG3400 delate (Mal-amido-PEG8) (compound 21) is an intermediate for the synthesis of ADC molecules. SG3400 delete is an effective toxin molecule with anticancer activity. SG3400 delete can be used in cancer research .
|
-
- HY-155791
-
|
|
ADC Linker
|
Cancer
|
|
SMCC-NH-CH2-triazole-PEG8-oxydiacetamide-Lys(MTT)-PAB (Page 7, Compound C) is an ADC linker that can be used for the synthesis of antibody-conjugated active molecules (ADC) .
|
-
- HY-172271
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-Mal-Cys-CGNKRTRGC (Disulfide bridge: Cys2-Cys10) is a PEG compound which composed of DSPE and a nine residue peptide (LyP-1) (HY-P2526). LyP-1 is a cyclic 9-amino-acids tumor homing peptide and selectively bind to p32 receptors overexpressed in various tumor-associated cells .
|
-
- HY-157006A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TCO-PEG3-NH2 is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. The amino group of TCO-PEG3-NH2 can react with compounds containing carboxyl, ester, or other reactive groups to form stable amide bonds, enabling site-specific conjugation or modification of biomolecules.
|
-
- HY-160497
-
|
|
PROTAC-Linker Conjugates for PAC
|
Cancer
|
|
MC-(β-Ala)-PABC-(β-D-GlcUA)-amide-PEG1-CH2-CC-885 (Compound Ie) is a neodegrader conjugate, can be used in the synthesis of antibody neoDegrader conjugate (AnDC) .
|
-
- HY-143208
-
|
|
DNA/RNA Synthesis
|
Cancer
|
|
HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt has inhibitory activity against pre-miR-21 RNA. HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt has the potential for the research of neoplastic disease such as cancer and especially cancers expressing miR-21 (extracted from patent WO2021087084A1, compound 25) .
|
-
- HY-186048
-
|
|
Drug-Linker Conjugates for ADC
|
Infection
|
|
MC-VC-PAB-Daptomycin (Compound 54) is the linker-payload of an antibody-drug conjugate (ADC). β-Glucuronide-dPBD-PEG6-NH2 is composed of Daptomycin (HY-13631), a lipopeptide antibiotic, and the linker .
|
-
- HY-W096068
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Propargyl-PEG5-Ms represents a bifunctional linker possessing a proparygyl group reactive towards azides in copper (I) click chemistry to form stable triazoles with the target compound as well as a mesyl group which is a good leaving group for nucleophilic reactions.
|
-
- HY-148346A
-
|
|
Drug-Linker Conjugates for ADC
STING
|
Cancer
|
|
STING agonist-20-Ala-amide-PEG2-C2-NH2 (Compound 30b) TFA is an active scaffold comprising a stimulator of interferon genes (STING). STING agonist-20-Ala-amide-PEG2-C2-NH2 TFA can be used to synthesize immune-stimulating antibody conjugate (ISAC). STING agonist-20-Ala-amide-PEG2-C2-NH2 TFA can be used for the research of cancer .
|
-
- HY-161250
-
|
|
PROTACs
|
Cancer
|
|
Pomalidomide-NH-PEG6-amide-C2-CPI-1612 (compound 22 (dCE-1)) is a CBP/EP300 degrader, which contains a CRBN ligands Pomalidomide, a 24-atom linker with 6 PEG units and a HAT inhibitor CPI-1612. Pomalidomide-NH-PEG6-amide-C2-CPI-1612 exhibits antiproliferative effects in cells multiple myeloma cells LP1 (with a DC50 of 1.2 μM), MM1S and various cancer cell lines, especially the leukemia cells .
|
-
- HY-W800649
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Aminooxy-PEG2-amine hydrochloride (compound L3) is an aqueous soluble crosslinker. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond, if a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term .
|
-
- HY-182098B
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-GALA is a PEG compound which composed of DSPE and a lung endothelium-targeting peptide GALA (HY-P5423). GALA is a pH-responsive amphipathic peptide consisting of 30 amino acids, which acts as a lung endothelium-targeting ligand. GALA undergoes a conformational transition from random coil to α-helix in an acidic environment at pH 5.0, thereby inducing endosomal membrane destabilization and fusion. GALA-modified liposomes traverse lung endothelial cells via clathrin-dependent endocytosis and transcytosis, and specifically accumulate in the lungs after intravenous injection. DSPE-PEG3400-GALA can be used for drug delivery .
|
-
- HY-130984
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG1-CH2COO-Cl (compound 43a) is an alkyl/ether-based PROTAC linker. Azido-PEG1-CH2COO-Cl can be used in the synthesis of PROTAC BRD4 Degrader-1 (HY-133131) . Azido-PEG1-CH2COO-Cl is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-182098C
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-GALA is a PEG compound which composed of DSPE and a lung endothelium-targeting peptide GALA (HY-P5423). GALA is a pH-responsive amphipathic peptide consisting of 30 amino acids, which acts as a lung endothelium-targeting ligand. GALA undergoes a conformational transition from random coil to α-helix in an acidic environment at pH 5.0, thereby inducing endosomal membrane destabilization and fusion. GALA-modified liposomes traverse lung endothelial cells via clathrin-dependent endocytosis and transcytosis, and specifically accumulate in the lungs after intravenous injection. DSPE-PEG5000-GALA can be used for drug delivery .
|
-
- HY-182098
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-GALA is a PEG compound which composed of DSPE and a lung endothelium-targeting peptide GALA (HY-P5423). GALA is a pH-responsive amphipathic peptide consisting of 30 amino acids, which acts as a lung endothelium-targeting ligand. GALA undergoes a conformational transition from random coil to α-helix in an acidic environment at pH 5.0, thereby inducing endosomal membrane destabilization and fusion. GALA-modified liposomes traverse lung endothelial cells via clathrin-dependent endocytosis and transcytosis, and specifically accumulate in the lungs after intravenous injection. DSPE-PEG1000-GALA can be used for drug delivery .
|
-
- HY-182098A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-GALA is a PEG compound which composed of DSPE and a lung endothelium-targeting peptide GALA (HY-P5423). GALA is a pH-responsive amphipathic peptide consisting of 30 amino acids, which acts as a lung endothelium-targeting ligand. GALA undergoes a conformational transition from random coil to α-helix in an acidic environment at pH 5.0, thereby inducing endosomal membrane destabilization and fusion. GALA-modified liposomes traverse lung endothelial cells via clathrin-dependent endocytosis and transcytosis, and specifically accumulate in the lungs after intravenous injection. DSPE-PEG2000-GALA can be used for drug delivery .
|
-
- HY-W591308
-
|
|
Biochemical Assay Reagents
|
Others
|
|
3-[2-(3-hydroxypropoxy)ethoxy]propan-1-ol is a linker consisting of two terminal hydroxyl groups. The partial PEG chain increases the water solubility of a compound in aqueous media. The hydroxyl groups enables further derivatization or replacement with other reactive functional groups.
|
-
![3-[2-(3-Hydroxypropoxy)ethoxy]propan-1-ol](//file.medchemexpress.com/product_pic/hy-w591308.gif)
- HY-145448
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
MC-VC-PABC-amide-PEG1-CH2-CC-885 (compound I-1) is a neoDegrader-Linker conjugate, consists of the GSPT1 degrader/molecular glue CC-885 (HY-101488) and a linker. MC-VC-PABC-amide-PEG1-CH2-CC-885 can be conjugated to the antibody DAR3.7 that specifically targets CD56 to synthesize Antibody-Drug Conjugates (ADCs) .
|
-
- HY-W800718
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Methyltetrazine-amido-Tri-(acid-PEG1-ethoxymethyl)-methane is a click chemistry PEG reagent which contains three carboxylic acid groups and a methyltetrazine group. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
|
-
- HY-172723
-
|
|
Liposome
Transferrin Receptor
|
Neurological Disease
Cancer
|
|
DSPE-PEG2000-T7 is a PEGylated compound composed of DSPE and peptideT7. T7 (HAIYPRH) specifically binds to TfR. DSPE-PEG2000-T7 can be used to prepare T7-modified liposomes, where liposomes modified with both T7 and DA7R peptides can effectively co-deliver Doxorubicin (HY-15142A) and Vincristine (HY-N0488A) to gliomas. DSPE-PEG2000-T7 can also be used to prepare nanomodulators that mediate the co-delivery of tyrosine hydroxylase mRNA and interferon gene stimulator antagonists for synergistic intervention in Parkinson's disease .
|
-
- HY-W440681
-
|
|
Liposome
|
Others
|
|
C13-112-tri-tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tri-tail can be formulated into a lipid nanoparticle (LNP).
|
-
- HY-W440683
-
|
|
Liposome
|
Others
|
|
C13-112-tetra-tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tetra-tail can be formulated into a lipid nanoparticle (LNP).
|
-
- HY-126192
-
|
PiB; 6-OH-BTA-1
|
Amyloid-β
|
Neurological Disease
|
|
Pittsburgh Compound B (PiB) is a blood-brain barrier-permeable, specific Aβ deposition PET tracer that binds to Aβ(1-40) fibrils with a Ki value of 678.4 nM. Through click chemical modification (a clickable Pittsburgh Compound B derivative is prepared by introducing a PEG3 linker and an alkynyl group at the 6-hydroxy site of Pittsburgh Compound B, followed by covalent conjugation with azide-labeled fluorescent dyes or affinity tags via copper-catalyzed azide-alkyne cycloaddition (CuAAC)), Pittsburgh Compound B and its conjugates can be used for fluorescence imaging, ultrastructural studies, and enrichment and characterization of Aβ complexes. Pittsburgh Compound B is applicable to Alzheimer's disease research .
|
-
- HY-W800650
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Aminooxy-PEG1-amine is a chemical reagent containing an aminooxy group and a primary amine. The aminooxy group is reactive with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive withactivated NHS esters, or carboxylic acid in the presence of coupling reagent EDC. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term.
|
-
- HY-182813
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
MC-amide-C2-amide-(β-D-GlcUA)-amide-PEG1-CH2-CC-885 is a Drug-Linker Conjugates for ADC composed of CC-885 (HY-101488) and a linker. MC-amide-C2-amide-(β-D-GlcUA)-amide-PEG1-CH2-CC-885 conjugates with GemtUZUmab (HY-P99971) to synthesize an ADC (Compound ADC-2). ADC-2 exhibits anti-tumor activity in a leukemia MV-4-11 xenograft model .
|
-
- HY-181500
-
|
|
Target Protein Ligand-Linker Conjugates
FKBP
|
Cancer
|
|
AP1867-NH-PEG3-acid (Compound S15) is a Target Protein Ligand-Linker Conjugate that contains the FKBP12 F36V ligand AP1867 (HY-114434) and a PROTAC linker, and recruits E3 ligase. JQ-1-Azidopropylamine is available for the synthesis of PROTAC RAFKBP12 (HY-181498) .
|
-
- HY-130715
-
|
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl 11-aminoundecanoate (compound 6b) is a PROTAC linker, which refers to the PEG composition. tert-Butyl 11-aminoundecanoate can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins .
|
-
- HY-176863
-
|
|
Androgen Receptor
|
Neurological Disease
|
|
Di(5-(methylsulfonyl)-1,3,4-oxadiazol-2-yl)-benzene-amide-PEG4-ester-2,3,5,6-F-Ph (Compound L-1026) is a linker that connects Androgen Receptor (AR) RNAi agent to targeting ligands (such as antibodies). The conjugation can inhibit AR gene expression and reduce AR activity. Di(5-(methylsulfonyl)-1,3,4-oxadiazol-2-yl)-benzene-amide-PEG4-ester-2,3,5,6-F-Ph can be used for spinal and bulbar muscular atrophy (SBMA) research .
|
-
- HY-172771
-
|
|
PI3K
DNA-PK
P-glycoprotein
|
Cancer
|
|
Multi-target kinase inhibitor 4 (Compound 2) is a PI3K/DNA-PK inhibitor and potent chemosensitizer that can increase the amount of DNA double strand breaks induced by Doxorubicin (HY-15142A). Multi-target kinase inhibitor 4, is an efficient inhibitor of multidrug resistance (MDR) that exhibits inhibitory activity toward P-glycoprotein-mediated drug efflux. Multi-target kinase inhibitor 4 can be loaded into PEG-coated LNPs .
|
-
- HY-W800721
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Methyltetrazine-amido-bis-(carboxyethoxymethyl)-methane is a click chemistry PEG reagent which contains three carboxylic acid groups and a methyltetrazine group. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
|
-
- HY-174867
-
|
|
PROTACs
Ferroptosis
|
Cancer
|
|
AY-4 (Compound AY-4) is an efficient PROTAC degrader targeting FTH1 (Kd = 3.17 nM). AY-4 effectively upregulates the levels of ferrous (Fe 2+) and ferric (Fe 3+) ions in cells. AY-4 is a potential anticancer candidate compound that regulates iron homeostasis through ferritin degradation and enhances the efficacy of existing drugs. AY-4 can effectively reduce the level of FTH1 in breast cancer cells (Pink: FTH1 ligand AY-2 (HY-174871); Blue: E3 ligand Pomalidomide (HY-10984); Black: Linker, Pomalidomide-PEG3-acid (HY-174872)) .
|
-
- HY-P11455
-
|
|
Liposome
|
Others
|
|
Lipopeptide CPE4 is a PEG-modified peptide E4 [(EIAALEK) 4]. Lipopeptide CPE4 is capable of coiled-coil formation when attached to liposomes. Lipopeptide CPE4 triggers membrane fusion between liposomes and living cells with concomitant efficient cytosolic delivery of a variety of compounds such as fluorescent dyes Propidium Iodide (PI) (HY-D0815) and TO-PRO-3 iodide (HY-117070), and Doxorubicin (DOX) (HY-15142A). Lipopeptide CPE4 can be used for drug delivery research .
|
-
- HY-P11455A
-
|
|
Liposome
|
Others
|
|
Lipopeptide CPE4 TFA is a PEG-modified peptide E4 [(EIAALEK) 4]. Lipopeptide CPE4 TFA is capable of coiled-coil formation when attached to liposomes. Lipopeptide CPE4 TFA triggers membrane fusion between liposomes and living cells with concomitant efficient cytosolic delivery of a variety of compounds such as fluorescent dyes Propidium Iodide (PI) (HY-D0815) and TO-PRO-3 iodide (HY-117070), and Doxorubicin (DOX) (HY-15142A). Lipopeptide CPE4 TFA can be used for drug delivery research .
|
-
- HY-149845
-
|
|
PROTACs
GSK-3
|
Neurological Disease
|
|
PROTAC GSK-3β Degrader-1 (compound 1) is a degrader targets GSK-3β degradation with an IC50 value of 833 nM. PROTAC GSK-3β Degrader-1 contains SB-216763 (a GSK-3β inhibitor), a PEG linker and a CRBN (E3 ligase liand). PROTAC GSK-3β Degrader-1 reduces the neurotoxicity induced by Aβ25-35 peptide and CuSO4. PROTAC GSK-3β Degrader-1 can be used to research in Alzheimer's disease .
|
-
- HY-131203
-
|
|
PROTACs
Epigenetic Reader Domain
Apoptosis
c-Myc
Caspase
|
Cancer
|
|
PROTAC BRD4 Degrader-6 (compound 32a) is a potent small-molecule BRD4PROTAC degrader with IC50 value of 2.7 nM for BRD4 BD1. PROTAC BRD4 Degrader-6 potently degrades BRD4 protein and inhibits the expression of c-Myc. PROTAC BRD4 Degrader-6 inhibits the proliferation of pancreatic cancer cell line BxPC3 and induces apoptosis. PROTAC BRD4 Degrader-6 can be used for human pancreatic cancer research (Pink:
Mivebresib (HY-100015); Black: linker, Azido-PEG1-CH2CO2H (HY-108369); Blue: Lenalidomide (HY-A0003)) .
|
-
- HY-173703
-
|
|
Topoisomerase
Drug Intermediate
|
Cancer
|
|
β-Glu-PAB(CH2NH2)-Exatecan (Compound 9a) is a topoisomerase I inhibitor. β-Glu-PAB(CH2NH2)-Exatecan binds to the topoisomerase I-DNA complex to prevent DNA strand reconnection, thereby inducing DNA breakage and cell apoptosis. β-Glu-PAB(CH2NH2)-Exatecan can be specifically cleaved by β-glucuronidase highly expressed in the tumor microenvironment to release Exatecan for cytotoxic effect. β-Glu-PAB(CH2NH2)-Exatecan is also an intermediate of Mal((3S,3aR,6S,6aR) -hexahydrofuro [3, 2-B]furan-3,6-diamine-PEG12)-β -Glu-Pab-Exatecan. β-Glu-PAB(CH2NH2)-Exatecan is promising for research of cancers .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D1312
-
|
|
Fluorescent Dye
|
|
Pyrene azide 2 is a compound derived from pyreneacetic acid, connecting a fluorescent pyrene molecule by a PEG2 linker. The PEG units improve the water solubility of the compound.
|
-
- HY-D2514
-
|
|
Fluorescent Dye
|
|
Cy3-PEG1000-DSPE is a compound for the labeling and visualization of nanoparticles or other materials. Cy3-PEG1000-DSPE has a variety of applications including drug delivery, cellular imaging, tracing of bioprocesses, and the study of interactions at the molecular level.
|
-
- HY-D2518
-
|
|
Fluorescent Dye
|
|
Cy3-PEG10000-DSPE is a compound for the labeling and visualization of nanoparticles or other materials. Cy3-PEG10000-DSPE has a variety of applications including drug delivery, cellular imaging, tracing of bioprocesses, and the study of interactions at the molecular level.
|
| Cat. No. |
Product Name |
Type |
-
- HY-Y0873Q
-
|
Polyethylene glycol 20000
|
Biochemical Assay Reagents
|
|
PEG20000 (Polyethylene glycol 20000) can be used as a solubilizer. PEG20000 is a kind of biological materials or organic compounds that are widely used in life science research, can be degraded by bacteria .
|
-
- HY-Y0873P
-
|
Polyethylene glycol 10000
|
Biochemical Assay Reagents
|
|
PEG10000 (Polyethylene glycol 10000) can be used as a solubilizer. PEG10000 is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-177203
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-APWHLSSQYSRT is a PEG compound which composed of DSPE and 12-amino acid cardiac targeting peptide (APWHLSSQYSRT). DSPE-PEG2000-APWHLSSQYSRT can be used for drug delivery .
|
-
- HY-172277A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG2000-R9 can be used for drug delivery .
|
-
- HY-172354
-
|
|
Biochemical Assay Reagents
|
|
Acrylate-PEG2000-NHS is a photosensitive PEG compound that can be cross-linked when exposed to ultraviolet light and is used to synthesize PEG hydrogels .
|
-
- HY-174926A
-
|
|
Biochemical Assay Reagents
|
|
8-Arm PEG20000-COOH is a compound composed of PEG units and carboxyl (-COOH) groups, which can be used for drug delivery .
|
-
- HY-172279
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-TAT is a PEG compound which composed of DSPE and a cell-penetrating peptide (TAT) (HY-P0281). DSPE-PEG1000-TAT can be used for drug delivery .
|
-
- HY-172279C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-TAT is a PEG compound which composed of DSPE and a cell-penetrating peptide (TAT) (HY-P0281). DSPE-PEG3400-TAT can be used for drug delivery .
|
-
- HY-172354A
-
|
|
Biochemical Assay Reagents
|
|
Acrylate-PEG3500-NHS is a photosensitive PEG compound that can be cross-linked when exposed to ultraviolet light and is used to synthesize PEG hydrogels .
|
-
- HY-168940H
-
|
|
Biochemical Assay Reagents
|
|
NH2-PEG5000-COOH is a compound composed of NH2, PEG units and carboxyl (-COOH) groups, which can be used for drug delivery .
|
-
- HY-172687
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). DSPE-PEG2000-CSTSMLKAC can be used for drug delivery DSPE-PEG2000-CSTSMLKAC enables targeted delivery of associated nanoliposomes to ischemic myocardial cells .
|
-
- HY-172691
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .
|
-
- HY-172690
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .
|
-
- HY-168940D
-
|
|
Biochemical Assay Reagents
|
|
NH2-PEG400-COOH is a compound composed of NH2, PEG units and carboxyl (-COOH) groups, which can be used for drug delivery .
|
-
- HY-172278A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG2000-CGKRK can be used for drug delivery .
|
-
- HY-W1048533H
-
|
Biotin-PEG1000-Thiol
|
Biochemical Assay Reagents
|
|
Biotin-PEG1000-SH (Biotin-PEG1000-Thiol) is a biotin PEG polymer containing a thiol (-SH). Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
-
- HY-172279B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-TAT is a PEG compound which composed of DSPE and a cell-penetrating peptide (TAT) (HY-P0281). DSPE-PEG5000-TAT can be used for drug delivery .
|
-
- HY-172276A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG2000-R8 can be used for drug delivery .
|
-
- HY-W1048669B
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG10000-DMG is a compound composed of biotin, PEG, and myristoyl-sn-glycerol, used for drug delivery. Biotin forms a stable non-covalent bond with streptavidin.
|
-
- HY-116027A
-
|
Biotin-PEG10-COOH
|
Biochemical Assay Reagents
|
|
Biotin-PEG10-acid (Biotin-PEG10-COOH) is a biotin-PEG compound containing a carboxyl group (-COOH) that can be used to react with an amine group (NH2) to form a stable amide bond. Biotin-PEG10-acid can be used for protein labeling and drug delivery research .
|
-
- HY-172354B
-
|
|
Biochemical Assay Reagents
|
|
Acrylate-PEG5000-NHS is a photosensitive PEG compound that can be cross-linked when exposed to ultraviolet light and is used to synthesize PEG hydrogels .
|
-
- HY-168940I
-
|
|
Biochemical Assay Reagents
|
|
NH2-PEG20000-COOH is a compound composed of NH2, PEG units and carboxyl (-COOH) groups, which can be used for drug delivery .
|
-
- HY-172274A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-APRPG is a PEG compound which composed of DSPE and a APRPG peptide. DSPE-PEG2000-APRPG can be used for drug delivery .
|
-
- HY-172278C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG3400-CGKRK can be used for drug delivery .
|
-
- HY-172278B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG5000-CGKRK can be used for drug delivery .
|
-
- HY-172278
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG1000-CGKRK can be used for drug delivery .
|
-
- HY-172681
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG2000-VIP can be used for drug delivery .
|
-
- HY-172682
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG5000-VIP can be used for drug delivery .
|
-
- HY-172681A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG3400-VIP can be used for drug delivery .
|
-
- HY-W1048533C
-
|
Biotin-PEG5000-Thiol
|
Biochemical Assay Reagents
|
|
Biotin-PEG5000-SH (Biotin-PEG5000-Thiol) is a biotin PEG polymer containing a thiol (-SH). Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
-
- HY-W1048533A
-
|
Biotin-PEG2000-Thiol,
|
Biochemical Assay Reagents
|
|
Biotin-PEG2000-SH (Biotin-PEG2000-Thiol) is a biotin PEG polymer containing a thiol (-SH). Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
-
- HY-W1048533E
-
|
Biotin-PEG20000-Thiol
|
Biochemical Assay Reagents
|
|
Biotin-PEG20000-SH (Biotin-PEG20000-Thiol) is a biotin PEG polymer containing a thiol (-SH). Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
-
- HY-172276C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG3400-R8 can be used for drug delivery .
|
-
- HY-172276B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG5000-R8 can be used for drug delivery .
|
-
- HY-172482A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG3400-TAASGVRSMH can be used for drug delivery .
|
-
- HY-172277B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG5000-R9 can be used for drug delivery .
|
-
- HY-172687A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). CSTSMLKAC is capable of mediating selective homing of phage to ischemic heart tissue. DSPE-PEG3400-CSTSMLKAC can be used for drug delivery .
|
-
- HY-172726
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG2000-EB1 can be used for drug delivery .
|
-
- HY-172726A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG3400-EB1 can be used for drug delivery .
|
-
- HY-172688
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). CSTSMLKAC is capable of mediating selective homing of phage to ischemic heart tissue. DSPE-PEG5000-CSTSMLKAC can be used for drug delivery .
|
-
- HY-172277C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG3400-R9 can be used for drug delivery .
|
-
- HY-172277
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG1000-R9 can be used for drug delivery .
|
-
- HY-W190865
-
|
Biotin-PEG5-COOH
|
Biochemical Assay Reagents
|
|
Biotin-PEG5-acid (Biotin-PEG5-COOH) is a biotin-PEG compound containing a carboxyl group (-COOH) that can be used to react with an amine group (NH2) to form a stable amide bond. Biotin-PEG5-acid can be used for protein labeling and drug delivery research .
|
-
- HY-116027B
-
|
Biotin-PEG11-COOH
|
Biochemical Assay Reagents
|
|
Biotin-PEG11-acid (Biotin-PEG11-COOH) is a biotin-PEG compound containing a carboxyl group (-COOH) that can be used to react with an amine group (NH2) to form a stable amide bond. Biotin-PEG11-acid can be used for protein labeling and drug delivery research .
|
-
- HY-174948
-
|
NHS-PEG1000-Aldehyde
|
Biochemical Assay Reagents
|
|
NHS-PEG1000-CHO (NHS-PEG1000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
- HY-174948C
-
|
NHS-PEG5000-Aldehyde
|
Biochemical Assay Reagents
|
|
NHS-PEG5000-CHO (NHS-PEG5000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
- HY-172708A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG3400-PP1 can be used for drug delivery .
|
-
- HY-172473A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG34000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG3400-NGR can be used for drug delivery .
|
-
- HY-172503A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG3400-KAA can be used for drug delivery .
|
-
- HY-174926
-
|
|
Biochemical Assay Reagents
|
|
8-Arm PEG10000-COOH is a compound composed of PEG units and carboxyl (-COOH) groups, which can be used for drug delivery .
|
- HY-174926B
-
|
|
Biochemical Assay Reagents
|
|
8-Arm PEG40000-COOH is a compound composed of PEG units and carboxyl (-COOH) groups, which can be used for drug delivery .
|
- HY-172274
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-APRPG is a PEG compound which composed of DSPE and a APRPG peptide. DSPE-PEG1000-APRPG can be used for drug delivery .
|
- HY-172274B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-APRPG is a PEG compound which composed of DSPE and a APRPG peptide. DSPE-PEG5000-APRPG can be used for drug delivery .
|
- HY-172680
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG1000-VIP can be used for drug delivery .
|
- HY-174937
-
|
DNP-PEG3-COOH
|
Biochemical Assay Reagents
|
|
DNP-PEG3-acid (DNP-PEG3-COOH) is a compound composed of 2,4-dinitroaniline (DNP), three PEG units, and propionic acid, which can be used for drug delivery.
|
- HY-174936
-
|
DNP-PEG8-acid
|
Biochemical Assay Reagents
|
|
DNP-PEG8-COOH (DNP-PEG8-acid) is a compound composed of 2,4-dinitroaniline (DNP), three PEG units, and a carboxyl group (-COOH) that can be used for drug delivery.
|
- HY-W1048533D
-
|
Biotin-PEG10000-Thiol
|
Biochemical Assay Reagents
|
|
Biotin-PEG10000-SH (Biotin-PEG10000-Thiol) is a biotin PEG polymer containing a thiol (-SH). Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
- HY-W1048533I
-
|
Biotin-PEG3400-Thiol
|
Biochemical Assay Reagents
|
|
Biotin-PEG3400-SH (Biotin-PEG3400-Thiol) is a biotin PEG polymer containing a thiol (-SH). Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
- HY-W1048533J
-
|
Biotin-PEG40000-Thiol
|
Biochemical Assay Reagents
|
|
Biotin-PEG40000-SH (Biotin-PEG40000-Thiol) is a biotin PEG polymer containing a thiol (-SH). Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
- HY-W1051916C
-
|
|
Biochemical Assay Reagents
|
|
NH2-PEG5000-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG5000-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.
|
- HY-W1051916A
-
|
|
Biochemical Assay Reagents
|
|
NH2-PEG2000-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG2000-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.
|
- HY-W1051916H
-
|
|
Biochemical Assay Reagents
|
|
NH2-PEG400-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG400-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.
|
- HY-W1051916B
-
|
|
Biochemical Assay Reagents
|
|
NH2-PEG3400-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG3400-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.
|
- HY-W1051916I
-
|
|
Biochemical Assay Reagents
|
|
NH2-PEG600-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG600-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.
|
- HY-W1051916
-
|
|
Biochemical Assay Reagents
|
|
NH2-PEG1000-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG1000-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.
|
- HY-W1051916D
-
|
|
Biochemical Assay Reagents
|
|
NH2-PEG10000-DBCO is a compound composed of an amino group, PEG, and DBCO, and can be used for drug delivery. NH2-PEG10000-DBCO contains clickable functional groups DBCO and PEG, and can undergo a ring-strain-driven acetylene-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.
|
- HY-W460261A
-
|
|
Biochemical Assay Reagents
|
|
4-Arm-PEG2000-COOH is a compound composed of PEG units and carboxyl (-COOH) groups, which can be used for drug delivery .
|
- HY-W460261D
-
|
|
Biochemical Assay Reagents
|
|
4-Arm-PEG20000-COOH is a compound composed of PEG units and carboxyl (-COOH) groups, which can be used for drug delivery .
|
- HY-W460261B
-
|
|
Biochemical Assay Reagents
|
|
4-Arm-PEG5000-COOH is a compound composed of PEG units and carboxyl (-COOH) groups, which can be used for drug delivery .
|
- HY-W460261C
-
|
|
Biochemical Assay Reagents
|
|
4-Arm-PEG10000-COOH is a compound composed of PEG units and carboxyl (-COOH) groups, which can be used for drug delivery .
|
- HY-172276
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG1000-R8 can be used for drug delivery .
|
- HY-172483
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3000-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG3000-TAASGVRSMH can be used for drug delivery .
|
- HY-172481
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG1000-TAASGVRSMH can be used for drug delivery .
|
- HY-172482
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG2000-TAASGVRSMH can be used for drug delivery .
|
- HY-W1048669A
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG5000-DMG is a compound composed of biotin, PEG, and myristoyl-sn-glycerol, used for drug delivery. Biotin forms a stable non-covalent bond with streptavidin.
|
- HY-W1048669I
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG3400-DMG is a compound composed of biotin, PEG, and myristoyl-sn-glycerol, used for drug delivery. Biotin forms a stable non-covalent bond with streptavidin.
|
- HY-W1048669H
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG2000-DMG is a compound composed of biotin, PEG, and myristoyl-sn-glycerol, used for drug delivery. Biotin forms a stable non-covalent bond with streptavidin.
|
- HY-W1048669E
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG1000-DMG is a compound composed of biotin, PEG, and myristoyl-sn-glycerol, used for drug delivery. Biotin forms a stable non-covalent bond with streptavidin.
|
- HY-172727
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG5000-EB1 can be used for drug delivery .
|
- HY-172686
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). CSTSMLKAC is capable of mediating selective homing of phage to ischemic heart tissue. DSPE-PEG1000-CSTSMLKAC can be used for drug delivery .
|
- HY-172725
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG1000-EB1 can be used for drug delivery .
|
- HY-182100
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-MTP is a PEG compound which composed of DSPE and a muscle-targeting peptide (MTP). MTP is a muscle-targeting peptide with the property of targeting muscle tissue. DSPE-PEG1000-MTP can be used for drug delivery .
|
- HY-182100B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-MTP is a PEG compound which composed of DSPE and a muscle-targeting peptide (MTP). MTP is a muscle-targeting peptide with the property of targeting muscle tissue. DSPE-PEG3400-MTP can be used for drug delivery .
|
- HY-182100C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-MTP is a PEG compound which composed of DSPE and a muscle-targeting peptide (MTP). MTP is a muscle-targeting peptide with the property of targeting muscle tissue. DSPE-PEG5000-MTP can be used for drug delivery .
|
- HY-182100A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-MTP is a PEG compound which composed of DSPE and a muscle-targeting peptide (MTP). MTP is a muscle-targeting peptide with the property of targeting muscle tissue. DSPE-PEG2000-MTP can be used for drug delivery .
|
- HY-172690A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .
|
- HY-172689
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .
|
- HY-179189H
-
|
Folate-PEG10000-ACA
|
Biochemical Assay Reagents
|
|
FA-PEG10000-ACA (Folate-PEG10000-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.
|
- HY-179189B
-
|
Folate-PEG1000-ACA
|
Biochemical Assay Reagents
|
|
FA-PEG1000-ACA (Folate-PEG1000-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.
|
- HY-179189C
-
|
Folate-PEG2000-ACA
|
Biochemical Assay Reagents
|
|
FA-PEG2000-ACA (Folate-PEG2000-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.
|
- HY-179189D
-
|
Folate-PEG3400-ACA
|
Biochemical Assay Reagents
|
|
FA-PEG3400-ACA (Folate-PEG3400-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.
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- HY-179189E
-
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Folate-PEG5000-ACA
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Biochemical Assay Reagents
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FA-PEG5000-ACA (Folate-PEG5000-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.
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- HY-179189
-
|
Folate-PEG400-ACA
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Biochemical Assay Reagents
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FA-PEG400-ACA (Folate-PEG400-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.
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- HY-179189A
-
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Folate-PEG600-ACA
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Biochemical Assay Reagents
|
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FA-PEG600-ACA (Folate-PEG600-ACA) is a compound composed of Folic acid (HY-16637), PEG, and acrylamide. Folic acid (-FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery.
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- HY-174948B
-
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NHS-PEG3400-Aldehyde
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Biochemical Assay Reagents
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NHS-PEG3400-CHO (NHS-PEG3400-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
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- HY-174948A
-
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NHS-PEG2000-Aldehyde
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Biochemical Assay Reagents
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NHS-PEG2000-CHO (NHS-PEG2000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
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- HY-182101B
-
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Biochemical Assay Reagents
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DSPE-PEG3400-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a muscle-targeting peptide VHPKQHRGGSKGC (HY-P11088). GNYTCEVTELTREGETIIELK is a peptide that can bind to VCAM1. DSPE-PEG3400-GNYTCEVTELTREGETIIELK can be used for drug delivery .
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- HY-172504
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Biochemical Assay Reagents
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DSPE-PEG5000-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG5000-KAA can be used for drug delivery .
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- HY-182101A
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Biochemical Assay Reagents
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|
DSPE-PEG2000-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a muscle-targeting peptide VHPKQHRGGSKGC (HY-P11088). GNYTCEVTELTREGETIIELK is a peptide that can bind to VCAM1. DSPE-PEG2000-GNYTCEVTELTREGETIIELK can be used for drug delivery .
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- HY-182101
-
|
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Biochemical Assay Reagents
|
|
DSPE-PEG1000-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a muscle-targeting peptide VHPKQHRGGSKGC (HY-P11088). GNYTCEVTELTREGETIIELK is a peptide that can bind to VCAM1. DSPE-PEG1000-GNYTCEVTELTREGETIIELK can be used for drug delivery .
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- HY-172685
-
|
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Biochemical Assay Reagents
|
|
DSPE-PEG5000-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG5000-GRGDS can be used for drug delivery .
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- HY-172474
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG5000-NGR can be used for drug delivery .
|
- HY-172502
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG1000-KAA can be used for drug delivery .
|
- HY-172684A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG3400-GRGDS can be used for drug delivery .
|
- HY-172709
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG5000-PP1 can be used for drug delivery .
|
- HY-172472
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG1000-NGR can be used for drug delivery .
|
- HY-172684
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG2000-GRGDS can be used for drug delivery .
|
- HY-172503
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG2000-KAA can be used for drug delivery .
|
- HY-172708
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG2000-PP1 can be used for drug delivery .
|
- HY-172683
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG1000-GRGDS can be used for drug delivery .
|
- HY-172473
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG2000-NGR can be used for drug delivery .
|
- HY-182101C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a muscle-targeting peptide VHPKQHRGGSKGC (HY-P11088). GNYTCEVTELTREGETIIELK is a peptide that can bind to VCAM1. DSPE-PEG5000-GNYTCEVTELTREGETIIELK can be used for drug delivery .
|
- HY-172707
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG1000-PP1 can be used for drug delivery .
|
- HY-172497
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG2000-CREKA can be used for drug delivery .
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- HY-172701
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG1000-NYZL1 can be used for drug delivery .
|
- HY-172696
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG2000-WYRGRL can be used for drug delivery .
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- HY-172496
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG1000-CREKA can be used for drug delivery .
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- HY-172696A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG3400-WYRGRL can be used for drug delivery .
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- HY-172702A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG3400-NYZL1 can be used for drug delivery .
|
- HY-172498
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG5000-CREKA can be used for drug delivery .
|
- HY-172695
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG1000-WYRGRL can be used for drug delivery .
|
- HY-172497A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG3400-CREKA can be used for drug delivery .
|
- HY-172697
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG5000-WYRGRL can be used for drug delivery .
|
- HY-172702
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG2000-NYZL1 can be used for drug delivery .
|
- HY-172703
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG5000-NYZL1 can be used for drug delivery .
|
- HY-172468
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-CTT2 is a PEG compound which composed of DSPE and a gelatinase inhibitor (CTT2 (CTTHWGFTLC)). CTT2 (CTTHWGFTLC) has the ability to specifically target tumors. DSPE-PEG5000-CTT2 can be used for drug delivery .
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- HY-172470A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-GE11 is a PEG compound which composed of DSPE and an EGFR targeting peptide (GE11). GE11 can be used for EGFR overexpressed cancer cells. DSPE-PEG3400-GE11 can be used for drug delivery .
|
- HY-172466
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-CTT2 is a PEG compound which composed of DSPE and a gelatinase inhibitor (CTT2 (CTTHWGFTLC)). CTT2 (CTTHWGFTLC) has the ability to specifically target tumors. DSPE-PEG1000-CTT2 can be used for drug delivery .
|
- HY-172275A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG2000-pPB can be used for drug delivery .
|
- HY-172484
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG1000-LTLRWVGLMS can be used for drug delivery .
|
- HY-172485A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG3400-LTLRWVGLMS can be used for drug delivery .
|
- HY-172467
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-CTT2 is a PEG compound which composed of DSPE and a gelatinase inhibitor (CTT2 (CTTHWGFTLC)). CTT2 (CTTHWGFTLC) has the ability to specifically target tumors. DSPE-PEG2000-CTT2 can be used for drug delivery .
|
- HY-172486
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG5000-LTLRWVGLMS can be used for drug delivery .
|
- HY-172466A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-CTT2 is a PEG compound which composed of DSPE and a gelatinase inhibitor (CTT2 (CTTHWGFTLC)). CTT2 (CTTHWGFTLC) has the ability to specifically target tumors. DSPE-PEG1000-CTT2 can be used for drug delivery .
|
- HY-172275
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG1000-pPB can be used for drug delivery .
|
- HY-172469
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-GE11 is a PEG compound which composed of DSPE and an EGFR targeting peptide (GE11). GE11 can be used for EGFR overexpressed cancer cells. DSPE-PEG1000-GE11 can be used for drug delivery .
|
- HY-172275B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG5000-pPB can be used for drug delivery .
|
- HY-172275C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG3400-pPB can be used for drug delivery .
|
- HY-172485
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG2000-LTLRWVGLMS can be used for drug delivery .
|
- HY-172352
-
|
|
Biochemical Assay Reagents
|
|
PEG900 tosylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-172352A
-
|
|
Biochemical Assay Reagents
|
|
PEG2000 tosylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-172723A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG3400-T7 can be used for drug delivery .
|
- HY-172724
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG5000-T7 can be used for drug delivery .
|
- HY-182099B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-DHLASLWWGTEL is a PEG compound which composed of DSPE and a GPC3 targeting peptide DHLASLWWGTEL. The DHLASLWWGTEL peptide partially and specifically binds to GPC3-positive cells, achieving precise targeting. DSPE-PEG3400-DHLASLWWGTEL can be used for drug delivery .
|
- HY-182092
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-Asp6 is a PEG compound which composed of DSPE and a Asp6 peptide. DSPE-PEG1000-Asp6 achieves bone-targeted delivery of drugs or imaging agents by binding to bone tissue with the Asp6 peptide through high affinity .
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- HY-182092A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-Asp6 is a PEG compound which composed of DSPE and a Asp6 peptide. DSPE-PEG5000-Asp6 achieves bone-targeted delivery of drugs or imaging agents by binding to bone tissue with the Asp6 peptide through high affinity .
|
- HY-182099A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-DHLASLWWGTEL is a PEG compound which composed of DSPE and a GPC3 targeting peptide DHLASLWWGTEL. The DHLASLWWGTEL peptide partially and specifically binds to GPC3-positive cells, achieving precise targeting. DSPE-PEG2000-DHLASLWWGTEL can be used for drug delivery .
|
- HY-182092C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Asp6 is a PEG compound which composed of DSPE and a Asp6 peptide. DSPE-PEG3400-Asp6 achieves bone-targeted delivery of drugs or imaging agents by binding to bone tissue with the Asp6 peptide through high affinity .
|
- HY-140696D
-
|
mPEG10000-Hydroxy; Polyethylene glycol monomethyl ether 10000
|
Biochemical Assay Reagents
|
|
m-PEG10000-OH (mPEG10000-Hydroxy; Polyethylene glycol monomethyl ether 10000) is a hydroxyl-terminated methoxylated polyethylene glycol (PEG-based) compound that serves as a linker for PROTACs. m-PEG10000-OH is applicable to research on healthcare-associated infections .
|
- HY-W1120572
-
|
Boc-NH-PEG20-CH2CH2NH2
|
Biochemical Assay Reagents
|
|
t-Boc-N-Amido-PEG20-amine (Boc-NH-PEG20-CH2CH2NH2) is a compound composed of NH2, PEG units and t-Boc-N-Amido, which can be used for drug delivery.
|
- HY-174906
-
|
|
Biochemical Assay Reagents
|
|
Bis-PEG1000-COOH is a disubstituted PEG derivative with the same functional group. The carboxylic acid group in Bis-PEG1000-COOH can react with other compounds containing amino, hydroxyl and other functional groups to form stable chemical bonds, which can be used for drug delivery .
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- HY-182099
-
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|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-DHLASLWWGTEL is a PEG compound which composed of DSPE and a GPC3 targeting peptide DHLASLWWGTEL. The DHLASLWWGTEL peptide partially and specifically binds to GPC3-positive cells, achieving precise targeting. DSPE-PEG1000-DHLASLWWGTEL can be used for drug delivery .
|
- HY-182099C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-DHLASLWWGTEL is a PEG compound which composed of DSPE and a GPC3 targeting peptide DHLASLWWGTEL. The DHLASLWWGTEL peptide partially and specifically binds to GPC3-positive cells, achieving precise targeting. DSPE-PEG5000-DHLASLWWGTEL can be used for drug delivery .
|
- HY-182092B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-Asp6 is a PEG compound which composed of DSPE and a Asp6 peptide. DSPE-PEG2000-Asp6 achieves bone-targeted delivery of drugs or imaging agents by binding to bone tissue with the Asp6 peptide through high affinity .
|
- HY-172722
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG1000-T7 can be used for drug delivery .
|
- HY-172491
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-ESBP is a PEG compound which composed of DSPE and a E-selectin-binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells .
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- HY-172491A
-
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Biochemical Assay Reagents
|
|
DSPE-PEG3400-ESBP is a PEG compound which composed of DSPE and a E-selectin-binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells .
|
- HY-172490
-
|
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Biochemical Assay Reagents
|
|
DSPE-PEG1000-ESBP is a PEG compound which composed of DSPE and a E-selectin-binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells .
|
- HY-172492
-
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Biochemical Assay Reagents
|
|
DSPE-PEG5000-ESBP is a PEG compound which composed of DSPE and a E-selectin-binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells .
|
- HY-W1123941
-
|
Dopamine-PEG9-Azide
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Biochemical Assay Reagents
|
|
Dopamine-PEG-N3 (Dopamine-PEG-Azide is a compound composed of dopamine, PEG segments and an azide group (-N3). Dopamine-PEG-N3 can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials. Dopamine-PEG-N3 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group.
|
- HY-140895B
-
|
Biotin-PEG10000-NH2
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Biochemical Assay Reagents
|
|
Biotin-PEG10000-Amine (Biotin-PEG10000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
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- HY-172280A
-
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Biochemical Assay Reagents
|
|
DSPE-PEG21000-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG2000-Octreotide can be used for drug delivery .
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- HY-176206E
-
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Biochemical Assay Reagents
|
|
Biotin-PEG20000-COOH is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG20000-COOH can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
|
- HY-140895C
-
|
Biotin-PEG20000-NH2
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Biochemical Assay Reagents
|
|
Biotin-PEG20000-Amine (Biotin-PEG20000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
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- HY-172280
-
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Biochemical Assay Reagents
|
|
DSPE-PEG1000-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG1000-Octreotide can be used for drug delivery .
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- HY-172699A
-
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Biochemical Assay Reagents
|
|
DSPE-PEG3400-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG3400-ANG can be used for drug delivery .
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- HY-176206D
-
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Biochemical Assay Reagents
|
|
Biotin-PEG10000-COOH is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG10000-COOH can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
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- HY-176206H
-
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Biochemical Assay Reagents
|
|
Biotin-PEG40000-COOH is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG40000-COOH can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
|
- HY-172281
-
|
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Biochemical Assay Reagents
|
|
DSPE-PEG1000-CCK8 is a PEG compound which composed of DSPE and a Cholecystokinin-8 (CCK8). Cholecystokinin-8 has the activity of peptide regulating gallbladder contraction and digestive system function. DSPE-PEG1000-CCK8 can be used for drug delivery .
|
- HY-140895D
-
|
Biotin-PEG40000-NH2
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Biochemical Assay Reagents
|
|
Biotin-PEG40000-Amine (Biotin-PEG40000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
- HY-172280C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG3400-Octreotide can be used for drug delivery .
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- HY-172281B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-CCK8 is a PEG compound which composed of DSPE and a Cholecystokinin-8 (CCK8). Cholecystokinin-8 has the activity of peptide regulating gallbladder contraction and digestive system function. DSPE-PEG5000-CCK8 can be used for drug delivery .
|
- HY-176206
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG1000-COOH is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG1000-COOH can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
|
- HY-172698
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG1000-ANG can be used for drug delivery .
|
- HY-176206A
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG2000-COOH is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG2000-COOH can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
|
- HY-172700
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG5000-ANG can be used for drug delivery .
|
- HY-172280B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG5000-Octreotide can be used for drug delivery .
|
- HY-176206B
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG3400-COOH is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG3400-COOH can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
|
- HY-140895A
-
|
Biotin-PEG5000-NH2
|
Biochemical Assay Reagents
|
|
Biotin-PEG5000-Amine (Biotin-PEG5000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
- HY-176206C
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG5000-COOH is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG5000-COOH can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
|
- HY-172281A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-CCK8 is a PEG compound which composed of DSPE and a Cholecystokinin-8 (CCK8). Cholecystokinin-8 has the activity of peptide regulating gallbladder contraction and digestive system function. DSPE-PEG2000-CCK8 can be used for drug delivery .
|
- HY-177204A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-WLSEAGPVVTVRALRGTGSW is a PEG compound which composed of DSPE and a cardiomyocyte specific peptide (WLSEAGPVVTVRALRGTGSW) (HY-P3436). WLSEAGPVVTVRALRGTGSW exhibits high cardiomyocyte targeting primarily through selective binding to specific receptors or molecules on the surface of cardiomyocytes. DSPE-PEG1000-WLSEAGPVVTVRALRGTGSW can be used for drug delivery .
|
- HY-172464
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-cRGD is a PEG compound which composed of DSPE and an αvβ3 targeting peptide (cRGD). cRGD peptide can specifically bind to αvβ3 on the surface of many cancer cells and neovascular cells. DSPE-PEG2000-cRGD can be used for drug delivery .
|
- HY-177204B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-WLSEAGPVVTVRALRGTGSW is a PEG compound which composed of DSPE and a cardiomyocyte specific peptide (WLSEAGPVVTVRALRGTGSW) (HY-P3436). WLSEAGPVVTVRALRGTGSW exhibits high cardiomyocyte targeting primarily through selective binding to specific receptors or molecules on the surface of cardiomyocytes. DSPE-PEG3400-WLSEAGPVVTVRALRGTGSW can be used for drug delivery .
|
- HY-177204C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-WLSEAGPVVTVRALRGTGSW is a PEG compound which composed of DSPE and a cardiomyocyte specific peptide (WLSEAGPVVTVRALRGTGSW) (HY-P3436). WLSEAGPVVTVRALRGTGSW exhibits high cardiomyocyte targeting primarily through selective binding to specific receptors or molecules on the surface of cardiomyocytes. DSPE-PEG5000-WLSEAGPVVTVRALRGTGSW can be used for drug delivery .
|
- HY-172464A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-cRGD is a PEG compound which composed of DSPE and an αvβ3 targeting peptide (cRGD). cRGD peptide can specifically bind to αvβ3 on the surface of many cancer cells and neovascular cells. DSPE-PEG3400-cRGD can be used for drug delivery .
|
- HY-172463
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-cRGD is a PEG compound which composed of DSPE and an αvβ3 targeting peptide (cRGD). cRGD peptide can specifically bind to αvβ3 on the surface of many cancer cells and neovascular cells. DSPE-PEG1000-cRGD can be used for drug delivery .
|
- HY-W440891
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-OH is a hydroxyl terminated phospholipid PEG polymer. The hydrophobic tails allow for the encapsulation and congregation of other hydrophobic drugs. The polymer can be used to prepare liposomes or lipid nanoparticles. Hydroxyl terminal can further derivatize the compound.
|
- HY-179193E
-
|
N3-PEG5000-OPSS
|
Biochemical Assay Reagents
|
|
Azide-PEG5000-OPSS (N3-PEG5000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG5000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-179193C
-
|
N3-PEG2000-OPSS
|
Biochemical Assay Reagents
|
|
Azide-PEG2000-OPSS (N3-PEG2000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG2000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-179193H
-
|
N3-PEG10000-OPSS
|
Biochemical Assay Reagents
|
|
Azide-PEG10000-OPSS (N3-PEG10000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG10000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-179193B
-
|
N3-PEG1000-OPSS
|
Biochemical Assay Reagents
|
|
Azide-PEG1000-OPSS (N3-PEG1000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG1000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-179193D
-
|
N3-PEG3400-OPSS
|
Biochemical Assay Reagents
|
|
Azide-PEG3400-OPSS (N3-PEG3400-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG3400-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-179193A
-
|
N3-PEG600-OPSS
|
Biochemical Assay Reagents
|
|
Azide-PEG600-OPSS (N3-PEG600-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG600-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-179193
-
|
N3-PEG400-OPSS
|
Biochemical Assay Reagents
|
|
Azide-PEG400-OPSS (N3-PEG400-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG400-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-172271C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-LyP-1 is a PEG compound which composed of DSPE and a nine residue peptide (LyP-1) (HY-P2526). LyP-1 targets tumor-associated lymphatic vessels and macrophages .
|
- HY-172477
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG5000-YIGSR can be used for drug delivery .
|
- HY-172479
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-F3 is a PEG compound which composed of DSPE and a nucleolin targeting peptide (F3). F3 peptide can specifically bind to cell surface nucleolin and undergo an effective cell surface to nucleus transport. DSPE-PEG2000-F3 can be used for drug delivery .
|
- HY-172479A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-F3 is a PEG compound which composed of DSPE and a nucleolin targeting peptide (F3). F3 peptide can specifically bind to cell surface nucleolin and undergo an effective cell surface to nucleus transport. DSPE-PEG3400-F3 can be used for drug delivery .
|
- HY-172475
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG1000-YIGSR can be used for drug delivery .
|
- HY-172478
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-F3 is a PEG compound which composed of DSPE and a nucleolin targeting peptide (F3). F3 peptide can specifically bind to cell surface nucleolin and undergo an effective cell surface to nucleus transport. DSPE-PEG1000-F3 can be used for drug delivery .
|
- HY-172480
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-F3 is a PEG compound which composed of DSPE and a nucleolin targeting peptide (F3). F3 peptide can specifically bind to cell surface nucleolin and undergo an effective cell surface to nucleus transport. DSPE-PEG5000-F3 can be used for drug delivery .
|
- HY-172476
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG2000-YIGSR can be used for drug delivery .
|
- HY-172476A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG3400-YIGSR can be used for drug delivery .
|
- HY-172694
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-TH is a PEG compound which composed of DSPE and a pH-responsive cell penetrating peptide (TH). TH is activated in an acidic environment (such as the tumor microenvironment) and can selectively carry small molecules, oligonucleotides, proteins, etc. into tumor cells .
|
- HY-172693
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-TH is a PEG compound which composed of DSPE and a pH-responsive cell penetrating peptide (TH). TH is activated in an acidic environment (such as the tumor microenvironment) and can selectively carry small molecules, oligonucleotides, proteins, etc. into tumor cells .
|
- HY-W1123941A
-
|
Dopamine-PEG-Azide
|
Biochemical Assay Reagents
|
|
Dopamine-PEG13-N3 (Dopamine-PEG-Azide) is a compound composed of dopamine, PEG segments and an azide group (-N3). Dopamine-PEG13-N3 can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials. Dopamine-PEG13-N3 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group.
|
- HY-182097A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a peptide mimicking the function of CD47 (GNYTCEVTELSREGKTVIELK). Modifying the surface of LNPs with GNYTCEVTELSREGKTVIELK significantly reduced the recognition and clearance of LNPs by the mononuclear phagocytic system (MPS), and decreased their accumulation in non-target tissues such as the liver and spleen. DSPE-PEG3400-GNYTCEVTELTREGETIIELK can be used for drug delivery .
|
- HY-172499
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG1000-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.
|
- HY-182097
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a peptide mimicking the function of CD47 (GNYTCEVTELSREGKTVIELK). Modifying the surface of LNPs with GNYTCEVTELSREGKTVIELK significantly reduced the recognition and clearance of LNPs by the mononuclear phagocytic system (MPS), and decreased their accumulation in non-target tissues such as the liver and spleen. DSPE-PEG1000-GNYTCEVTELTREGETIIELK can be used for drug delivery .
|
- HY-172495
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3000-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG3000-iRGD can be used for drug delivery .
|
- HY-172493
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG1000-iRGD can be used for drug delivery .
|
- HY-172494
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG2000-iRGD can be used for agent delivery .
|
- HY-182097B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a peptide mimicking the function of CD47 (GNYTCEVTELSREGKTVIELK). Modifying the surface of LNPs with GNYTCEVTELSREGKTVIELK significantly reduced the recognition and clearance of LNPs by the mononuclear phagocytic system (MPS), and decreased their accumulation in non-target tissues such as the liver and spleen. DSPE-PEG5000-GNYTCEVTELTREGETIIELK can be used for drug delivery .
|
- HY-172501
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG5000-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.
|
- HY-172494A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG3400-iRGD can be used for drug delivery .
|
- HY-172500A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG3400-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.
|
- HY-172500
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG2000-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.
|
- HY-172706
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-RVG29 is a PEG compound which composed of DSPE and a Rabies virus glycoprotein 29 (RVG29). RVG29 can bind specifically to the nicotinic acetylcholine receptor (nAChR) at the blood-brain barrier (BBB) and cross over the BBB .
|
- HY-172272B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-A7R is a PEG compound which composed of DSPE and a tumor vascular targeting peptide (A7R). A7R exhibits high affinity and specificity for VEGFR-2, which is overexpressed in various tumors .
|
- HY-172272A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-A7R is a PEG compound which composed of DSPE and a tumor vascular targeting peptide (A7R). A7R exhibits high affinity and specificity for VEGFR-2, which is overexpressed in various tumors .
|
- HY-172704
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-RVG29 is a PEG compound which composed of DSPE and a Rabies virus glycoprotein 29 (RVG29). RVG29 can bind specifically to the nicotinic acetylcholine receptor (nAChR) at the blood-brain barrier (BBB) and cross over the BBB .
|
- HY-172272
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-A7R is a PEG compound which composed of DSPE and a tumor vascular targeting peptide (A7R). A7R exhibits high affinity and specificity for VEGFR-2, which is overexpressed in various tumors .
|
- HY-172272C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-A7R is a PEG compound which composed of DSPE and a tumor vascular targeting peptide (A7R). A7R exhibits high affinity and specificity for VEGFR-2, which is overexpressed in various tumors .
|
- HY-Y0873A1
-
|
Polyethylene glycol 100000
|
Biochemical Assay Reagents
|
|
PEG100000 (Polyethylene glycol 100000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
- HY-Y0873A9
-
|
Polyethylene glycol 2000000
|
Biochemical Assay Reagents
|
|
PEG2000000 (Polyethylene glycol 2000000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
- HY-Y0873A2
-
|
Polyethylene glycol 600000
|
Biochemical Assay Reagents
|
|
PEG600000 (Polyethylene glycol 600000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
- HY-Y0873A5
-
|
Polyethylene glycol 200000
|
Biochemical Assay Reagents
|
|
PEG200000 (Polyethylene glycol 200000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
- HY-Y0873A7
-
|
Polyethylene glycol 900000
|
Biochemical Assay Reagents
|
|
PEG900000 (Polyethylene glycol 900000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
- HY-Y0873A4
-
|
Polyethylene glycol 4000000
|
Biochemical Assay Reagents
|
|
PEG4000000 (Polyethylene glycol 4000000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
- HY-Y0873A6
-
|
Polyethylene glycol 400000
|
Biochemical Assay Reagents
|
|
PEG400000 (Polyethylene glycol 400000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
- HY-Y0873B1
-
|
Polyethylene glycol 8000000
|
Biochemical Assay Reagents
|
|
PEG8000000 (Polyethylene glycol 8000000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
- HY-Y0873A3
-
|
Polyethylene glycol 1000000
|
Biochemical Assay Reagents
|
|
PEG1000000 (Polyethylene glycol 1000000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
- HY-Y0873A8
-
|
Polyethylene glycol 5000000
|
Biochemical Assay Reagents
|
|
PEG5000000 (Polyethylene glycol 5000000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
- HY-W1123941C
-
|
Dopamine-PEG2000-Azide
|
Biochemical Assay Reagents
|
|
Dopamine-PEG2000-N3 (Dopamine-PEG2000-Azide) is a compound composed of dopamine, PEG segments and an azide group (-N3). Dopamine-PEG2000-N3 can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials. Dopamine-PEG2000-N3 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group.
|
- HY-W1123941H
-
|
Dopamine-PEG10000-Azide
|
Biochemical Assay Reagents
|
|
Dopamine-PEG10000-N3 (Dopamine-PEG10000-Azide) is a compound composed of dopamine, PEG segments and an azide group (-N3). Dopamine-PEG10000-N3 can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials. Dopamine-PEG10000-N3 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group.
|
- HY-W1123941E
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Dopamine-PEG5000-Azide
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Biochemical Assay Reagents
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Dopamine-PEG5000-N3 (Dopamine-PEG5000-Azide) is a compound composed of dopamine, PEG segments and an azide group (-N3). Dopamine-PEG5000-N3 can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials. Dopamine-PEG5000-N3 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group.
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- HY-W1123941B
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Dopamine-PEG1000-Azide
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Biochemical Assay Reagents
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Dopamine-PEG1000-N3 (Dopamine-PEG1000-Azide) is a compound composed of dopamine, PEG segments and an azide group (-N3). Dopamine-PEG1000-N3 can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials. Dopamine-PEG1000-N3 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group.
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- HY-W1123941D
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Dopamine-PEG3400-Azide
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Biochemical Assay Reagents
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Dopamine-PEG3400-N3 (Dopamine-PEG3400-Azide) is a compound composed of dopamine, PEG segments and an azide group (-N3). Dopamine-PEG3400-N3 can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials. Dopamine-PEG3400-N3 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group.
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- HY-172488A
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Biochemical Assay Reagents
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DSPE-PEG3400-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG3400-K237 can be used for drug delivery .
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- HY-172489
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Biochemical Assay Reagents
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DSPE-PEG5000-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG5000-K237 can be used for drug delivery .
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- HY-172488
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Biochemical Assay Reagents
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DSPE-PEG2000-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG2000-K237 can be used for drug delivery .
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- HY-172487
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Biochemical Assay Reagents
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DSPE-PEG1000-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG1000-K237 can be used for drug delivery .
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- HY-177205C
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Biochemical Assay Reagents
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DSPE-PEG5000-CRPPR is a PEG compound which composed of DSPE and a?Heart-homing peptide?(CRPPR) (HY-P10641). CRPPR is a linear peptide containing arginine that has the ability to specifically bind to the cardiac endothelium and uses cysteine-rich protein-2 (CRIP-2) as its receptor. DSPE-PEG5000-CGKRK can be used for drug delivery .
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- HY-177205A
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Biochemical Assay Reagents
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DSPE-PEG1000-CRPPR is a PEG compound which composed of DSPE and a?Heart-homing peptide?(CRPPR) (HY-P10641). CRPPR is a linear peptide containing arginine that has the ability to specifically bind to the cardiac endothelium and uses cysteine-rich protein-2 (CRIP-2) as its receptor. DSPE-PEG1000-CGKRK can be used for drug delivery .
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- HY-177205B
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Biochemical Assay Reagents
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DSPE-PEG3400-CRPPR is a PEG compound which composed of DSPE and a?Heart-homing peptide?(CRPPR) (HY-P10641). CRPPR is a linear peptide containing arginine that has the ability to specifically bind to the cardiac endothelium and uses cysteine-rich protein-2 (CRIP-2) as its receptor. DSPE-PEG3400-CGKRK can be used for drug delivery .
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- HY-W598230A
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Biochemical Assay Reagents
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m-PEG2000-NH2 hydrochloride is a barrier permeation compound involved in the preparation of hybrid gels with adsorption and size exclusion chromatography (AdSEC) properties. m-PEG-NH2 helps AdSEC gels separate from complex biological mixtures such as blood, urine, sweat, and tears.
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- HY-172283A
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Biochemical Assay Reagents
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DSPE-PEG2000-BR2 is a PEG compound which composed of DSPE and a BR2. BR2 is a targeting peptide composed of 17 amino acids with the sequence RAGLQFPVGRLLRRLLR. It has the ability to assist cells to penetrate the membrane and can specifically target certain cells or tissues .
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- HY-172283C
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Biochemical Assay Reagents
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DSPE-PEG3400-BR2 is a PEG compound which composed of DSPE and a BR2. BR2 is a targeting peptide composed of 17 amino acids with the sequence RAGLQFPVGRLLRRLLR. It has the ability to assist cells to penetrate the membrane and can specifically target certain cells or tissues .
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- HY-172283
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Biochemical Assay Reagents
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DSPE-PEG1000-BR2 is a PEG compound which composed of DSPE and a BR2. BR2 is a targeting peptide composed of 17 amino acids with the sequence RAGLQFPVGRLLRRLLR. It has the ability to assist cells to penetrate the membrane and can specifically target certain cells or tissues .
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- HY-172283B
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Biochemical Assay Reagents
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DSPE-PEG5000-BR2 is a PEG compound which composed of DSPE and a BR2. BR2 is a targeting peptide composed of 17 amino acids with the sequence RAGLQFPVGRLLRRLLR. It has the ability to assist cells to penetrate the membrane and can specifically target certain cells or tissues .
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- HY-172711A
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Biochemical Assay Reagents
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DSPE-PEG3400-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG3400-R6H4 can be used for drug delivery .
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- HY-172273B
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Biochemical Assay Reagents
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DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .
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- HY-172273A
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Biochemical Assay Reagents
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DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .
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- HY-172273
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Biochemical Assay Reagents
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DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .
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- HY-172711
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Biochemical Assay Reagents
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DSPE-PEG2000-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG2000-R6H4 can be used for drug delivery .
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- HY-172712
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Biochemical Assay Reagents
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DSPE-PEG3000-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG3000-R6H4 can be used for drug delivery .
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- HY-172710
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Biochemical Assay Reagents
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DSPE-PEG1000-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG1000-R6H4 can be used for drug delivery .
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- HY-172273C
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Biochemical Assay Reagents
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DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .
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- HY-182095C
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Biochemical Assay Reagents
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DSPE-PEG5000-CTP is a PEG compound which composed of DSPE and a Cardiac-targeting peptide CTP (HY-P4094). CTP molecules that specifically recognize cardiac tissue and is primarily used for targeted drug delivery. CTP effectively recognizes and binds to specific receptors on the surface of cardiac cells, thereby achieving precise localization of drug molecules. DSPE-PEG5000-CTP can be used for drug delivery .
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- HY-182094C
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Biochemical Assay Reagents
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DSPE-PEG5000-KTP is a PEG compound which composed of DSPE and a Kidney-targeting peptide KTP (HY-P11069). KTP can interact with specific proteins on the surface of renal tubular epithelial cells or exhibit higher affinity in the specific renal microenvironment, tending to aggregate or be internalized within the renal tubular epithelium. DSPE-PEG5000-KTP can actively guide carriers such as nanomedicines, liposomes, and microspheres to the kidney .
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- HY-182094
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Biochemical Assay Reagents
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DSPE-PEG1000-KTP is a PEG compound which composed of DSPE and a Kidney-targeting peptide KTP (HY-P11069). KTP can interact with specific proteins on the surface of renal tubular epithelial cells or exhibit higher affinity in the specific renal microenvironment, tending to aggregate or be internalized within the renal tubular epithelium. DSPE-PEG1000-KTP can actively guide carriers such as nanomedicines, liposomes, and microspheres to the kidney .
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- HY-182095A
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Biochemical Assay Reagents
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DSPE-PEG2000-CTP is a PEG compound which composed of DSPE and a Cardiac-targeting peptide CTP (HY-P4094). CTP molecules that specifically recognize cardiac tissue and is primarily used for targeted drug delivery. CTP effectively recognizes and binds to specific receptors on the surface of cardiac cells, thereby achieving precise localization of drug molecules. DSPE-PEG2000-CTP can be used for drug delivery .
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- HY-182094A
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Biochemical Assay Reagents
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DSPE-PEG2000-KTP is a PEG compound which composed of DSPE and a Kidney-targeting peptide KTP (HY-P11069). KTP can interact with specific proteins on the surface of renal tubular epithelial cells or exhibit higher affinity in the specific renal microenvironment, tending to aggregate or be internalized within the renal tubular epithelium. DSPE-PEG2000-KTP can actively guide carriers such as nanomedicines, liposomes, and microspheres to the kidney .
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- HY-182094B
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Biochemical Assay Reagents
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DSPE-PEG3400-KTP is a PEG compound which composed of DSPE and a Kidney-targeting peptide KTP (HY-P11069). KTP can interact with specific proteins on the surface of renal tubular epithelial cells or exhibit higher affinity in the specific renal microenvironment, tending to aggregate or be internalized within the renal tubular epithelium. DSPE-PEG3400-KTP can actively guide carriers such as nanomedicines, liposomes, and microspheres to the kidney .
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- HY-182095B
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Biochemical Assay Reagents
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DSPE-PEG3400-CTP is a PEG compound which composed of DSPE and a Cardiac-targeting peptide CTP (HY-P4094). CTP molecules that specifically recognize cardiac tissue and is primarily used for targeted drug delivery. CTP effectively recognizes and binds to specific receptors on the surface of cardiac cells, thereby achieving precise localization of drug molecules. DSPE-PEG3400-CTP can be used for drug delivery .
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- HY-182095
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Biochemical Assay Reagents
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DSPE-PEG1000-CTP is a PEG compound which composed of DSPE and a Cardiac-targeting peptide CTP (HY-P4094). CTP molecules that specifically recognize cardiac tissue and is primarily used for targeted drug delivery. CTP effectively recognizes and binds to specific receptors on the surface of cardiac cells, thereby achieving precise localization of drug molecules. DSPE-PEG1000-CTP can be used for drug delivery .
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- HY-182096C
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Biochemical Assay Reagents
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DSPE-PEG5000-MG1 is a PEG compound which composed of DSPE and a MG1 peptide (HY-P11315). MG1 peptide is a M1 Microglia-targeting peptide. MG1 peptide can conjugate to anoparticles, crossing the BBB to precisely M1 microglia recognition and achieving controlled release and specific accumulation of drugs through intelligent molecular switching. DSPE-PEG5000-KTP can be used for drug delivery .
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- HY-182096A
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Biochemical Assay Reagents
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DSPE-PEG2000-MG1 is a PEG compound which composed of DSPE and a MG1 peptide (HY-P11315). MG1 peptide is a M1 Microglia-targeting peptide. MG1 peptide can conjugate to anoparticles, crossing the BBB to precisely M1 microglia recognition and achieving controlled release and specific accumulation of drugs through intelligent molecular switching. DSPE-PEG2000-KTP can be used for drug delivery .
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- HY-182096B
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Biochemical Assay Reagents
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DSPE-PEG3400-MG1 is a PEG compound which composed of DSPE and a MG1 peptide (HY-P11315). MG1 peptide is a M1 Microglia-targeting peptide. MG1 peptide can conjugate to anoparticles, crossing the BBB to precisely M1 microglia recognition and achieving controlled release and specific accumulation of drugs through intelligent molecular switching. DSPE-PEG3400-KTP can be used for drug delivery .
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- HY-182096
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Biochemical Assay Reagents
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DSPE-PEG1000-MG1 is a PEG compound which composed of DSPE and a MG1 peptide (HY-P11315). MG1 peptide is a M1 Microglia-targeting peptide. MG1 peptide can conjugate to anoparticles, crossing the BBB to precisely M1 microglia recognition and achieving controlled release and specific accumulation of drugs through intelligent molecular switching. DSPE-PEG1000-KTP can be used for drug delivery .
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- HY-172271A
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Biochemical Assay Reagents
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DSPE-PEG2000-LyP-1 is a PEG compound which composed of DSPE and a nine residue peptide (LyP-1) (HY-P2526). LyP-1 is a cyclic 9-amino-acids tumor homing peptide and selectively bind to p32 receptors overexpressed in various tumor-associated cells .
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- HY-172271B
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Biochemical Assay Reagents
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DSPE-PEG3000-LyP-1 is a PEG compound which composed of DSPE and a nine residue peptide (LyP-1) (HY-P2526). LyP-1 is a cyclic 9-amino-acids tumor homing peptide and selectively bind to p32 receptors overexpressed in various tumor-associated cells .
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- HY-172714A
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Biochemical Assay Reagents
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DSPE-PEG3400-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
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- HY-172714
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Biochemical Assay Reagents
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DSPE-PEG2000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
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- HY-172713
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Biochemical Assay Reagents
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DSPE-PEG1000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
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- HY-172715
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Biochemical Assay Reagents
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DSPE-PEG5000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
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- HY-174365H
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Biochemical Assay Reagents
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mPEG-NPC (MW 20000) is an important PEG derivative whose reactive groups can be used to modify proteins, peptides or any other compounds with available amino groups at lysine residues or N-terminus .
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- HY-W591332A
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Biochemical Assay Reagents
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mPEG1000-DMPE is a PEGylated 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE) compound with a methyl group at the?other?end of the PEG chain. The PEG polymer exhibits amphiphatic behavior and helps to form stable micelles in an aqueous solution. It can be used to prepare nanoparticles or liposomes for targeted drug delivery applications .
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- HY-174365D
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Biochemical Assay Reagents
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mPEG10000-NPC is an important PEG derivative whose reactive groups can be used to modify proteins, peptides or any other compounds with available amino groups at lysine residues or N-terminus .
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- HY-174365B
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Biochemical Assay Reagents
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mPEG3400-NPC is an important PEG derivative whose reactive groups can be used to modify proteins, peptides or any other compounds with available amino groups at lysine residues or N-terminus .
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- HY-174365E
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Biochemical Assay Reagents
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mPEG40000-NPC is an important PEG derivative whose reactive groups can be used to modify proteins, peptides or any other compounds with available amino groups at lysine residues or N-terminus .
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- HY-174365
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Biochemical Assay Reagents
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mPEG1000-NPC is an important PEG derivative whose reactive groups can be used to modify proteins, peptides or any other compounds with available amino groups at lysine residues or N-terminus .
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- HY-174365C
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Biochemical Assay Reagents
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mPEG5000-NPC is an important PEG derivative whose reactive groups can be used to modify proteins, peptides or any other compounds with available amino groups at lysine residues or N-terminus .
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- HY-174365A
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Biochemical Assay Reagents
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mPEG2000-NPC is an important PEG derivative whose reactive groups can be used to modify proteins, peptides or any other compounds with available amino groups at lysine residues or N-terminus .
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- HY-172271
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Biochemical Assay Reagents
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DSPE-PEG1000-Mal-Cys-CGNKRTRGC (Disulfide bridge: Cys2-Cys10) is a PEG compound which composed of DSPE and a nine residue peptide (LyP-1) (HY-P2526). LyP-1 is a cyclic 9-amino-acids tumor homing peptide and selectively bind to p32 receptors overexpressed in various tumor-associated cells .
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- HY-182098B
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Biochemical Assay Reagents
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DSPE-PEG3400-GALA is a PEG compound which composed of DSPE and a lung endothelium-targeting peptide GALA (HY-P5423). GALA is a pH-responsive amphipathic peptide consisting of 30 amino acids, which acts as a lung endothelium-targeting ligand. GALA undergoes a conformational transition from random coil to α-helix in an acidic environment at pH 5.0, thereby inducing endosomal membrane destabilization and fusion. GALA-modified liposomes traverse lung endothelial cells via clathrin-dependent endocytosis and transcytosis, and specifically accumulate in the lungs after intravenous injection. DSPE-PEG3400-GALA can be used for drug delivery .
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- HY-182098C
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Biochemical Assay Reagents
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DSPE-PEG5000-GALA is a PEG compound which composed of DSPE and a lung endothelium-targeting peptide GALA (HY-P5423). GALA is a pH-responsive amphipathic peptide consisting of 30 amino acids, which acts as a lung endothelium-targeting ligand. GALA undergoes a conformational transition from random coil to α-helix in an acidic environment at pH 5.0, thereby inducing endosomal membrane destabilization and fusion. GALA-modified liposomes traverse lung endothelial cells via clathrin-dependent endocytosis and transcytosis, and specifically accumulate in the lungs after intravenous injection. DSPE-PEG5000-GALA can be used for drug delivery .
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- HY-182098
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Biochemical Assay Reagents
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DSPE-PEG1000-GALA is a PEG compound which composed of DSPE and a lung endothelium-targeting peptide GALA (HY-P5423). GALA is a pH-responsive amphipathic peptide consisting of 30 amino acids, which acts as a lung endothelium-targeting ligand. GALA undergoes a conformational transition from random coil to α-helix in an acidic environment at pH 5.0, thereby inducing endosomal membrane destabilization and fusion. GALA-modified liposomes traverse lung endothelial cells via clathrin-dependent endocytosis and transcytosis, and specifically accumulate in the lungs after intravenous injection. DSPE-PEG1000-GALA can be used for drug delivery .
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- HY-182098A
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Biochemical Assay Reagents
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DSPE-PEG2000-GALA is a PEG compound which composed of DSPE and a lung endothelium-targeting peptide GALA (HY-P5423). GALA is a pH-responsive amphipathic peptide consisting of 30 amino acids, which acts as a lung endothelium-targeting ligand. GALA undergoes a conformational transition from random coil to α-helix in an acidic environment at pH 5.0, thereby inducing endosomal membrane destabilization and fusion. GALA-modified liposomes traverse lung endothelial cells via clathrin-dependent endocytosis and transcytosis, and specifically accumulate in the lungs after intravenous injection. DSPE-PEG2000-GALA can be used for drug delivery .
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- HY-172723
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Biochemical Assay Reagents
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DSPE-PEG2000-T7 is a PEGylated compound composed of DSPE and peptideT7. T7 (HAIYPRH) specifically binds to TfR. DSPE-PEG2000-T7 can be used to prepare T7-modified liposomes, where liposomes modified with both T7 and DA7R peptides can effectively co-deliver Doxorubicin (HY-15142A) and Vincristine (HY-N0488A) to gliomas. DSPE-PEG2000-T7 can also be used to prepare nanomodulators that mediate the co-delivery of tyrosine hydroxylase mRNA and interferon gene stimulator antagonists for synergistic intervention in Parkinson's disease .
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- HY-W440681
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Biochemical Assay Reagents
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C13-112-tri-tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tri-tail can be formulated into a lipid nanoparticle (LNP).
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- HY-W440683
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Biochemical Assay Reagents
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C13-112-tetra-tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tetra-tail can be formulated into a lipid nanoparticle (LNP).
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| Cat. No. |
Product Name |
Target |
Research Area |
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- HY-169089
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Drug Derivative
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Cancer
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RP-182-PEG3-K palmitic acid-NH2 (Compound 1a) is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K palmitic acid-NH2 inhibits CD206 high M2-like macrophage (IC50 of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K palmitic acid-NH2 exhibits antitumor efficacy in mouse B16 melanoma allografts .
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- HY-P11455A
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Liposome
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Others
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Lipopeptide CPE4 TFA is a PEG-modified peptide E4 [(EIAALEK) 4]. Lipopeptide CPE4 TFA is capable of coiled-coil formation when attached to liposomes. Lipopeptide CPE4 TFA triggers membrane fusion between liposomes and living cells with concomitant efficient cytosolic delivery of a variety of compounds such as fluorescent dyes Propidium Iodide (PI) (HY-D0815) and TO-PRO-3 iodide (HY-117070), and Doxorubicin (DOX) (HY-15142A). Lipopeptide CPE4 TFA can be used for drug delivery research .
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- HY-169089A
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Drug Derivative
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Cancer
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RP-182-PEG3-K(palmitic acid)-NH2 (Compound 1a) TFA is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K(palmitic acid)-NH2 TFA inhibits CD206 high M2-like macrophage (IC50 of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K(palmitic acid)-NH2 TFA exhibits antitumor efficacy in mouse B16 melanoma allografts .
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- HY-P11455
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Liposome
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Others
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Lipopeptide CPE4 is a PEG-modified peptide E4 [(EIAALEK) 4]. Lipopeptide CPE4 is capable of coiled-coil formation when attached to liposomes. Lipopeptide CPE4 triggers membrane fusion between liposomes and living cells with concomitant efficient cytosolic delivery of a variety of compounds such as fluorescent dyes Propidium Iodide (PI) (HY-D0815) and TO-PRO-3 iodide (HY-117070), and Doxorubicin (DOX) (HY-15142A). Lipopeptide CPE4 can be used for drug delivery research .
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- HY-P11485
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Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
PSMA
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Cancer
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JR11-PEG3-HBED-CC-PSMA-03 (Compound 1) is an RDC-related compound containing the chelating agent HBED-CC, the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-HBED-CC-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 59.2 nM, 57.0 nM, respectively. JR11-PEG3-HBED-CC-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-HBED-CC-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
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- HY-P11488
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Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
PSMA
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Cancer
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JR11-PEG3-DOTA-PSMA-03 (Compound 2) is an RDC-related compound containing the chelating agent DOTA (HY-W053583), the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-DOTA-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 94.0 nM, 81.8 nM, respectively. JR11-PEG3-DOTA-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-DOTA-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
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| Cat. No. |
Product Name |
|
Classification |
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- HY-160788
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DBCO
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DBCO-β-Glu-PEG12-Exatecan (Compound 107) is an inhibitor for topoisomerase I. DBCO-β-Glu-PEG12-Exatecan can be used as a Drug-Linker Conjugate for ADC molecule .
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- HY-164792
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DBCO
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|
DBCO-PEG3-VC-Exatecan (compound 25) is a Drug-Linker Conjugate for ADC. DBCO-PEG3-VC-Exatecan contains the ADC linker (DBCO-PEG3-VC) and a DNA topoisomerase I inhibitor Exatecan (HY-13631) .
|
-
- HY-W590569
-
|
|
|
Azide
|
|
Azido-PEG12-amine is a water soluble PEG compound. The azide group enables Click Chemistry. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The hydrophilic PEG arm increases solubility in aqueous media.
|
-
- HY-W591374
-
|
|
|
DBCO
|
|
DBCO-PEG4-Val-Ala-PAB-PNP is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. The DBCO groups is commonly used for Click Chemistry reactions. PEG spacer improves the compound's aqueous solubility. PNP is a good leaving group.
|
-
- HY-130182
-
|
|
|
ADC Synthesis
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG8-NH2 (compound 3b) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-NH2 is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG8-NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-131158
-
|
|
|
DBCO
|
|
DBCO-PEG3-Glu-VC-PABC-MMAF (compound s19b) is a drug-linker conjugate for ADC by using the tubulin inhibitor, MMAF (HY-15579), linked via cathepsin cleavable DBCO-PEG3-Glu-VC-PABC. DBCO-PEG3-Glu-VC-PABC-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130652
-
|
|
|
PROTAC Synthesis
Azide
|
|
Pomalidomide 4'-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a linker. Pomalidomide 4'-PEG3-azide can be used for the synthesis of iRucaparib-TP3 (Compound 3). iRucaparib-TP3 is a highly efficient PARP1?degrader based on Rucaparib by using the PROTAC approach . Pomalidomide 4'-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-156313
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Me-Tet-PEG4-NHS is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156379
-
-
- HY-W591272
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Me-Tet-PEG3-NH2 is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-NH2 can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups .
|
-
- HY-156308
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Me-Tet-PEG4-Maleimide is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-158199
-
|
|
|
BCN
|
|
BCN-HS-PEG2-bis(PNP) (Compound 62) is a p-nitrophenyl-containing ADC linker that can be used to further couple ADC cytotoxins with peptide linkers. BCN-HS-PEG2-bis(PNP) can conjugate with vc-PABC-MMAE (HY-15162) to form Drug-Linker Conjugates for ADC .
|
-
- HY-147192
-
|
|
|
Alkynes
|
|
(S,R,S)-AHPC-O-PEG1-propargyl (Compound 10b) is an E3 ligand for the synthesis of PROTAC . (S,R,S)-AHPC-O-PEG1-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-156493
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Me-Tet-PEG5-COOH is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-115414
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Bis-propargyl-PEG8 (compound 16e) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-propargyl-PEG8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-180447
-
|
|
|
Tetrazine
|
|
Tz-Ph-PEG4-NH-DOTA (Compound 10) is a 1,2,4,5-tetrazine (Tz) derivative. Tz-Ph-PEG4-NH-DOTA can be used in PET imaging and tumor research .
|
-
- HY-156307
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Me-Tet-PEG3-Maleimide is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-156312
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Me-Tet-PEG8-Maleimide is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-151758
-
|
|
|
Tetrazine
|
|
Methyltetrazine-PEG12-NHS ester is a click chemistry reagent containing an azide group. Methyltetrazine-PEG12-NHS ester reacts with compounds containing TCO to form stable covalent bonds .
|
-
- HY-156492
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Me-Tet-PEG4-COOH is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156494
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Me-Tet-PEG9-COOH is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156491
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Me-Tet-PEG9-NHS is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156475
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Me-Tet-PEG2-COOH is an ADC Linker containing 2 PEG units. Me-Tet-PEG2-COOH can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156495
-
|
|
|
Labeling and Fluorescence Imaging
Tetrazine
|
|
Biotin-PEG3-Me-Tet is an ADC Linker containing 3 PEG units. Biotin-PEG3-Me-Tet can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156479
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Me-Tet-PEG3-NHBoc is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156476
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Me-Tet-PEG2-NHS is an ADC Linker containing 2 PEG units. Me-Tet-PEG2-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156478
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Me-Tet-PEG4-NHBoc is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156477
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Me-Tet-PEG8-NHBoc is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156490
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Me-Tet-PEG5-NHS is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-161133
-
|
|
|
Azide
|
|
Lenalidomide 4'-PEG1-azide (Compound 4g) is a lenalidomide-derived azide. Lenalidomide 4'-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide 4'-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. .
|
-
- HY-156301A
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Me-Tet-PEG8-NH2 (hydrochloride) is an ADC Linker containing 2 PEG units. Me-Tet-PEG8-NH2 (hydrochloride) can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156300
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Me-Tet-PEG4-NH2 is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NH2 can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-W591373
-
|
|
|
DBCO
|
|
DBCO-PEG4-Val-Ala-PAB is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. The DBCO groups is commonly used for Click Chemistry reactions. PEG spacer improves the compound's aqueous solubility.
|
-
- HY-139332
-
|
|
|
Azide
|
|
Pomalidomide 4'-PEG6-azide (compound 33e) is the E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Pomalidomide 4'-alkylC3-acid can be used to synthesize PROTACs .
|
-
- HY-156301
-
|
|
|
Tetrazine
|
|
Methyltetrazine-amido-PEG8-amine Trifluoroacetate is a heterobifunctional linker containing a terminal methyltetrazine, which can react with TCO-containing compounds without the catalysis of Cu or elevated temperatures, and terminal amine, which reacts with NHS ester specifically and efficiently. The PEG spacer enhances water solubility.
|
-
- HY-130390
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
Propargyl-PEG4-O-C1-NHS ester (compound 8) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-O-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W800658
-
|
|
|
DBCO
|
|
DBCO-PEG6-NH-Boc is a click chemistry reagent with a DBCO group and a Boc-protected amine. The DBCO can undergo copper-free Click Chemistry reactions with azides. The Boc protecting group can be removed under acidic conditions. The hydrophilic PEG linker increases the water solubility of the compound.
|
-
- HY-151772
-
|
|
|
Tetrazine
|
|
Methyltetrazine-PEG12-t-butyl ester is a monodisperse PEG compound. Methyltetrazine-PEG12-t-butyl ester is a click chemistry reagent containing a tetrazine group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-151833
-
|
|
|
Tetrazine
|
|
Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent containing an azide group. Methyltetrazine-amido-N-bis(PEG4-acid) is a PEG derivative that contains a methyltetrazine group and two acid groups. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. PEG linker increases the water solubility of the compound. Reagent grade, for research use only . Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-W096068
-
|
|
|
Alkynes
|
|
Propargyl-PEG5-Ms represents a bifunctional linker possessing a proparygyl group reactive towards azides in copper (I) click chemistry to form stable triazoles with the target compound as well as a mesyl group which is a good leaving group for nucleophilic reactions.
|
-
- HY-130984
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG1-CH2COO-Cl (compound 43a) is an alkyl/ether-based PROTAC linker. Azido-PEG1-CH2COO-Cl can be used in the synthesis of PROTAC BRD4 Degrader-1 (HY-133131) . Azido-PEG1-CH2COO-Cl is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D1312
-
|
|
|
Azide
|
|
Pyrene azide 2 is a compound derived from pyreneacetic acid, connecting a fluorescent pyrene molecule by a PEG2 linker. The PEG units improve the water solubility of the compound.
|
-
- HY-181183
-
|
|
|
Alkynes
|
|
Propargyl-PEG24-acid (Compound 88) is an ADC linker, belonging to the PEG category, and can be used for the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-179193E
-
|
N3-PEG5000-OPSS
|
|
Azide
|
|
Azide-PEG5000-OPSS (N3-PEG5000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG5000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-179193C
-
|
N3-PEG2000-OPSS
|
|
Azide
|
|
Azide-PEG2000-OPSS (N3-PEG2000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG2000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-179193H
-
|
N3-PEG10000-OPSS
|
|
Azide
|
|
Azide-PEG10000-OPSS (N3-PEG10000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG10000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-179193B
-
|
N3-PEG1000-OPSS
|
|
Azide
|
|
Azide-PEG1000-OPSS (N3-PEG1000-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG1000-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-179193D
-
|
N3-PEG3400-OPSS
|
|
Azide
|
|
Azide-PEG3400-OPSS (N3-PEG3400-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG3400-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-179193A
-
|
N3-PEG600-OPSS
|
|
Azide
|
|
Azide-PEG600-OPSS (N3-PEG600-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG600-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-179193
-
|
N3-PEG400-OPSS
|
|
Azide
|
|
Azide-PEG400-OPSS (N3-PEG400-OPSS) is a compound composed of an azide group, PEG, and o-dithiopyridine (OPSS) and can be used for drug delivery. Azide-PEG400-OPSS is a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azido-yne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. It can also undergo ring-strain-driven acetylene-azidocycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-181043
-
|
|
|
Azide
|
|
CRBN ligand-895-PEG2-N3 (Compound 15) is a synthetic E3 ligase linker conjugate that can be used for the synthesis of PROTACs, such as PROTAC HDAC8 Degrader-4 (HY-181024) .
|
- HY-W190928
-
|
|
|
Azide
|
|
2-(Azido-PEG2-amido)-1,3-bis-(tert-butyldimethylsilanoxy)propane is a PEG linker containing a TBDMS acid labile, alcohol protecting group. The azide group is able to participate in copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN to generate triazole linkages. The hydrophilic PEG linker increases the solubility properties of compounds in aqueous media.
|
- HY-176947
-
|
|
|
Azide
|
|
Demethyl-sapanisertib-C2-amide-PEG7-C2-N3 (Compound 10c) is an azide group linker used for coupling, which can be employed in the synthesis of "Rapa-Link" compounds, such as M-1111 (HY-176948), an mTOR inhibitor .
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-172696
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG2000-WYRGRL can be used for drug delivery .
|
-
- HY-177203
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-APWHLSSQYSRT is a PEG compound which composed of DSPE and 12-amino acid cardiac targeting peptide (APWHLSSQYSRT). DSPE-PEG2000-APWHLSSQYSRT can be used for drug delivery .
|
-
- HY-172277A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG2000-R9 can be used for drug delivery .
|
-
- HY-172275A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG2000-pPB can be used for drug delivery .
|
-
- HY-172279
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-TAT is a PEG compound which composed of DSPE and a cell-penetrating peptide (TAT) (HY-P0281). DSPE-PEG1000-TAT can be used for drug delivery .
|
-
- HY-172279C
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-TAT is a PEG compound which composed of DSPE and a cell-penetrating peptide (TAT) (HY-P0281). DSPE-PEG3400-TAT can be used for drug delivery .
|
-
- HY-172699A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG3400-ANG can be used for drug delivery .
|
-
- HY-172687
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). DSPE-PEG2000-CSTSMLKAC can be used for drug delivery DSPE-PEG2000-CSTSMLKAC enables targeted delivery of associated nanoliposomes to ischemic myocardial cells .
|
-
- HY-172691
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .
|
-
- HY-172690
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .
|
-
- HY-172473
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG2000-NGR can be used for drug delivery .
|
-
- HY-172278A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG2000-CGKRK can be used for drug delivery .
|
-
- HY-172279B
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-TAT is a PEG compound which composed of DSPE and a cell-penetrating peptide (TAT) (HY-P0281). DSPE-PEG5000-TAT can be used for drug delivery .
|
-
- HY-172276A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG2000-R8 can be used for drug delivery .
|
-
- HY-W1048669B
-
|
|
|
Pegylated Lipids
|
|
Biotin-PEG10000-DMG is a compound composed of biotin, PEG, and myristoyl-sn-glycerol, used for drug delivery. Biotin forms a stable non-covalent bond with streptavidin.
|
-
- HY-172497
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG2000-CREKA can be used for drug delivery .
|
-
- HY-172470A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-GE11 is a PEG compound which composed of DSPE and an EGFR targeting peptide (GE11). GE11 can be used for EGFR overexpressed cancer cells. DSPE-PEG3400-GE11 can be used for drug delivery .
|
-
- HY-172274A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-APRPG is a PEG compound which composed of DSPE and a APRPG peptide. DSPE-PEG2000-APRPG can be used for drug delivery .
|
-
- HY-172278C
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG3400-CGKRK can be used for drug delivery .
|
-
- HY-172278B
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG5000-CGKRK can be used for drug delivery .
|
-
- HY-172278
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG1000-CGKRK can be used for drug delivery .
|
-
- HY-172681
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG2000-VIP can be used for drug delivery .
|
-
- HY-172682
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG5000-VIP can be used for drug delivery .
|
-
- HY-172681A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG3400-VIP can be used for drug delivery .
|
-
- HY-172276C
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG3400-R8 can be used for drug delivery .
|
-
- HY-172276B
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG5000-R8 can be used for drug delivery .
|
-
- HY-172482A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG3400-TAASGVRSMH can be used for drug delivery .
|
-
- HY-172277B
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG5000-R9 can be used for drug delivery .
|
-
- HY-172687A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). CSTSMLKAC is capable of mediating selective homing of phage to ischemic heart tissue. DSPE-PEG3400-CSTSMLKAC can be used for drug delivery .
|
-
- HY-172726
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG2000-EB1 can be used for drug delivery .
|
-
- HY-172726A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG3400-EB1 can be used for drug delivery .
|
-
- HY-172688
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). CSTSMLKAC is capable of mediating selective homing of phage to ischemic heart tissue. DSPE-PEG5000-CSTSMLKAC can be used for drug delivery .
|
-
- HY-172277C
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG3400-R9 can be used for drug delivery .
|
-
- HY-172277
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG1000-R9 can be used for drug delivery .
|
-
- HY-172708A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG3400-PP1 can be used for drug delivery .
|
-
- HY-172473A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG34000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG3400-NGR can be used for drug delivery .
|
-
- HY-172503A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG3400-KAA can be used for drug delivery .
|
-
- HY-172685
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG5000-GRGDS can be used for drug delivery .
|
-
- HY-172684A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG3400-GRGDS can be used for drug delivery .
|
-
- HY-172684
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG2000-GRGDS can be used for drug delivery .
|
-
- HY-172503
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG2000-KAA can be used for drug delivery .
|
-
- HY-172708
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG2000-PP1 can be used for drug delivery .
|
-
- HY-172496
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG1000-CREKA can be used for drug delivery .
|
-
- HY-172696A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG3400-WYRGRL can be used for drug delivery .
|
-
- HY-172702A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG3400-NYZL1 can be used for drug delivery .
|
-
- HY-172498
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG5000-CREKA can be used for drug delivery .
|
-
- HY-172497A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG3400-CREKA can be used for drug delivery .
|
-
- HY-172697
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG5000-WYRGRL can be used for drug delivery .
|
-
- HY-172466
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-CTT2 is a PEG compound which composed of DSPE and a gelatinase inhibitor (CTT2 (CTTHWGFTLC)). CTT2 (CTTHWGFTLC) has the ability to specifically target tumors. DSPE-PEG1000-CTT2 can be used for drug delivery .
|
-
- HY-172471
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-GE11 is a PEG compound which composed of DSPE and an EGFR targeting peptide (GE11). GE11 can be used for EGFR overexpressed cancer cells. DSPE-PEG5000-GE11 can be used for drug delivery .
|
- HY-172484
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG1000-LTLRWVGLMS can be used for drug delivery .
|
- HY-172469
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-GE11 is a PEG compound which composed of DSPE and an EGFR targeting peptide (GE11). GE11 can be used for EGFR overexpressed cancer cells. DSPE-PEG1000-GE11 can be used for drug delivery .
|
- HY-172275B
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG5000-pPB can be used for drug delivery .
|
- HY-172485
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG2000-LTLRWVGLMS can be used for drug delivery .
|
- HY-172723A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG3400-T7 can be used for drug delivery .
|
- HY-172724
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG5000-T7 can be used for drug delivery .
|
- HY-172722
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG1000-T7 can be used for drug delivery .
|
- HY-172492
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-ESBP is a PEG compound which composed of DSPE and a E-selectin-binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells .
|
- HY-172280A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG21000-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG2000-Octreotide can be used for drug delivery .
|
- HY-172280C
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG3400-Octreotide can be used for drug delivery .
|
- HY-172700
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG5000-ANG can be used for drug delivery .
|
- HY-172280B
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG5000-Octreotide can be used for drug delivery .
|
- HY-172274
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-APRPG is a PEG compound which composed of DSPE and a APRPG peptide. DSPE-PEG1000-APRPG can be used for drug delivery .
|
- HY-172274B
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-APRPG is a PEG compound which composed of DSPE and a APRPG peptide. DSPE-PEG5000-APRPG can be used for drug delivery .
|
- HY-172680
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG1000-VIP can be used for drug delivery .
|
- HY-172276
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG1000-R8 can be used for drug delivery .
|
- HY-172483
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3000-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG3000-TAASGVRSMH can be used for drug delivery .
|
- HY-172481
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG1000-TAASGVRSMH can be used for drug delivery .
|
- HY-172482
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG2000-TAASGVRSMH can be used for drug delivery .
|
- HY-W1048669A
-
|
|
|
Pegylated Lipids
|
|
Biotin-PEG5000-DMG is a compound composed of biotin, PEG, and myristoyl-sn-glycerol, used for drug delivery. Biotin forms a stable non-covalent bond with streptavidin.
|
- HY-W1048669I
-
|
|
|
Pegylated Lipids
|
|
Biotin-PEG3400-DMG is a compound composed of biotin, PEG, and myristoyl-sn-glycerol, used for drug delivery. Biotin forms a stable non-covalent bond with streptavidin.
|
- HY-W1048669H
-
|
|
|
Pegylated Lipids
|
|
Biotin-PEG2000-DMG is a compound composed of biotin, PEG, and myristoyl-sn-glycerol, used for drug delivery. Biotin forms a stable non-covalent bond with streptavidin.
|
- HY-W1048669E
-
|
|
|
Pegylated Lipids
|
|
Biotin-PEG1000-DMG is a compound composed of biotin, PEG, and myristoyl-sn-glycerol, used for drug delivery. Biotin forms a stable non-covalent bond with streptavidin.
|
- HY-172727
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG5000-EB1 can be used for drug delivery .
|
- HY-172686
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). CSTSMLKAC is capable of mediating selective homing of phage to ischemic heart tissue. DSPE-PEG1000-CSTSMLKAC can be used for drug delivery .
|
- HY-172725
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG1000-EB1 can be used for drug delivery .
|
- HY-172689
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .
|
- HY-172504
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG5000-KAA can be used for drug delivery .
|
- HY-172474
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG5000-NGR can be used for drug delivery .
|
- HY-172502
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG1000-KAA can be used for drug delivery .
|
- HY-172709
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG5000-PP1 can be used for drug delivery .
|
- HY-172472
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG1000-NGR can be used for drug delivery .
|
- HY-172683
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG1000-GRGDS can be used for drug delivery .
|
- HY-172707
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG1000-PP1 can be used for drug delivery .
|
- HY-172701
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG1000-NYZL1 can be used for drug delivery .
|
- HY-172695
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG1000-WYRGRL can be used for drug delivery .
|
- HY-172702
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG2000-NYZL1 can be used for drug delivery .
|
- HY-172703
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG5000-NYZL1 can be used for drug delivery .
|
- HY-172467
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-CTT2 is a PEG compound which composed of DSPE and a gelatinase inhibitor (CTT2 (CTTHWGFTLC)). CTT2 (CTTHWGFTLC) has the ability to specifically target tumors. DSPE-PEG2000-CTT2 can be used for drug delivery .
|
- HY-172468
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-CTT2 is a PEG compound which composed of DSPE and a gelatinase inhibitor (CTT2 (CTTHWGFTLC)). CTT2 (CTTHWGFTLC) has the ability to specifically target tumors. DSPE-PEG5000-CTT2 can be used for drug delivery .
|
- HY-172485A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG3400-LTLRWVGLMS can be used for drug delivery .
|
- HY-172486
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG5000-LTLRWVGLMS can be used for drug delivery .
|
- HY-172275
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG1000-pPB can be used for drug delivery .
|
- HY-172275C
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG3400-pPB can be used for drug delivery .
|
- HY-171728
-
|
|
|
Pegylated Lipids
|
|
Azide-PEG2-amide-C14-COOH (Compound LP-379-p) is a lipid-containing compound. Azide-PEG2-amide-C14-COOH facilitates the delivery of oligonucleotide-based reagents to certain cell types or adipose tissue .
|
- HY-172491
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-ESBP is a PEG compound which composed of DSPE and a E-selectin-binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells .
|
- HY-172490
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-ESBP is a PEG compound which composed of DSPE and a E-selectin-binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells .
|
- HY-172280
-
|
|
|
Pegylated Lipids
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DSPE-PEG1000-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG1000-Octreotide can be used for drug delivery .
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- HY-172281B
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Pegylated Lipids
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DSPE-PEG5000-CCK8 is a PEG compound which composed of DSPE and a Cholecystokinin-8 (CCK8). Cholecystokinin-8 has the activity of peptide regulating gallbladder contraction and digestive system function. DSPE-PEG5000-CCK8 can be used for drug delivery .
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- HY-172698
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Pegylated Lipids
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DSPE-PEG1000-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG1000-ANG can be used for drug delivery .
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- HY-172464
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Pegylated Lipids
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DSPE-PEG2000-cRGD is a PEG compound which composed of DSPE and an αvβ3 targeting peptide (cRGD). cRGD peptide can specifically bind to αvβ3 on the surface of many cancer cells and neovascular cells. DSPE-PEG2000-cRGD can be used for drug delivery .
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- HY-172464A
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Pegylated Lipids
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DSPE-PEG3400-cRGD is a PEG compound which composed of DSPE and an αvβ3 targeting peptide (cRGD). cRGD peptide can specifically bind to αvβ3 on the surface of many cancer cells and neovascular cells. DSPE-PEG3400-cRGD can be used for drug delivery .
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- HY-172463
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Pegylated Lipids
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DSPE-PEG1000-cRGD is a PEG compound which composed of DSPE and an αvβ3 targeting peptide (cRGD). cRGD peptide can specifically bind to αvβ3 on the surface of many cancer cells and neovascular cells. DSPE-PEG1000-cRGD can be used for drug delivery .
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- HY-W440891
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Pegylated Lipids
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DSPE-PEG1000-OH is a hydroxyl terminated phospholipid PEG polymer. The hydrophobic tails allow for the encapsulation and congregation of other hydrophobic drugs. The polymer can be used to prepare liposomes or lipid nanoparticles. Hydroxyl terminal can further derivatize the compound.
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- HY-172477
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Pegylated Lipids
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DSPE-PEG5000-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG5000-YIGSR can be used for drug delivery .
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- HY-172479
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Pegylated Lipids
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DSPE-PEG2000-F3 is a PEG compound which composed of DSPE and a nucleolin targeting peptide (F3). F3 peptide can specifically bind to cell surface nucleolin and undergo an effective cell surface to nucleus transport. DSPE-PEG2000-F3 can be used for drug delivery .
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- HY-172479A
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Pegylated Lipids
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DSPE-PEG3400-F3 is a PEG compound which composed of DSPE and a nucleolin targeting peptide (F3). F3 peptide can specifically bind to cell surface nucleolin and undergo an effective cell surface to nucleus transport. DSPE-PEG3400-F3 can be used for drug delivery .
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- HY-172475
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Pegylated Lipids
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DSPE-PEG1000-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG1000-YIGSR can be used for drug delivery .
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- HY-172478
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Pegylated Lipids
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DSPE-PEG1000-F3 is a PEG compound which composed of DSPE and a nucleolin targeting peptide (F3). F3 peptide can specifically bind to cell surface nucleolin and undergo an effective cell surface to nucleus transport. DSPE-PEG1000-F3 can be used for drug delivery .
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- HY-172480
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Pegylated Lipids
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DSPE-PEG5000-F3 is a PEG compound which composed of DSPE and a nucleolin targeting peptide (F3). F3 peptide can specifically bind to cell surface nucleolin and undergo an effective cell surface to nucleus transport. DSPE-PEG5000-F3 can be used for drug delivery .
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- HY-172476
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Pegylated Lipids
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DSPE-PEG2000-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG2000-YIGSR can be used for drug delivery .
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- HY-172476A
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Pegylated Lipids
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DSPE-PEG3400-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG3400-YIGSR can be used for drug delivery .
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- HY-172692
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Pegylated Lipids
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DSPE-PEG1000-TH is a PEG compound which composed of DSPE and a pH-responsive cell penetrating peptide (TH). TH is activated in an acidic environment (such as the tumor microenvironment) and can selectively carry small molecules, oligonucleotides, proteins, etc. into tumor cells .
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- HY-172694
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Pegylated Lipids
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DSPE-PEG5000-TH is a PEG compound which composed of DSPE and a pH-responsive cell penetrating peptide (TH). TH is activated in an acidic environment (such as the tumor microenvironment) and can selectively carry small molecules, oligonucleotides, proteins, etc. into tumor cells .
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- HY-172693
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Pegylated Lipids
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DSPE-PEG2000-TH is a PEG compound which composed of DSPE and a pH-responsive cell penetrating peptide (TH). TH is activated in an acidic environment (such as the tumor microenvironment) and can selectively carry small molecules, oligonucleotides, proteins, etc. into tumor cells .
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- HY-172499
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Pegylated Lipids
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DSPE-PEG1000-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG1000-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.
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- HY-172495
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Pegylated Lipids
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DSPE-PEG3000-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG3000-iRGD can be used for drug delivery .
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- HY-172493
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Pegylated Lipids
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DSPE-PEG1000-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG1000-iRGD can be used for drug delivery .
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- HY-172494
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Pegylated Lipids
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DSPE-PEG2000-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG2000-iRGD can be used for agent delivery .
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- HY-172501
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Pegylated Lipids
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DSPE-PEG5000-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG5000-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.
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- HY-172494A
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Pegylated Lipids
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DSPE-PEG3400-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG3400-iRGD can be used for drug delivery .
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- HY-172500
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Pegylated Lipids
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DSPE-PEG2000-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG2000-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.
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- HY-172706
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Pegylated Lipids
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DSPE-PEG5000-RVG29 is a PEG compound which composed of DSPE and a Rabies virus glycoprotein 29 (RVG29). RVG29 can bind specifically to the nicotinic acetylcholine receptor (nAChR) at the blood-brain barrier (BBB) and cross over the BBB .
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- HY-172272B
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Pegylated Lipids
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DSPE-PEG5000-A7R is a PEG compound which composed of DSPE and a tumor vascular targeting peptide (A7R). A7R exhibits high affinity and specificity for VEGFR-2, which is overexpressed in various tumors .
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- HY-172272A
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Pegylated Lipids
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DSPE-PEG2000-A7R is a PEG compound which composed of DSPE and a tumor vascular targeting peptide (A7R). A7R exhibits high affinity and specificity for VEGFR-2, which is overexpressed in various tumors .
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- HY-172704
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Pegylated Lipids
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DSPE-PEG1000-RVG29 is a PEG compound which composed of DSPE and a Rabies virus glycoprotein 29 (RVG29). RVG29 can bind specifically to the nicotinic acetylcholine receptor (nAChR) at the blood-brain barrier (BBB) and cross over the BBB .
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- HY-172272
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Pegylated Lipids
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DSPE-PEG1000-A7R is a PEG compound which composed of DSPE and a tumor vascular targeting peptide (A7R). A7R exhibits high affinity and specificity for VEGFR-2, which is overexpressed in various tumors .
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- HY-172488A
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Pegylated Lipids
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DSPE-PEG3400-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG3400-K237 can be used for drug delivery .
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- HY-172489
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Pegylated Lipids
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DSPE-PEG5000-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG5000-K237 can be used for drug delivery .
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- HY-172488
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Pegylated Lipids
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DSPE-PEG2000-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG2000-K237 can be used for drug delivery .
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- HY-172487
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Pegylated Lipids
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DSPE-PEG1000-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG1000-K237 can be used for drug delivery .
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- HY-172283A
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Pegylated Lipids
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DSPE-PEG2000-BR2 is a PEG compound which composed of DSPE and a BR2. BR2 is a targeting peptide composed of 17 amino acids with the sequence RAGLQFPVGRLLRRLLR. It has the ability to assist cells to penetrate the membrane and can specifically target certain cells or tissues .
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- HY-172283
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Pegylated Lipids
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DSPE-PEG1000-BR2 is a PEG compound which composed of DSPE and a BR2. BR2 is a targeting peptide composed of 17 amino acids with the sequence RAGLQFPVGRLLRRLLR. It has the ability to assist cells to penetrate the membrane and can specifically target certain cells or tissues .
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- HY-172283B
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Pegylated Lipids
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DSPE-PEG5000-BR2 is a PEG compound which composed of DSPE and a BR2. BR2 is a targeting peptide composed of 17 amino acids with the sequence RAGLQFPVGRLLRRLLR. It has the ability to assist cells to penetrate the membrane and can specifically target certain cells or tissues .
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- HY-172711A
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Pegylated Lipids
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DSPE-PEG3400-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG3400-R6H4 can be used for drug delivery .
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- HY-172273B
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Pegylated Lipids
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DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .
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- HY-172273A
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Pegylated Lipids
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DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .
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- HY-172273
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Pegylated Lipids
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DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .
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- HY-172711
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Pegylated Lipids
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|
DSPE-PEG2000-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG2000-R6H4 can be used for drug delivery .
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- HY-172712
-
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Pegylated Lipids
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DSPE-PEG3000-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG3000-R6H4 can be used for drug delivery .
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- HY-172710
-
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Pegylated Lipids
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DSPE-PEG1000-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG1000-R6H4 can be used for drug delivery .
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- HY-172273C
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Pegylated Lipids
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DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .
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- HY-172271A
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Pegylated Lipids
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DSPE-PEG2000-LyP-1 is a PEG compound which composed of DSPE and a nine residue peptide (LyP-1) (HY-P2526). LyP-1 is a cyclic 9-amino-acids tumor homing peptide and selectively bind to p32 receptors overexpressed in various tumor-associated cells .
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- HY-172271B
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Pegylated Lipids
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DSPE-PEG3000-LyP-1 is a PEG compound which composed of DSPE and a nine residue peptide (LyP-1) (HY-P2526). LyP-1 is a cyclic 9-amino-acids tumor homing peptide and selectively bind to p32 receptors overexpressed in various tumor-associated cells .
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- HY-172714
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Pegylated Lipids
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DSPE-PEG2000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
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- HY-172713
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Pegylated Lipids
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DSPE-PEG1000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
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- HY-W591332
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Pegylated Lipids
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mPEG2000-DMPE is a PEGylated 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE) compound with a methyl group at the other end of the PEG chain. The PEG polymer exhibits amphiphatic behavior and helps to form stable micelles in an aqueous solution. It can be used to prepare nanoparticles or liposomes for targeted drug delivery applications.
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- HY-172715
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Pegylated Lipids
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DSPE-PEG5000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
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- HY-172271
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Pegylated Lipids
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|
DSPE-PEG1000-Mal-Cys-CGNKRTRGC (Disulfide bridge: Cys2-Cys10) is a PEG compound which composed of DSPE and a nine residue peptide (LyP-1) (HY-P2526). LyP-1 is a cyclic 9-amino-acids tumor homing peptide and selectively bind to p32 receptors overexpressed in various tumor-associated cells .
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- HY-172723
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Pegylated Lipids
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DSPE-PEG2000-T7 is a PEGylated compound composed of DSPE and peptideT7. T7 (HAIYPRH) specifically binds to TfR. DSPE-PEG2000-T7 can be used to prepare T7-modified liposomes, where liposomes modified with both T7 and DA7R peptides can effectively co-deliver Doxorubicin (HY-15142A) and Vincristine (HY-N0488A) to gliomas. DSPE-PEG2000-T7 can also be used to prepare nanomodulators that mediate the co-delivery of tyrosine hydroxylase mRNA and interferon gene stimulator antagonists for synergistic intervention in Parkinson's disease .
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- HY-W440681
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Cationic Lipids
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C13-112-tri-tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tri-tail can be formulated into a lipid nanoparticle (LNP).
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- HY-W440683
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Cationic Lipids
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C13-112-tetra-tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tetra-tail can be formulated into a lipid nanoparticle (LNP).
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