2. Search Result
Search Result
Results for "

PEP1

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

13

Peptides

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P5366
    PEP1

    		Liposome Others
    PEP1 is an amphipathic α-helical peptide containing 31 residues. The interaction of PEP1 with POPC-supported lipid bilayers (SLBs) is concentration-dependent: at low concentrations, it inserts into SLBs to generate compressive stress; at medium concentrations, it saturates the membrane surface to maintain constant stress; and at high concentrations, it solubilizes SLBs. PEP1 can be used for research on the mechanism of membrane-peptide interactions [1] .
    PEP1
  • HY-P1848
    Pep-1 (uncapped)
    2 Publications Verification

    		 Interleukin Related Cancer
    Pep-1 (uncapped) is a specific ligand of IL-13Ra2. Pep-1 (uncapped) exerts cell penetrating activity through receptor-mediated endocytosis, can cross the blood-tumor barrier (BTB) and target glioma cells. Pep-1 (uncapped) can enhance the uptake of nanoparticles by tumor cells and enhance the cell penetration ability of nanoparticles, and can be used to develop targeted drug delivery systems for glioma [1].
    Pep-1 (uncapped)
  • HY-P11287A
    DOTA-Pep-1L TFA

    		Interleukin Related Radionuclide-Drug Conjugates (RDCs) Cancer
    DOTA-Pep-1L TFA is a polypeptide formed by the conjugation of DOTA and Pep-1L. DOTA-Pep-1L TFA specifically binds to IL13RA2 and can be used for the synthesis of targeted polypeptides. DOTA-Pep-1L TFA yields the isotopically labeled product [ 225Ac]DOTA-Pep-1L, which exerts α-radiation killing effects on orthotopic glioma cells and extends the median survival time of mice bearing orthotopic glioma models after stereotactic injection. DOTA-Pep-1L TFA can be used for PET imaging, tumor targeting and glioma research [1] .
    DOTA-Pep-1L TFA
  • HY-P4490
    Suc-Ala-Pro-pNA
    1 Publications Verification

    		 Prolyl Endopeptidase (PREP) Others
    Suc-Ala-Pro-pNA is a peptide that serves as a substrate to detect the activity and stability of prolyl endopeptidase (PEP) .
    Suc-Ala-Pro-pNA
  • HY-P10292
    NOTA-Pep-1L

    		Radionuclide-Drug Conjugates (RDCs) Interleukin Related Cancer
    NOTA-Pep-1L specifically targets the IL13RA2 receptor for tumor imaging [1]. NOTA-Pep-1L can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
    NOTA-Pep-1L
  • HY-P4119
    Pep-1-Cysteamine

    		Biochemical Assay Reagents Others
    Pep-1-Cysteamine is an amphipathic chimeric cell-penetrating peptide. Pep-1-Cysteamine can penetrate biological membranes in an energy-independent manner without forming transmembrane pores, and efficiently deliver active proteins into cells, with its translocation dominated by electrostatic interactions and membrane perturbation [1].
    Pep-1-Cysteamine
  • HY-P11287
    DOTA-Pep-1L

    		Interleukin Related Radionuclide-Drug Conjugates (RDCs) Cancer
    DOTA-Pep-1L is a polypeptide formed by the conjugation of DOTA and Pep-1L. DOTA-Pep-1L specifically binds to IL13RA2 and can be used for the synthesis of targeted polypeptides. DOTA-Pep-1L yields the isotopically labeled product [ 225Ac]DOTA-Pep-1L, which exerts α-radiation killing effects on orthotopic glioma cells and extends the median survival time of mice bearing orthotopic glioma models after stereotactic injection. DOTA-Pep-1L can be used for PET imaging, tumor targeting and glioma research [1] .
    DOTA-Pep-1L
  • HY-P10870
    Pep1-DNP conjugate 9

    		Peptide-Drug Conjugates (PDCs) FGFR Apoptosis Cancer
    Pep1-DNP conjugate 9 is a functionalized peptide which is composed of the DNP-Hapten and the FGFR1 binding peptide. Pep1-DNP conjugate 9 exhibits good affinity to FGFR1 with KD of 5.01 μM. Pep1-DNP conjugate 9 recruits anti-DNP antibodies to the surface of FGFR1-positive cells, inhibits the FGF2-induced proliferation in rat skeletal myoblast cells, and induces apoptosis. Pep1-DNP conjugate 9 exhibits antitumor efficacy in mouse models [1].
    Pep1-DNP conjugate 9
  • HY-P5352
    Hyaluronan-IN-1

    		CD44 Inflammation/Immunology Cancer
    Hyaluronan-IN-1 (Pep-1) is a Hyaluronan inhibitor with a Kd value of 1.65 μM. Hyaluronan-IN-1 blocks CD44-dependent cell adhesion. Hyaluronan-IN-1 inhibits cell adhesion to hyaluronan substrates. Hyaluronan-IN-1 suppresses the development of contact hypersensitivity in mice by blocking the homing process of inflammatory cells to the skin. Hyaluronan-IN-1 also inhibits responses during the sensitization phase. Hyaluronan-IN-1 reduces lung metastasis of melanoma and prolongs the survival of mice. Hyaluronan-IN-1 can be used in research related to contact hypersensitivity, chronic skin inflammation, and melanoma [1] .
    Hyaluronan-IN-1
  • HY-P1364
    Pep1-AGL

    		iGluR Neurological Disease
    Pep1-AGL is a peptide with the sequence of SSGMPLGAAGL. Pep1-AGL serves as the control peptide for Pep1-TGL (HY-P1367) [1].
    Pep1-AGL
  • HY-RS18385
    Cndp2 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Cndp2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cndp2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Cndp2 Mouse Pre-designed siRNA Set A
    Cndp2 Mouse Pre-designed siRNA Set A
  • HY-P11479
    Cbl-b-IN-31

    		E1/E2/E3 Enzyme Inflammation/Immunology
    Cbl-b-IN-31 (Compound Pep 1) is a Cbl-b inhibitor with a Kd of 0.42 μM. Cbl-b-IN-31 is inactive in cellular assays. Cbl-b-IN-31 can be used in the research of immune-mediated diseases [1].
    Cbl-b-IN-31

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: