14 Results for "

PEP1

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "PEP1" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P1848
CAS No.: 395069-86-0
Target:  

Interleukin Related

Research Areas:  

Cancer

Pep-1 (uncapped) is a specific ligand of IL-13Ra2. Pep-1 (uncapped) exerts cell penetrating activity through receptor-mediated endocytosis, can cross the blood-tumor barrier (BTB) and target glioma cells. Pep-1 (uncapped) can enhance the uptake of nanoparticles by tumor cells and enhance the cell penetration ability of nanoparticles, and can be used to develop targeted drug delivery systems for glioma [1].
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P4490
CAS No.: 95632-46-5
Research Areas:  

Others

Suc-Ala-Pro-pNA is a peptide that serves as a substrate to detect the activity and stability of prolyl endopeptidase (PEP) .
loading...
    loading...
Cat. No.: HY-P5366
Target:  

Liposome

Research Areas:  

Others

PEP1 is an amphipathic α-helical peptide containing 31 residues. The interaction of PEP1 with POPC-supported lipid bilayers (SLBs) is concentration-dependent: at low concentrations, it inserts into SLBs to generate compressive stress; at medium concentrations, it saturates the membrane surface to maintain constant stress; and at high concentrations, it solubilizes SLBs. PEP1 can be used for research on the mechanism of membrane-peptide interactions [1] .
loading...
    loading...
Cat. No.: HY-P11287A
DOTA-Pep-1L TFA is a polypeptide formed by the conjugation of DOTA and Pep-1L. DOTA-Pep-1L TFA specifically binds to IL13RA2 and can be used for the synthesis of targeted polypeptides. DOTA-Pep-1L TFA yields the isotopically labeled product [ 225Ac]DOTA-Pep-1L, which exerts α-radiation killing effects on orthotopic glioma cells and extends the median survival time of mice bearing orthotopic glioma models after stereotactic injection. DOTA-Pep-1L TFA can be used for PET imaging, tumor targeting and glioma research [1] .
loading...
    loading...
Cat. No.: HY-P10292
NOTA-Pep-1L specifically targets the IL13RA2 receptor for tumor imaging [1]. NOTA-Pep-1L can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
loading...
    loading...
Cat. No.: HY-P4119
CAS No.: 863608-35-9
Research Areas:  

Others

Pep-1-Cysteamine is an amphipathic chimeric cell-penetrating peptide. Pep-1-Cysteamine can penetrate biological membranes in an energy-independent manner without forming transmembrane pores, and efficiently deliver active proteins into cells, with its translocation dominated by electrostatic interactions and membrane perturbation [1].
loading...
    loading...
Cat. No.: HY-P11287
DOTA-Pep-1L is a polypeptide formed by the conjugation of DOTA and Pep-1L. DOTA-Pep-1L specifically binds to IL13RA2 and can be used for the synthesis of targeted polypeptides. DOTA-Pep-1L yields the isotopically labeled product [ 225Ac]DOTA-Pep-1L, which exerts α-radiation killing effects on orthotopic glioma cells and extends the median survival time of mice bearing orthotopic glioma models after stereotactic injection. DOTA-Pep-1L can be used for PET imaging, tumor targeting and glioma research [1] .
loading...
    loading...
Cat. No.: HY-P10870
Research Areas:  

Cancer

Pep1-DNP conjugate 9 is a functionalized peptide which is composed of the DNP-Hapten and the FGFR1 binding peptide. Pep1-DNP conjugate 9 exhibits good affinity to FGFR1 with KD of 5.01 μM. Pep1-DNP conjugate 9 recruits anti-DNP antibodies to the surface of FGFR1-positive cells, inhibits the FGF2-induced proliferation in rat skeletal myoblast cells, and induces apoptosis. Pep1-DNP conjugate 9 exhibits antitumor efficacy in mouse models [1].
loading...
    loading...
Cat. No.: HY-P4119A
Target:  

Peptides

Research Areas:  

Others

Pep-1-Cysteamine TFA is a chimeric cell-penetrating peptide (CPP) with a primary amphipathicity. Pep-1-Cysteamine TFA has the ability to translocate across biological membranes and introduce active proteins inside cells [1].
loading...
    loading...
Cat. No.: HY-P1367
Target:  

Peptides

Research Areas:  

Neurological Disease

Pep1-TGL is a synthetic peptide containing the TGL motif from the C-terminus of the AMPA receptor GluA1 subunit [1].
loading...
    loading...
Cat. No.: HY-P5352
CAS No.: 299157-43-0
Target:  

CD44

Research Areas:  

Inflammation/Immunology Cancer

Hyaluronan-IN-1 (Pep-1) is a Hyaluronan inhibitor with a Kd value of 1.65 μM. Hyaluronan-IN-1 blocks CD44-dependent cell adhesion. Hyaluronan-IN-1 inhibits cell adhesion to hyaluronan substrates. Hyaluronan-IN-1 suppresses the development of contact hypersensitivity in mice by blocking the homing process of inflammatory cells to the skin. Hyaluronan-IN-1 also inhibits responses during the sensitization phase. Hyaluronan-IN-1 reduces lung metastasis of melanoma and prolongs the survival of mice. Hyaluronan-IN-1 can be used in research related to contact hypersensitivity, chronic skin inflammation, and melanoma [1] .
loading...
    loading...
Cat. No.: HY-P1364
Target:  

iGluR

Research Areas:  

Neurological Disease

Pep1-AGL is a peptide with the sequence of SSGMPLGAAGL. Pep1-AGL serves as the control peptide for Pep1-TGL (HY-P1367) [1].
loading...
    loading...
Cat. No.: HY-RS18385
Research Areas:  

Others

Cndp2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cndp2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-P11479
CAS No.: 3029912-63-5
Target:  

E1/E2/E3 Enzyme

Research Areas:  

Inflammation/Immunology

Cbl-b-IN-31 (Compound Pep 1) is a Cbl-b inhibitor with a Kd of 0.42 μM. Cbl-b-IN-31 is inactive in cellular assays. Cbl-b-IN-31 can be used in the research of immune-mediated diseases [1].
loading...
    loading...
  • 1