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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
PTPN9
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "PTPN9" in MCE Product Catalog:
7
7 Cited Publications
Synonyms: ABBV-CLS-484
Target:
Research Areas:
Osunprotafib (ABBV-CLS-484) is an orally active and selective active site PTPN1 (IC50: 2.5 nM) and PTPN2(IC50: 1.8 nM) inhibitor. Osunprotafib has 6-8-fold weaker activity on PTPN9 and no detectable activity on SHP-1 or SHP-2. Osunprotafib increases the sensitivity of human cancer cell lines to IFNγ. Osunprotafib generates robust anti-tumor immunity by enhancing JAK-STAT signalling and reducing T cell dysfunction .
1
Category:
Flavonols Flavonoids Erythrina melanacantha Taub. ex Harms Phenols Polyphenols Plants Compositae Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-RS11431
Target:
Research Areas:
PTPN9 Human Pre-designed siRNA Set A contains three designed siRNAs for PTPN9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20474
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Research Areas:
Ptpn9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ptpn9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26982
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Research Areas:
Ptpn9 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ptpn9 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-145923B
CAS No.: 2986745-48-4
Synonyms: ABBV-CLS-484 hydrochloride
Target:
Research Areas:
Osunprotafib (ABBV-CLS-484) hydrochloride is an orally active and selective active site PTPN1 (IC50: 2.5 nM) and PTPN2(IC50: 1.8 nM) inhibitor. Osunprotafib hydrochloride has 6-8-fold weaker activity on PTPN9 and no detectable activity on SHP-1 or SHP-2. Osunprotafib hydrochloride increases the sensitivity of human cancer cell lines to IFNγ. Osunprotafib hydrochloride generates robust anti-tumor immunity by enhancing JAK-STAT signalling and reducing T cell dysfunction .
Cat. No.: HY-P77170
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Tyrosine-protein phosphatase non-receptor type 9; PTPase MEG2; PTPN9
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Source:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
