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Results for "

PVY

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N13047
    Ningnanmycin

    		TMV SOD Infection
    Ningnanmycin is a plant antiviral agent. Ningnanmycin binds to specific residues on the TMV CP disc, inhibits CP assembly, disassembles the CP disc into monomers, and disrupts the structure of the TMV CP disc to reduce pathogenicity. Ningnanmycin binds to key amino acids of PVY CP, interferes with CP-CP interactions, inhibits CP assembly and virion formation, and blocks PVY replication. Ningnanmycin induces the expression of antiviral response genes PRXIIB, PRXIIE, PUB4 and PER42, thereby activating the host defense system. Ningnanmycin can be used in studies related to Tobacco Mosaic Virus infection and Potato Virus Y infection .
    Ningnanmycin
  • HY-168999
    TSWV-IN-2

    		Tomato Spotted Wilt Virus (TSWV) Infection
    TSWV-IN-2 (Compound Z9) is an inhibitor of TSWV N protein, with an EC50 of 65.3 μg/mL against TSWV. TSWV-IN-2 has broad-spectrum antiviral activity against plant viruses. TSWV-IN-2 targets the TSWV N protein, interferes with the formation of condensates between the N protein and RNA, and inhibits the replication of viral ribonucleoproteins .
    TSWV-IN-2
  • HY-176531
    Antiviral agent 69

    		Others Infection
    Antiviral agent 69 (Compound L2) is a capsid protein residue THR155-targeting inhibitor of phytoviral intercellular traffic. Antiviral agent 69 has an excellent antiviral activity against Potato virus Y (PVY) with an EC50 of 128.10 μg/mL for inactivation effect. Antiviral agent 69 effectively decreases viral accumulation in host plant Nicotiana benthamiana, promising for novel pesticide research and development .
    Antiviral agent 69
  • HY-162403
    Antiviral agent 53

    		Reactive Oxygen Species (ROS) Infection
    Antiviral agent 53 (Compound (S)-4v) is an antiviral agent that can inhibit the activity of Potato virus Y (PVY) and exhibit excellent curative and protective effects against PVY with EC50 values of 328.6 and 256.1 μg/mL, respectively. Antiviral agent 53 can be used in the research and development of novel pesticides .
    Antiviral agent 53
  • HY-179569
    Antiviral agent 73

    		TMV Infection
    Antiviral agent 73 (compound D13) is a potent intercellular movement inhibitor with antiviral activity. Antiviral agent 73 shows inactivation activity against potato virus Y (PVY) with an EC50 of 79.5 μg/mL. Antiviral agent 73 effectively inhibits virus infection by forming stable hydrogen bonds with Pro154 of PVY coat protein. Antiviral agent 73 can interfere with the process of Pro154-mediated viral intercellular trafficking in plasmodesmata. Antiviral agent 73 can be used for plant virus prevention and control .
    Antiviral agent 73

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