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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
Phe-Pro
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "Phe-Pro" in MCE Product Catalog:
7
7 Cited Publications
Cat. No.: HY-P1934
CAS No.: 14705-60-3
Synonyms: Cyclo(PhenylalanylProlyl); A-64863
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2
2 Cited Publications
Cat. No.: HY-122542A
CAS No.: 82188-90-7
Synonyms: Pebac; D-Phenylalanyl-Prolyl-arginyl Chloromethyl Ketone; D-Phe-Pro-Arg-CH2Cl
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PPACK dihydrochloride is a potent, peptidic inhibitor targeting thrombin and granzyme GZMK. PPACK dihydrochloride specifically blocks the activities of thrombin and GZMK, thereby inhibiting thrombin-mediated PAR-1 cleavage, as well as downstream inflammatory and procoagulant signaling pathways. Through stabilizing IκB proteins, blocking NF-κB activation and reducing systemic levels of proinflammatory/procoagulant biomarkers, PPACK dihydrochloride exerts multiple effects including anti-inflammatory, antithrombotic, barrier repair, and inhibition of atherosclerotic plaque progression. PPACK dihydrochloride binds to platelets without interference from kininogen, effectively limiting acute thrombus growth and reducing eosinophil infiltration and goblet cell hyperplasia in asthma models. PPACK dihydrochloride is an important tool molecule for investigating the mechanisms of atherosclerosis, asthma and related thromboinflammatory diseases .
Cat. No.: HY-P4545
CAS No.: 67482-93-3
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Cat. No.: HY-P4470
CAS No.: 201738-99-0
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Cat. No.: HY-P4464
CAS No.: 201732-35-6
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Cat. No.: HY-P4464A
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Cat. No.: HY-P3588
CAS No.: 2920938-90-3
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Cat. No.: HY-P4320
CAS No.: 166184-23-2
Cat. No.: HY-P1937
CAS No.: 53049-06-2
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Cat. No.: HY-P4528
CAS No.: 749831-27-4
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Cat. No.: HY-P4361
CAS No.: 128802-73-3
Cat. No.: HY-D1532
CAS No.: 263718-22-5
Cat. No.: HY-139814
CAS No.: 1979130-73-8
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d-Phe-Pro-Arg-PABA-Resorufin is a selective Thrombin substrate. d-Phe-Pro-Arg-PABA-Resorufin can be cleaved by thrombin to release fluorescent and chromogenic products. d-Phe-Pro-Arg-PABA-Resorufin enables sensitive detection of the thrombin inhibitor Dabigatran (HY-10163) via thrombin-mediated cleavage attenuation .
Synonyms: tert-Butoxycarbonyl-D-Phenylalanyl-L-Proline
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Boc-D-Phe-Pro-OH (tert-Butoxycarbonyl-D-phenylalanyl-L-proline) is a synthetic intermediate useful for pharmaceutical synthesis.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
