d-Phe-Pro-Arg-PABA-Resorufin
d-Phe-Pro-Arg-PABA-Resorufin is a selective Thrombin substrate. d-Phe-Pro-Arg-PABA-Resorufin can be cleaved by thrombin to release fluorescent and chromogenic products. d-Phe-Pro-Arg-PABA-Resorufin enables sensitive detection of the thrombin inhibitor Dabigatran (HY-10163) via thrombin-mediated cleavage attenuation.
For research use only. We do not sell to patients.
- CAS No.: 1979130-73-8
- Formula: C39H42N8O6
- Molecular Weight:718.82
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1979130-73-8
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Molecular Weight 718.82
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Formula C39H42N8O6
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SMILES
O(CC1=CC=C(NC([C@@H](NC(=O)[C@H]2N(C([C@@H](CC3=CC=CC=C3)N)=O)CCC2)CCCNC(=N)N)=O)C=C1)C=4C=C5C(N=C6C(O5)=CC(=O)C=C6)=CC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Arian D, et al. A Chromogenic and Fluorogenic Peptide Substrate for the Highly Sensitive Detection of Proteases in Biological Matrices. J Med Chem. 2016;59(16):7576-7583. [Content Brief]
[2]. Díez-Buitrago B, et al. Biosensing strategies based on enzymatic reactions and nanoparticles. Analyst. 2018;143(8):1727-1734. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)