7 Results for "

Phleomycin

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Phleomycin" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-126490
CAS No.: 11006-33-0
Purity:  ≥95.0%
Phleomycin is a copper-dependent DNA damaging agent and antibiotic with antitumor activity. Phleomycin binds to DNA and produces ROS in the presence of reducing agents (such as dithiothreitol and glutathione), inducing single-strand and double-strand breaks in DNA. Phleomycin can induce cell apoptosis or mutation and is widely used in cancer inhibition, microbial genetic transformation (as a screening marker to improve fungal transformation efficiency) and DNA repair mechanism research .
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2
2 Cited Publications
Cat. No.: HY-111428
CAS No.: 11031-11-1
Synonyms: PLM D1
Target:  

Antibiotic

Research Areas:  

Infection

Phleomycin D1 (PLM D1), a glycopeptide antibiotic, is a member of the Bleomycin/Phleomycin family. Phleomycin D1 causes cell death by binding and cleaving DNA. Phleomycin D1 induces cell cycle arrest at S phase .
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Cat. No.: HY-N10469
CAS No.: 9060-11-1
Synonyms: Phleomycin F
Bleomycin B4 (Phleomycin F) is an antibiotic. Bleomycin B4 has antitumor activity. Bleomycin B4 can be used for the research of cancer .
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Cat. No.: HY-W749297
CAS No.: 9060-10-0
Synonyms: Phleomycin D2
Target:  

DNA Stain

Bleomycin B2 (Phleomycin D2) is an anti-cancer agent that targets DNA. Bleomycin B2 causes DNA strand breaks, thereby inhibiting the growth and proliferation of cancer cells. Bleomycin B2 is promising for research of cancers .
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Cat. No.: HY-N14941
CAS No.: 11031-15-5
Phleomycin G is a heteropeptide antibiotic. Phleomycin G has anti-Gram-positive bacteria, negative bacteria and mycobacterium effects. Phleomycin G extends the survival time of mice transplanted with Ehrman's ascites cancer. Phleomycin G inhibits airy entity carcinoma in mice .
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Cat. No.: HY-N14887
CAS No.: 11031-13-3
Phleomycin E is a heteropeptide antibiotic. Phleomycin E has anti-Gram-positive bacteria, negative bacteria and mycobacterium effects. Phleomycin E extends the survival time of mice transplanted with Ehrman's ascites cancer. Phleomycin E inhibits airy entity carcinoma in mice with an IC50 of 0.31 μg/mL .
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Cat. No.: HY-W749297A
CAS No.: 51773-86-5
Synonyms: Phleomycin D2 sulfate
Research Areas:  

Infection Cancer

Bleomycin B2 (Phleomycin D2) sulfate is a selective antitumor and antibacterial agent that induces DNA strand breaks and inhibits DNA ligase activity. The optimal pH for the activity of Bleomycin B2 sulfate is 9.1, and its efficacy is enhanced by thiol compounds or hydrogen peroxide. Bleomycin B2 sulfate undergoes enzymatic inactivation via bleomycin-inactivating enzymes, exhibits selective retention in squamous cell carcinoma, and is inactivated most rapidly in liver and kidney homogenates. Bleomycin B2 sulfate can be applied in research related to squamous cell carcinoma and other relevant studies .
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