Bleomycin B4  (Synonyms: Phleomycin F)

Bleomycin B4 (Phleomycin F) is an antibiotic. Bleomycin B4 has antitumor activity. Bleomycin B4 can be used for the research of cancer^[1][2][3].

1538.67

C₆₀H₉₅N₂₃O₂₁S₂

9060-11-1

Solid

White to off-white

O[C@H]1[C@@H](OC(N)=O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]2[C@H](O[C@H]([C@H](NC(C3=C(C)C(N)=NC([C@@H](NC[C@H](C(N)=O)N)CC(N)=O)=N3)=O)C(N[C@@H]([C@@H](O)[C@@H](C(N[C@H](C(NCCC4=NC(C5=NC(C(NCCCCN(C(N)=N)CCCCNC(N)=N)=O)=CS5)=CS4)=O)[C@H](O)C)=O)C)C)=O)C6=CNC=N6)O[C@@H](CO)[C@@H](O)[C@@H]2O

Room temperature in continental US; may vary elsewhere.

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

• [1]. T P Korobkova, et al. Optimization of the nutrient medium makeup for the biosynthesis of bleomycine antibiotic using a mathematical method of experimental design. Antibiotiki. 1978 Dec;23(12):1065-8.  [Content Brief]

  [2]. V A Zenkova, et al. Physicochemical and biological properties of bleomycin complex antibiotics. Antibiotiki. 1979 Mar;24(3):175-9.  [Content Brief]

  [3]. A Yagoda, et al. Bleomycin, an antitumor antibiotic. Clinical experience in 274 patients. Ann Intern Med. 1972 Dec;77(6):861-70.  [Content Brief]