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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
Quinazolinone
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "Quinazolinone" in MCE Product Catalog:
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2 Cited Publications
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NKY80 is a potent, selective and non-competitive adenylyl cyclase (AC) type V isoform inhibitor with IC50s of 8.3 µM, 132 µM and 1.7 mM for type V, III and II, respectively. NKY80 is a non-nucleoside quinazolinone and regulates the AC catalytic activity in heart and lung tissues .
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1 Cited Publications
Cat. No.: HY-W018800
CAS No.: 491-36-1
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1 Cited Publications
Cat. No.: HY-N2384
CAS No.: 24159-07-7
Category:
Infection Alkaloids Dichroa febrifuga Lour Pyridine Alkaloids Plants Saxifragaceae Disease Research Fields
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1 Cited Publications
Cat. No.: HY-N2384A
CAS No.: 32434-42-7
Category:
Infection Alkaloids Dichroa febrifuga Lour Pyridine Alkaloids Plants Saxifragaceae Disease Research Fields
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1 Cited Publications
Cat. No.: HY-N5029
CAS No.: 32434-44-9
Category:
Infection Alkaloids Dichroa febrifuga Lour Quinoline Alkaloids Plants Saxifragaceae Disease Research Fields
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Cat. No.: HY-W005308
CAS No.: 69942-12-7
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SL-164 is a quinazolinone. SL-164 has sedative properties .
Cat. No.: HY-W040417
CAS No.: 155905-77-4
Cat. No.: HY-W018800R
CAS No.: 491-36-1
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Nitromethaqualone is a quinazolinone compound that can be used as an analytical reference standard for quinazolinones .
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Methylmethaqualone is a quinazolinone psychoactive substance that can be used as an analytical reference standard for quinazolinone compounds. Methylmethaqualone has acute neurotoxicity and can cause psychomotor stimulation .
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Mebroqualone is structurally categorized as a quinazolinone.
Cat. No.: HY-179251
BDGR-651 is an efficient and selective inhibitor of the Chikungunya virus (CHIKV) with an EC50 in NHDF cells of 0.86 μM, and the therapeutic index (SI) of 22.1. BDGR-651 exhibits dose-dependent protective effects when infecting Vero E6 cells, with its EC50 being 6 μM. BDGR-651 can be used for research on CHIKV infection .
Cat. No.: HY-148906
CAS No.: 853302-91-7
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Anticancer agent 95 (compound 24) is a quinazolinone compound with anticancer effects .
Cat. No.: HY-168261
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CQ-ER is a Coumarin (HY-N0709)-Quinazolinone based endoplasmic reticulum (ER)-targeted photosensitizer. CQ-ER can cause ferroptosis, thereby enhancing photodynamic therapy (PDT) .
Cat. No.: HY-118316
CAS No.: 899758-61-3
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GSK223 is a quinazolinone NOD1 pathway inhibitor with potential anti-inflammatory activity. GSK223 can selectively inhibit IL-8 release under iE-DAP stimulation without affecting IL-8 secretion caused by TNF receptor, TLR2 or NOD2 agonists. GSK223 does not directly inhibit RIP2 kinase activity.
Cat. No.: HY-168260
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CQ-Mito is a Coumarin-Quinazolinone (CQ)-based derivative that targets mitochondria and exhibits profound phototherapeutic performances with an Phototoxic Index (PI) value of 167. CQ-Mito causes cell death by both apoptosis and ferroptosis. CQ-Mito mediates mitochondrial dysfunction, including mitochondrial morphology changed and the loss of MMP. CQ-Mito can efficiently inhibit the tumor growth in organoid tumor models .
Cat. No.: HY-144791
CAS No.: 3027734-50-2
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Bcl-2-IN-6 (compound 10) is a potent Bcl-2 (B-cell lymphoma-2) inhibitor. Bcl-2-IN-7 down-regulates the expression of Bcl-2, and increases the expression of p53, Bax, and caspase-7 mRNA. Bcl-2-IN-7 induces cell cycle arrest and apoptosis in breast cancer MCF-7 cells. Bcl-2-IN-7 shows good anticancer activity, with IC50 values of 20.91, 22.30, 42.29, and 48.00 μM against MCF-7, LoVo, HepG2, and A549 cell lines, respectively .
Cat. No.: HY-144792
CAS No.: 3027734-46-6
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Bcl-2-IN-7 (compound 6) is a potent Bcl-2 (B-cell lymphoma-2) inhibitor. Bcl-2-IN-7 down-regulates the expression of Bcl-2, and increases the expression of p53, Bax, and caspase-7 mRNA. Bcl-2-IN-7 induces cell cycle arrest and apoptosis in breast cancer MCF-7 cells. Bcl-2-IN-7 shows good anticancer activity, with IC50 values of 20.17, 22.64, 45.57, and 51.50 μM against MCF-7, LoVo, HepG2, and A549 cell lines, respectively .
Cat. No.: HY-117171S
CAS No.: 2140327-37-1
Synonyms: 6-Iodo-2-propoxy-d7-3-propyl-4(3H)-Quinazolinone; Proquinazid-d7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
