20 Results for "

RDH

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "RDH" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-W004500
CAS No.: 116-31-4
All-trans-retinal is an vitamin A metabolite in the retina, and is produced following photo-isomerization of the visual chromophore 11-cis-Retinal. All-trans-retinal is cleared from photoreceptors by ATP-binding cassette transporter (ABCA4) and all-trans-retinol dehydrogenase (RDH). All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis .
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Cat. No.: HY-W004500R
CAS No.: 116-31-4
All-trans-retinal (Standard) is the analytical standard of All-trans-retinal. This product is intended for research and analytical applications.
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Cat. No.: HY-175664
Target:  

RPE65

Research Areas:  

Metabolic Disease

EYE-003 is an orally active RPE65 inhibitor with an IC50 of 102 nM. EYE-003 regulates the visual cycle in mice by reducing 11-cis-retinal (11cRAL) (HY-116711) synthesis and increasing all-trans-retinyl esters (atREs). EYE-003 suppresses scotopic ERG b-wave amplitude and exerts protective effects against retinal degeneration in Abca4 ⁻/⁻ Rdh8 ⁻/⁻ mice (a STGD1 model) by reducing retinal autofluorescent puncta and preserving outer nuclear layer (ONL) thickness in a dose-dependent manner. EYE-003 can be used for the study of visual cycle-associated retinopathies, such as Stargardt disease type 1 (STGD1) .
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Cat. No.: HY-RS11798
Research Areas:  

Others

RDH10 Human Pre-designed siRNA Set A contains three designed siRNAs for RDH10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS11800
Research Areas:  

Others

RDH12 Human Pre-designed siRNA Set A contains three designed siRNAs for RDH12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS11801
Research Areas:  

Others

RDH13 Human Pre-designed siRNA Set A contains three designed siRNAs for RDH13 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS11802
Research Areas:  

Others

RDH16 Human Pre-designed siRNA Set A contains three designed siRNAs for RDH16 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS11804
Research Areas:  

Others

RDH8 Human Pre-designed siRNA Set A contains three designed siRNAs for RDH8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS21730
Research Areas:  

Others

Rdh10 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rdh10 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS28247
Research Areas:  

Others

Rdh10 Rat Pre-designed siRNA Set A contains three designed siRNAs for Rdh10 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Cat. No.: HY-RS13573
Research Areas:  

Others

SORD Human Pre-designed siRNA Set A contains three designed siRNAs for SORD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-W587807
CAS No.: 22737-96-8
Target:  

Endogenous Metabolite

Research Areas:  

Neurological Disease

11-cis-Retinol, a form of retinol, can bind to RDH5. 11-cis-Retinol promote dark adaptation and recovery of photoresponsiveness of red cones but not of red rods .
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Cat. No.: HY-RS11799
Research Areas:  

Others

RDH11 Human Pre-designed siRNA Set A contains three designed siRNAs for RDH11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS11803
Research Areas:  

Others

RDH5 Human Pre-designed siRNA Set A contains three designed siRNAs for RDH5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P88886
Synonyms: PAN2; SDR7C4

Host:  

Mouse

Application:  

FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P88886A
Synonyms: PAN2; SDR7C4

Host:  

Mouse

Application:  

FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P88746
Synonyms: ARSDR1; CGI82; HCBP12; MDT1; PSDR1; RALR1; RDJCSS; SCALD; SDR7C1

Host:  

Mouse

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human, Mouse

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Cat. No.: HY-P88746A
Synonyms: ARSDR1; CGI82; HCBP12; MDT1; PSDR1; RALR1; RDJCSS; SCALD; SDR7C1

Host:  

Mouse

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human, Mouse

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Cat. No.: HY-P71328
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SORD; Ribitol Dehydrogenase; Sorbitol Dehydrogenase; RDH; L-Iditol 2-Dehydrogenase; Epididymis Secretory Sperm Binding Protein Li 95n; Xylitol Dehydrogenase; HEL-S-95n; SDH; HMNR8; XDH; SORD1; Polyol Dehydrogenase; SORDD; (R,R)-Butanediol Dehydrogenase
Species:  
Source:  
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Cat. No.: HY-P76871
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DHRS9; Dehydrogenase/Reductase (SDR Family) Member 9; Dehydrogenase/Reductase 9; Dehydrogenase/Reductase SDR Family Member 9; SDR9C4; Short-Chain Dehydrogenase/Reductase RetSDR8; RDH15; Retinol Dehydrogenase Homolog; RDHL; Retinol Dehydrogenase 15; NADP-D
Species:  
Source:  
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