RDH11 Antibody (YA8430)

Cat. No.: HY-P88746: Data Sheet User Guide for Antibodies
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RDH11 Antibody (YA8430) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to RDH11.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

RDH11 Antibody (YA8430) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to RDH11.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 35.2 kDa

Species Reactivity

Human, Mouse

SwissProt ID

Q8TC12

Immunogen

Full length human recombinant protein of human RDH11 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2a

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Retinol dehydrogenase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans-retinol, and to a lesser extent on 13-cis-retinol (PubMed:12036956, PubMed:12226107, PubMed:29410696). Exhibits a low reductive activity towards unsaturated medium-chain aldehydes such as cis -6-nonenal and no activity toward nonanal or 4-hydroxy-nonenal (PubMed:15865448). Has no dehydrogenase activity towards steroid (PubMed:12036956, PubMed:12226107)

Subcellular Localization：Endoplasmic reticulum membrane

Expression：
Tissue_Specificity: Predominantly expressed in the epithelial cells of prostate, in both basal and luminal secretory cell populations. Expressed at low levels in spleen, thymus, testis, ovary, small intestine, colon, peripherical blood leukocytes, kidney, adrenal gland and fetal liver. Not detected in prostatic fibromuscular stromal cells, endothelial cells, or infiltrating lymphocytes
Induction: By androgens in prostate cancer cells

Isoforms & Post-Translational Modification：Q8TC12 has three isomers: Q8TC12-1: 35386 Da (predicted); Q8TC12-2: 34004 Da (predicted); Q8TC12-3: 27402 Da (predicted).
Not glycosylated

Subunit：Interacts with SELENOF

Synonyms

ARSDR1; CGI82; HCBP12; MDT1; PSDR1; RALR1; RDJCSS; SCALD; SDR7C1

Documentation

User Guide for Antibodies (1077 KB)