5 Results for "

RPL15

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "RPL15" in MCE Product Catalog:

79
79 Cited Publications
Cat. No.: HY-13704
CAS No.: 86639-52-3
Purity:  99.94%
Synonyms: 7-Ethyl-10-hydroxycamptothecin
SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 can bind to RPL15. SN-38 inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. SN-38 is a payload of sacituzumab govitecan (HY -132254) .
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Cat. No.: HY-RS12167
Research Areas:  

Others

RPL15 Human Pre-designed siRNA Set A contains three designed siRNAs for RPL15 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P811340
Synonyms: EC45, TCBAP0781, RPL15, Large ribosomal subunit protein eL15, 60S ribosomal protein L15

Host:  

Rabbit

Application:  

WB, IHC-P, FC

Reactivity:  

Human, Mouse

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Cat. No.: HY-180555
Target:  

PROTACs STING

Research Areas:  

Inflammation/Immunology Cancer

SN38-(PEG)2-Pom-α is a selective PROTAC RPL15 degrader. SN38-(PEG)2-Pom-α induces ubiquitin-mediated degradation of RPL15 without affecting TOP1. SN38-(PEG)2-Pom-α induces damage-associated molecular pattern (DAMP) secretion from cancer cells, which activated cGAS-STING signaling in dendritic cells. SN38-(PEG)2-Pom-α enhances anti-PD-1 immunotherapy in a murine melanoma tumor model expressing human CRBN. SN38-(PEG)2-Pom-α can be used for melanoma research .
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Cat. No.: HY-13704S2
CAS No.: 718612-55-6
Synonyms: 7-Ethyl-10-hydroxycamptothecin-13C6
SN-38- 13C6 (7-Ethyl-10-hydroxycamptothecin- 13C6) is the 13C-labeled SN-38 (HY-13704). SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 can bind to RPL15. SN-38 inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. SN-38 is a payload of sacituzumab govitecan (HY -132254) .
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