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Results for "

Radioactive nuclide

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-134797
    p-SCN-Bn-deferoxamine
    1 Publications Verification

    		 Radionuclide-Drug Conjugates (RDCs) Cancer
    P-SCN-Bn-deferoxamine is a bifunctional chelating agent that can link radioactive metal nuclides (such as Zr-89) and biological targeting molecules (such as antibodies). P-SCN-Bn-deferoxamine can be used for the research of immune PET imaging .
    p-SCN-Bn-deferoxamine
  • HY-159771
    FAP6-19

    		FAP Cancer
    FAP6-19 is a fibroblast activation protein (FAP) targeting radioligand with a Kd of 18.2 nM. FAP6-19 selectively delivers therapeutic radioactive nuclides (such as 177Lu) to the tumor site by targeting the overexpressed FAP protein in the tumor microenvironment, achieving precise killing of cancer cells while minimizing radiation damage to healthy tissues. FAP6-19 exhibits extremely high total cellular uptake and good intracellular retention ability in HT1080 cells. After being labeled with 111In, FAP6-19 produced extremely high tumor/kidney and tumor/liver dose ratios in the mouse model with 4T1 tumors. FAP6-19 can be used in the research of solid tumors expressing FAP.
    FAP6-19
  • HY-126565
    Licam-C

    		Biochemical Assay Reagents Others
    Licam-C is a promising radiological decontaminant agent. Acting as a chelating agent, LICAM-C forms stable complexes with radioactive elements such as Plutonium (Pu) and Americium (Am). Licam-C is employed in research addressing the remediation of radioactive nucleotide contamination .
    Licam-C
  • HY-178221
    (S)-P-SCN-BN-NOTA

    		Drug Intermediate Cancer
    (S)-P-SCN-BN-NOTA is a bifunctional chelating agent that can covalently link the radioactive nuclide ⁶⁴Cu with the ZPDGFRβ affibody, thereby constructing a molecular probe [⁶⁴Cu]Cu-NOTA-ZPDGFRβ for positron emission tomography .
    (S)-P-SCN-BN-NOTA
  • HY-164575C
    (S)-NH2-NODAGA hydrochloride

    		Drug Isomer Cancer
    (S)-NH2-NODAGA hydrochloride is the S isomer of NH2-NODAGA hydrochloride (HY-164575B). NH2-NODAGA hydrochloride is a NODAGA-type metal chelator that can bind to radioactive nuclides to prepare nuclide conjugates (RDC). NH2-NODAGA hydrochloride can react with diethyl fumarate in 0.5M phosphoric acid buffer to obtain NODAGA.SA. NODAGA.SA can target L-lysine urea-L-glutamic acid (KuE), and KuE is a key structure of prostate-specific membrane antigen (PSMA). NODAGA.SA.KuE can bind [68]Ga and can be used for PET examination in NMRInu/nu nude mice carrying LNCaP tumors.
    (S)-NH2-NODAGA hydrochloride
  • HY-178248
    PSMA-R2

    		PSMA Cancer
    PSMA ligand 2 is a prostate specific membrane antigen (PSMA) ligand with a glutamate-urea-lysine (GUL) moiety. PSMA ligand 2 can be efficiently labeled with radioactive nuclides such as 68Ga and 177Lu and specifically binds to PSMA-positive tumor cells. PSMA ligand 2 can be used for imaging of PSMA-expressing tumors or cells via PET or SPECT imaging. PSMA ligand 2 can be used for the research of prostate cancer .
    PSMA-R2

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