1222468-90-7
1222468-90-7
Chemical Structure
p-SCN-Bn-deferoxamine
- CAS No.: 1222468-90-7
- Formula:C33H52N8O8S2
- Molecular Weight:752.94
IUPAC Name: N1-hydroxy-N1-(5-(4-(hydroxy(5-(3-(4-isothiocyanatophenyl)thioureido)pentyl)amino)-4-oxobutanamido)pentyl)-N4-(5-(N-hydroxyacetamido)pentyl)succinamide
InChIKey: HBAYEVATSBINBX-UHFFFAOYSA-N
SMILES: O=C(CCC(N(CCCCCNC(CCC(N(CCCCCNC(NC1=CC=C(C=C1)N=C=S)=S)O)=O)=O)O)=O)NCCCCCN(C(C)=O)O
Biological Activity: P-SCN-Bn-deferoxamine is a bifunctional chelating agent that can link radioactive metal nuclides (such as Zr-89) and biological targeting molecules (such as antibodies). P-SCN-Bn-deferoxamine can be used for the research of immune PET imaging[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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p-SCN-Bn-deferoxamine | 98.0% | P-SCN-Bn-deferoxamine is a bifunctional chelating agent that can link radioactive metal nuclides (such as Zr-89) and biological targeting molecules (such as antibodies). P-SCN-Bn-deferoxamine can be used for the research of immune PET imaging. | ||||||||||||||||||||
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References
- [1]. Sobol NB, et al. ImmunoPET Imaging of Pancreatic Tumors with 89Zr-Labeled Gold Nanoparticle-Antibody Conjugates. Mol Imaging Biol. 2021 Feb;23(1):84-94. [Content Brief]
- [2]. Tendler S, et al. Imaging with [89Zr]Zr-DFO-SC16.56 anti-DLL3 antibody in patients with high-grade neuroendocrine tumours of the lung and prostate: a phase 1/2, first-in-human trial. Lancet Oncol. 2024 Aug;25(8):1015-1024. [Content Brief]
