15 Results for "

RhoGEF

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "RhoGEF" in MCE Product Catalog:

Cat. No.: HY-P2269
Target:  

Drug Derivative

Research Areas:  

Cancer

MAIT-203, a cyclopentyalanin-derived peptidomimetic, potently inhibits the interaction of adenomatous polyposis coli (APC) and Asef (RhoGEF4), but not APC-Sam68 or APC-striatin interactions. MAIT-203 binds APC-ARM with a Ki of 0.015 μM and a Kd of 0.036 μM. MAIT-203 significantly represses the migration and invasion of colorectal cancer cells.
Cat. No.: HY-P2269A
Target:  

Drug Derivative

Research Areas:  

Cancer

MAIT-203 acetate is a cyclopentyalanin-derived peptidomimetic, potently inhibits the interaction of adenomatous polyposis coli (APC) and Asef (RhoGEF4), but not APC-Sam68 or APC-striatin interactions. MAIT-203 acetate binds APC-ARM with a Ki value of 0.015 μM and aKd value of 0.036 μM. MAIT-203 acetate significantly represses the migration and invasion of colorectal cancer cells .
Cat. No.: HY-122685
CAS No.: 116679-70-0
Target:  

SOS1

Research Areas:  

Cancer

UC-773587 is a selective SOS1 catalytic activity inhibitor. UC-773587 binds to the catalytic site of Sos1 over HRas and ITSN (a RhoGEF) and inhibits nucleotide exchange with an IC50 value of 4.5 μM. UC-773587 mappes to the Ras switch II interaction region of the Sos1 catalytic site. UC-773587 can be used for the study of prostate cancer .
Cat. No.: HY-P89977
Synonyms: KIAA0380, ARHGEF11, Rho guanine nucleotide exchange factor 11, PDZ-RhoGEF

Host:  

Mouse

Application:  

WB, ICC/IF, IF-Tissue, IP, ELISA

Reactivity:  

human, mouse, rat

Cat. No.: HY-P88171
Synonyms: P114-RhoGEF

Host:  

Mouse

Application:  

IHC-P

Reactivity:  

Human

Cat. No.: HY-P88171A
Synonyms: P114-RhoGEF

Host:  

Mouse

Application:  

IHC-P

Reactivity:  

Human

Cat. No.: HY-P811184
Synonyms: KIAA0380, ARHGEF11, Rho guanine nucleotide exchange factor 11, PDZ-RhoGEF

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse

Cat. No.: HY-P811186
Synonyms: KIAA0380; Rho guanine nucleotide exchange factor 11; PDZ-RhoGEF

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

Cat. No.: HY-P811160
Synonyms: KIAA0382, LARG, ARHGEF12, Rho guanine nucleotide exchange factor 12, Leukemia-associated RhoGEF

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

Cat. No.: HY-P89553
Synonyms: KIAA1556, KIAA1639, OBSCN, Obscurin, Obscurin-RhoGEF, Obscurin-myosin light chain kinase, Obscurin-MLCK

Host:  

Mouse

Application:  

WB, IP, ELISA

Reactivity:  

human

Cat. No.: HY-P810045
Synonyms: Zinc finger FYVE domain-containing protein 5, ZFYVE5, FYVE, RhoGEF and PH domain-containing protein 3

Host:  

Mouse

Application:  

WB, ICC/IF, IF-Tissue, IHC-P, IP, ELISA

Reactivity:  

human

Cat. No.: HY-P89856
Synonyms: Lbcl2, Lsc, Arhgef1, Rho guanine nucleotide exchange factor 1, Lbc's second cousin, Lymphoid blast crisis-like 2

Host:  

Mouse

Application:  

WB, IP, ELISA

Reactivity:  

human

Cat. No.: HY-P810959
Synonyms: KIAA0651, LFP40, ARHGEF2, Rho guanine nucleotide exchange factor 2, Guanine nucleotide exchange factor H1, Microtubule-regulated Rho-GEF, Proliferating cell nucleolar antigen p40, GEF-H1

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

Cat. No.: HY-P811178
Synonyms: KIAA0651; LFP40; Rho guanine nucleotide exchange factor 2; Guanine nucleotide exchange factor H1; GEF-H1; Microtubule-regulated Rho-GEF; Proliferating cell nucleolar antigen p40

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse

Cat. No.: HY-P811176
Synonyms: KIAA0651, LFP40, ARHGEF2, Rho guanine nucleotide exchange factor 2, Guanine nucleotide exchange factor H1, Microtubule-regulated Rho-GEF, Proliferating cell nucleolar antigen p40, GEF-H1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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