NPR2 Antibody
(Synonyms: KIAA0380; Rho guanine nucleotide exchange factor 11; PDZ-RhoGEF)NPR2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to NPR2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:50-200 |
Product Details
NPR2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to NPR2.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
Synthetic peptide corresponding to the center region of human NPR2.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
NPR2 is a Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth
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Subcellular Localization
Cell membrane
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Isoforms & Post-Translational Modification
NPR2 has 2 isoforms, P20594-1: amino acid length is 1047, molecular weight is 117022 Da (predicted); P20594-2: amino acid length is 995, molecular weight is 111208 Da (predicted).发生磷酸化修饰(PubMed:26980729)。类蛋白激酶结构域的磷酸化是 CNP 使其完全激活所必需的(根据相似性推断)NPR2 存在 2 个异构体，P20594-1：氨基酸个数为 1047 个，分子量为 117022 Da (预测)；P20594-2：氨基酸个数为 995 个，分子量为 111208 Da (预测)。Phosphorylated (PubMed:26980729). Phosphorylation of the protein kinase-like domain is required for full activation by CNP (By similarity)
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SwissProt ID
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Synonyms
KIAA0380; Rho guanine nucleotide exchange factor 11; PDZ-RhoGEF
Documentation
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