1 Result for "

SAR442085

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SAR442085" in MCE Product Catalog:

Cat. No.: HY-P992455

Research Areas:  

Cancer

SAR442085 is an Fc-engineered anti-CD38 monoclonal antibody with a Kd of 0.2 nM for human CD38. SAR442085 inhibits CD38, induces apoptosis, and triggers antibody-dependent cellular cytotoxicity and phagocytosis in CD38-expressing tumor cells. SAR442085 binds allelic variants of FcγRIIa and FcγRIIIa, enhances NK cell activation, degranulation and cytokine secretion, and exerts anti-tumor activity in human Fc receptor transgenic mice. SAR442085 can be used in the research of multiple myeloma .
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