1 Result for "

STAT3-IN-18

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "STAT3-IN-18" in MCE Product Catalog:

Cat. No.: HY-155808
CAS No.: 2668267-41-0
Target:  

STAT JAK Apoptosis COX

Research Areas:  

Cancer

STAT3-IN-18 (compound SPP) is a platinum (IV) complex with an axial ligand derived from sandalwood. STAT3-IN-18 inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, with anti-proliferative activity. STAT3-IN-18 activates caspase-3 and increases cleaved polyADP-ribose polymerase to induce apoptosis. STAT3-IN-18 promotes maturation and antigen presentation of dendritic cells and demonstrates safety in vivo.
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