Search Result
Results for "
SUB1
" in MedChemExpress (MCE) Product Catalog:
6
Biochemical Assay Reagents
385
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-15176B
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RR82 TFA
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DNA/RNA Synthesis
G-quadruplex
Flavivirus
Src
Virus Protease
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Cancer
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Pyridostatin (RR82) TFA is a G-quadruplex (G4) inducer/stabilizer with a Kd of 490 nM. Pyridostatin TFA also acts as an inhibitor of Zika virus (ZIKV) NS2B-NS3 protease, with an IC50 of 11.0 μM. Pyridostatin TFA interacts with G-quadruplex structures, regulates the expression of SRC and SUB1, and induces replication- and transcription-dependent DNA damage, growth arrest, and genomic instability. Pyridostatin TFA exhibits antiproliferative and antiviral activities. Pyridostatin TFA can be used in studies related to breast cancer, cervical cancer, and Zika virus infection [1] .
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- HY-15176C
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RR82 trihydrochloride
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DNA/RNA Synthesis
G-quadruplex
Flavivirus
Src
Virus Protease
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Cancer
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Pyridostatin (RR82) trihydrochloride is a G-quadruplex (G4) inducer/stabilizer with a Kd of 490 nM. Pyridostatin trihydrochloride also acts as an inhibitor of Zika virus (ZIKV) NS2B-NS3 protease, with an IC50 of 11.0 μM. Pyridostatin trihydrochloride interacts with G-quadruplex structures, regulates the expression of SRC and SUB1, and induces replication- and transcription-dependent DNA damage, growth arrest, and genomic instability. Pyridostatin trihydrochloride exhibits antiproliferative and antiviral activities. Pyridostatin trihydrochloride can be used in studies related to breast cancer, cervical cancer, and Zika virus infection [1] .
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- HY-B0892S4
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- HY-13966S
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2-DG-d<SUB>1SUB>; 2-Deoxy-D-arabino-hexose-d<SUB>1SUB>; D-Arabino-2-deoxyhexose-d<SUB>1SUB>
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Isotope-Labeled Compounds
Apoptosis
Hexokinase
HSV
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Cancer
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2-Deoxy-D-glucose-d is the deuterium labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase [1] .
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- HY-B0389S1
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Glucose-d<SUB>1SUB>; D-(+)-Glucose-d<SUB>1SUB>; Dextrose-d<SUB>1SUB>
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Isotope-Labeled Compounds
Endogenous Metabolite
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Metabolic Disease
Cancer
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D-Glucose-d is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molec
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- HY-B0152S
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6-Aminopurine-d<SUB>1SUB>; Vitamin B4-d<SUB>1SUB>
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DNA/RNA Synthesis
Endogenous Metabolite
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Cancer
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Adenine-d is the deuterium labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis [1] .
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- HY-N7092S11
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- HY-RS13999
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Small Interfering RNA (siRNA)
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Others
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SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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SUB1 Human Pre-designed siRNA Set A
SUB1 Human Pre-designed siRNA Set A
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- HY-B0389S2
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Glucose-d<SUB>12SUB>-1; D-(+)-Glucose-d<SUB>12SUB>-1; Dextrose-d<SUB>12SUB>-1
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Isotope-Labeled Compounds
Endogenous Metabolite
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Metabolic Disease
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D-Glucose-d12-12 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response [1].
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- HY-B0389S8
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Glucose-d<SUB>1SUB>-4; D-(+)-Glucose-d<SUB>1SUB>-4; Dextrose-d<SUB>1SUB>-4
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Isotope-Labeled Compounds
Endogenous Metabolite
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Metabolic Disease
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D-Glucose-d-44 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response [1].
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- HY-B0511S
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- HY-14648S5
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Hexadecadrol-d<SUB>3SUB>-1; Prednisolone F-d<SUB>3SUB>-1
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Isotope-Labeled Compounds
Antibiotic
Autophagy
Glucocorticoid Receptor
SARS-CoV
ADC Payload
Mitophagy
Complement System
Bacterial
Exosomes
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Cancer
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Dexamethasone-d3-1 (Hexadecadrol-d3-1; Prednisolone F-d3-1) is a deuterium labeled Dexamethasone (HY-14648). Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.
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- HY-10585S4
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VPA-d<SUB>4SUB>-1; 2-Propylpentanoic acid-d<SUB>4SUB>-1
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Isotope-Labeled Compounds
HDAC
Autophagy
Mitophagy
HIV
Notch
Endogenous Metabolite
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Cancer
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Valproic acid-d4-1 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches [1] .
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- HY-12215S2
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PF-06463922-d<SUB>3SUB>-1
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Isotope-Labeled Compounds
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Cancer
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Deulorlatinib (compound A), a deuterated derivative of Lorlatinib (HY-12215), is a potent inhibitor of tyrosine kinase demonstrating the potential for the research of ALK-positive advanced NSCLC [1] .
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- HY-W004263S
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Arachidyl alcohol-d<SUB>41SUB>
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Isotope-Labeled Compounds
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Metabolic Disease
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1-Eicosanol-d41 (Arachidyl alcohol-d41) is the deuterium labeled 1-Eicosanol (HY-W004263) [1]. 1-Eicosanol is a natural compound with antioxidant activity found in Justicia insularis leaves. 1-Eicosanol can be used as an antioxidant .
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- HY-RS18793
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Small Interfering RNA (siRNA)
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Others
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Sub1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Sub1 Mouse Pre-designed siRNA Set A
Sub1 Mouse Pre-designed siRNA Set A
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- HY-RS25282
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Small Interfering RNA (siRNA)
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Others
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Sub1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Sub1 Rat Pre-designed siRNA Set A
Sub1 Rat Pre-designed siRNA Set A
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- HY-P10215
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Parasite
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Infection
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Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent Plasmodium subtilisin-like protease 1 (SUB1) inhibitor. SUB1-IN-1 shows IC50 values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively [1].
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- HY-W016577S4
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- HY-B0389S4
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Glucose-d<SUB>1SUB>-2; D-(+)-Glucose-d<SUB>1SUB>-2; Dextrose-d<SUB>1SUB>-2
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Isotope-Labeled Compounds
Endogenous Metabolite
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Metabolic Disease
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D-Glucose-d1-2 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response [1].
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- HY-B1411S1
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- HY-10162S3
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AZD2281-d<SUB>4SUB>-1; KU0059436-d<SUB>4SUB>-1
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Isotope-Labeled Compounds
PARP
Autophagy
Mitophagy
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Cancer
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Olaparib-d4-1 (AZD2281-d4-1) is the deuterium labeled Olaparib (HY-10162). Olaparib is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator [1] .
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- HY-70057S1
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FCE 26743-d<SUB>4SUB>-1; EMD 1195686-d<SUB>4SUB>-1
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Isotope-Labeled Compounds
Monoamine Oxidase
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Neurological Disease
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Safinamide-d4-1 is deuterium labeled Safinamide. Safinamide is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 μM) over MAO-A (IC50=580 μM) [1]. Safinamide also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC50=8?μM) than at resting (IC50=262?μM) potentials. Safinamide has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke etc.al .
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- HY-100442S1
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ABR-215757-d<SUB>5SUB>-1; ABR 25757-d<SUB>5SUB>-1
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SARS-CoV
Isotope-Labeled Compounds
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Metabolic Disease
Inflammation/Immunology
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Paquinimod-d5-1 is a deuterated analog of Paquinimod (HY-100442). Paquinimod (ABR 215757) is a specific and orally active inhibitor of S100A8/S100A9. Paquinimod rescues the pneumonia with substantial reduction of viral loads in SARS-CoV-2-infected mice [1] .
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- HY-B1659S3
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- HY-W032013S1
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Octanol-d<SUB>2SUB>
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Calcium Channel
Endogenous Metabolite
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Metabolic Disease
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1-Octanol-d2 is the deuterium labeled 1-Octanol [1]. 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents . 1-Octanol is a highly attractive biofuel with diesel-like properties .
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- HY-A0070AS2
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Triiodothyronine-13C<SUB>6SUB>-1; 3,3',5-Triiodo-L-thyronine-13C<SUB>6SUB>-1; T3-13C<SUB>6SUB>-1
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Thyroid Hormone Receptor
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Endocrinology
Cancer
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Liothyronine- 13C6-1 is a 13C-labeled Liothyronine. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively [1] .
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- HY-W004292S
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Undecyl alcohol-d<SUB>23SUB>
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Isotope-Labeled Compounds
Drug Derivative
Insecticide
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Infection
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1-Undecanol-d23 (Undecyl alcohol-d23) is the deuterium labeled 1-Undecanol (HY-W004292). 1-Undecanol (Undecyl alcohol) is the main product generated from the degradation of 2-tridecanone by Pseudomonas bacteria isolated from the soil. 1-Undecanol can enhance the attraction of Grapholita molesta to sex pheromone traps [1] .
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- HY-N0210S6
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- HY-109037S2
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MYK461-d<SUB>1SUB>; SAR439152-d<SUB>1SUB>
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Isotope-Labeled Compounds
Myosin
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Cardiovascular Disease
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Mavacamten-d1 (MYK461-d1; SAR439152-d1) is deuterium labeled Mavacamten (HY-109037). Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively.
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- HY-N0488S1
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Leurocristine-d<SUB>3SUB>-1 sulfate; NSC-67574-d<SUB>3SUB>-1 sulfate; 22-Oxovincaleukoblastine-d<SUB>3SUB>-1 sulfate
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Isotope-Labeled Compounds
Apoptosis
Mitosis
Microtubule/Tubulin
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Cancer
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Vincristine-d3 sulfate is the deuterium labeled Vincristine sulfate. Vincristine-1 sulfate (Leurocristine; NSC-67574; 22-Oxovincaleukoblastine) is a microtubule inhibitor that disrupts microtubule polymerization by binding to β-tubulin (with a Ki of 85 nM in bovine), arrests the cell cycle and induces apoptosis. Vincristine-1 sulfate inhibits cell replication, tumor blood flow and the proliferation of various cancer cells, while triggering effects such as oxidative stress, inflammation, calcium overload, epithelial-mesenchymal transition and peripheral neuropathic pain. Vincristine-1 sulfate upregulates the expression of various transporters and nuclear receptors, and enriches gastric cancer stem-like cells. Vincristine-1 sulfate is used in research related to various tumors including acute lymphoblastic leukemia, lymphoma, melanoma, gastric cancer, solid tumors and sarcomas [1] .
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- HY-14648S1
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- HY-108506S2
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BIA 2-005-d<SUB>4SUB>-1; GP 47779-d<SUB>4SUB>-1
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Isotope-Labeled Compounds
Sodium Channel
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Neurological Disease
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Licarbazepine-d4-1 is deuterium labeled Licarbazepine. Licarbazepine (BIA 2-005; GP 47779)?is a?voltage-gated sodium channel?blocker?with?anticonvulsant?and?mood-stabilizing?effects [1].
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- HY-W778692
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1-Linoleoyl-rac-glycerol-d<SUB>5SUB>; 1-Monolinolein-d<SUB>5SUB>
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Isotope-Labeled Compounds
Interleukin Related
Phospholipase
Apolipoprotein
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Metabolic Disease
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1-Linoleoyl Glycerol-d5 (1-Linoleoyl-rac-glycerol-d5; 1-Monolinolein-d5) is the deuterium labeled 1-Linoleoyl Glycerol (HY-111346). 1-Linoleoyl glycerol is a LpPLA2 inhibitor. 1-Linoleoyl glycerol acts as a precursor for synthesizing various functional lipids, such as phospholipids. 1-Linoleoyl glycerol mitigates inflammation induced by Apolipoprotein CIII (reduction of IL-6) [1] .
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- HY-13331S2
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Cortexolone 17 alpha-propionate-d<SUB>5SUB>-1; Cortexolone 17α-propionate-d<SUB>5SUB>-1; CB-03-01-d<SUB>5SUB>-1
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Isotope-Labeled Compounds
Androgen Receptor
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Endocrinology
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Clascoterone-d5-1 (Cortexolone 17 alpha-propionate-d5-1) is deuterium labeled Clascoterone. Clascoterone (Cortexolone 17 alpha-propionate;Cortexolone 17α-propionate;CB-03-01) is a new topical and peripherally selective androgen antagonist [1].
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- HY-Y0308S
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Exsiccated sodium phosphate-d<SUB>1SUB>
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Isotope-Labeled Compounds
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Others
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Phosphate dibasic-d2 (sodium) is the deuterium labeled Sodium phosphate dibasic [1].
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- HY-18341S4
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Levothyroxine-13C<SUB>6SUB>-1; T4-13C<SUB>6SUB>-1
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Isotope-Labeled Compounds
Endogenous Metabolite
Thyroid Hormone Receptor
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Endocrinology
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L-Thyroxine- 13C6-1 (Levothyroxine- 13C6-1; T4- 13C6-1) is a 13C labeled L-Thyroxine (HY-18341). L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) [1] .
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- HY-W004293S
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- HY-41700S2
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- HY-N0378S5
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Mannitol-d<SUB>1SUB>; Mannite-d<SUB>1SUB>
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Isotope-Labeled Compounds
Endogenous Metabolite
Apoptosis
PGC-1α
Adrenergic Receptor
PKA
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Cardiovascular Disease
Metabolic Disease
Cancer
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D-Mannitol-d is the deuterium labeled D-Mannitol (HY-N0378). D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells [1] . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .
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- HY-B0389S7
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Glucose-d<SUB>1SUB>-3; D-(+)-Glucose-d<SUB>1SUB>-3; Dextrose-d<SUB>1SUB>-3
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Endogenous Metabolite
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Metabolic Disease
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D-Glucose-d-33 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response [1].
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- HY-19696S2
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Tauroursodeoxycholic acid-d<SUB>4SUB>-1; TUDCA-d<SUB>4SUB>-1; UR 906-d<SUB>4SUB>-1
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Isotope-Labeled Compounds
ERK
Caspase
Endogenous Metabolite
Apoptosis
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Cancer
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Tauroursodeoxycholate-d4-1 is the deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.
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- HY-B0141S6
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- HY-B0763S2
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KC-404-d<SUB>7SUB>-1; AV-411-d<SUB>7SUB>-1; MN-166-d<SUB>7SUB>-1
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Phosphodiesterase (PDE)
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Inflammation/Immunology
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Ibudilast-d7-1 is the deuterium labeled Ibudilast [1]. Ibudilast (KC-404;AV-411;MN-166) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia .
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- HY-B0228S7
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- HY-B0479S1
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Thiophenicol-d<SUB>3SUB>-1; Dextrosulphenidol-d<SUB>3SUB>-1
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Isotope-Labeled Compounds
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Infection
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Thiamphenicol-d3-1 (Thiophenicol-d3-1; Dextrosulphenidol-d3-1) is the deuterium-labeled Thiamphenicol (HY-B0479) [1]. Thiamphenicol (Thiophenicol)，a methyl-sulfonyl derivative of Chloramphenicol，is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit，leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative，Gram-positive aerobic and anaerobic bacteria) .
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- HY-12222S1
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INT-747-d<SUB>4SUB>-1; 6-ECDCA-d<SUB>4SUB>-1; 6-Ethylchenodeoxycholic acid-d<SUB>4SUB>-1
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FXR
Autophagy
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Others
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Obeticholic Acid-d4 is the deuterium labeled Obeticholic acid. Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy [1] .
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- HY-14649S6
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Vitamin A acid-d<SUB>3SUB>-1; all-trans-Retinoic acid-d<SUB>3SUB>-1; ATRA-d<SUB>3SUB>-1
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Isotope-Labeled Compounds
RAR/RXR
PPAR
Endogenous Metabolite
Autophagy
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Metabolic Disease
Cancer
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Retinoic acid-d3-1 is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha [1] .
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- HY-B0234S4
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E1-d<SUB>2SUB>-1; Oestrone-d<SUB>2SUB>-1
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Isotope-Labeled Compounds
Estrogen Receptor/ERR
Endogenous Metabolite
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Endocrinology
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Estrone-d2-1 is the deuterium labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells [1] .
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- HY-17043S2
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- HY-23188
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Loratidine-d<SUB>5SUB>-1; SCH 29851-d<SUB>5SUB>-1
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Isotope-Labeled Compounds
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Others
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Loratadine-d5-1 is a deuterated labeled Loratadine (HY-17043). Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory mediators.
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- HY-50898S3
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GW572016-d<SUB>4SUB>-1; GW2016-d<SUB>4SUB>-1
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Isotope-Labeled Compounds
EGFR
Autophagy
Ferroptosis
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Cancer
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Lapatinib-d4-1 is deuterium labeled Lapatinib. Lapatinib (GW572016) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively [1].
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- HY-B0400S7
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Sorbitol-d<SUB>1SUB>-2; D-Glucitol-d<SUB>1SUB>-2
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Endogenous Metabolite
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Others
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D-Sorbitol-d-2 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and di
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- HY-G0016S1
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- HY-B0400S8
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Sorbitol-d<SUB>2SUB>-1; D-Glucitol-d<SUB>2SUB>-1
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Endogenous Metabolite
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Others
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D-Sorbitol-d2-1 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and di
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- HY-13593S1
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CB-1348-d<SUB>8SUB>-1; WR-139013-d<SUB>8SUB>-1
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Isotope-Labeled Compounds
DNA Alkylator/Crosslinker
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Cancer
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Chlorambucil-d8-1 is the deuterium labeled Chlorambucil. Chlorambucil (CB-1348), an orally active antineoplastic agent, is a bifunctional alkylating agent belonging to the nitrogen mustard group. Chlorambucil can be used for the research of lymphocytic leukemia, ovarian and breast carcinomas, and Hodgkin’s disease [1] .
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- HY-B0801S4
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MDL-16455-d<SUB>3SUB>-1; Terfenadine carboxylate-d<SUB>3SUB>-1
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Histamine Receptor
Isotope-Labeled Compounds
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Inflammation/Immunology
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Fexofenadine-d3-1 fumarate is deuterated labeled Fexofenadine (HY-B0801). Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research [1] .
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-
- HY-A0095S1
-
|
BIMT-17-d<SUB>4SUB>-1; BIMT-17BS-d<SUB>4SUB>-1
|
Isotope-Labeled Compounds
5-HT Receptor
|
Neurological Disease
|
|
Flibanserin-d4-1 is deuterium labeled Flibanserin. Flibanserin (BIMT-17) is a full agonist of the serotonin 5-HT1A receptor (Ki=1 nM) and an antagonist of 5-HT2A (49 nM). Flibanserin binds to dopamine D4 receptors (4-24 nM), and has negligible affinity for a variety of other neurotransmitter receptors and ion channels. Flibanserin is efficacious in treating hypoactive sexual desire disorder (HSDD) [1] .
|
-
- HY-15592S2
-
|
GSK-1265744-d<SUB>3SUB>-1; S/GSK1265744-d<SUB>3SUB>-1
|
Isotope-Labeled Compounds
HIV Integrase
|
Infection
|
|
Cabotegravir d3-1 (GSK-1265744-d3-1) is a deuterium substitute of Cabotegravir. Cabotegravir is a potent HIV integrase inhibitor used in AIDS research [1]
|
-
- HY-B1716S1
-
|
L-5-HTP-d<SUB>3SUB>-1; Oxitriptan-d<SUB>3SUB>-1
|
Endogenous Metabolite
|
Metabolic Disease
|
|
L-5-Hydroxytryptophan-d3-1 is the deuterium labeled L-5-Hydroxytryptophan [1]. L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist . L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia .
|
-
- HY-B0389S18
-
|
Glucose-13C<SUB>3SUB>-1; D-(+)-Glucose-13C<SUB>3SUB>-1; Dextrose-13C<SUB>3SUB>-1
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
D-Glucose- 13C3-1 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response [1].
|
-
- HY-B0389S25
-
|
Glucose-13C,d<SUB>1SUB>; D-(+)-Glucose-13C,d<SUB>1SUB>; Dextrose-13C,d<SUB>1SUB>
|
Endogenous Metabolite
|
Metabolic Disease
Cancer
|
|
D-Glucose- 13C,d is the deuterium and 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical sig
|
-
- HY-B0158S4
-
-
- HY-141636S
-
|
1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine-d<SUB>9SUB>-1; PAPC-d<SUB>9SUB>-1; PC(16:0/20:4)-d<SUB>9SUB>-1
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cardiovascular Disease
|
|
1-PalMitoyl-2-arachidoyllecithin-d9-1 (1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine-d9-1) is deuterium labeled 1-PalMitoyl-2-arachidoyllecithin. 1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PC (PAPC) is a phospholipid containing palmitic acid (16:0) and arachidonic acid (20:4) at the sn-1 and sn-2 positions, respectively, that is found in biological membranes. PAPC is oxidized in vivo, and its oxidation products are involved in chronic inflammation and vascular disease. PAPC has been used to study signaling of oxidized phospholipids. Levels of PAPC are decreased in isolated human multiple myeloma cells [1].
|
-
- HY-W032013S
-
|
Octanol-d<SUB>17SUB>
|
Calcium Channel
Endogenous Metabolite
|
Metabolic Disease
|
|
1-Octanol-d17 is the deuterium labeled 1-Octanol [1]. 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents . 1-Octanol is a highly attractive biofuel with diesel-like properties .
|
-
- HY-W032013S3
-
|
Octanol-d<SUB>5SUB>
|
Calcium Channel
Endogenous Metabolite
Isotope-Labeled Compounds
|
Others
|
|
1-Octanol-d5 is deuterated labeled 1-Octanol (HY-W032013). 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents [1]. 1-Octanol is a highly attractive biofuel with diesel-like properties .
|
-
- HY-B0158S3
-
-
- HY-W720915
-
|
1-Dodecylbenzene-d<SUB>5SUB>; 1-Phenyl-n-dodecane-d<SUB>5SUB>; 1-Phenyldodecane-d<SUB>5SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
N-Dodecylbenzene-d5 (1-Dodecylbenzene-d5; 1-Phenyl-n-dodecane-d5; 1-Phenyldodecane-d5) is the deuterium labeled N-Dodecylbenzene (HY-Y1052).
|
-
- HY-66008S1
-
|
N-Acetyl-5-aminosalicylic acid-d<SUB>3SUB>-1; N-Acetyl-ASA-d<SUB>3SUB>-1
|
Isotope-Labeled Compounds
Drug Metabolite
|
Inflammation/Immunology
Cancer
|
|
N-Acetyl mesalazine-d3-1 (N-Acetyl-5-aminosalicylic acid-d3-1) is deuterium labeled N-Acetyl mesalazine (HY-66008). N-Acetyl mesalazine (N-Acetyl-5-aminosalicylic acid) is the primary intestinal metabolite of 5-Aminosalicylic Acid (HY-15027) and serves as a biomarker for evaluating the efficacy of 5-Aminosalicylic Acid (HY-15027). N-Acetyl mesalazine can scavenge free radicals, reduce DNA base hydroxylation, and ameliorate mucosal inflammation. N-Acetyl mesalazine can be used in the study of diseases such as colitis and colon cancer [1].
|
-
- HY-A0042S2
-
|
CGP 33101-15N,d<SUB>2SUB>-1; E 2080-15N,d<SUB>2SUB>-1; RUF 331-15N,d<SUB>2SUB>-1
|
Isotope-Labeled Compounds
Sodium Channel
|
Neurological Disease
|
|
Rufinamide- 15N,d2-1 (CGP 33101- 15N,d2-1) is 15N- and deuterium-labeled Rufinamide (HY-A0042).Rufinamide (CGP 33101) is an orally active antiepileptic compound that inhibits Na + current activation, inhibits neuronal hyperexcitability, and has anticonvulsant effects. Rufinamide is used in the study of Lennox-Gastaut syndrome [1] .
|
-
- HY-B0122SS1
-
-
- HY-N0717S8
-
|
(S)-Valine-d<SUB>1SUB>
|
Isotope-Labeled Compounds
Arginase
Akt
Bacterial
|
Infection
|
|
L-Valine-d1 ((S)-Valine-d1) is the deuterium labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase [1] .
|
-
- HY-N0131S1
-
-
- HY-W004292S1
-
|
Undecyl alcohol-d<SUB>4SUB>
|
Isotope-Labeled Compounds
Drug Derivative
Insecticide
|
Infection
|
|
1-Undecanol-d4 (Undecyl alcohol-d4) is the deuterium labeled 1-Undecanol (HY-W004292). 1-Undecanol (Undecyl alcohol) is the main product generated from the degradation of 2-tridecanone by Pseudomonas bacteria isolated from the soil. 1-Undecanol can enhance the attraction of Grapholita molesta to sex pheromone traps [1] .
|
-
- HY-152070S1
-
-
- HY-135810S1
-
|
Desethylhydroxychloroquine-d<SUB>4SUB>-1
|
Isotope-Labeled Compounds
CHIKV
Influenza Virus
Parasite
|
Infection
Inflammation/Immunology
|
|
Cletoquine-d4-1 is the deuterium labeled Cletoquine. Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune diseases treatment [1] .
|
-
- HY-B0412S4
-
-
- HY-B0111S1
-
-
- HY-Y1004S3
-
-
- HY-B0389S3
-
|
Glucose-d<SUB>1SUB>-1; D-(+)-Glucose-d<SUB>1SUB>-1; Dextrose-d<SUB>1SUB>-1
|
Endogenous Metabolite
|
Metabolic Disease
|
|
D-Glucose-d-11 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response [1].
|
-
- HY-W099504S2
-
-
- HY-B0389S23
-
|
Glucose-d<SUB>2SUB>-1; D-(+)-Glucose-d<SUB>2SUB>-1; Dextrose-d<SUB>2SUB>-1
|
Endogenous Metabolite
|
Metabolic Disease
Cancer
|
|
D-Glucose-d2-1 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling mol
|
-
- HY-109025AS2
-
|
Baloxavir acid-d<SUB>1SUB>; S-033447-d<SUB>1SUB>
|
Isotope-Labeled Compounds
Influenza Virus
|
Infection
Cancer
|
|
Baloxavir-d1 is the deuterium labeled Baloxavir (HY-109025A). Baloxavir (Baloxavir acid), derived from the proagent Baloxavir marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir inhibits viral RNA transcription and replication and has potently antiviral activity [1] .
|
-
- HY-Y0001S1
-
|
Carboxycyclopropane-d<SUB>1SUB>; Cyclopropionic acid-d<SUB>1SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
Cyclopropane-1-carboxylic Acid-d1 is the deuterium labeled Cyclopropane-1-carboxylic Acid [1].
|
-
- HY-W051547S2
-
|
2-Chloro-3-(1-hydroxyethyl)pyridine-d<SUB>1SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-(2-Chloropyridin-3-yl)ethanol-d1 (2-Chloro-3-(1-hydroxyethyl)pyridine-d1) is the deuterium labeled 1-(2-Chloropyridin-3-yl)ethanol.
|
-
- HY-W752893
-
|
D-(-)-4-Hydroxyphenylglycine-d<SUB>5SUB>-1; 4-Hydroxy-D-phenylglycine-d<SUB>5SUB>-1
|
Isotope-Labeled Compounds
Antibiotic
|
Others
|
|
D-4-Hydroxyphenylglycine-d5-1 (D-(-)-4-Hydroxyphenylglycine-d5-1) is the deuterium labeled D-4-Hydroxyphenylglycine (HY-34588). D-4-Hydroxyphenylglycine (D-(-)-4-Hydroxyphenylglycine) is one of the most important raw materials used in the production of semisynthetic β-lactam antibiotics, such as Amoxicillin (HY-B0467A) and Cefadroxil (HY-B1190) [1].
|
-
- HY-W087024S
-
-
- HY-145547S
-
|
14:0 Lyso PE-d<SUB>27SUB>; 1-Myristoyl-2-hydroxy-sn-glycero-3-PE-d<SUB>27SUB>; 1-Tetradecanoyl-sn-glycero-3-phosphoethanolamine-d<SUB>27SUB>
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine-d27 (14:0 Lyso PE-d27) is the deuterium labeled 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine. 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells [1].
|
-
- HY-178736S
-
|
DLPE-d<SUB>46SUB>; 1,2-Dilauroyl-sn-glycero-3-PE-d<SUB>46SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine-d46 (DLPE-d46) is the deuterium labeled 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine.
|
-
- HY-34705S
-
-
- HY-Y1004S4
-
-
- HY-W014559S4
-
-
- HY-Y1809S
-
|
Stearyl alcohol-d<SUB>37SUB>
|
Endogenous Metabolite
|
Metabolic Disease
|
|
1-Hydroxyoctadecane-d37 is the deuterium labeled 1-Hydroxyoctadecane [1]. 1-Hydroxyoctadecane is an endogenous metabolite.
|
-
- HY-122426S1
-
-
- HY-124891S
-
|
N-Phenylpyrrole-d<SUB>9SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Phenylpyrrole-d9 (N-Phenylpyrrole-d9) is the deuterium labeled 1-Phenylpyrrole (HY-124891). 1-Phenylpyrrole (N-Phenylpyrrole) has dual fluorescent properties. 1-Phenylpyrrole displays a single band in nonpolar solvents and a second red-shifted fluorescent band in polar solvents [1].
|
-
- HY-W723937
-
-
- HY-W009141S
-
|
Glyceryl palmitate-d<SUB>31SUB>
|
Isotope-Labeled Compounds
P-glycoprotein
PI3K
Apoptosis
Caspase
IAP
Akt
|
Cancer
|
|
1-Monopalmitin-d31 (Glyceryl palmitate-d31) is the deuterium labeled 1-Monopalmitin (HY-W009141). 1-Monopalmitin (Glyceryl palmitate) is an activator of the PI3K/Akt pathway and an inhibitor of P-glycoprotein (P-gp). 1-Monopalmitin can induce G2/M arrest and caspase-dependent apoptosis in cancer cells, while inhibiting IAPs protein expression. 1-Monopalmitin can increase drug accumulation by inhibiting P-gp activity in intestinal Caco-2 cells. 1-Monopalmitin has the ability to induce protective autophagy and apoptosis of lung cancer cells (IC50=50-58 μg/mL), with low toxicity to normal cells [1] .
|
-
- HY-Y1004S1
-
|
Decyl alcohol-d<SUB>2SUB>
|
Biochemical Assay Reagents
|
|
|
1-Decanol-d2 is a deuterated 1-Decanol. 1-Decanol is used in the production of lubricants,?surfactants, plasticizers and?solvents. It has also been used to study the thermal properties of polymeric monolithic stationary phases and to enhance homopolyglycine acceptor function. Used in cosmetics, daily flavors, and food flavors.
|
-
- HY-N0210S5
-
-
- HY-W724384
-
-
- HY-W110702S1
-
-
- HY-Y1004S
-
|
Decyl alcohol-d<SUB>3SUB>
|
Biochemical Assay Reagents
|
|
|
1-Decanol-d3 is a deuterated 1-Decanol. 1-Decanol is used in the production of lubricants,?surfactants, plasticizers and?solvents. It has also been used to study the thermal properties of polymeric monolithic stationary phases and to enhance homopolyglycine acceptor function. Used in cosmetics, daily flavors, and food flavors.
|
-
- HY-W111467S
-
-
- HY-W111468S
-
-
- HY-90006S
-
-
- HY-Y1809S1
-
-
- HY-Y1139S
-
|
Heptanedioic acid-d<SUB>4SUB>; 1,5-Pentanedicarboxylic acid-d<SUB>4SUB>; 1,7-Heptanedioic acid-d<SUB>4SUB>
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Pimelic acid-d4 is the deuterium labeled Pimelic acid [1]. Pimelic acid is the organic compound and its derivatives are involved in the biosynthesis of the amino acid called lysine.
|
-
- HY-Y0921S1
-
|
1,2-(RS)-Propanediol-d<SUB>2SUB>; 1,2-Propylene glycol-d<SUB>2SUB>; Propylene glycol-d<SUB>2SUB>
|
Endogenous Metabolite
Isotope-Labeled Compounds
|
Neurological Disease
|
|
(±)-1,2-Propanediol-d2 is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents [1] .
|
-
- HY-Y0921S
-
|
1,2-(RS)-Propanediol-d<SUB>8SUB>; 1,2-Propylene glycol-d<SUB>8SUB>; Propylene glycol-d<SUB>8SUB>
|
Endogenous Metabolite
Isotope-Labeled Compounds
|
Neurological Disease
|
|
(±)-1,2-Propanediol-d8 is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents [1] .
|
-
- HY-Y0921S2
-
|
1,2-(RS)-Propanediol-d<SUB>6SUB>; 1,2-Propylene glycol-d<SUB>6SUB>; Propylene glycol-d<SUB>6SUB>
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Neurological Disease
|
|
(±)-1,2-Propanediol-d6 is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents [1] .
|
-
- HY-W765245
-
|
Sirolimus-13C,d<SUB>3SUB>-1; AY-22989-13C,d<SUB>3SUB>-1
|
Isotope-Labeled Compounds
Fungal
mTOR
Bacterial
Autophagy
Endogenous Metabolite
FKBP
Antibiotic
|
Cancer
|
|
Rapamycin- 13C,d3-1 (Sirolimus- 13C,d3-1) is the deuterium labeled and 13C-labeled Rapamycin (HY-10219). Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1 [1]. Rapamycin is an autophagy activator, an immunosuppressant .
|
-
- HY-113136S
-
|
N1-Methylguanosine-d<SUB>3SUB>
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cancer
|
|
1-Methylguanosine-d3 (N1-Methylguanosine-d3) is deuterium labeled 1-Methylguanosine (HY-113136). 1-Methylguanosine is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker [1] .
|
-
- HY-B0901S1
-
-
- HY-153939S
-
|
RG7388-d<SUB>3SUB>-1
|
Isotope-Labeled Compounds
|
Cancer
|
|
Idasanutlin-d3-1 (RG7388-d3-1) is the deuterium labeled Idasanutlin. Idasanutlin is a potent antagonist of MDM2/p53. Idasanutlin inhibits relapsed or refractory acute myeloid leukemia [1] .
|
-
- HY-19822S1
-
|
RAD1901-d<SUB>4SUB>-1
|
Isotope-Labeled Compounds
Estrogen Receptor/ERR
|
Cancer
|
|
Elacestrant-d4-1 is the deuterium labeled Elacestrant (HY-19822). Elacestrant is an orally available and selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively [1] .
|
-
- HY-W032015S3
-
-
- HY-B0114S1
-
|
GP 47680-d<SUB>4SUB>-1
|
Isotope-Labeled Compounds
Sodium Channel
Apoptosis
|
Neurological Disease
Cancer
|
|
Oxcarbazepine-d4-1 is deuterium labeled Oxcarbazepine. Oxcarbazepine is a sodium channel blocker [1]. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines . Anti-cancer and anticonvulsant effects .
|
-
- HY-W752616
-
|
Monoisopropanolamine-d<SUB>6SUB>
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
1-Aminopropan-2-ol-d6 (Monoisopropanolamine-d6) is the deuterium labeled 1-Aminopropan-2-ol (HY-W015969). 1-Aminopropan-2-ol is a microbial metabolism of amino alcohol metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas [1].
|
-
- HY-W089832S
-
-
- HY-12987S2
-
-
- HY-W711089
-
|
MC-4379-d<SUB>3SUB>-1
|
Isotope-Labeled Compounds
Herbicide
|
Others
|
|
Bifenox-d3-1 (Modown-d3; MC-4379-d3) is the deuterium labeled Bifenox (HY-136513). Bifenox (Modown; MC-4379) is a potent herbicide. Bifenox increases the ROS production. Bifenox causes cellular membrane disruption, inhibition of photosynthesis [1].
|
-
- HY-W099504S
-
-
- HY-B0113S1
-
|
H 16868-d<SUB>3SUB>-1
|
Na+/K+ ATPase
Interleukin Related
Proton Pump
Cytochrome P450
Bacterial
Apoptosis
Autophagy
TNF Receptor
Atg8/LC3
|
Infection
Metabolic Disease
Cancer
|
|
Omeprazole-d3-1 is the deuterium labeled Omeprazole. Omeprazole-1 (H 16868) is an orally active H +,K +-ATPase inhibitor and a proton pump inhibitor. Omeprazole-1 competitively inhibits CYP2C19, CYP3A4, and CYP2C9 activity. Omeprazole-1 inhibits gastric acid secretion and can be used for acid-related gastrointestinal disorders. Omeprazole-1 inhibits pancreatic cancer cell proliferation, induces apoptosis, autophagosome accumulation (elevated LC3-I and LC3-II levels), oxidative stress, and cytogenetic imbalance, modulates lysosomal transport, reduces inflammatory cytokines. Omeprazole-1 alters small intestinal morphology and magnesium absorption, and induces gastric mucosa morphologic changes. Omeprazole-1 aslo has neuroprotective and antibacterial effects [1] .
|
-
- HY-B0561S2
-
-
- HY-W016577S3
-
-
- HY-13956A
-
|
(R)-U 72107-d<SUB>1SUB>
|
Endogenous Metabolite
|
Inflammation/Immunology
|
|
(R)-Pioglitazone-d1 ((R)-U 72107-d1) is a stabilized and deuterated R-enantiomer of pioglitazone, exhibiting pharmacological properties that are beneficial for NASH treatment, including modulation of mitochondrial function, non-steroidal anti-inflammatory effects, and glucose-lowering capabilities.
|
-
- HY-B0258S1
-
-
- HY-B0223S4
-
|
SKF-62979-d<SUB>3SUB>-1
|
Reactive Oxygen Species (ROS)
|
Cancer
|
|
Albendazole-d3-1 (SKF-62979-d3-1) is the deuterium labeled Albendazole (HY-B0223). Albendazole (SKF-62979) is an orally active and broad-spectrum parasiticide with high effectiveness and low host toxicity, is used for the research of gastrointestinal parasites in humans and animals. Albendazole induces apoptosis and autophagy in cancer cells. Albendazole also inhibits tubulin polymerization and HIF-1α, VEGF expression, has antioxidant activity, and inhibits the glycolytic process in cancer cells [1] .
|
-
- HY-14281S2
-
-
- HY-B0196S1
-
-
- HY-W099521S
-
-
- HY-W008625S1
-
-
- HY-15917S1
-
|
DTTl-d<SUB>10SUB>-1
|
Isotope-Labeled Compounds
Disulfidptosis
|
Cancer
|
|
DL-Dithiothreitol-d10-1 is the deuterated form of DL-dithiothreitol. DL-Dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. DL-Dithiothreitol is oxidized to form a stable six-membered ring with an internal disulfide bond [1] .
|
-
- HY-B0451AS3
-
-
- HY-17376S1
-
|
SCH 58235-d<SUB>4SUB>-1
|
Keap1-Nrf2
Autophagy
|
Cardiovascular Disease
Cancer
|
|
Ezetimibe-d4-1 is deuterium labeled Ezetimibe. Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.
|
-
- HY-15780S1
-
|
OPC-34712-d<SUB>8SUB>-1
|
Isotope-Labeled Compounds
Dopamine Receptor
Adrenergic Receptor
5-HT Receptor
|
Neurological Disease
|
|
Brexpiprazole-d8-1 (OPC-34712-d8-1) is the deuterium labeled Brexpiprazole (HY-15780) [1]. Brexpiprazole (OPC-34712), an atypical orally active antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine D2L receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM. Brexpiprazole also shows potent antagonist activity at human noradrenergic α1B (Ki=0.17 nM) and α2C receptors (Ki=0.59 nM) .
|
-
- HY-10846S1
-
|
OPC-67683-d<SUB>4SUB>-1
|
Isotope-Labeled Compounds
|
Cancer
|
|
Delamanid-d4-1 is deuterated labeled Delamanid.Delamanid, a newer mycobacterial cell wall synthesis inhibitor, inhibits the synthesisi of mucolic acids [1].
|
-
- HY-17386S2
-
-
- HY-W032013S2
-
|
Octanol-d<SUB>2SUB>-1
|
Calcium Channel
Endogenous Metabolite
Isotope-Labeled Compounds
|
Others
|
|
1-Octanol-d2-1 is deuterated labeled 1-Octanol (HY-W032013). 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents [1]. 1-Octanol is a highly attractive biofuel with diesel-like properties .
|
-
- HY-14956S1
-
|
TG-873870-d<SUB>3SUB>-1
|
Bacterial
|
Inflammation/Immunology
|
|
Nemonoxacin-d3-1 is the deuterium labeled Nemonoxacin. Nemonoxacin (TG-873870) is an orally active and potent broad-spectrum antibiotic. Nemonoxacin shows good inhibitory activity against different species of staphylococci, streptococci, and enterococci, Neisseria gonorrhoeae, and Haemophilus influenza. Nemonoxacin can be used in the study of bacterial infections and community-acquired pneumonia [1] .
|
-
- HY-W725472
-
-
- HY-17430S1
-
-
- HY-B0197S
-
|
GR-85548A-d<SUB>3SUB>-1
|
5-HT Receptor
|
Cardiovascular Disease
Neurological Disease
Inflammation/Immunology
|
|
Naratriptan-d3 (GR-85548A-d3) is the deuterium labeled Naratriptan (HY-B0197). Naratriptan is a selective 5-HT1B/1D receptor agonist. Naratriptan is peripherally active and has good oral bioavailability, inducing cranial artery vasoconstriction by activating 5-HT1B/1D receptors (EC50=0.11 μM for dog basilar artery). Naratriptan also inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation and reduces sterile inflammation. Naratriptan is mainly used in the research of acute migraine, targeting cranial vascular and neuroinflammatory mechanisms [1] .
|
-
- HY-N1380S4
-
|
2-Methoxyphenol-d<SUB>4SUB>-1
|
COX
NF-κB
Endogenous Metabolite
|
Inflammation/Immunology
|
|
Guaiacol-d4-1 is the deuterium labeled Guaiacol [1]. Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation [1]. Anti-inflammatory activity .
|
-
- HY-W101642S
-
-
- HY-W009450S
-
|
Heptamethylene dibromide-d<SUB>14SUB>
|
Isotope-Labeled Compounds
PROTAC Linkers
|
Cancer
|
|
1,7-Dibromoheptane-d14 (Heptamethylene dibromide-d14) is the deuterium labeled 1,7-Dibromoheptane (HY-W009450). 1,7-Dibromoheptane is a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-76025S
-
|
p-Dibromobenzene-d<SUB>4SUB>
|
Isotope-Labeled Compounds
|
Inflammation/Immunology
|
|
1,4-Dibromobenzene-d4 is a deuterium labeled 1,4-Dibromobenzene. 1,4-Dibromobenzene is used as a fumigant and as a chemical intermediate for pharmaceuticals. Inhalation exposure gives rise to dizziness and chokingwhereas contact with skin or eye produces inflammation and burning in humans [1].
|
-
- HY-113139S
-
|
N1-Methylinosine-d<SUB>3SUB>
|
Isotope-Labeled Compounds
Endogenous Metabolite
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
1-Methylinosine-d3 (N1-MetHYlinosine-d3) is the deuterium labeled 1-Methylinosine. 1-Methylinosine is a modified nucleotide located at position 37 of eukaryotic tRNA, 3' to the tRNA anticodon. 1-Methylinosine is a minor metabolite of 1-methyladenosine (HY-113081). The level of 1-Methylinosine is significantly elevated in urine samples from breast cancer models.
|
-
- HY-109128S2
-
|
MYK-491-d<SUB>3SUB>-1
|
Isotope-Labeled Compounds
Myosin
|
Cardiovascular Disease
|
|
Danicamtiv-d3-1 (MYK-491-d3-1) is a deuterated labeled Danicamtiv (HY-109128). Danicamtiv (MYK-491), an inotropic agent, is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency [1].
|
-
- HY-W723927
-
-
- HY-W014559S3
-
-
- HY-W099504S1
-
-
- HY-10284S3
-
-
- HY-W014286S
-
-
- HY-B0260S6
-
-
- HY-Y1806S1
-
|
Trimethylene dibromide-d<SUB>6SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,3-Dibromopropane-d6 (Trimethylene dibromide-d6) is the deuterium labeled 1,3-Dibromopropane (HY-Y1806). 1,3-Dibromopropane (Trimethylene dibromide) is a standard substrate. 1,3-Dibromopropane can be used for haloalkane dehalogenase DmmA assays.
|
-
- HY-122272S2
-
-
- HY-W012477S
-
|
Photoinitiator-d<SUB>5SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Hydroxycyclohexyl phenyl ketone-d5 (Photoinitiator-184-d5) is the deuterium labeled 1-Hydroxycyclohexyl phenyl ketone (HY-W012477) [1].
|
-
- HY-41676S
-
|
1-Chloro-4-benzonitrile-d<SUB>4SUB>; 1-Chloro-4-cyanobenzene-d<SUB>4SUB>; 1-Cyano-4-chlorobenzene-d<SUB>4SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
4-Chlorobenzonitrile-d4 is the deuterium labeled 4-Chlorobenzonitrile [1].
|
-
- HY-W719338
-
|
(±)-Pentane-1,2-diol<SUB>7SUB>; 1,2-Dihydroxypentane<SUB>7SUB>; 1,2-Pentylene glycol<SUB>7SUB>; Diol PD<SUB>7SUB>; Hydrolite 5<SUB>7SUB>; NSC 513<SUB>7SUB>; 1,2-Pentanediol<SUB>7SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
Pentane-1,2-diol-d7 ((±)-Pentane-1,2-diol-d7; 1,2-Dihydroxypentane-d7; 1,2-Pentylene glycol-d7; Diol PD-d7; Hydrolite 5-d7; NSC 513-d7; 1,2-Pentanediol-d7) is the deuterium labeled Pentane-1,2-diol (HY-Y1249).
|
-
- HY-Y1052S
-
|
1-Dodecylbenzene-d<SUB>30SUB>; 1-Phenyl-n-dodecane-d<SUB>30SUB>; 1-Phenyldodecane-d<SUB>30SUB>; Laurylbenzene-d<SUB>30SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
N-Dodecylbenzene-d30 is the deuterium labeled N-Dodecylbenzene [1].
|
-
- HY-Y0678S
-
|
Trimethyl phloroglucinol-d<SUB>3SUB>
|
Isotope-Labeled Compounds
|
Neurological Disease
|
|
1,3,5-Trimethoxybenzene-d3 (Trimethyl phloroglucinol-d3) is the deuterium labeled 1,3,5-Trimethoxybenzene (HY-Y0678). 1,3,5-Trimethoxybenzene is a key component of the Chinese rose odor. 1,3,5-Trimethoxybenzene is synthesized in three successive methylation steps from phloroglucinol, the initial precursor [1].
|
-
- HY-W004051S
-
-
- HY-N6709S2
-
|
α-Zearalanol-d<SUB>5SUB>-1
|
Isotope-Labeled Compounds
Estrogen Receptor/ERR
|
Endocrinology
|
|
Zeranol-d5-1 (α-Zearalanol-d5-1) is the deuterium labeled Zeranol (HY-N6709). Zeranol, a metabolite of the mycoestrogen zearalenone, is an estrogen receptor agonist. Zeranol is used as a growth promoter of livestock due to its strong estrogenic activity [1] .
|
-
- HY-W013049S4
-
|
Behenic acid-d<SUB>4SUB>-1
|
Isotope-Labeled Compounds
Endogenous Metabolite
DNA/RNA Synthesis
|
Metabolic Disease
Cancer
|
|
Docosanoic acid-d4-1 (Behenic acid-d4-1) is the deuterium labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans [1] .
|
-
- HY-W012856S
-
-
- HY-13631ES2
-
|
MC-GGFG-DXD-d<SUB>4SUB>-1
|
Drug-Linker Conjugates for ADC
Isotope-Labeled Compounds
|
Others
|
|
Deruxtecan-d4-1 is the deuterium labeled Adenosine Deruxtecan (HY-13631E) [1]. Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
|
-
- HY-B0228S
-
-
- HY-N0384S4
-
-
- HY-N0210S11
-
-
- HY-B1812S4
-
|
1,2-Dimethoxybenzene-d<SUB>2SUB>-1
|
Isotope-Labeled Compounds
Cytochrome P450
|
Others
|
|
Veratrole-d2-1 is the deuterium labeled Veratrole (HY-B1812). Veratrole (1,2-Dimethoxybenzene) is a key compound that widely exists in plants and attracts pollinators. The release of Veratrole has a circadian rhythm and plays an important role in plant reproduction, species differentiation, and interactions with pollinators. In addition, Veratrole can be demethylated by cytochrome P-450 in Streptomyces setonii [1] .
|
-
- HY-W142175S
-
|
1-Phenyl-1-butyne-d<SUB>5SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Butynylbenzene-d5 is the deuterium labeled 1-Butynylbenzene [1]. 1-Butynylbenzene-d5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W098448S
-
-
- HY-N0210S7
-
-
- HY-W016931S
-
-
- HY-122277S
-
|
Ro 03-7410-d<SUB>9SUB>
|
Isotope-Labeled Compounds
Drug Metabolite
|
Metabolic Disease
|
|
1'-Hydroxy bufuralol-d9 is a deuterium labeled 1'-Hydroxy bufuralol (HY-122277). 1'-Hydroxy bufuralol is the main metabolite of Bufuralol (HY-105124) by the cytochrome P450 isoenzymes 2D1 and 2D2 (CYP2D1/2). 1'-Hydroxy bufuralol can be used to determine CYP2D1/2 enzyme activity [1] .
|
-
- HY-W017554S
-
-
- HY-W242724
-
-
- HY-N7092S18
-
-
- HY-W130478S
-
-
- HY-W865379
-
-
- HY-W015609S
-
|
2'-Methoxyacetophenone-d<SUB>3SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-(2-Methoxyphenyl)ethanone-d3 (2'-Methoxyacetophenone-d3) is deuterium-labeled 1-(2-Methoxyphenyl)ethanone (HY-W015609) [1].
|
-
- HY-N0210S8
-
-
- HY-W015849S
-
-
- HY-W017522S5
-
|
Hexanedioic acid-d<SUB>4SUB>-1
|
Isotope-Labeled Compounds
Endogenous Metabolite
HSV
|
Infection
Metabolic Disease
|
|
Adipic acid-d4-1 (Hexanedioic acid-d4-1) is the deuterium labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc [1] .
|
-
- HY-34487S3
-
|
Resorcinol dimethyl ether-d<SUB>3SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,3-Dimethoxybenzene-d3 (Resorcinol dimethyl ether-d3) is the deuterium labeled 1,3-Dimethoxybenzene (HY-34487). 1,3-Dimethoxybenzene belongs to the class of organic compounds known as dimethoxybenzenes. 1,3-Dimethoxybenzene is an intermediate in synthesis of organic compounds [1].
|
-
- HY-W724366
-
|
2-Methylethylbenzene-d<SUB>5SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Ethyl-2-methylbenzene-d5 (2-Methylethylbenzene-d5) is the deuterium labeled 1-Ethyl-2-methylbenzene.
|
-
- HY-109506S3
-
|
129Y83-d<SUB>9SUB>-1
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
DPPC-d9-1 is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers [1]. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice .
|
-
- HY-66011AS3
-
|
BAY 12-8039-d<SUB>3SUB>-1
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Moxifloxacin-d3-1 hydrochloride (BAY 12-8039-d3-1) is a deuterium labeled Moxifloxacin (HY-66011A). Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia [1] .
|
-
- HY-W010004S
-
|
3-Chlorobromobenzene-d<SUB>4SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Bromo-3-chlorobenzene-d4 (3-Chlorobromobenzene-d4) is a deuterium labeled 1-Bromo-3-chlorobenzene.
|
-
- HY-W700931
-
|
Dimethylcarbitol-d<SUB>6SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Methoxy-2-(2-methoxyethoxy)ethane-d6 (Dimethylcarbitol-d6) is the deuterium labeled 1-Methoxy-2-(2-methoxyethoxy)ethane (HY-Y1227).
|
-
- HY-W016152S
-
-
- HY-114041S1
-
|
RvE1-d<SUB>4SUB>-1
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Inflammation/Immunology
|
|
Resolvin E1-d4-1 is the deuterium labeled Resolvin E1. Resolvin E1 (RvE1), a potent endogenous pro-resolving mediator of inflammation, is derived from omega-3 fatty acid eicosapentaenoic acid (EPA). Resolvin E1 is endogenously biosynthesized from EPA in the presence of Aspirin during the spontaneous resolution phase of acute inflammation, where specific cell-cell interactions occur. Resolvin E1 possesses unique counterregulatory actions that inhibit polymorphonuclear leukocyte (PMN) transendothelial migration. Resolvin E1 also acts as a potent inhibitor of leukocyte infiltration, dendritic cell migration, and IL-12 production [1] .
|
-
- HY-W342440S
-
-
- HY-107343S1
-
|
Ethyl docosahexaenoate-d<SUB>5SUB>-1
|
Isotope-Labeled Compounds
|
Others
|
|
Docosahexaenoic acid ethyl ester-d5-1 is the deuterium labeled Docosahexaenoic acid ethyl ester. Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) is a 90% concentrated ethyl ester of docosahexaenoic acid manufactured from the microalgal oil. Docosahexaenoic acid ethyl ester enhances 6-hydroxydopamine-induced neuronal damage by induction of lipid peroxidation in mouse striatum. Docosahexaenoic acid (DHA) is a key component of the cell membrane, and its peroxidation is inducible due to the double-bond chemical structure. Docosahexaenoic acid has neuroprotective effects [1] .
|
-
- HY-W725429
-
|
Naphthalene-1,5-diol-d<SUB>6SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,5-Dihydroxynaphthalene-d6 (Naphthalene-1,5-diol-d6) is the deuterium labeled 1,5-Dihydroxynaphthalene (HY-Y0825).
|
-
- HY-Y1805S
-
|
Tetralin solvent-d<SUB>4SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,2,3,4-Tetrahydronaphthalene-d4 (Tetralin solvent-d4) is the deuterium labeled 1,2,3,4-Tetrahydronaphthalene (HY-Y1805) [1].
|
-
- HY-W015301S1
-
|
Hexanedioic acid dimethyl ester-d<SUB>4SUB>-1
|
Isotope-Labeled Compounds
Drug Intermediate
|
Others
|
|
Dimethyl adipate-d4-1 (Hexanedioic acid dimethyl ester-d4-1) is the deuterium labeled Dimethyl adipate (HY-W015301). Dimethyl adipate is an aliphatic dicarboxylate compound. Dimethyl adipate is mainly used as a plasticizer and an intermediate in organic synthesis.
|
-
- HY-W712592
-
|
N-Ethylsuccinimide-d<SUB>5SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Ethylpyrrolidine-2,5-dione-d5 (N-Ethylsuccinimide-d5) is the deuterium labeled 1-Ethylpyrrolidine-2,5-dione (HY-W353513).
|
-
- HY-Y1227S
-
|
Dimethylcarbitol-d<SUB>14SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Methoxy-2-(2-methoxyethoxy)ethane-d14 (Dimethylcarbitol-d14) is the deuterium labeled 1-Methoxy-2-(2-methoxyethoxy)ethane.
|
-
- HY-W094751S
-
-
- HY-W052227S
-
-
- HY-W014409S
-
|
Trimellitic acid-d<SUB>3SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,2,4-Benzenetricarboxylic acid-d3 (Trimellitic acid-d3) is the deuterium labeled 1,2,4-Benzenetricarboxylic acid.
|
-
- HY-W699416
-
|
Naphthalene-1-carboxylic acid-d<SUB>7SUB>
|
Isotope-Labeled Compounds
Biochemical Assay Reagents
|
Others
|
|
1-Naphthoic acid-d7 (Naphthalene-1-carboxylic acid-d7) is the deuterium labeled 1-Naphthoic acid (HY-Y0236). Naphthalene-1-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W724365
-
|
2-Methoxyethyl Bromide-d<SUB>3SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Bromo-2-methoxyethane-d3 (2-Methoxyethyl Bromide-d3) is the deuterium labeled 1-Bromo-2-methoxyethane,98%(stabilized with Na2CO3).
|
-
- HY-W009570S
-
|
P-Bromotrifluoromethoxybenzene-d<SUB>4SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Bromo-4-(trifluoromethoxy)benzene-d4 (P-Bromotrifluoromethoxybenzene-d4) is the deuterium labeled 1-Bromo-4-(trifluoromethoxy)benzene.
|
-
- HY-15025S2
-
|
UK-92480-d<SUB>3SUB>N<SUB>-1
|
Phosphodiesterase (PDE)
|
Cancer
|
|
Sildenafil-d3-1 (UK-92480-d3-1) is deuterium labeled Sildenafil-d3. Sildenafil (UK-92480) is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM.
|
-
- HY-W012934S
-
|
N-Ethyl-pyrrolidone-d<SUB>5SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Ethylpyrrolidin-2-one-d5 (N-Ethyl-pyrrolidone-d5) is deuterium labeled 1-Ethylpyrrolidin-2-one [1].
|
-
- HY-126967AS
-
|
1-P-GPA-d<SUB>9SUB>
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
1-Palmitoyl-sn-glycerol 3-phosphate-d9 is the deuterium labeled 1-Palmitoyl-sn-glycerol 3-phosphate (1-Palmitoyl LPA). 1-Palmitoyl LPA is an analog of LPA that contains palmitic acid at the sn-1 position.
|
-
- HY-112530S
-
|
DSPE-d<SUB>70SUB>
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine-d70 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine. 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (DSPE) is a phosphoethanolamine (PE) lipid that can be used in the synthesis
|
-
- HY-W011883S
-
|
3,5-DIBROMOFLUOROBENZENE-d<SUB>3SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,3-Dibromo-5-fluorobenzene-d3 is the deuterium labeled 1,3-Dibromo-5-fluorobenzene [1].
|
-
- HY-13936S
-
|
1-Methylimidazole-4-acetic acid-d<SUB>3SUB>
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
1-Methylimidazoleacetic acid (1-Methylimidazole-4-acetic acid)-d3 is deuterium labeled 1-Methylimidazoleacetic acid (HY-13936). 1-Methylimidazoleacetic acid is a Histamine (HY-B1204) metabolite. 1-Methylimidazoleacetic acid serves as a biomarker for the detection of mastocytosis [1].
|
-
- HY-113482S
-
-
- HY-Y0566S
-
|
Triethylenediamine-d<SUB>12SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,4-Diazabicyclo[2.2.2]octane-d12 is the deuterium labeled 1,4-Diazabicyclo[2.2.2]octane [1].
|
-
![1,4-Diazabicyclo[2.2.2]octane-d12](//file.medchemexpress.com/product_pic/hy-y0566s.gif)
- HY-W654320
-
-
- HY-11018S1
-
-
- HY-113424AS
-
|
DOPC-d<SUB>9SUB>
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
1,2-Dioleoyl-sn-glycero-3-phosphocholine-d9 is deuterium labeled 1,2-Dioleoyl-sn-glycero-3-phosphocholine. 1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelle
|
-
- HY-W011885S
-
|
N-Lauryl-2-pyrrolidone-d<SUB>6SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Dodecylpyrrolidin-2-one-d6 (N-Lauryl-2-pyrrolidone-d6) is deuterium-labeled 1-Dodecylpyrrolidin-2-one (HY-W011885) [1].
|
-
- HY-N0229S16
-
|
L-2-Aminopropionic acid-d<SUB>3SUB>-1
|
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Alanine-d3-1 is the deuterium labeled L-Alanine [1]. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system .
|
-
- HY-128429S
-
|
(E)-2-Hexenal-d<SUB>2SUB>-1
|
Isotope-Labeled Compounds
Fungal
Biochemical Assay Reagents
|
Infection
|
|
trans-2-Hexenal-d2-1 is the deuterium labeled trans-2-Hexenal (HY-128429). trans-2-Hexenal ((E)-2-Hexenal) is a volatile compound widely present in fresh plants, vegetables, and fruits, with a unique leafy aroma. trans-2-Hexenal has antifungal activity and can also inhibit the germination of soybean seeds and the growth of seedlings. In addition, trans-2-Hexenal can be used to determine low-molecular-weight carbonyl compounds that are reactive with biological nucleophiles in biological samples [1].
|
-
- HY-W740373
-
|
N-Methyl-4-piperidinol-d<SUB>4SUB>
|
Isotope-Labeled Compounds
Biochemical Assay Reagents
|
Others
|
|
1-Methylpiperidin-4-ol-d4 (N-Methyl-4-piperidinol-d4) is the deuterium labeled 1-Methylpiperidin-4-ol (HY-W018626). 1-Methylpiperidin-4-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-N0215S13
-
|
(S)-2-Amino-3-phenylpropionic acid-d<SUB>1SUB>
|
Isotope-Labeled Compounds
Calcium Channel
iGluR
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Phenylalanine-d is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals [1] .
|
-
- HY-W009719S
-
|
2,3-DICHLOROBROMOBENZENE-d<SUB>3SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Bromo-2,3-dichlorobenzene-d3 is the deuterium labeled 1-Bromo-2,3-dichlorobenzene [1].
|
-
- HY-178735S
-
|
DOPC-d<SUB>62SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,2-Dioleoyl-sn-glycero-3-phosphocholine-d62 (DOPC-d62) is the deuterium labeled 1,2-Dioleoyl-sn-glycero-3-phosphocholine.
|
-
- HY-W716213
-
|
2',4'-Dimethoxyacetophenone-d<SUB>6SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-(2,4-Dimethoxyphenyl)ethanone-d6 (2',4'-Dimethoxyacetophenone-d6) is the deuterium labeled 1-(2,4-Dimethoxyphenyl)ethanone (HY-W040456).
|
-
- HY-W009981S
-
|
2,4-Difluorobromobenzene-d<SUB>3SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Bromo-2,4-difluorobenzene-d3 is the deuterium labeled 1-Bromo-2,4-difluorobenzene [1].
|
-
- HY-130462S3
-
|
POPC-d<SUB>64SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d62 (POPC-d64) is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers [1] [1] .
|
-
- HY-B0402S
-
|
1-Adamantanamine-d<SUB>15SUB>; 1-Aminoadamantane-d<SUB>15SUB>
|
Influenza Virus
Orthopoxvirus
SARS-CoV
Apoptosis
|
Infection
Neurological Disease
Cancer
|
|
Amantadine-d15 is the deuterium labeled Amantadine. Amantadine (1-Adamantanamine) is an antiviral agent with activity against influenza A viruses. Amantadine blocks the proton flow through the M2 ion channel (M2 proton channel of influenza A) and thus prevents the release of viral RNA into the cytoplasm of the infected cells. Amantadine is an antiparkinsonian agent [1] .
|
-
- HY-W768340
-
|
D-(+)-Saccharose-13C<SUB>6SUB>-1
|
Isotope-Labeled Compounds
|
Metabolic Disease
Cancer
|
|
Sucrose- 13C6-1 is 13C labeled Sucrose. Sucrose (D-(+)-Saccharose) is a disaccharide which is composed of two monosaccharides, glucose and fructose. Sucrose can be applied in some animal models, including metabolic disease, obesity, diet on preference, and diabetes, et al [1].
|
-
- HY-B0228S8
-
-
- HY-130462S
-
|
POPC-d<SUB>31SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d31 is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for
|
-
- HY-79779S
-
|
α,4-Dibromotoluene-d<SUB>6SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Bromo-4-(bromomethyl)benzene-d6 is the deuterium labeled 1-Bromo-4-(bromomethyl)benzene [1].
|
-
- HY-W766801
-
|
Rac-1-Linoleoyl-3-chloropropanediol-d<SUB>5SUB>
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
1-Linoleoyl-3-chloropropanediol-d5 (Rac-1-Linoleoyl-3-chloropropanediol-d5) is deuterium labeled 1-Linoleoyl-3-chloropropanediol (HY-W777865). 1-Linoleoyl-3-chloropropanediol is a lipid product [1].
|
-
- HY-143671S
-
|
SAPE-d<SUB>11SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Stearoyl-2-arachidonoyl-sn-glycero-3-PE-d11 is the deuterium labeled 1-Stearoyl-2-arachidonoyl-sn-glycero-3-PE [1].
|
-
- HY-130462S1
-
|
POPC-d<SUB>82SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d82 is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for
|
-
- HY-W142820S
-
|
Malonaldehyde Bis(diethyl Acetal)-d<SUB>2SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,1,3,3-Tetraethoxypropane-d2 is the deuterium labeled 1,1,3,3-Tetraethoxypropane [1].
|
-
- HY-W015784S
-
-
- HY-W700950
-
|
1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile-d<SUB>6SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-(4-Chlorophenyl)cyclobutanecarbonitrile-d6 (1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile-d6) is the deuterium labeled 1-(4-Chlorophenyl)cyclobutanecarbonitrile (HY-W010002).
|
-
- HY-B0402S1
-
|
1-Adamantanamine-d<SUB>6SUB>; 1-Aminoadamantane-d<SUB>6SUB>
|
Apoptosis
CDK
SARS-CoV
Bcl-2 Family
Influenza Virus
Orthopoxvirus
|
Cancer
|
|
Amantadine-d6 is the deuterium labeled Amantadine [1]. Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
|
-
- HY-W017142S
-
|
3-(Benzyloxy)-2-propanol-d<SUB>6SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-(Benzyloxy)propan-2-ol-d6 (3-(Benzyloxy)-2-propanol-d6) is the deuterium labeled 1-(Benzyloxy)propan-2-ol (HY-W017142).
|
-
- HY-79779S1
-
|
α,4-Dibromotoluene-d<SUB>4SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Bromo-4-(bromomethyl)benzene-d4 is the deuterium labeled 1-Bromo-4-(bromomethyl)benzene [1].
|
-
- HY-130462S4
-
|
POPC-d<SUB>9SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d9 (POPC-d9) is the deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (HY-130462). 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers [1].
|
-
- HY-W097453S2
-
-
- HY-130462S5
-
|
POPC-d<SUB>62SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d62 (POPC-d62) is the deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (HY-130462). 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers [1].
|
-
- HY-Y0921S3
-
|
1,2-(RS)-Propanediol-13C<SUB>3SUB>; 1,2-Propylene glycol-13C<SUB>3SUB>; Propylene glycol-13C<SUB>3SUB>
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Neurological Disease
|
|
(±)-1,2-Propanediol- 13C3 is 13C labeled (±)-1,2-Propanediol (HY-Y0921). (±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish [1] .
|
-
- HY-125783S1
-
-
- HY-W110726S1
-
-
- HY-178791S
-
|
DH7PE-d<SUB>26SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,2-Diheptanoyl-sn-glycero-3-phosphoethanolamine-d26 (DH7PE-d26) is the deuterium labeled 1,2-Diheptanoyl-sn-glycero-3-phosphoethanolamine.
|
-
- HY-W013376S
-
|
1-(Diphenylmethyl)piperazine-d<SUB>8SUB>; 1-Benzhydrylpiperazine-d<SUB>8SUB>
|
Isotope-Labeled Compounds
|
Cancer
|
|
Norcyclizine-d8 is the deuterium labeled Norcyclizine [1].
|
-
- HY-125783S
-
-
- HY-107737S3
-
|
1,2-Dilauroyl-sn-glycero-3-phosphocholine-d<SUB>9SUB>
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
1,2-DLPC-d9 (1,2-Dilauroyl-sn-glycero-3-phosphocholine-d9) is the deuterium labeled 1,2-DLPC. 1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. 1,2-DLPC is a phospholipid used in the synthesis of liposomes. 1,2-DLPC enhances fat breakdown and apoptosis in fat cells through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance through PPARα-mediated inflammation in muscle cells [1] .
|
-
- HY-W110726S
-
-
- HY-125783S2
-
-
- HY-W777094
-
|
Tetraethoxy C methyl propane-d<SUB>8SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Acetyl-4-(4-hydroxyphenyl)piperazine-d8 (Tetraethoxy C methyl propane-d8) is the deuterium labeled 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone (HY-W014037).
|
-
- HY-W590534S
-
-
- HY-107737S2
-
|
1,2-Dilauroyl-sn-glycero-3-phosphocholine-d<SUB>46SUB>
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
1,2-DLPC-d46 (1,2-Dilauroyl-sn-glycero-3-phosphocholine-d46) is the deuterium labeled 1,2-DLPC. 1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. 1,2-DLPC is a phospholipid used in the synthesis of liposomes. 1,2-DLPC enhances fat breakdown and apoptosis in fat cells through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance through PPARα-mediated inflammation in muscle cells [1] .
|
-
- HY-W1115209
-
|
2,4,6-Tribromoiodobenzene-d<SUB>2SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,3,5-Tribromo-2-iodobenzene-d2 (2,4,6-Tribromoiodobenzene-d2) is a deuterium labeled 1,3,5-Tribromo-2-iodobenzene.
|
-
- HY-W105111S
-
|
2,3,5-Trichlorobromobenzene-d<SUB>2SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Bromo-2,3,5-trichlorobenzene-d2 is the deuterium labeled 1-Bromo-2,3,5-trichlorobenzene [1].
|
-
- HY-W014431S
-
|
3-Fluoro-5-bromochlorobenzene-d<SUB>3SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Bromo-3-chloro-5-fluorobenzene-d3 is the deuterium labeled 1-Bromo-3-chloro-5-fluorobenzene [1].
|
-
- HY-W015824S3
-
-
- HY-N0210S12
-
-
- HY-107737S
-
|
1,2-Dilauroyl-sn-glycero-3-phosphocholine-d<SUB>55SUB>
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
1,2-DLPC-d55 (1,2-Dilauroyl-sn-glycero-3-phosphocholine-d55) is the deuterium labeled 1,2-DLPC. 1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. 1,2-DLPC is a phospholipid used in the synthesis of liposomes. 1,2-DLPC enhances fat breakdown and apoptosis in fat cells through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance through PPARα-mediated inflammation in muscle cells [1] .
|
-
- HY-N7092S23
-
|
D(-)-Fructose-13C<SUB>3SUB>-1
|
Isotope-Labeled Compounds
|
Others
|
|
D-Fructose- 13C3-1 is 13C-labeled D-Fructose (HY-N7092). D-Fructose (D(-)-Fructose) is a natural monosaccharide found in many plants.
|
-
- HY-B0151S2
-
|
3β-Hydroxy-5-pregnen-20-one-d<SUB>4SUB>-1
|
Cannabinoid Receptor
TRP Channel
Endogenous Metabolite
Autophagy
|
Neurological Disease
|
|
Pregnenolone-d4-1 is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication [1] . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
|
-
- HY-145473S
-
|
15(S)-HETE-SAPE; 15(S)-Hydroxyeicosatetraenoic acid-SAPE-d<SUB>11SUB>; 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-Phosphatidylethanolamine-d<SUB>11SUB>
|
Isotope-Labeled Compounds
Others
|
Metabolic Disease
|
|
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11 (15(S)-HETE-SAPE-d11) is deuterium labeled 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE. 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (HY-B2219) at the sn-1 position and 15(S)-HETE at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 (HY-N6687) by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE) by 15-LO. Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes [1].
|
-
- HY-W013504S
-
|
4-Bromo-α,α,α-trifluorotoluene-d<SUB>4SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Bromo-4-(trifluoromethyl)benzene-d4 is the deuterium labeled 1-Bromo-4-(trifluoromethyl)benzene [1].
|
-
- HY-B0896S2
-
|
Glyceryl triacetate-d<SUB>9SUB>; 1,2,3-Triacetoxypropane-d<SUB>9SUB>
|
Fungal
Endogenous Metabolite
|
Others
|
|
Glyceryl Triacetate-d9 is the deuterium labeled Triacetin [1]. Triacetin is an artificial chemical compound, is the triester of glycerol and acetic acid, and is the second simplest fat after triformin.
|
-
- HY-W654064
-
-
- HY-Y1275S
-
|
NMP-d<SUB>9SUB>; 1-Methyl-2-pyrrolidinone-d<SUB>9SUB>
|
Isotope-Labeled Compounds
Biochemical Assay Reagents
|
Cancer
|
|
N-Methylpyrrolidone-d9 (NMP-d9) is deuterium labeled N-Methylpyrrolidone. N-Methylpyrrolidone (1-Methyl-2-pyrrolidinone), a five-membered cyclic amide, is an orally active organic polar solvent with teratogenicity and toxicity. N-Methylpyrrolidone is low in acute toxicity with a LD50 value of 3914 mg/kg in rats and of 4050 mg/kg in mice. N-Methylpyrrolidone is extensively used in the manufacture of adhesives, paints, fuels, and pharmaceuticals [1] .
|
-
- HY-W192474S
-
-
- HY-Y0743S
-
-
- HY-W013948S
-
|
Propanal, (2,4-dinitrophenyl)hydrazone-d<SUB>3SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-(2,4-Dinitrophenyl)-2-propylidenehydrazine-d3 is the deuterium labeled 1-(2,4-Dinitrophenyl)-2-propylidenehydrazine [1].
|
-
- HY-W654409
-
|
Hexafluoroisopropyl alcohol-d<SUB>2SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,1,1,3,3,3-Hexafluoropropan-2-ol-d2 (Hexafluoroisopropyl alcohol-d2) is deuterium labeled 1,1,1,3,3,3-Hexafluoropropan-2-ol [1].
|
-
- HY-112675S
-
|
4-OI-13C<SUB>5SUB>-1
|
Isotope-Labeled Compounds
|
Others
|
|
4-Octyl itaconate- 13C5-1 is 13C-labeled 4-Octyl itaconate (HY-112675). Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
|
-
- HY-Y0219S1
-
-
- HY-B0896S1
-
|
Glyceryl triacetate-d<SUB>5SUB>; 1,2,3-Triacetoxypropane-d<SUB>5SUB>
|
Isotope-Labeled Compounds
Fungal
Endogenous Metabolite
|
Others
|
|
Triacetin-d5 is the deuterium labeled Triacetin. Triacetin is an artificial chemical compound, is the triester of glycerol and acetic acid, and is the second simplest fat after triformin.
|
-
- HY-W009293S
-
|
N-(4,4-Difluorobenzhydryl)piperazine-d<SUB>4SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-(Bis(4-fluorophenyl)methyl)piperazine-d4 (N-(4,4-Difluorobenzhydryl)piperazine-d4) is the deuterium labeled 1-(Bis(4-fluorophenyl)methyl)piperazine.
|
-
- HY-W777599
-
|
(Rac)-Naproxen-13C,d<SUB>3SUB>-1
|
Isotope-Labeled Compounds
|
Others
|
|
(±)-Naproxen- 13C,d3-1 ((Rac)-Naproxen- 13C,d3-1) is 13C and deuterium labeled (±)-Naproxen [1].
|
-
- HY-122426S2
-
|
Undecyl bromide-d<SUB>4SUB>; undecane, 1-bromo-d<SUB>4SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Bromoundecane-d4 is the deuterium labeled 1-Bromoundecane [1].
|
-
- HY-W756596
-
|
3-Chloropropane-1,2-diyl dioctanoate-d<SUB>5SUB>
|
Isotope-Labeled Compounds
Others
|
Metabolic Disease
|
|
1,2-Dioctanoyl-3-chloropropanediol-d5 is deuterium labeled 1,2-Dioctanoyl-3-chloropropanediol. 1,2-Dioctanoyl-3-chloropropanediol (3-Chloropropane-1,2-diyl dioctanoate) is an ester product [1].
|
-
- HY-W012652S
-
|
Quinoxaline, 1,2,3,4-tetrahydro-d<SUB>4SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,2,3,4-Tetrahydroquinoxaline-d4 (Quinoxaline, 1,2,3,4-tetrahydro-d4) is the deuterium labeled 1,2,3,4-Tetrahydroquinoxaline.
|
-
- HY-Y0531S
-
|
Tricyclo[3.3.1.1~3,7~]decan-1-ol-d<SUB>15SUB>
|
Isotope-Labeled Compounds
Drug Intermediate
Bacterial
|
Infection
|
|
1-Adamantanol-d15 (Tricyclo[3.3.1.1~3,7~]decan-1-ol-d15) is the deuterium labeled 1-Adamantanol (HY-Y0531). 1-Adamantanol (Tricyclo[3.3.1.1~3,7~]decan-1-ol) is a hydroxylated derivative of Adamantane (HY-N2427). 1-Adamantanol serves as a substrate for regioselective hydroxylation reactions in Streptomyces strain SA8. 1-Adamantanol can form acrylate derivatives, which are used as photoresist layer materials [1].
|
-
- HY-N0537S12
-
-
- HY-125783S3
-
-
- HY-N0229S4
-
|
L-2-Aminopropionic acid-13C,d<SUB>1SUB>
|
Endogenous Metabolite
|
Neurological Disease
Metabolic Disease
|
|
L-Alanine- 13C,d is the 13C- and deuterium labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
|
-
- HY-D0837S
-
|
Glyoxaline-d<SUB>4SUB>; 1,3-Diaza-2,4-cyclopentadiene-d<SUB>4SUB>
|
Endogenous Metabolite
|
Others
|
|
Imidazole-d4 is the deuterium labeled Imidazole [1].
|
-
- HY-115702S
-
|
(Rac)-PAF (C16)-d<SUB>4SUB>
|
Isotope-Labeled Compounds
Endogenous Metabolite
Platelet-activating Factor Receptor (PAFR)
|
Inflammation/Immunology
|
|
1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine-d4 ((Rac)-PAF (C16)-d4) is the deuterium labeled 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine is an endogenous inflammatory lipid mediator. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine acts as a high-affinity agonist for PAFR (GPCR), inducing platelet aggregation, vascular permeability, and leukocyte chemotaxis at extremely low concentrations. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine exerts its effects via cell surface receptors to regulate inflammation [1].
|
-
- HY-W051547S1
-
|
2-Chloro-3-(1-hydroxyethyl)pyridin-d<SUB>3SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-(2-Chloropyridin-3-yl)ethanol-d3 (2-Chloro-3-(1-hydroxyethyl)pyridin-d3) is the deuterium labeled 1-(2-Chloropyridin-3-yl)ethanol.
|
-
- HY-N0537S13
-
-
- HY-10002AS2
-
|
1α,25-Dihydroxy-3-epi-vitamin D3-d<SUB>6SUB>
|
Isotope-Labeled Compounds
VD/VDR
|
Others
|
|
(1S)-Calcitriol-d6 (1α,25-Dihydroxy-3-epi-vitamin D3-d6) is the deuterium labeled (1S)-Calcitriol (HY-10002A). (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion [1].
|
-
- HY-10003S
-
|
1-hydroxycholecalciferol-d<SUB>7SUB>; 1.alpha.-Hydroxyvitamin D3-d<SUB>7SUB>
|
Isotope-Labeled Compounds
VD/VDR
|
Metabolic Disease
|
|
Alfacalcidol-d7 is the deuterium labeled Alfacalcidol. Alfacalcidol (1-hydroxycholecalciferol) is a vitamin D active metabolites, acts as a non-selective VDR activator medication, and widely be used in the management of osteoporosis [1] .
|
-
- HY-W754348
-
|
1-(2,6-Dimethylphenoxy)acetone-d<SUB>5SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-(2,6-Dimethylphenoxy)propan-2-one-d5 (1-(2,6-Dimethylphenoxy)acetone-d5) is the deuterium labeled 1-(2,6-Dimethylphenoxy)propan-2-one (HY-W270592).
|
-
- HY-15029S1
-
-
- HY-W051547S
-
|
2-Chloro-3-(1-hydroxyethyl)pyridine-d<SUB>4SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-(2-Chloropyridin-3-yl)ethanol-d4 (2-Chloro-3-(1-hydroxyethyl)pyridine-d4) is the deuterium labeled 1-(2-Chloropyridin-3-yl)ethanol.
|
-
- HY-10002AS
-
|
1α,25-Dihydroxy-3-epi-vitamin D3-d<SUB>3SUB>
|
Isotope-Labeled Compounds
VD/VDR
|
Others
|
|
(1S)-Calcitriol-d3 (1α,25-Dihydroxy-3-epi-vitamin D3-d3) is the deuterium labeled (1S)-Calcitriol (HY-10002A). (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion [1].
|
-
- HY-Y0479S3
-
-
- HY-146829S
-
|
15:0-18:1-PA-d<SUB>7SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphate-d7 (sodium) is deuterium labeled 1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphate (sodium).
|
-
- HY-W768181
-
-
- HY-142555S
-
|
Sodium 4-[1-(4-hydroxyphenyl)-1-methylethyl]phenyl sulfate-d<SUB>6SUB> (1:1)
|
Isotope-Labeled Compounds
|
Others
|
|
Bisphenol A monosulfate-d6 (sodium) is the deuterium labeled Bisphenol A monosulfate sodium [1].
|
-
- HY-100441S1
-
-
- HY-W654074
-
|
1,1′-[1-(Chloromethyl)-1,2-ethanediyl] didodecanoate-d<SUB>5SUB>
|
Isotope-Labeled Compounds
Biochemical Assay Reagents
|
Metabolic Disease
|
|
1,2-Dilauroyl-3-chloropropanediol-d5 (1,1′-[1-(Chloromethyl)-1,2-ethanediyl] didodecanoate-d5) is the deuterium labeled 1,2-Dilauroyl-3-chloropropanediol (HY-W587507). 1,2-Dilauroyl-3-chloropropanediol (1,1′-[1-(Chloromethyl)-1,2-ethanediyl] didodecanoate) is an ester product.
|
-
- HY-112005S
-
|
Dioleoylphosphatidylethanolamine-d<SUB>62SUB>; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-d<SUB>62SUB>
|
Isotope-Labeled Compounds
|
Inflammation/Immunology
|
|
DOPE-d62 (Dioleoylphosphatidylethanolamine-d62) is the deuterium labeled DOPE (HY-112005). DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA [1].
|
-
- HY-W010265S
-
|
1-Phenylbutan-1-one-d<SUB>5SUB>; 1-Phenyl-1-butanone-d<SUB>5SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
Butyrophenone-d5 is the deuterium labeled Butyrophenone [1].
|
-
- HY-W767978
-
|
6-Acetyl-4,4-dimethylthio-chroman-d<SUB>8SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-(4,4-Dimethylthiochroman-6-yl)ethanone-d8 (6-Acetyl-4,4-dimethylthio-chroman-d8) is the deuterium labeled 1-(4,4-Dimethylthiochroman-6-yl)ethanone (HY-I0187).
|
-
- HY-178810S
-
|
DOPS-NH3-d<SUB>62SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,2-Dioleoyl-sn-glycero-3-phospho-L-serine-d62 ammonium (DOPS-NH3-d62) is the deuterium labeled 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine ammonium.
|
-
- HY-130462S2
-
|
POPC-13C<SUB>16SUB>
|
Isotope-Labeled Compounds
Liposome
|
Others
|
|
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC- 13C16 (POPC- 13C16) is 13C labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers [1] [1] .
|
-
- HY-178403S
-
|
N,N-Diethyl-N,N-diphenylurea-d<SUB>10SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,3-Diethyl-1,3-diphenylurea-d10-1 (N,N-Diethyl-N,N-diphenylurea-d10-1) is the deuterium labeled 1,3-Diethyl-1,3-diphenylurea.
|
-
- HY-W770203
-
|
DG(18:1/0:0/18:2)-d<SUB>5SUB>
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
1-Oleoyl-2-linoleoyl-rac-glycerol-d5 (DG(18:1/0:0/18:2)-d5) is the deuterium labeled 1-Oleoyl-2-linoleoyl-rac-glycerol (HY-W777107). 1-Oleoyl-2-linoleoyl-rac-glycerol (DG(18:1/0:0/18:2)) is a diacylglycerol, which is composed of a linoleic acid and an oleic acid. 1-Oleoyl-2-linoleoyl-rac-glycerol can be found in dry-cured ham, and acts as the food additive [1].
|
-
- HY-B0456S1
-
|
Vitamin B2-13C<SUB>4SUB>,15N<SUB>2SUB>-1; E101-13C<SUB>4SUB>,15N<SUB>2SUB>-1
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Riboflavin-5-Phosphate- 13C4, 15N2-1 is the 13C-labeled and 15N-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
|
-
- HY-W101971S
-
|
1-(4-Chlorophenyl)-2-methyl-2-propanol-d<SUB>6SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-(4-Chlorophenyl)-2-methylpropan-2-ol-d6 (1-(4-Chlorophenyl)-2-methyl-2-propanol-d6) is the deuterium labeled 1-(4-Chlorophenyl)-2-methylpropan-2-ol (HY-W101971).
|
-
- HY-Y1039S
-
|
1-Monostearin-d<SUB>40SUB>; 2,3-dihydroxypropyl stearate-d<SUB>40SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Stearoyl-rac-glycerol-d40 is the deuterium labeled 1-Stearoyl-rac-glycerol [1].
|
-
- HY-109541S5
-
|
DMPC-d<SUB>67SUB>; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d<SUB>67SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d67 is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine
|
-
- HY-W743123
-
|
1,3-Dipalmitoylglycerol-d<SUB>5SUB>; Glycerol 1,3-dipalmitate-d<SUB>5SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,3-Dipalmitin-d5 (1,3-Dipalmitoylglycerol-d5) is a deuterium labeled 1,3-Dipalmitin (HY-128792). 1,3-Dipalmitin (1,3-Dipalmitoylglycerol) is a cerebroside that can be found in Typhonium giganteum Engl [1].
|
-
- HY-109541S3
-
|
DMPC-d<SUB>13SUB>; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d<SUB>13SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
Colfosceril miristate-d13 (DMPC-d13) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery [1] .
|
-
- HY-N0229S19
-
-
- HY-B0166S8
-
|
L-Ascorbate-1; Vitamin C-13C<SUB>6SUB>-1
|
Isotope-Labeled Compounds
Endogenous Metabolite
Reactive Oxygen Species (ROS)
Calcium Channel
Apoptosis
|
Cancer
|
|
L-Ascorbic acid- 13C6-1 (L-Ascorbate-1; Vitamin C- 13C6-1) is a 13C labeled L-Ascorbic acid (HY-B0166) [1]. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
|
-
- HY-109541S
-
|
DMPC-d<SUB>58SUB>; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d<SUB>58SUB>
|
Isotope-Labeled Compounds
|
Cancer
|
|
Colfosceril miristate-d58 (DMPC-d58) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery [1] .
|
-
- HY-Y1039S1
-
|
1-Monostearin-d<SUB>35SUB>; 2,3-dihydroxypropyl stearate-d<SUB>35SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Stearoyl-rac-glycerol-d35 is the deuterium labeled 1-Stearoyl-rac-glycerol.
|
-
- HY-W751665
-
|
N-Benzyl-3-carboethoxy-4-piperidone hydrochloride-d<SUB>3SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-(Adamantan-1-yl)ethan-1-one-d3 (N-Benzyl-3-carboethoxy-4-piperidone hydrochloride-d3) is the deuterium labeled 1-(Adamantan-1-yl)ethan-1-one (HY-W067624).
|
-
- HY-109541S1
-
|
DMPC-d<SUB>4SUB>; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d<SUB>4SUB>
|
Isotope-Labeled Compounds
|
Cancer
|
|
Colfosceril miristate-d4 (DMPC-d4) is deuterium labeled Colfosceril miristate. Colfosceril miristate is a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery [1] .
|
-
- HY-109541S4
-
|
DMPC-d<SUB>63SUB>; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d<SUB>63SUB>
|
Isotope-Labeled Compounds
|
Cancer
|
|
Colfosceril miristate-d63 (DMPC-d63) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery [1] .
|
-
- HY-109541S2
-
|
DMPC-d<SUB>9SUB>; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d<SUB>9SUB>
|
Isotope-Labeled Compounds
|
Cancer
|
|
Colfosceril miristate-d9 (DMPC-d9) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery [1] .
|
-
- HY-Y1217S1
-
|
Hydroxycyclohexane-d<SUB>11SUB>; NSC 54711-d<SUB>11SUB>; Naxol-d<SUB>11SUB>
|
Isotope-Labeled Compounds
Biochemical Assay Reagents
Environmental Pollutants
|
Endocrinology
|
|
1-Cyclohexanol11 (Hydroxycyclohexane11; NSC 5471111) is the deuterium labeled 1-Cyclohexanol (HY-Y1217). 1-Cyclohexanol is an orally active Cramer Class I flavor ingredient that can be used in fragrances. 1-Cyclohexanol has a wide margin of safety and is environmentally friendly.
|
-
- HY-114553S
-
|
5F-PB-223-Carboxyindolemetabolite-d<SUB>5SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-(5-Fluoropentyl)-1H-indole-3-carboxylic acid-d5 (5F-PB-223-Carboxyindolemetabolite-d5) is deuterium labeled 1-(5-Fluoropentyl)-1H-indole-3-carboxylic acid [1].
|
-
- HY-W777649
-
-
- HY-Y1217S
-
|
Hydroxycyclohexane-d<SUB>12SUB>; NSC 54711-d<SUB>12SUB>; Naxol-d<SUB>12SUB>
|
Isotope-Labeled Compounds
Biochemical Assay Reagents
Environmental Pollutants
|
Endocrinology
|
|
1-Cyclohexanol12 (Hydroxycyclohexane12; NSC 5471112) is the deuterium labeled 1-Cyclohexanol (HY-Y1217). 1-Cyclohexanol is an orally active Cramer Class I flavor ingredient that can be used in fragrances. 1-Cyclohexanol has a wide margin of safety and is environmentally friendly.
|
-
- HY-W005926S
-
|
1,5-Dimethylpyrazole-4-carboxylic acid-d<SUB>6SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,5-Dimethyl-1H-pyrazole-4-carboxylic acid-d6 (1,5-Dimethylpyrazole-4-carboxylic acid-d6) is the deuterium labeled 1,5-Dimethyl-1H-pyrazole-4-carboxylic acid.
|
-
- HY-78004S1
-
|
Dibenzil-d<SUB>4SUB>; s-Diphenylethane-d<SUB>4SUB>; Bibenzyl-d<SUB>4SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,2-Diphenylethane-d4 (Dibenzil-d4; s-Diphenylethane-d4; Bibenzyl-d4) is the deuterium labeled Bibenzyl (HY-78004) [1].
|
-
- HY-W777620
-
|
rac-Cotinine-13C,d<SUB>3SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone- 13C,d3 (rac-Cotinine- 13C,d3) is the deuterium and 13C-labeled 1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone (HY-W588192).
|
-
- HY-12516S2
-
|
Org-2969-13C<SUB>2SUB>,d<SUB>2SUB>-1
|
Isotope-Labeled Compounds
Progesterone Receptor
|
Others
|
|
Desogestrel- 13C2,d2-1 (Org-2969- 13C2,d2-1) is the deuterium labeled and 13C-labeled Desogestrel (HY-12516). Desogestrel (Org-2969) is a third-generation progesterone analogue contained in many oral contraceptive preparations. Desogestrel is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups [1] .
|
-
- HY-Y1641S
-
|
Ethylene dithioglycol-d<SUB>4SUB>; Ethylene glycol-d4, dithio-; Ethylenedithiol-d<SUB>4SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,2-Ethanedithiol-d4 is the deuterium labeled 1,2-Ethanedithiol [1].
|
-
- HY-W709612
-
|
N-Desmethyl regorafenib N-oxide-d<SUB>3SUB>-1
|
Isotope-Labeled Compounds
VEGFR
Raf
c-Kit
Drug Metabolite
|
Cancer
|
|
Regorafenib N-oxide and N-desmethyl (M5)-d3-1 (N-Desmethyl regorafenib N-oxide-d3-1) is the deuterium labeled Regorafenib N-oxide and N-desmethyl (M5) (HY-108226). Regorafenib N-oxide and N-desmethyl (M5) (N-Desmethyl regorafenib N-oxide) is an active metabolite of Sorafenib (HY-10201) and can be metabolized by CYP3A4 [1].
|
-
- HY-W392083S1
-
|
(1,3E,5Z)-UNDECATRIENE-d<SUB>5SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
(1,3E,5Z)-Undeca-1,3,5-triene-d5 is deuterated labeled (1,3E,5Z)-Undeca-1,3,5-triene.
|
-
- HY-Y1309S1
-
|
Furro ER-d<SUB>7SUB>; NSC 9586-d<SUB>7SUB>; Nako TRB-d<SUB>7SUB>
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
1-Naphthol-d7 (Furro ER-d7) is the deuterium labeled Naphthol (HY-Y1309). 1-Naphthol (Furro ER) is an excited state proton transfer (ESPT) fluorescent molecular probe. 1-naphthol can sense the hydrophobic domains in micellar aggregation and accurately sense the sol-gel transition. 1-naphthol can be used to study the thermally induced microenvironmental changes and hydration levels of Pluronic F127 (PF127) in different microenvironments in aqueous media [1].
|
-
- HY-W392083S
-
|
(1,3E,5E)-UNDECATRIENE-d<SUB>5SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
(1,3E,5E)-Undeca-1,3,5-triene-d5 is deuterated labeled (1,3E,5E)-Undeca-1,3,5-triene.
|
-
- HY-Y1309S
-
|
Furro ER-d<SUB>8SUB>; NSC 9586-d<SUB>8SUB>; Nako TRB-d<SUB>8SUB>
|
Endogenous Metabolite
|
Others
|
|
1-Naphthol-d8 is the deuterium labeled 1-Naphthol [1]. 1-naphthol is an excited state proton transfer (ESPT) fluorescent molecular probe .
|
-
- HY-W718041S
-
|
3-Chloro-2-(decanoyloxy)propyl dodecanoate-13C<SUB>3SUB>
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
1-Lauroyl-2-decanoyl-3-chloropropanediol-13C3 is an isotope labeled 3-monochloropropanediol (3-MCPD) glycidyl ester.
|
-
- HY-W050145S
-
|
1,6-Anhydro-β-D-glucopyranose-d<SUB>7SUB>; 1,6-Anhydro-β-D-glucose-d<SUB>7SUB>
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
Levoglucosan-d7 is the deuterium labeled Levoglucosan. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature [1] .
|
-
- HY-146726S
-
|
TG(15:0/15:0/15:0)-d<SUB>29SUB>; 1,2,3-Tripentadecanoyl glycerol-d<SUB>29SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
Tripentadecanoin-d29 is the deuterium labeled Tripentadecanoin.
|
-
- HY-125771S
-
|
18:0 Lyso-PC-d<SUB>35SUB>; LPC(18:0)-d<SUB>35SUB>
|
Isotope-Labeled Compounds
Endogenous Metabolite
HDAC
STAT
Apoptosis
|
Cancer
|
|
1-Stearoyl-sn-glycero-3-phosphocholine-d35 is deuterium labeled 1-Stearoyl-sn-glycero-3-phosphocholine (HY-125771). 1-Stearoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine that inhibits HDAC3 activity and phosphorylation of STAT3 in K562 cells. 1-Stearoyl-sn-glycero-3-phosphocholine induces apoptosis and exhibits anticancer activity in chronic myelogenous leukemia (CML) K562 cells [1].
|
-
- HY-146737S
-
|
TG(15:0/15:0/15:0)-d<SUB>5SUB>; 1,2,3-Tripentadecanoyl glycerol-d<SUB>5SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
Tripentadecanoin-d5 is the deuterium labeled Tripentadecanoin.
|
-
- HY-178758S
-
|
PSPC-d<SUB>66SUB>; PC(16:0-18:0)-d<SUB>66SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Palmitoyl-2-stearoyl-sn-glycero-3-phosphocholine-d66 (PSPC-d66) is the deuterium labeled 1-Palmitoyl-2-stearoyl-sn-glycero-3-phosphocholine.
|
-
- HY-Y0727S
-
|
1,5-Pentanedibromide-d<SUB>4SUB>; Pentamethylene bromide-d<SUB>4SUB>; Pentamethylene dibromide-d<SUB>4SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,5-Dibromopentane-d4 is the deuterium labeled 1,5-Dibromopentane [1].
|
-
- HY-W726845
-
|
MNP-d<SUB>11SUB>; MeNP-d<SUB>11SUB>; N-Methyl-N'-nitrosopiperazine-d<SUB>11SUB>
|
Isotope-Labeled Compounds
Biochemical Assay Reagents
|
Others
|
|
1-Methyl-4-nitrosopiperazine-d11 (MNP-d11) is the deuterium labeled 1-Methyl-4-nitrosopiperazine (HY-W663740). 1-Methyl-4-nitrosopiperazine (MNP; MeNP;N-Methyl-N'-nitrosopiperazine) is a potential impurity in sartans, non-steroidal anti-inflammatory drugs (NSAIDs), and thiazide diuretics [1].
|
-
- HY-34444S
-
|
Bondelane A-d<SUB>8SUB>; Cyclic tetramethylene sulfone-d<SUB>8SUB>; Cyclotetramethylene sulfone-d<SUB>8SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,1-Dioxothiolan-d8 is the deuterium labeled 1,1-Dioxothiolan [1].
|
-
- HY-W048482S
-
|
DMT-2'O-TBDMS-rU phosphoramidite-13C<SUB>2SUB>,d<SUB>1SUB>
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
|
Others
|
|
rU Phosphoramidite- 13C2,d1 (DMT-2'O-TBDMS-rU phosphoramidite- 13C2,d1) is deuterium and 13C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
- HY-W777706
-
|
1-(3,4-Dimethylphenyl)ethanol-13C,d<SUB>3SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-(3,4-Dimethylphenyl)ethan-1-ol- 13C,d3 (1-(3,4-Dimethylphenyl)ethanol- 13C,d3) is the deuterium labeled and 13C-labeled 1-(3,4-Dimethylphenyl)ethan-1-ol (HY-W340128).
|
-
- HY-Y0727S1
-
|
1,5-Pentanedibromide-d<SUB>10SUB>; Pentamethylene bromide-d<SUB>10SUB>; Pentamethylene dibromide-d<SUB>10SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,5-Dibromopentane-d10 is the deuterium labeled 1,5-Dibromopentane [1].
|
-
- HY-128792S
-
|
Glyceryl 1,3-dipalmitate-d6; 1,3-Dipalmitoyl-glycerol-d6; Glycerol 1,3-Dipalmitate-d<SUB>62SUB>
|
Isotope-Labeled Compounds
Biochemical Assay Reagents
|
Others
|
|
1,3-Dipalmitin-d6 (1,3-Dipalmitoylglycerol-d6) is deuterium labeled 1,3-Dipalmitin (HY-128792). 1,3-Dipalmitin (1,3-Dipalmitoylglycerol) is a diacylglycerol compound that can be found in the tuberous roots of Typhonium giganteum Engl. 1,3-Dipalmitin acts as an adsorption inhibitor for 1,3-diglycerides and β-carotene [1] .
|
-
- HY-W040193S1
-
|
1,2-Distearoyl-sn-glycero-3-PC-d<SUB>74SUB>; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d<SUB>74SUB>
|
Isotope-Labeled Compounds
Liposome
|
Others
|
|
DSPC-d74 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system [1] .
|
-
- HY-Y1044S
-
|
1,5-Pentamethylene glycol-d<SUB>10SUB>; Pentamethylene glycol-d<SUB>10SUB>; Pentylene glycol-d<SUB>10SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,5-Dihydroxypentane-d10 is the deuterium labeled 1,5-Dihydroxypentane [1].
|
-
- HY-Y0093S
-
|
α,ω-Nonanediol-d<SUB>14SUB>; 1,9-Dihydroxynonane-d<SUB>14SUB>; Nonamethylene Glycol-d<SUB>14SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
NSC 5416-d14 is the deuterium labeled NSC 5416 [1].
|
-
- HY-W040193S
-
|
1,2-Distearoyl-sn-glycero-3-PC-d<SUB>70SUB>; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d<SUB>70SUB>
|
Isotope-Labeled Compounds
Liposome
|
Others
|
|
DSPC-d70 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system [1] .
|
-
- HY-W040193S6
-
|
1,2-Distearoyl-sn-glycero-3-PC-d<SUB>13SUB>; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d<SUB>13SUB>
|
Isotope-Labeled Compounds
Liposome
|
Others
|
|
DSPC-d13 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d13) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system [1] .
|
-
- HY-W040193S2
-
|
1,2-Distearoyl-sn-glycero-3-PC-d<SUB>79SUB>; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d<SUB>79SUB>
|
Isotope-Labeled Compounds
Liposome
|
Others
|
|
DSPC-d79 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d79) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system [1] .
|
-
- HY-W749377
-
|
Toluene, 2,3,4,5,6-pentabromo-13C<SUB>6SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,2,3,4,5-Pentabromo-6-methylbenzene- 13C6 (Toluene, 2,3,4,5,6-pentabromo- 13C6) is the 13C-labeled 1,2,3,4,5-Pentabromo-6-methylbenzene (HY-W274110).
|
-
- HY-W699983
-
|
Glyoxaline-15N<SUB>2SUB>; 1,3-Diaza-2,4-cyclopentadiene-15N<SUB>2SUB>
|
Isotope-Labeled Compounds
Thrombopoietin Receptor
Ser/Thr Protease
Xanthine Oxidase
|
Neurological Disease
Inflammation/Immunology
|
|
Imidazole- 15N2 (Glyoxaline- 15N2) is 15N labeled Imidazole. Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG2 and PGH2) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CL Pro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease [1] .
|
-
- HY-W040193S3
-
|
1,2-Distearoyl-sn-glycero-3-PC-d<SUB>83SUB>; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d<SUB>83SUB>
|
Isotope-Labeled Compounds
Liposome
|
Others
|
|
DSPC-d83 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d83) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system [1] .
|
-
- HY-113123S1
-
|
14:0 Lyso PC-d<SUB>7SUB>; 1-myristoyl-sn-glycero-3-phosphatidylcholine-d<SUB>7SUB>
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Neurological Disease
Metabolic Disease
|
|
LysoPC(14:0/0:0)-d7 (14:0 Lyso PC-d7) is deuterium labeled LysoPC(14:0/0:0). LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect [1] .
|
-
- HY-146894S
-
|
1,2-Distearoyl-sn-glycero-3-PC-d<SUB>35SUB>; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d<SUB>35SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Stearoyl-2-stearoyl-sn-glycero-3-phosphocholine-d35 is deuterium labeled 1-Stearoyl-2-stearoyl-sn-glycero-3-phosphocholine.
|
-
- HY-W040193S5
-
|
1,2-Distearoyl-sn-glycero-3-PC-d<SUB>9SUB>; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d<SUB>9SUB>
|
Isotope-Labeled Compounds
Liposome
|
Others
|
|
DSPC-d9 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d9) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system [1] .
|
-
- HY-Y1772S
-
|
p-Iodotoluene-d<SUB>7SUB>; p-Methyliodobenzene-d<SUB>7SUB>; p-Tolyl iodide-d<SUB>7SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Iodo-4-methylbenzene-d7 is the deuterium labeled 1-Iodo-4-methylbenzene [1].
|
-
- HY-W285163S
-
|
Formyl Ciprofloxacin-d<SUB>8SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Cyclopropyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid-d8 is deuterated labeled 1-Cyclopropyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid.
|
-
- HY-134178S1
-
|
5-Fluorouridine 5'-triphosphate-13C,19F,d<SUB>1SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
5-F-UTP- 13C, 19F,d1 is deuterium and 13C-labeled 5-F-UTP (HY-134178).
|
-
- HY-12650S
-
|
DS5565-13C<SUB>2SUB>,d<SUB>1SUB> (Mixture of Diastereomers)
|
Isotope-Labeled Compounds
|
Others
|
|
Mirogabalin- 13C2,d1 (Mixture of Diastereomers) is a 13C and deuterium labeled Mirogabalin. Mirogabalin (DS-5565) is a preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS [1].
|
-
- HY-W040193S4
-
|
1,2-Distearoyl-sn-glycero-3-PC-d<SUB>4SUB>; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d<SUB>4SUB>
|
Isotope-Labeled Compounds
Liposome
|
Others
|
|
DSPC-d4 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d4) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system [1] .
|
-
- HY-Y0860S
-
|
1,6-Dibromohexane-d<SUB>12SUB>; Hexamethylene dibromide-d<SUB>12SUB>; NSC 7306-d<SUB>12SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,6-Dibromo-n-hexane-d12 is the deuterium labeled 1,6-Dibromo-n-hexane [1].
|
-
- HY-146881S
-
|
DMPC-d<SUB>27SUB>; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d<SUB>27SUB>; Dimyristoyl phosphatidylcholine-d<SUB>27SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Myristoyl-2-myristoyl-sn-glycero-3-phosphocholine-d27 is deuterium labeled 1-Myristoyl-2-myristoyl-sn-glycero-3-phosphocholine.
|
-
- HY-122056S1
-
|
L-α-Diheptanoyllecithin-d<SUB>26SUB>; 12-Diheptanoyl-sn-glycero-3-PC-d<SUB>26SUB>
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
1,2-Diheptanoyl-SN-glycero-3-phosphocholine-d26 (L-α-Diheptanoyllecithin-d26) is the deuterium labeled 1,2-Diheptanoyl-SN-glycero-3-phosphocholine (HY-122056). 1,2-Diheptanoyl-SN-glycero-3-phosphocholine (L-α-Diheptanoyllecithin; 12-Diheptanoyl-sn-glycero-3-PC) is an ester product.
|
-
- HY-W583868S
-
|
1,2-POPE-d<SUB>62SUB>; 16:0-18:1 PE-d<SUB>62SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Palmitoyl-2-oleoyl-sn-glycero-3-PE-d62 (1,2-POPE-d62) is the deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE (1,2-POPE; 16:0-18:1 PE) is a phosphatidylethanolamine (PE) lipid. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can induce lipid bilayer to form a hexagonal phase (HII) structure in an acidic environment and promote membrane fusion. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can enhance the endosomal escape ability of lipid nanoparticles (LNPs) and improve the cellular delivery efficiency of nucleic acid drugs such as mRNA. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can be used for LNP carrier targeting of gene therapy and mRNA vaccines [1] .
|
-
- HY-178703S
-
|
L-α-Diheptanoyllecithin-d<SUB>9SUB>; 12-Diheptanoyl-sn-glycero-3-PC-d<SUB>9SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,2-Diheptanoyl-SN-glycero-3-phosphocholine-d9 (L-α-Diheptanoyllecithin-d9) is the deuterium labeled 1,2-Diheptanoyl-SN-glycero-3-phosphocholine.
|
-
- HY-Y0659S
-
|
1,2,3,4-Tetrahydroquinoline-d<SUB>2SUB>; 3,4-Dihydro-2H-quinoline-d<SUB>2SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,2,3,4-Hydroquinoline-d2 (1,2,3,4-Tetrahydroquinoline-d2) is the deuterium labeled 1,2,3,4-Hydroquinoline.
|
-
- HY-122056S
-
|
L-α-Diheptanoyllecithin-d<SUB>35SUB>; 12-Diheptanoyl-sn-glycero-3-PC-d<SUB>35SUB>
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
1,2-Diheptanoyl-SN-glycero-3-phosphocholine-d35 (L-α-Diheptanoyllecithin-d35) is the deuterium labeled 1,2-Diheptanoyl-SN-glycero-3-phosphocholine (HY-122056). 1,2-Diheptanoyl-SN-glycero-3-phosphocholine (L-α-Diheptanoyllecithin; 12-Diheptanoyl-sn-glycero-3-PC) is an ester product.
|
-
- HY-W013053S
-
|
DBA-d<SUB>14SUB>; 1,2,5,6-Dibenzanthracene-d<SUB>14SUB>; Benzo[k]tetraphene-d<SUB>14SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
Dibenz[a,h]anthracene-d14 is the deuterium Dibenz[a,h]anthracene.
|
-
![Dibenz[a,h]anthracene-d14](//file.medchemexpress.com/product_pic/hy-w013053s.gif)
- HY-W762019S
-
|
1,2,3,4,7,8-HxCDD-13C<SUB>12SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,2,3,4,7,8-Hexachloro dibenzo-p-dioxin- 13C12 (1,2,3,4,7,8-HxCDD- 13C12) is 13C labeled 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin [1].
|
-
- HY-W662572S
-
|
N-(5,7-Dimethoxy-d<SUB>6SUB>[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide
|
Isotope-Labeled Compounds
|
Others
|
|
Pyroxsulam-d6 (N-(5,7-Dimethoxy-d6[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide) is deuterium labeled N-(5,7-Dimethoxy-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide [1].
|
-
- HY-41681S
-
|
1-Chloro-6-hexanol-d<SUB>6SUB>; 1-Chloro-6-hydroxyhexane-d<SUB>6SUB>; 6-Chlorohexanol-d<SUB>6SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
6-Chloro-1-hexanol-d6 is the deuterium labeled 6-Chloro-1-hexanol [1].
|
-
- HY-W050145S2
-
|
1,6-Anhydro-β-D-glucopyranose-13C<SUB>6SUB>; 1,6-Anhydro-β-D-glucose-13C<SUB>6SUB>
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Levoglucosan- 13C6 is the 13C labeled Levoglucosan [1]. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature .
|
-
- HY-151997S
-
|
1,2-Olein-3-laurin-13C3; TG(18:1/18:1/12:0)-13C<SUB>3SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,2-Dioleoyl-3-lauroyl-rac-glycerol- 13C3 is the 13C-labeled 1,2-Dioleoyl-3-lauroyl-rac-glycerol (HY-165089), 1,2-Dioleoyl-3-lauroyl-rac-glycerol (1,2-Olein-3-laurin) is a triglyceride identified by specific analytical methods in human milk, infant formula, other mammalian milk, and vegetable oils, with specific structural and distribution characteristics.
|
-
- HY-141919S
-
|
4-Iodobromobenzene-13C<SUB>6SUB>; 4-Iodophenyl bromide-13C<SUB>6SUB>; NSC 8033-13C<SUB>6SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Bromo-4-iodobenzene- 13C6 is the 13C labeled 1-Bromo-4-iodobenzene [1].
|
-
- HY-115705S
-
|
Glycerol tri-10(Z)-heptadecenoate-d<SUB>5SUB>; TG(17:1/17:1/17:1)-d<SUB>5SUB>; Tri-10(Z)-heptadecenoin-d<SUB>5SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1,2,3-Tri-10(Z)-Heptadecenoyl Glycerol-d5 is the deuterium labeled 1,2,3-Tri-10(Z)-Heptadecenoyl Glycerol [1].
|
-
- HY-W766078
-
|
1-b-D-Arabinofuranosyluracil-13C,15N<SUB>2SUB>; Uracil 1-β-D-arabinofuranoside-13C,15N<SUB>2SUB>
|
Isotope-Labeled Compounds
|
Infection
Cardiovascular Disease
Cancer
|
|
1-beta-D-Arabinofuranosyluracil- 13C, 15N2 (1-b-D-Arabinofuranosyluracil- 13C, 15N2; Uracil 1-β-D-arabinofuranoside- 13C, 15N2) is the 13C- and 15N-labeled labeled 1-beta-D-Arabinofuranosyluracil (HY-N6652). 1-beta-D-Arabinofuranosyluracil (Uracil 1-β-D-arabinofuranoside) isolated from the Caribbean sponge Tectitethya crypta, is a methoxyadenosine derivative. 1-beta-D-Arabinofuranosyluracil has demonstrated a diverse bioactivity profile including anti-inflammatory activity, analgesic and vasodilation properties [1]. 1-beta-D-Arabinofuranosyluracil reduces a proliferation of mouse lymphoma cells .
|
-
- HY-Y0219S
-
|
s-Triazole13C<SUB>2SUB>,15N<SUB>3SUB>; Pyrrodiazole13C<SUB>2SUB>,15N<SUB>3SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
NSC 83128- 13C2, 15N3 is the 13C and 15N labeled NSC 83128 [1].
|
-
- HY-A0052S
-
|
Telaprevir, (R)-d<SUB>4SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
(1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1R)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide-d4 is deuterated labeled (1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1R)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide.
|
-
![(1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1R)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide-d4](//file.medchemexpress.com/product_pic/hy-a0052s.gif)
- HY-Y0045S
-
|
1-(1,3-Thiazol-2-yl)ethanone-13C<SUB>2SUB>; 1-(Thiazol-2-yl)ethanone-13C<SUB>2SUB>; Methyl 2-thiazolyl ketone-13C<SUB>2SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
2-Acetylthiazole- 13C2 is 13C labeled 2-Acetylthiazole (HY-Y0045). 2-Acetylthiazole (1-(1,3-Thiazol-2-yl)ethanone; 1-(Thiazol-2-yl)ethanone; Methyl 2-thiazolyl ketone) is a flavor compound. 2-Acetylthiazole is a kind of biological materials or organic compounds that are widely used in life science research [1].
|
-
- HY-33948S
-
|
1,1-Dimethylethanolamine-d<SUB>6SUB>; 2-Amino-α,α-dimethylethanol-d<SUB>6SUB>; 2-Hydroxy-2-methyl-1-propylamine-d<SUB>6SUB>; 2-Hydroxy-2-methylpropan-1-amine-d<SUB>6SUB>
|
Isotope-Labeled Compounds
|
Others
|
|
1-Amino-2-methylpropan-2-ol-d6 is the deuterium labeled 1-Amino-2-methylpropan-2-ol [1].
|
-
- HY-59354S1
-
|
1,2-Dihydro-3,6-pyridazine-13C<SUB>4SUB>-dione; 3,6-Dihydroxypyridazine-13C<SUB>4SUB>; 3,6-Pyridazine-13C<SUB>4SUB>-diol; Maleic hydrazide-13C<SUB>4SUB>
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
|
Cancer
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1,2-Dihydropyridazine-3,6-dione-3,4,5,6- 13C4 (1,2-Dihydro-3,6-pyridazine- 13C4-dione) is 13C labeled Maleic hydrazide. Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins [1] .
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-
- HY-34123S
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2-(2-Bromoethyl)-1H-isoindole-1,3(2H)-dione-d<SUB>4SUB>; 1-Bromo-2-phthalimidoethane-d<SUB>4SUB>; 2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethyl bromide-d<SUB>4SUB>; 2-(2-Bromoethyl)-2,3-dihydro-1H-isoindole-1,3-dione
|
Isotope-Labeled Compounds
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Others
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N-(2-Bromoethyl)phthalimide-d4 is the deuterium labeled N-(2-Bromoethyl)phthalimide[1].
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-
- HY-W778954
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(2,2-Dimethyl-[1,3] dioxane-4-yl)-methanol-13C<SUB>3SUB>; (4RS)-2,2-Dimethyl-1,3-dioxolane-4-methanol-13C<SUB>3SUB>; (RS)-Solketal-13C<SUB>3SUB>; (±)-1,2-O-Isopropylideneglycerol-13C<SUB>3SUB>; (±)-2,2-Dimethyl-1,3-dioxolane-4-methanol-13C<SUB>3SUB>; (±)-Glycerol 1,2-acetonide-13C<SUB>3SUB>; Solketa-13C<SUB>3SUB>l
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Isotope-Labeled Compounds
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Others
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2,2-Dimethyl-1,3-dioxolane-4-methanol- 13C3 ((2,2-Dimethyl-[1,3] dioxane-4-yl)-methanol- 13C3) is the 13C-labeled 2,2-Dimethyl-1,3-dioxolane-4-methanol (HY-Y1372).
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| Cat. No. |
Product Name |
Type |
-
- HY-109541S1
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DMPC-d<SUB>4SUB>; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d<SUB>4SUB>
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Biochemical Assay Reagents
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Colfosceril miristate-d4 (DMPC-d4) is deuterium labeled Colfosceril miristate. Colfosceril miristate is a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery [1] .
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- HY-109541S5
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DMPC-d<SUB>67SUB>; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d<SUB>67SUB>
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Biochemical Assay Reagents
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1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d67 is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine
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- HY-109541S2
-
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DMPC-d<SUB>9SUB>; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d<SUB>9SUB>
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Biochemical Assay Reagents
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Colfosceril miristate-d9 (DMPC-d9) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery [1] .
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-
- HY-109541S
-
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DMPC-d<SUB>58SUB>; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d<SUB>58SUB>
|
Biochemical Assay Reagents
|
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Colfosceril miristate-d58 (DMPC-d58) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery [1] .
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-
- HY-109541S4
-
|
DMPC-d<SUB>63SUB>; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d<SUB>63SUB>
|
Biochemical Assay Reagents
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Colfosceril miristate-d63 (DMPC-d63) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery [1] .
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-
- HY-109541S3
-
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DMPC-d<SUB>13SUB>; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d<SUB>13SUB>
|
Biochemical Assay Reagents
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Colfosceril miristate-d13 (DMPC-d13) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery [1] .
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| Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P10215
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Parasite
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Infection
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Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent Plasmodium subtilisin-like protease 1 (SUB1) inhibitor. SUB1-IN-1 shows IC50 values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively [1].
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* This product has been "discontinued".
Optimized version of product available:
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| Cat. No. |
Product Name |
Chemical Structure |
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- HY-B0892S4
-
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Benzyl alcohol-d1 is the deuterium labeled Benzyl alcohol [1].
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-
-
- HY-13966S
-
1 Publications Verification
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2-Deoxy-D-glucose-d is the deuterium labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase [1] .
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-
-
- HY-90006S
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5-Fluorouracil-d is the deuterium labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer [1] . 5-Fluorouracil also inhibits HIV .
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-
- HY-B0389S1
-
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D-Glucose-d is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molec
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-
-
- HY-B0152S
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Adenine-d is the deuterium labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis [1] .
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-
-
- HY-N7092S11
-
|
|
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D-Fructose-d-1 is the deuterium labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants [1].
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-
-
- HY-B0389S2
-
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D-Glucose-d12-12 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response [1].
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-
-
- HY-B0389S8
-
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|
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D-Glucose-d-44 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response [1].
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-
-
- HY-B0511S
-
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|
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Biotin-d2-1 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.
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-
-
- HY-14648S5
-
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Dexamethasone-d3-1 (Hexadecadrol-d3-1; Prednisolone F-d3-1) is a deuterium labeled Dexamethasone (HY-14648). Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.
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-
-
- HY-10585S4
-
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Valproic acid-d4-1 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches [1] .
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-
-
- HY-12215S2
-
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|
|
Deulorlatinib (compound A), a deuterated derivative of Lorlatinib (HY-12215), is a potent inhibitor of tyrosine kinase demonstrating the potential for the research of ALK-positive advanced NSCLC [1] .
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-
-
- HY-W004263S
-
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|
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1-Eicosanol-d41 (Arachidyl alcohol-d41) is the deuterium labeled 1-Eicosanol (HY-W004263) [1]. 1-Eicosanol is a natural compound with antioxidant activity found in Justicia insularis leaves. 1-Eicosanol can be used as an antioxidant .
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-
-
- HY-W016577S4
-
|
|
|
1-Bromoheptane-d1 is the deuterium labeled 1-Bromoheptane [1].
|
-
-
- HY-B0389S4
-
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|
|
D-Glucose-d1-2 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response [1].
|
-
-
- HY-B1411S1
-
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|
|
i-Inositol-d is the deuterium labeled i-Inositol [1].
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-
-
- HY-10162S3
-
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|
|
Olaparib-d4-1 (AZD2281-d4-1) is the deuterium labeled Olaparib (HY-10162). Olaparib is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator [1] .
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-
-
- HY-70057S1
-
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|
|
Safinamide-d4-1 is deuterium labeled Safinamide. Safinamide is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 μM) over MAO-A (IC50=580 μM) [1]. Safinamide also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC50=8?μM) than at resting (IC50=262?μM) potentials. Safinamide has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke etc.al .
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-
-
- HY-100442S1
-
|
|
|
Paquinimod-d5-1 is a deuterated analog of Paquinimod (HY-100442). Paquinimod (ABR 215757) is a specific and orally active inhibitor of S100A8/S100A9. Paquinimod rescues the pneumonia with substantial reduction of viral loads in SARS-CoV-2-infected mice [1] .
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-
-
- HY-B1659S3
-
|
|
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Glycerol-d is the deuterium labeled Glycerol. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis.
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-
-
- HY-W032013S1
-
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|
|
1-Octanol-d2 is the deuterium labeled 1-Octanol [1]. 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents . 1-Octanol is a highly attractive biofuel with diesel-like properties .
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-
-
- HY-A0070AS2
-
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|
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Liothyronine- 13C6-1 is a 13C-labeled Liothyronine. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively [1] .
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-
-
- HY-W004292S
-
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|
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1-Undecanol-d23 (Undecyl alcohol-d23) is the deuterium labeled 1-Undecanol (HY-W004292). 1-Undecanol (Undecyl alcohol) is the main product generated from the degradation of 2-tridecanone by Pseudomonas bacteria isolated from the soil. 1-Undecanol can enhance the attraction of Grapholita molesta to sex pheromone traps [1] .
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-
-
- HY-N0210S6
-
|
|
|
D-Galactose-d-1 is the deuterium labeled D-Galactose. D-Galactose is a natural aldohexose and C-4 epimer of glucose.
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-
-
- HY-109037S2
-
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|
|
Mavacamten-d1 (MYK461-d1; SAR439152-d1) is deuterium labeled Mavacamten (HY-109037). Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively.
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-
-
- HY-N0488S1
-
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|
|
Vincristine-d3 sulfate is the deuterium labeled Vincristine sulfate. Vincristine-1 sulfate (Leurocristine; NSC-67574; 22-Oxovincaleukoblastine) is a microtubule inhibitor that disrupts microtubule polymerization by binding to β-tubulin (with a Ki of 85 nM in bovine), arrests the cell cycle and induces apoptosis. Vincristine-1 sulfate inhibits cell replication, tumor blood flow and the proliferation of various cancer cells, while triggering effects such as oxidative stress, inflammation, calcium overload, epithelial-mesenchymal transition and peripheral neuropathic pain. Vincristine-1 sulfate upregulates the expression of various transporters and nuclear receptors, and enriches gastric cancer stem-like cells. Vincristine-1 sulfate is used in research related to various tumors including acute lymphoblastic leukemia, lymphoma, melanoma, gastric cancer, solid tumors and sarcomas [1] .
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-
-
- HY-14648S1
-
|
|
|
Dexamethasone-d5-1 is deuterium labeled Dexamethasone. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.
|
-
-
- HY-108506S2
-
|
|
|
Licarbazepine-d4-1 is deuterium labeled Licarbazepine. Licarbazepine (BIA 2-005; GP 47779)?is a?voltage-gated sodium channel?blocker?with?anticonvulsant?and?mood-stabilizing?effects [1].
|
-
-
- HY-W778692
-
|
|
|
1-Linoleoyl Glycerol-d5 (1-Linoleoyl-rac-glycerol-d5; 1-Monolinolein-d5) is the deuterium labeled 1-Linoleoyl Glycerol (HY-111346). 1-Linoleoyl glycerol is a LpPLA2 inhibitor. 1-Linoleoyl glycerol acts as a precursor for synthesizing various functional lipids, such as phospholipids. 1-Linoleoyl glycerol mitigates inflammation induced by Apolipoprotein CIII (reduction of IL-6) [1] .
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-
-
- HY-13331S2
-
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|
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Clascoterone-d5-1 (Cortexolone 17 alpha-propionate-d5-1) is deuterium labeled Clascoterone. Clascoterone (Cortexolone 17 alpha-propionate;Cortexolone 17α-propionate;CB-03-01) is a new topical and peripherally selective androgen antagonist [1].
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-
-
- HY-Y0308S
-
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|
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Phosphate dibasic-d2 (sodium) is the deuterium labeled Sodium phosphate dibasic [1].
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-
-
- HY-18341S4
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L-Thyroxine- 13C6-1 (Levothyroxine- 13C6-1; T4- 13C6-1) is a 13C labeled L-Thyroxine (HY-18341). L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) [1] .
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-
-
- HY-W004293S
-
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|
|
n-Tridecyl Alcohol-d27 is the deuterium labeled 1-Tridecanol [1].
|
-
-
- HY-W110702S1
-
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|
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1-Bromotridecane-d4 is the deuterium labeled 1-Bromotridecane [1].
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-
-
- HY-W111467S
-
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|
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1-Bromoeicosane-d41 is the deuterium labeled 1-Bromoicosane [1].
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-
-
- HY-41700S2
-
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D-Alanine-d is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR [1].
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-
-
- HY-N0378S5
-
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D-Mannitol-d is the deuterium labeled D-Mannitol (HY-N0378). D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells [1] . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .
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-
-
- HY-B0389S7
-
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D-Glucose-d-33 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response [1].
|
-
-
- HY-19696S2
-
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|
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Tauroursodeoxycholate-d4-1 is the deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.
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-
-
- HY-B0141S6
-
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Estradiol-d2-1 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway [1] .
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-
-
- HY-B0763S2
-
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Ibudilast-d7-1 is the deuterium labeled Ibudilast [1]. Ibudilast (KC-404;AV-411;MN-166) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia .
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-
-
- HY-B0228S7
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Adenosine-d-1 is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular phys
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-
-
- HY-B0479S1
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Thiamphenicol-d3-1 (Thiophenicol-d3-1; Dextrosulphenidol-d3-1) is the deuterium-labeled Thiamphenicol (HY-B0479) [1]. Thiamphenicol (Thiophenicol)，a methyl-sulfonyl derivative of Chloramphenicol，is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit，leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative，Gram-positive aerobic and anaerobic bacteria) .
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-
-
- HY-12222S1
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Obeticholic Acid-d4 is the deuterium labeled Obeticholic acid. Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy [1] .
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-
-
- HY-14649S6
-
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Retinoic acid-d3-1 is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha [1] .
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-
-
- HY-B0234S4
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Estrone-d2-1 is the deuterium labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells [1] .
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-
-
- HY-17043S2
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Loratadine-d4-1 (Loratidine-d4-1) is deuterium labeled Loratadine. Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory mediators [1].
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-
- HY-23188
-
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Loratadine-d5-1 is a deuterated labeled Loratadine (HY-17043). Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory mediators.
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-
-
- HY-50898S3
-
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|
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Lapatinib-d4-1 is deuterium labeled Lapatinib. Lapatinib (GW572016) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively [1].
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-
-
- HY-B0400S7
-
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D-Sorbitol-d-2 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and di
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-
- HY-G0016S1
-
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N-acetyl Dapsone-d4-1 is the deuterium labeled N-acetyl Dapsone, which is a metabolite of Dapsone.
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-
- HY-B0400S8
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D-Sorbitol-d2-1 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and di
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- HY-13593S1
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Chlorambucil-d8-1 is the deuterium labeled Chlorambucil. Chlorambucil (CB-1348), an orally active antineoplastic agent, is a bifunctional alkylating agent belonging to the nitrogen mustard group. Chlorambucil can be used for the research of lymphocytic leukemia, ovarian and breast carcinomas, and Hodgkin’s disease [1] .
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- HY-B0801S4
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Fexofenadine-d3-1 fumarate is deuterated labeled Fexofenadine (HY-B0801). Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research [1] .
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- HY-A0095S1
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Flibanserin-d4-1 is deuterium labeled Flibanserin. Flibanserin (BIMT-17) is a full agonist of the serotonin 5-HT1A receptor (Ki=1 nM) and an antagonist of 5-HT2A (49 nM). Flibanserin binds to dopamine D4 receptors (4-24 nM), and has negligible affinity for a variety of other neurotransmitter receptors and ion channels. Flibanserin is efficacious in treating hypoactive sexual desire disorder (HSDD) [1] .
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- HY-15592S2
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Cabotegravir d3-1 (GSK-1265744-d3-1) is a deuterium substitute of Cabotegravir. Cabotegravir is a potent HIV integrase inhibitor used in AIDS research [1]
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- HY-B1716S1
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L-5-Hydroxytryptophan-d3-1 is the deuterium labeled L-5-Hydroxytryptophan [1]. L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist . L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia .
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- HY-B0389S18
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D-Glucose- 13C3-1 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response [1].
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- HY-B0389S25
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D-Glucose- 13C,d is the deuterium and 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical sig
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- HY-B0158S4
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Cytidine-d is the deuterium labeled Cytidine. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catechol
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- HY-141636S
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1-PalMitoyl-2-arachidoyllecithin-d9-1 (1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine-d9-1) is deuterium labeled 1-PalMitoyl-2-arachidoyllecithin. 1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PC (PAPC) is a phospholipid containing palmitic acid (16:0) and arachidonic acid (20:4) at the sn-1 and sn-2 positions, respectively, that is found in biological membranes. PAPC is oxidized in vivo, and its oxidation products are involved in chronic inflammation and vascular disease. PAPC has been used to study signaling of oxidized phospholipids. Levels of PAPC are decreased in isolated human multiple myeloma cells [1].
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- HY-W032013S
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1-Octanol-d17 is the deuterium labeled 1-Octanol [1]. 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents . 1-Octanol is a highly attractive biofuel with diesel-like properties .
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- HY-W032013S3
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1-Octanol-d5 is deuterated labeled 1-Octanol (HY-W032013). 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents [1]. 1-Octanol is a highly attractive biofuel with diesel-like properties .
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- HY-B0158S3
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Cytidine-d2-1 is the deuterium labeled Cytidine. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catech
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- HY-W720915
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N-Dodecylbenzene-d5 (1-Dodecylbenzene-d5; 1-Phenyl-n-dodecane-d5; 1-Phenyldodecane-d5) is the deuterium labeled N-Dodecylbenzene (HY-Y1052).
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- HY-66008S1
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N-Acetyl mesalazine-d3-1 (N-Acetyl-5-aminosalicylic acid-d3-1) is deuterium labeled N-Acetyl mesalazine (HY-66008). N-Acetyl mesalazine (N-Acetyl-5-aminosalicylic acid) is the primary intestinal metabolite of 5-Aminosalicylic Acid (HY-15027) and serves as a biomarker for evaluating the efficacy of 5-Aminosalicylic Acid (HY-15027). N-Acetyl mesalazine can scavenge free radicals, reduce DNA base hydroxylation, and ameliorate mucosal inflammation. N-Acetyl mesalazine can be used in the study of diseases such as colitis and colon cancer [1].
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- HY-A0042S2
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Rufinamide- 15N,d2-1 (CGP 33101- 15N,d2-1) is 15N- and deuterium-labeled Rufinamide (HY-A0042).Rufinamide (CGP 33101) is an orally active antiepileptic compound that inhibits Na + current activation, inhibits neuronal hyperexcitability, and has anticonvulsant effects. Rufinamide is used in the study of Lennox-Gastaut syndrome [1] .
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- HY-B0122SS1
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Topiramate- 13C6-1 (McN 4853- 13C6-1; RWJ 17021- 13C6-1) is 13C-labeled Topiramate (HY-B0122) [1].
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- HY-N0717S8
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L-Valine-d1 ((S)-Valine-d1) is the deuterium labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase [1] .
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- HY-N0131S1
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Stigmasterol-d5-1 is deuterium labeled Stigmasterol. Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases [1].
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- HY-W004292S1
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1-Undecanol-d4 (Undecyl alcohol-d4) is the deuterium labeled 1-Undecanol (HY-W004292). 1-Undecanol (Undecyl alcohol) is the main product generated from the degradation of 2-tridecanone by Pseudomonas bacteria isolated from the soil. 1-Undecanol can enhance the attraction of Grapholita molesta to sex pheromone traps [1] .
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- HY-152070S1
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Demethylmaprotiline-d2-1 is the deuterium labeled Demethylmaprotiline [1].
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- HY-135810S1
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Cletoquine-d4-1 is the deuterium labeled Cletoquine. Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune diseases treatment [1] .
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- HY-B0412S4
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Estriol-d3-1 is the deuterium labeled Estriol.
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- HY-B0111S1
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Drospirenone-d4-1 is deuterium labeled Drospirenone.
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- HY-Y1004S3
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1-Decanol-d5 is the deuterium labeled 1-Decanol [1].
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- HY-B0389S3
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D-Glucose-d-11 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response [1].
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- HY-W099504S2
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1-Heptanol-d1 is the deuterium labeled 1-Heptanol [1].
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- HY-B0389S23
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D-Glucose-d2-1 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling mol
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- HY-109025AS2
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Baloxavir-d1 is the deuterium labeled Baloxavir (HY-109025A). Baloxavir (Baloxavir acid), derived from the proagent Baloxavir marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir inhibits viral RNA transcription and replication and has potently antiviral activity [1] .
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- HY-Y0001S1
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Cyclopropane-1-carboxylic Acid-d1 is the deuterium labeled Cyclopropane-1-carboxylic Acid [1].
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- HY-W051547S2
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1-(2-Chloropyridin-3-yl)ethanol-d1 (2-Chloro-3-(1-hydroxyethyl)pyridine-d1) is the deuterium labeled 1-(2-Chloropyridin-3-yl)ethanol.
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- HY-W752893
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D-4-Hydroxyphenylglycine-d5-1 (D-(-)-4-Hydroxyphenylglycine-d5-1) is the deuterium labeled D-4-Hydroxyphenylglycine (HY-34588). D-4-Hydroxyphenylglycine (D-(-)-4-Hydroxyphenylglycine) is one of the most important raw materials used in the production of semisynthetic β-lactam antibiotics, such as Amoxicillin (HY-B0467A) and Cefadroxil (HY-B1190) [1].
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- HY-W087024S
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1-Phenylpentane-d5 is the deuterium labeled 1-Phenylpentane [1].
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- HY-14444S
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Plinabulin-d1 is an active compound.
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- HY-145547S
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1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine-d27 (14:0 Lyso PE-d27) is the deuterium labeled 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine. 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells [1].
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- HY-178736S
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1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine-d46 (DLPE-d46) is the deuterium labeled 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine.
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- HY-34705S
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- HY-Y1004S4
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1-Decanol-d4 is the deuterium labeled 1-Decanol [1].
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- HY-W014559S4
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1-Bromononane-d5 (Nonyl bromide-d5) is the deuterium labeled 1-Bromononane.
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- HY-Y1809S
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1-Hydroxyoctadecane-d37 is the deuterium labeled 1-Hydroxyoctadecane [1]. 1-Hydroxyoctadecane is an endogenous metabolite.
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- HY-122426S1
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1-Bromoundecane-d3 is the deuterium labeled 1-Bromoundecane [1].
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- HY-124891S
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1-Phenylpyrrole-d9 (N-Phenylpyrrole-d9) is the deuterium labeled 1-Phenylpyrrole (HY-124891). 1-Phenylpyrrole (N-Phenylpyrrole) has dual fluorescent properties. 1-Phenylpyrrole displays a single band in nonpolar solvents and a second red-shifted fluorescent band in polar solvents [1].
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- HY-W723937
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1-Bromopentadecane-d4 (Pentadecyl bromide-d4) is the deuterium labeled 1-Bromopentadecane.
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- HY-W009141S
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1-Monopalmitin-d31 (Glyceryl palmitate-d31) is the deuterium labeled 1-Monopalmitin (HY-W009141). 1-Monopalmitin (Glyceryl palmitate) is an activator of the PI3K/Akt pathway and an inhibitor of P-glycoprotein (P-gp). 1-Monopalmitin can induce G2/M arrest and caspase-dependent apoptosis in cancer cells, while inhibiting IAPs protein expression. 1-Monopalmitin can increase drug accumulation by inhibiting P-gp activity in intestinal Caco-2 cells. 1-Monopalmitin has the ability to induce protective autophagy and apoptosis of lung cancer cells (IC50=50-58 μg/mL), with low toxicity to normal cells [1] .
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- HY-Y1004S1
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1-Decanol-d2 is a deuterated 1-Decanol. 1-Decanol is used in the production of lubricants,?surfactants, plasticizers and?solvents. It has also been used to study the thermal properties of polymeric monolithic stationary phases and to enhance homopolyglycine acceptor function. Used in cosmetics, daily flavors, and food flavors.
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- HY-N0210S5
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D-Galactose-d is the deuterium labeled D-Galactose. D-Galactose is a natural aldohexose and C-4 epimer of glucose.
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- HY-W724384
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1-Bromotridecane-d9 (Tridecyl Bromide-d9) is the deuterium labeled 1-Bromotridecane.
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- HY-Y1004S
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1-Decanol-d3 is a deuterated 1-Decanol. 1-Decanol is used in the production of lubricants,?surfactants, plasticizers and?solvents. It has also been used to study the thermal properties of polymeric monolithic stationary phases and to enhance homopolyglycine acceptor function. Used in cosmetics, daily flavors, and food flavors.
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- HY-W111468S
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1-Iodohexadecane-d4 (Hexadecyl Iodide-d4) is the deuterium labeled 1-Iodohexadecane.
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- HY-Y1809S1
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1-Hydroxyoctadecane-d2 is the deuterium labeled 1-Hydroxyoctadecane [1]. 1-Hydroxyoctadecane is an endogenous metabolite.
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- HY-Y1139S
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Pimelic acid-d4 is the deuterium labeled Pimelic acid [1]. Pimelic acid is the organic compound and its derivatives are involved in the biosynthesis of the amino acid called lysine.
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- HY-Y0921S1
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(±)-1,2-Propanediol-d2 is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents [1] .
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- HY-Y0921S
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(±)-1,2-Propanediol-d8 is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents [1] .
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- HY-Y0921S2
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(±)-1,2-Propanediol-d6 is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents [1] .
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- HY-W765245
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Rapamycin- 13C,d3-1 (Sirolimus- 13C,d3-1) is the deuterium labeled and 13C-labeled Rapamycin (HY-10219). Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1 [1]. Rapamycin is an autophagy activator, an immunosuppressant .
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- HY-113136S
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1-Methylguanosine-d3 (N1-Methylguanosine-d3) is deuterium labeled 1-Methylguanosine (HY-113136). 1-Methylguanosine is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker [1] .
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- HY-B0901S1
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Bromperidol-d4-1 is deuterium labeled Bromperidol.
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- HY-153939S
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Idasanutlin-d3-1 (RG7388-d3-1) is the deuterium labeled Idasanutlin. Idasanutlin is a potent antagonist of MDM2/p53. Idasanutlin inhibits relapsed or refractory acute myeloid leukemia [1] .
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- HY-19822S1
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Elacestrant-d4-1 is the deuterium labeled Elacestrant (HY-19822). Elacestrant is an orally available and selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively [1] .
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- HY-W032015S3
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1-Bromooctane-d4 is the deuterium labeled 1-Bromooctane [1].
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- HY-B0114S1
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Oxcarbazepine-d4-1 is deuterium labeled Oxcarbazepine. Oxcarbazepine is a sodium channel blocker [1]. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines . Anti-cancer and anticonvulsant effects .
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- HY-W752616
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1-Aminopropan-2-ol-d6 (Monoisopropanolamine-d6) is the deuterium labeled 1-Aminopropan-2-ol (HY-W015969). 1-Aminopropan-2-ol is a microbial metabolism of amino alcohol metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas [1].
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- HY-W089832S
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1,1-Dimethylurea-d6 is the deuterium labeled 1,1-Dimethylurea [1].
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- HY-12987S2
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Pimozide-d4-1 is the deuterium labeled Pimozide. Pimozide is a dopamine receptor antagonist, with Kis of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor, with a Ki of 39 nM; Pimozide also inhibits STAT3 and STAT5 [1] .
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- HY-W711089
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Bifenox-d3-1 (Modown-d3; MC-4379-d3) is the deuterium labeled Bifenox (HY-136513). Bifenox (Modown; MC-4379) is a potent herbicide. Bifenox increases the ROS production. Bifenox causes cellular membrane disruption, inhibition of photosynthesis [1].
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- HY-W099504S
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n-Heptyl Alcohol-d15 is the deuterium labeled 1-Heptanol [1].
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- HY-B0113S1
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Omeprazole-d3-1 is the deuterium labeled Omeprazole. Omeprazole-1 (H 16868) is an orally active H +,K +-ATPase inhibitor and a proton pump inhibitor. Omeprazole-1 competitively inhibits CYP2C19, CYP3A4, and CYP2C9 activity. Omeprazole-1 inhibits gastric acid secretion and can be used for acid-related gastrointestinal disorders. Omeprazole-1 inhibits pancreatic cancer cell proliferation, induces apoptosis, autophagosome accumulation (elevated LC3-I and LC3-II levels), oxidative stress, and cytogenetic imbalance, modulates lysosomal transport, reduces inflammatory cytokines. Omeprazole-1 alters small intestinal morphology and magnesium absorption, and induces gastric mucosa morphologic changes. Omeprazole-1 aslo has neuroprotective and antibacterial effects [1] .
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- HY-B0561S2
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Spironolactone-d3-1 is deuterium labeled Spironolactone. Spironolactone (SC9420) is an orally active aldosterone mineralocorticoid receptor antagonist with an IC50 of 24 nM. Spironolactone is also a potent antagonist of androgen receptor with an IC50 of 77 nM. Spironolactone promotes autophagy in podocytes [1] .
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- HY-W016577S3
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1-Bromoheptane-d7 is the deuterium labeled 1-Bromoheptane [1].
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- HY-13956A
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(R)-Pioglitazone-d1 ((R)-U 72107-d1) is a stabilized and deuterated R-enantiomer of pioglitazone, exhibiting pharmacological properties that are beneficial for NASH treatment, including modulation of mitochondrial function, non-steroidal anti-inflammatory effects, and glucose-lowering capabilities.
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- HY-B0258S1
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Gemfibrozil-d6-1 (CI-719-d6-1) is the deuterium labeled Gemfibrozil (HY-B0258). Gemfibrozil is an activator of PPAR-α, used as a lipid-lowering agent; Gemfibrozil is also a nonselective inhibitor of several P450 isoforms, with Ki values for CYP2C9, 2C19, 2C8, and 1A2 of 5.8, 24, 69, and 82 μM, respectively [1].
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- HY-B0223S4
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Albendazole-d3-1 (SKF-62979-d3-1) is the deuterium labeled Albendazole (HY-B0223). Albendazole (SKF-62979) is an orally active and broad-spectrum parasiticide with high effectiveness and low host toxicity, is used for the research of gastrointestinal parasites in humans and animals. Albendazole induces apoptosis and autophagy in cancer cells. Albendazole also inhibits tubulin polymerization and HIF-1α, VEGF expression, has antioxidant activity, and inhibits the glycolytic process in cancer cells [1] .
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- HY-14281S2
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Trilostane-d3-1 (Win 24540-d3-1) is deuterium-labeled Trilostane (HY-14281) [1].
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- HY-B0196S1
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Venlafaxine-d6-1 is deuterium labeled Venlafaxine. Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant [1].
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- HY-W099521S
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1-Chlorooctane-d17 is the deuterium labeled 1-Chlorooctane [1].
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- HY-W008625S1
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1-Bromohexadecane-d33 is the deuterium labeled 1-Bromohexadecane [1].
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- HY-15917S1
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DL-Dithiothreitol-d10-1 is the deuterated form of DL-dithiothreitol. DL-Dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. DL-Dithiothreitol is oxidized to form a stable six-membered ring with an internal disulfide bond [1] .
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- HY-B0451AS3
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Dopamine-d2-1 (hydrochloride) is the deuterium labeled Dopamine hydrochloride [1].
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- HY-17376S1
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Ezetimibe-d4-1 is deuterium labeled Ezetimibe. Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.
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- HY-15780S1
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Brexpiprazole-d8-1 (OPC-34712-d8-1) is the deuterium labeled Brexpiprazole (HY-15780) [1]. Brexpiprazole (OPC-34712), an atypical orally active antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine D2L receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM. Brexpiprazole also shows potent antagonist activity at human noradrenergic α1B (Ki=0.17 nM) and α2C receptors (Ki=0.59 nM) .
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- HY-10846S1
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Delamanid-d4-1 is deuterated labeled Delamanid.Delamanid, a newer mycobacterial cell wall synthesis inhibitor, inhibits the synthesisi of mucolic acids [1].
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- HY-17386S2
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Rosiglitazone-d4-1 (BRL 49653-d4-1) is deuterium-labeled Rosiglitazone (HY-17386) [1].
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- HY-W032013S2
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1-Octanol-d2-1 is deuterated labeled 1-Octanol (HY-W032013). 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents [1]. 1-Octanol is a highly attractive biofuel with diesel-like properties .
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- HY-14956S1
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Nemonoxacin-d3-1 is the deuterium labeled Nemonoxacin. Nemonoxacin (TG-873870) is an orally active and potent broad-spectrum antibiotic. Nemonoxacin shows good inhibitory activity against different species of staphylococci, streptococci, and enterococci, Neisseria gonorrhoeae, and Haemophilus influenza. Nemonoxacin can be used in the study of bacterial infections and community-acquired pneumonia [1] .
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- HY-W725472
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1,3-Dibromobenzene-d4 (m-Dibromobenzene-d4) is the deuterium labeled 1,3-Dibromobenzene.
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- HY-17430S1
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Amprenavir-d4-1 is deuterium labeled Amprenavir. Amprenavir (VX-478) is a HIV protease inhibitor (Ki=0.6 nM) used to treat HIV infection. Amprenavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.09 μM.
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- HY-B0197S
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Naratriptan-d3 (GR-85548A-d3) is the deuterium labeled Naratriptan (HY-B0197). Naratriptan is a selective 5-HT1B/1D receptor agonist. Naratriptan is peripherally active and has good oral bioavailability, inducing cranial artery vasoconstriction by activating 5-HT1B/1D receptors (EC50=0.11 μM for dog basilar artery). Naratriptan also inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation and reduces sterile inflammation. Naratriptan is mainly used in the research of acute migraine, targeting cranial vascular and neuroinflammatory mechanisms [1] .
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-
- HY-N1380S4
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Guaiacol-d4-1 is the deuterium labeled Guaiacol [1]. Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation [1]. Anti-inflammatory activity .
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-
- HY-W101642S
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1,3-Diisopropylbenzene-d18 is the deuterium labeled 1,3-Diisopropylbenzene [1].
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-
- HY-W009450S
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1,7-Dibromoheptane-d14 (Heptamethylene dibromide-d14) is the deuterium labeled 1,7-Dibromoheptane (HY-W009450). 1,7-Dibromoheptane is a PROTAC linker that can be used in the synthesis of PROTACs.
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-
- HY-76025S
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1,4-Dibromobenzene-d4 is a deuterium labeled 1,4-Dibromobenzene. 1,4-Dibromobenzene is used as a fumigant and as a chemical intermediate for pharmaceuticals. Inhalation exposure gives rise to dizziness and chokingwhereas contact with skin or eye produces inflammation and burning in humans [1].
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-
- HY-113139S
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1-Methylinosine-d3 (N1-MetHYlinosine-d3) is the deuterium labeled 1-Methylinosine. 1-Methylinosine is a modified nucleotide located at position 37 of eukaryotic tRNA, 3' to the tRNA anticodon. 1-Methylinosine is a minor metabolite of 1-methyladenosine (HY-113081). The level of 1-Methylinosine is significantly elevated in urine samples from breast cancer models.
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-
- HY-109128S2
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Danicamtiv-d3-1 (MYK-491-d3-1) is a deuterated labeled Danicamtiv (HY-109128). Danicamtiv (MYK-491), an inotropic agent, is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency [1].
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-
- HY-W723927
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1-Bromohexadecane-d4 (n-Hexadecyl bromide-d4) is the deuterium labeled 1-Bromohexadecane.
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-
- HY-W014559S3
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1-Bromononane-d4-1 is the deuterium labeled 1-Bromononane [1].
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-
- HY-W099504S1
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1-Heptanol-d7 is the deuterium labeled 1-Heptanol [1].
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-
- HY-10284S3
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Linagliptin-d3-1 (BI 1356-d3-1) is the deuterium labeled Linagliptin (HY-10284). Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM [1].
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-
- HY-W014286S
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1,3-Diphenylurea-d10 is the deuterium labeled 1,3-Diphenylurea [1].
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-
- HY-B0260S6
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Methylprednisolone-d3-1 (U 7532-d3-1) is the deuterium labeled Methylprednisolone (HY-B0260). Methylprednisolone (U 7532) is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels [1].
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-
- HY-Y1806S1
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1,3-Dibromopropane-d6 (Trimethylene dibromide-d6) is the deuterium labeled 1,3-Dibromopropane (HY-Y1806). 1,3-Dibromopropane (Trimethylene dibromide) is a standard substrate. 1,3-Dibromopropane can be used for haloalkane dehalogenase DmmA assays.
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-
- HY-122272S2
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Paroxetine-d6-1 is a deuterated labeled Paroxetine [1]. Paroxetine, a phenylpiperidine derivative, is a potent and selective serotonin reuptake inhibitor (SSRI). Paroxetine is a very weak inhibitor of norepinephrine (NE) uptake but it is still more potent at this site than the other SSRIs .
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-
- HY-W012477S
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1-Hydroxycyclohexyl phenyl ketone-d5 (Photoinitiator-184-d5) is the deuterium labeled 1-Hydroxycyclohexyl phenyl ketone (HY-W012477) [1].
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-
- HY-41676S
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4-Chlorobenzonitrile-d4 is the deuterium labeled 4-Chlorobenzonitrile [1].
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-
- HY-W719338
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Pentane-1,2-diol-d7 ((±)-Pentane-1,2-diol-d7; 1,2-Dihydroxypentane-d7; 1,2-Pentylene glycol-d7; Diol PD-d7; Hydrolite 5-d7; NSC 513-d7; 1,2-Pentanediol-d7) is the deuterium labeled Pentane-1,2-diol (HY-Y1249).
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-
- HY-Y1052S
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N-Dodecylbenzene-d30 is the deuterium labeled N-Dodecylbenzene [1].
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-
- HY-Y0678S
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1,3,5-Trimethoxybenzene-d3 (Trimethyl phloroglucinol-d3) is the deuterium labeled 1,3,5-Trimethoxybenzene (HY-Y0678). 1,3,5-Trimethoxybenzene is a key component of the Chinese rose odor. 1,3,5-Trimethoxybenzene is synthesized in three successive methylation steps from phloroglucinol, the initial precursor [1].
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-
- HY-W004051S
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1-Bromo-2-chlorobenzene-d4 is the deuterium labeled 1-Bromo-2-chlorobenzene [1].
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-
- HY-N6709S2
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Zeranol-d5-1 (α-Zearalanol-d5-1) is the deuterium labeled Zeranol (HY-N6709). Zeranol, a metabolite of the mycoestrogen zearalenone, is an estrogen receptor agonist. Zeranol is used as a growth promoter of livestock due to its strong estrogenic activity [1] .
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-
- HY-W013049S4
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Docosanoic acid-d4-1 (Behenic acid-d4-1) is the deuterium labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans [1] .
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-
- HY-W012856S
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1-Ethyl-3-methylbenzene-d5 is the deuterium labeled 1-Ethyl-3-methylbenzene [1].
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-
- HY-13631ES2
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Deruxtecan-d4-1 is the deuterium labeled Adenosine Deruxtecan (HY-13631E) [1]. Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
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-
- HY-B0228S
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Adenosine-d is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation [1] .
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-
- HY-N0384S4
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Homovanillic acid-d3-1 (Vanilacetic acid-d3-1) is deuterated labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency [1].
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- HY-N0210S11
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D-Galactose-d2-1 is the deuterium labeled D-Galactose. D-Galactose is a natural aldohexose and C-4 epimer of glucose.
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- HY-B1812S4
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Veratrole-d2-1 is the deuterium labeled Veratrole (HY-B1812). Veratrole (1,2-Dimethoxybenzene) is a key compound that widely exists in plants and attracts pollinators. The release of Veratrole has a circadian rhythm and plays an important role in plant reproduction, species differentiation, and interactions with pollinators. In addition, Veratrole can be demethylated by cytochrome P-450 in Streptomyces setonii [1] .
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-
- HY-W142175S
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1-Butynylbenzene-d5 is the deuterium labeled 1-Butynylbenzene [1]. 1-Butynylbenzene-d5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-W098448S
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1-Methylazepan-2-one-d3 is the deuterium labeled 1-Methylazepan-2-one [1].
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-
- HY-N0210S7
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D-Galactose-d-2 is the deuterium labeled D-Galactose. D-Galactose is a natural aldohexose and C-4 epimer of glucose.
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-
- HY-W016931S
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1-Bromo-4-chlorobutane-d8 is the deuterium labeled 1-Bromo-4-chlorobutane [1].
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-
- HY-122277S
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1'-Hydroxy bufuralol-d9 is a deuterium labeled 1'-Hydroxy bufuralol (HY-122277). 1'-Hydroxy bufuralol is the main metabolite of Bufuralol (HY-105124) by the cytochrome P450 isoenzymes 2D1 and 2D2 (CYP2D1/2). 1'-Hydroxy bufuralol can be used to determine CYP2D1/2 enzyme activity [1] .
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-
- HY-W017554S
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1-Chloro-2-methoxybenzene-d3 is the deuterium labeled 1-Chloro-2-methoxybenzene [1].
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-
- HY-W242724
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1,4-Dibromo-butane-1,1,2,2,3,3,4,4-d8 is the deuterium labeled 1,4-Dibromo-butane [1].
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- HY-N7092S18
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D-Fructose-d2-1 is the deuterium labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants [1].
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- HY-W130478S
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1-Phenylhexane-d5 is the deuterium labeled 1-Phenylhexane [1].
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-
- HY-W865379
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(S)-Avadomide-d1 (SP-3164; CC 122-d1) is deuterated labeled (S)-Avadomide-d1 (HY-W865379).
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-
- HY-W015609S
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1-(2-Methoxyphenyl)ethanone-d3 (2'-Methoxyacetophenone-d3) is deuterium-labeled 1-(2-Methoxyphenyl)ethanone (HY-W015609) [1].
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- HY-N0210S8
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D-Galactose-d-3 is the deuterium labeled D-Galactose. D-Galactose is a natural aldohexose and C-4 epimer of glucose.
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-
- HY-W015849S
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1-Fluoro-4-methoxybenzene-d4 is the deuterium labeled 1-Fluoro-4-methoxybenzene [1].
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- HY-W017522S5
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Adipic acid-d4-1 (Hexanedioic acid-d4-1) is the deuterium labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc [1] .
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-
- HY-34487S3
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1,3-Dimethoxybenzene-d3 (Resorcinol dimethyl ether-d3) is the deuterium labeled 1,3-Dimethoxybenzene (HY-34487). 1,3-Dimethoxybenzene belongs to the class of organic compounds known as dimethoxybenzenes. 1,3-Dimethoxybenzene is an intermediate in synthesis of organic compounds [1].
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-
- HY-W724366
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1-Ethyl-2-methylbenzene-d5 (2-Methylethylbenzene-d5) is the deuterium labeled 1-Ethyl-2-methylbenzene.
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- HY-109506S3
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DPPC-d9-1 is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers [1]. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice .
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- HY-66011AS3
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Moxifloxacin-d3-1 hydrochloride (BAY 12-8039-d3-1) is a deuterium labeled Moxifloxacin (HY-66011A). Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia [1] .
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- HY-W010004S
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1-Bromo-3-chlorobenzene-d4 (3-Chlorobromobenzene-d4) is a deuterium labeled 1-Bromo-3-chlorobenzene.
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-
- HY-W700931
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1-Methoxy-2-(2-methoxyethoxy)ethane-d6 (Dimethylcarbitol-d6) is the deuterium labeled 1-Methoxy-2-(2-methoxyethoxy)ethane (HY-Y1227).
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-
- HY-W016152S
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1-Bromo-3-methoxybenzene-d3 is the deuterium labeled 1-Bromo-3-methoxybenzene.
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- HY-114041S1
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Resolvin E1-d4-1 is the deuterium labeled Resolvin E1. Resolvin E1 (RvE1), a potent endogenous pro-resolving mediator of inflammation, is derived from omega-3 fatty acid eicosapentaenoic acid (EPA). Resolvin E1 is endogenously biosynthesized from EPA in the presence of Aspirin during the spontaneous resolution phase of acute inflammation, where specific cell-cell interactions occur. Resolvin E1 possesses unique counterregulatory actions that inhibit polymorphonuclear leukocyte (PMN) transendothelial migration. Resolvin E1 also acts as a potent inhibitor of leukocyte infiltration, dendritic cell migration, and IL-12 production [1] .
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- HY-W342440S
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1,1-Diethoxynonane-d10 is a deuterated labeled 1,1-Diethoxynonane [1].
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- HY-107343S1
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Docosahexaenoic acid ethyl ester-d5-1 is the deuterium labeled Docosahexaenoic acid ethyl ester. Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) is a 90% concentrated ethyl ester of docosahexaenoic acid manufactured from the microalgal oil. Docosahexaenoic acid ethyl ester enhances 6-hydroxydopamine-induced neuronal damage by induction of lipid peroxidation in mouse striatum. Docosahexaenoic acid (DHA) is a key component of the cell membrane, and its peroxidation is inducible due to the double-bond chemical structure. Docosahexaenoic acid has neuroprotective effects [1] .
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- HY-W725429
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1,5-Dihydroxynaphthalene-d6 (Naphthalene-1,5-diol-d6) is the deuterium labeled 1,5-Dihydroxynaphthalene (HY-Y0825).
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- HY-Y1805S
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1,2,3,4-Tetrahydronaphthalene-d4 (Tetralin solvent-d4) is the deuterium labeled 1,2,3,4-Tetrahydronaphthalene (HY-Y1805) [1].
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- HY-W015301S1
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Dimethyl adipate-d4-1 (Hexanedioic acid dimethyl ester-d4-1) is the deuterium labeled Dimethyl adipate (HY-W015301). Dimethyl adipate is an aliphatic dicarboxylate compound. Dimethyl adipate is mainly used as a plasticizer and an intermediate in organic synthesis.
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- HY-W712592
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1-Ethylpyrrolidine-2,5-dione-d5 (N-Ethylsuccinimide-d5) is the deuterium labeled 1-Ethylpyrrolidine-2,5-dione (HY-W353513).
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- HY-Y1227S
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1-Methoxy-2-(2-methoxyethoxy)ethane-d14 (Dimethylcarbitol-d14) is the deuterium labeled 1-Methoxy-2-(2-methoxyethoxy)ethane.
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- HY-W094751S
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1-Pyrenamin-d9 is the deuterium labeled 1-Pyrenamin [1].
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- HY-W052227S
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Fmoc-DL-Ala-OH-d is the deuterium labeled DL-Alanine-2-N-fmoc.
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- HY-W014409S
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1,2,4-Benzenetricarboxylic acid-d3 (Trimellitic acid-d3) is the deuterium labeled 1,2,4-Benzenetricarboxylic acid.
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-
- HY-W699416
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1-Naphthoic acid-d7 (Naphthalene-1-carboxylic acid-d7) is the deuterium labeled 1-Naphthoic acid (HY-Y0236). Naphthalene-1-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W724365
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1-Bromo-2-methoxyethane-d3 (2-Methoxyethyl Bromide-d3) is the deuterium labeled 1-Bromo-2-methoxyethane,98%(stabilized with Na2CO3).
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- HY-W009570S
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1-Bromo-4-(trifluoromethoxy)benzene-d4 (P-Bromotrifluoromethoxybenzene-d4) is the deuterium labeled 1-Bromo-4-(trifluoromethoxy)benzene.
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- HY-15025S2
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Sildenafil-d3-1 (UK-92480-d3-1) is deuterium labeled Sildenafil-d3. Sildenafil (UK-92480) is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM.
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- HY-W012934S
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1-Ethylpyrrolidin-2-one-d5 (N-Ethyl-pyrrolidone-d5) is deuterium labeled 1-Ethylpyrrolidin-2-one [1].
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-
- HY-126967AS
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1-Palmitoyl-sn-glycerol 3-phosphate-d9 is the deuterium labeled 1-Palmitoyl-sn-glycerol 3-phosphate (1-Palmitoyl LPA). 1-Palmitoyl LPA is an analog of LPA that contains palmitic acid at the sn-1 position.
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- HY-112530S
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1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine-d70 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine. 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (DSPE) is a phosphoethanolamine (PE) lipid that can be used in the synthesis
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- HY-W011883S
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1,3-Dibromo-5-fluorobenzene-d3 is the deuterium labeled 1,3-Dibromo-5-fluorobenzene [1].
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- HY-13936S
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1-Methylimidazoleacetic acid (1-Methylimidazole-4-acetic acid)-d3 is deuterium labeled 1-Methylimidazoleacetic acid (HY-13936). 1-Methylimidazoleacetic acid is a Histamine (HY-B1204) metabolite. 1-Methylimidazoleacetic acid serves as a biomarker for the detection of mastocytosis [1].
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- HY-113482S
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1β-Hydroxydeoxycholic Acid-d5 is the deuterium labeled 1β-Hydroxydeoxycholic Acid [1].
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- HY-Y0566S
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1,4-Diazabicyclo[2.2.2]octane-d12 is the deuterium labeled 1,4-Diazabicyclo[2.2.2]octane [1].
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-
- HY-W654320
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Piperin-d10 is deuterium labeled Piperine. Piperine is an alkaloid, can be isolated from pepper. Piperine can inhibit the activity of P-glycoprotein and CYP3A4. Piperine inhibits HeLa cells with an IC50 of 61.94±0.054 μg/mL [1] .
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- HY-11018S1
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Risperidone-d4-1 (R 64 766-d4-1) is the deuterium labeled Risperidone (HY-11018). Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively.
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- HY-113424AS
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1,2-Dioleoyl-sn-glycero-3-phosphocholine-d9 is deuterium labeled 1,2-Dioleoyl-sn-glycero-3-phosphocholine. 1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelle
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- HY-W011885S
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1-Dodecylpyrrolidin-2-one-d6 (N-Lauryl-2-pyrrolidone-d6) is deuterium-labeled 1-Dodecylpyrrolidin-2-one (HY-W011885) [1].
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- HY-N0229S16
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L-Alanine-d3-1 is the deuterium labeled L-Alanine [1]. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system .
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- HY-128429S
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trans-2-Hexenal-d2-1 is the deuterium labeled trans-2-Hexenal (HY-128429). trans-2-Hexenal ((E)-2-Hexenal) is a volatile compound widely present in fresh plants, vegetables, and fruits, with a unique leafy aroma. trans-2-Hexenal has antifungal activity and can also inhibit the germination of soybean seeds and the growth of seedlings. In addition, trans-2-Hexenal can be used to determine low-molecular-weight carbonyl compounds that are reactive with biological nucleophiles in biological samples [1].
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- HY-W740373
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1-Methylpiperidin-4-ol-d4 (N-Methyl-4-piperidinol-d4) is the deuterium labeled 1-Methylpiperidin-4-ol (HY-W018626). 1-Methylpiperidin-4-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-N0215S13
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L-Phenylalanine-d is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals [1] .
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- HY-W009719S
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1-Bromo-2,3-dichlorobenzene-d3 is the deuterium labeled 1-Bromo-2,3-dichlorobenzene [1].
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- HY-178735S
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1,2-Dioleoyl-sn-glycero-3-phosphocholine-d62 (DOPC-d62) is the deuterium labeled 1,2-Dioleoyl-sn-glycero-3-phosphocholine.
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- HY-W716213
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1-(2,4-Dimethoxyphenyl)ethanone-d6 (2',4'-Dimethoxyacetophenone-d6) is the deuterium labeled 1-(2,4-Dimethoxyphenyl)ethanone (HY-W040456).
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- HY-W009981S
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1-Bromo-2,4-difluorobenzene-d3 is the deuterium labeled 1-Bromo-2,4-difluorobenzene [1].
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- HY-130462S3
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1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d62 (POPC-d64) is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers [1] [1] .
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- HY-B0402S
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Amantadine-d15 is the deuterium labeled Amantadine. Amantadine (1-Adamantanamine) is an antiviral agent with activity against influenza A viruses. Amantadine blocks the proton flow through the M2 ion channel (M2 proton channel of influenza A) and thus prevents the release of viral RNA into the cytoplasm of the infected cells. Amantadine is an antiparkinsonian agent [1] .
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- HY-W768340
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Sucrose- 13C6-1 is 13C labeled Sucrose. Sucrose (D-(+)-Saccharose) is a disaccharide which is composed of two monosaccharides, glucose and fructose. Sucrose can be applied in some animal models, including metabolic disease, obesity, diet on preference, and diabetes, et al [1].
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- HY-B0228S8
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Adenosine-d-2 is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular phys
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- HY-130462S
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1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d31 is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for
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- HY-79779S
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1-Bromo-4-(bromomethyl)benzene-d6 is the deuterium labeled 1-Bromo-4-(bromomethyl)benzene [1].
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- HY-W766801
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1-Linoleoyl-3-chloropropanediol-d5 (Rac-1-Linoleoyl-3-chloropropanediol-d5) is deuterium labeled 1-Linoleoyl-3-chloropropanediol (HY-W777865). 1-Linoleoyl-3-chloropropanediol is a lipid product [1].
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- HY-143671S
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1-Stearoyl-2-arachidonoyl-sn-glycero-3-PE-d11 is the deuterium labeled 1-Stearoyl-2-arachidonoyl-sn-glycero-3-PE [1].
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- HY-130462S1
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1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d82 is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for
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- HY-W142820S
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1,1,3,3-Tetraethoxypropane-d2 is the deuterium labeled 1,1,3,3-Tetraethoxypropane [1].
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- HY-W015784S
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1,4-Benzenedimethanol-d4 is the deuterium labeled 1,4-Benzenedimethanol [1].
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- HY-W700950
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1-(4-Chlorophenyl)cyclobutanecarbonitrile-d6 (1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile-d6) is the deuterium labeled 1-(4-Chlorophenyl)cyclobutanecarbonitrile (HY-W010002).
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- HY-B0402S1
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Amantadine-d6 is the deuterium labeled Amantadine [1]. Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
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- HY-W017142S
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1-(Benzyloxy)propan-2-ol-d6 (3-(Benzyloxy)-2-propanol-d6) is the deuterium labeled 1-(Benzyloxy)propan-2-ol (HY-W017142).
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- HY-79779S1
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1-Bromo-4-(bromomethyl)benzene-d4 is the deuterium labeled 1-Bromo-4-(bromomethyl)benzene [1].
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- HY-130462S4
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1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d9 (POPC-d9) is the deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (HY-130462). 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers [1].
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- HY-W097453S2
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6-(Methylthio)purine-d3-1 is the deuterium labeled 6-(Methylthio)purine [1].
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- HY-130462S5
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1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d62 (POPC-d62) is the deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (HY-130462). 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers [1].
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- HY-Y0921S3
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(±)-1,2-Propanediol- 13C3 is 13C labeled (±)-1,2-Propanediol (HY-Y0921). (±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish [1] .
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- HY-125783S1
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1-Palmitoyl-sn-glycero-3-phosphocholine-d31 (16:0 Lyso PC-d31) is deuterium labeled 1-Palmitoyl-sn-glycero-3-phosphocholine (HY-125783). 1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis [1] .
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- HY-W110726S1
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1-Octen-3-one-d3 is deuterated labeled 1-Octen-3-one.
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- HY-178791S
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1,2-Diheptanoyl-sn-glycero-3-phosphoethanolamine-d26 (DH7PE-d26) is the deuterium labeled 1,2-Diheptanoyl-sn-glycero-3-phosphoethanolamine.
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- HY-W013376S
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Norcyclizine-d8 is the deuterium labeled Norcyclizine [1].
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- HY-125783S
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1-Palmitoyl-sn-glycero-3-phosphocholine-d9 (16:0 Lyso PC-d9) is deuterium labeled 1-Palmitoyl-sn-glycero-3-phosphocholine (HY-125783). 1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis [1] .
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- HY-107737S3
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1,2-DLPC-d9 (1,2-Dilauroyl-sn-glycero-3-phosphocholine-d9) is the deuterium labeled 1,2-DLPC. 1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. 1,2-DLPC is a phospholipid used in the synthesis of liposomes. 1,2-DLPC enhances fat breakdown and apoptosis in fat cells through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance through PPARα-mediated inflammation in muscle cells [1] .
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- HY-W110726S
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1-Octen-3-one-d5 is deuterated labeled 1-Octen-3-one.
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- HY-125783S2
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1-Palmitoyl-sn-glycero-3-phosphocholine-d49 (16:0 Lyso PC-d49) is deuterium labeled 1-Palmitoyl-sn-glycero-3-phosphocholine (HY-125783). 1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis [1] .
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- HY-W777094
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1-Acetyl-4-(4-hydroxyphenyl)piperazine-d8 (Tetraethoxy C methyl propane-d8) is the deuterium labeled 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone (HY-W014037).
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- HY-W590534S
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1-Palmitoyl-sn-glycero-3-phosphocholine-d3 is a deuterated phosphocholine.
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- HY-107737S2
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1,2-DLPC-d46 (1,2-Dilauroyl-sn-glycero-3-phosphocholine-d46) is the deuterium labeled 1,2-DLPC. 1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. 1,2-DLPC is a phospholipid used in the synthesis of liposomes. 1,2-DLPC enhances fat breakdown and apoptosis in fat cells through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance through PPARα-mediated inflammation in muscle cells [1] .
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- HY-W1115209
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1,3,5-Tribromo-2-iodobenzene-d2 (2,4,6-Tribromoiodobenzene-d2) is a deuterium labeled 1,3,5-Tribromo-2-iodobenzene.
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- HY-W105111S
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1-Bromo-2,3,5-trichlorobenzene-d2 is the deuterium labeled 1-Bromo-2,3,5-trichlorobenzene [1].
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- HY-W014431S
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1-Bromo-3-chloro-5-fluorobenzene-d3 is the deuterium labeled 1-Bromo-3-chloro-5-fluorobenzene [1].
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- HY-W015824S3
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DL-Aspartic acid- 13C1 is the 13C labeled DL-Aspartic acid [1].
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- HY-N0210S12
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D-Galactose- 13C,d is the deuterium and 13C labeled D-Galactose. D-Galactose is a natural aldohexose and C-4 epimer of glucose.
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- HY-107737S
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1,2-DLPC-d55 (1,2-Dilauroyl-sn-glycero-3-phosphocholine-d55) is the deuterium labeled 1,2-DLPC. 1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. 1,2-DLPC is a phospholipid used in the synthesis of liposomes. 1,2-DLPC enhances fat breakdown and apoptosis in fat cells through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance through PPARα-mediated inflammation in muscle cells [1] .
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- HY-N7092S23
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D-Fructose- 13C3-1 is 13C-labeled D-Fructose (HY-N7092). D-Fructose (D(-)-Fructose) is a natural monosaccharide found in many plants.
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- HY-B0151S2
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Pregnenolone-d4-1 is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication [1] . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
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- HY-145473S
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1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11 (15(S)-HETE-SAPE-d11) is deuterium labeled 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE. 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (HY-B2219) at the sn-1 position and 15(S)-HETE at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 (HY-N6687) by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE) by 15-LO. Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes [1].
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- HY-W013504S
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1-Bromo-4-(trifluoromethyl)benzene-d4 is the deuterium labeled 1-Bromo-4-(trifluoromethyl)benzene [1].
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- HY-B0896S2
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Glyceryl Triacetate-d9 is the deuterium labeled Triacetin [1]. Triacetin is an artificial chemical compound, is the triester of glycerol and acetic acid, and is the second simplest fat after triformin.
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- HY-W654064
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Azithromycin- 13C,d3-1 is a deuterated labeled Azithromycin [1].
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- HY-Y1275S
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N-Methylpyrrolidone-d9 (NMP-d9) is deuterium labeled N-Methylpyrrolidone. N-Methylpyrrolidone (1-Methyl-2-pyrrolidinone), a five-membered cyclic amide, is an orally active organic polar solvent with teratogenicity and toxicity. N-Methylpyrrolidone is low in acute toxicity with a LD50 value of 3914 mg/kg in rats and of 4050 mg/kg in mice. N-Methylpyrrolidone is extensively used in the manufacture of adhesives, paints, fuels, and pharmaceuticals [1] .
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- HY-W192474S
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1-(Furan-2-yl)ethane-1-thiol-d3 is deuterated labeled 1-(Furan-2-yl)ethane-1-thiol.
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- HY-Y0743S
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1-(Pyridin-2-yl)ethan-1-one-d6 is deuterated labeled 1-(Pyridin-2-yl)ethan-1-one.
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- HY-W013948S
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1-(2,4-Dinitrophenyl)-2-propylidenehydrazine-d3 is the deuterium labeled 1-(2,4-Dinitrophenyl)-2-propylidenehydrazine [1].
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- HY-W654409
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1,1,1,3,3,3-Hexafluoropropan-2-ol-d2 (Hexafluoroisopropyl alcohol-d2) is deuterium labeled 1,1,1,3,3,3-Hexafluoropropan-2-ol [1].
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- HY-112675S
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4-Octyl itaconate- 13C5-1 is 13C-labeled 4-Octyl itaconate (HY-112675). Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
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- HY-Y0219S1
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NSC 83128-d3 is the deuterium labeled NSC 83128 [1].
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- HY-B0896S1
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Triacetin-d5 is the deuterium labeled Triacetin. Triacetin is an artificial chemical compound, is the triester of glycerol and acetic acid, and is the second simplest fat after triformin.
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- HY-W009293S
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1-(Bis(4-fluorophenyl)methyl)piperazine-d4 (N-(4,4-Difluorobenzhydryl)piperazine-d4) is the deuterium labeled 1-(Bis(4-fluorophenyl)methyl)piperazine.
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- HY-W777599
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(±)-Naproxen- 13C,d3-1 ((Rac)-Naproxen- 13C,d3-1) is 13C and deuterium labeled (±)-Naproxen [1].
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- HY-122426S2
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1-Bromoundecane-d4 is the deuterium labeled 1-Bromoundecane [1].
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- HY-W756596
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1,2-Dioctanoyl-3-chloropropanediol-d5 is deuterium labeled 1,2-Dioctanoyl-3-chloropropanediol. 1,2-Dioctanoyl-3-chloropropanediol (3-Chloropropane-1,2-diyl dioctanoate) is an ester product [1].
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- HY-W012652S
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1,2,3,4-Tetrahydroquinoxaline-d4 (Quinoxaline, 1,2,3,4-tetrahydro-d4) is the deuterium labeled 1,2,3,4-Tetrahydroquinoxaline.
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- HY-Y0531S
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1-Adamantanol-d15 (Tricyclo[3.3.1.1~3,7~]decan-1-ol-d15) is the deuterium labeled 1-Adamantanol (HY-Y0531). 1-Adamantanol (Tricyclo[3.3.1.1~3,7~]decan-1-ol) is a hydroxylated derivative of Adamantane (HY-N2427). 1-Adamantanol serves as a substrate for regioselective hydroxylation reactions in Streptomyces strain SA8. 1-Adamantanol can form acrylate derivatives, which are used as photoresist layer materials [1].
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- HY-N0537S12
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Xylose-d-3 is the deuterium labeled Xylose.
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- HY-125783S3
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1-Palmitoyl-sn-glycero-3-phosphocholine-d9-1 (16:0 Lyso PC-d9-1) is deuterium labeled 1-Palmitoyl-sn-glycero-3-phosphocholine (HY-125783). 1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis [1] .
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- HY-N0229S4
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1 Publications Verification
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L-Alanine- 13C,d is the 13C- and deuterium labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
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- HY-D0837S
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Imidazole-d4 is the deuterium labeled Imidazole [1].
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- HY-115702S
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1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine-d4 ((Rac)-PAF (C16)-d4) is the deuterium labeled 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine is an endogenous inflammatory lipid mediator. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine acts as a high-affinity agonist for PAFR (GPCR), inducing platelet aggregation, vascular permeability, and leukocyte chemotaxis at extremely low concentrations. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine exerts its effects via cell surface receptors to regulate inflammation [1].
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- HY-W051547S1
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1-(2-Chloropyridin-3-yl)ethanol-d3 (2-Chloro-3-(1-hydroxyethyl)pyridin-d3) is the deuterium labeled 1-(2-Chloropyridin-3-yl)ethanol.
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- HY-N0537S13
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Xylose-d-4 is the deuterium labeled Xylose.
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- HY-10002AS2
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(1S)-Calcitriol-d6 (1α,25-Dihydroxy-3-epi-vitamin D3-d6) is the deuterium labeled (1S)-Calcitriol (HY-10002A). (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion [1].
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- HY-10003S
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Alfacalcidol-d7 is the deuterium labeled Alfacalcidol. Alfacalcidol (1-hydroxycholecalciferol) is a vitamin D active metabolites, acts as a non-selective VDR activator medication, and widely be used in the management of osteoporosis [1] .
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- HY-W754348
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1-(2,6-Dimethylphenoxy)propan-2-one-d5 (1-(2,6-Dimethylphenoxy)acetone-d5) is the deuterium labeled 1-(2,6-Dimethylphenoxy)propan-2-one (HY-W270592).
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- HY-15029S1
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(±)-Naproxen-d3-1 is the deuterium labeled (±)-Naproxen [1].
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- HY-W051547S
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1-(2-Chloropyridin-3-yl)ethanol-d4 (2-Chloro-3-(1-hydroxyethyl)pyridine-d4) is the deuterium labeled 1-(2-Chloropyridin-3-yl)ethanol.
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- HY-10002AS
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(1S)-Calcitriol-d3 (1α,25-Dihydroxy-3-epi-vitamin D3-d3) is the deuterium labeled (1S)-Calcitriol (HY-10002A). (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion [1].
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- HY-Y0479S3
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L-Lactic acid-2- 13C1 is the 13C-labeled L-Lactic acid (HY-Y0479). L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid [1].
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- HY-146829S
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1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphate-d7 (sodium) is deuterium labeled 1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphate (sodium).
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- HY-W718042
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1-Lauroyl-2-decanoyl-3-chloropropanediol-d5 is a deuterated 3-monochloropropanediol (3-MCPD) glycidyl ester.
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- HY-W768181
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1,5-Anhydrosorbitol- 13C6 (1,5-Anhydro-D-glucitol- 13C6) is the 13C-labeled 1,5-Anhydrosorbitol (HY-113075). 1,5-Anhydrosorbitol is a short-term marker for glycemic control.
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- HY-142555S
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Bisphenol A monosulfate-d6 (sodium) is the deuterium labeled Bisphenol A monosulfate sodium [1].
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- HY-100441S1
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Treprostinil- 13C2,d is the 13C- and deuterium labeled Treprostinil. Treprostinil (UT-15) is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively.
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- HY-W654074
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1,2-Dilauroyl-3-chloropropanediol-d5 (1,1′-[1-(Chloromethyl)-1,2-ethanediyl] didodecanoate-d5) is the deuterium labeled 1,2-Dilauroyl-3-chloropropanediol (HY-W587507). 1,2-Dilauroyl-3-chloropropanediol (1,1′-[1-(Chloromethyl)-1,2-ethanediyl] didodecanoate) is an ester product.
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- HY-112005S
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DOPE-d62 (Dioleoylphosphatidylethanolamine-d62) is the deuterium labeled DOPE (HY-112005). DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA [1].
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- HY-W010265S
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Butyrophenone-d5 is the deuterium labeled Butyrophenone [1].
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- HY-W767978
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1-(4,4-Dimethylthiochroman-6-yl)ethanone-d8 (6-Acetyl-4,4-dimethylthio-chroman-d8) is the deuterium labeled 1-(4,4-Dimethylthiochroman-6-yl)ethanone (HY-I0187).
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- HY-178810S
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1,2-Dioleoyl-sn-glycero-3-phospho-L-serine-d62 ammonium (DOPS-NH3-d62) is the deuterium labeled 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine ammonium.
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- HY-130462S2
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1-Palmitoyl-2-oleoyl-sn-glycero-3-PC- 13C16 (POPC- 13C16) is 13C labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers [1] [1] .
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- HY-178403S
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1,3-Diethyl-1,3-diphenylurea-d10-1 (N,N-Diethyl-N,N-diphenylurea-d10-1) is the deuterium labeled 1,3-Diethyl-1,3-diphenylurea.
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-
- HY-W770203
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1-Oleoyl-2-linoleoyl-rac-glycerol-d5 (DG(18:1/0:0/18:2)-d5) is the deuterium labeled 1-Oleoyl-2-linoleoyl-rac-glycerol (HY-W777107). 1-Oleoyl-2-linoleoyl-rac-glycerol (DG(18:1/0:0/18:2)) is a diacylglycerol, which is composed of a linoleic acid and an oleic acid. 1-Oleoyl-2-linoleoyl-rac-glycerol can be found in dry-cured ham, and acts as the food additive [1].
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- HY-B0456S1
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Riboflavin-5-Phosphate- 13C4, 15N2-1 is the 13C-labeled and 15N-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
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- HY-W101971S
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1-(4-Chlorophenyl)-2-methylpropan-2-ol-d6 (1-(4-Chlorophenyl)-2-methyl-2-propanol-d6) is the deuterium labeled 1-(4-Chlorophenyl)-2-methylpropan-2-ol (HY-W101971).
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- HY-Y1039S
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1-Stearoyl-rac-glycerol-d40 is the deuterium labeled 1-Stearoyl-rac-glycerol [1].
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- HY-109541S5
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1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d67 is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine
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- HY-W743123
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1,3-Dipalmitin-d5 (1,3-Dipalmitoylglycerol-d5) is a deuterium labeled 1,3-Dipalmitin (HY-128792). 1,3-Dipalmitin (1,3-Dipalmitoylglycerol) is a cerebroside that can be found in Typhonium giganteum Engl [1].
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- HY-109541S3
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Colfosceril miristate-d13 (DMPC-d13) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery [1] .
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- HY-N0229S19
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L-Alanine-1,2- 13C2 (Alanine- 13C2) is 13C labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
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- HY-B0166S8
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L-Ascorbic acid- 13C6-1 (L-Ascorbate-1; Vitamin C- 13C6-1) is a 13C labeled L-Ascorbic acid (HY-B0166) [1]. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
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- HY-109541S
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Colfosceril miristate-d58 (DMPC-d58) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery [1] .
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- HY-Y1039S1
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1-Stearoyl-rac-glycerol-d35 is the deuterium labeled 1-Stearoyl-rac-glycerol.
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- HY-W751665
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1-(Adamantan-1-yl)ethan-1-one-d3 (N-Benzyl-3-carboethoxy-4-piperidone hydrochloride-d3) is the deuterium labeled 1-(Adamantan-1-yl)ethan-1-one (HY-W067624).
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- HY-109541S1
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Colfosceril miristate-d4 (DMPC-d4) is deuterium labeled Colfosceril miristate. Colfosceril miristate is a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery [1] .
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- HY-109541S4
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Colfosceril miristate-d63 (DMPC-d63) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery [1] .
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- HY-109541S2
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Colfosceril miristate-d9 (DMPC-d9) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery [1] .
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- HY-Y1217S1
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1-Cyclohexanol11 (Hydroxycyclohexane11; NSC 5471111) is the deuterium labeled 1-Cyclohexanol (HY-Y1217). 1-Cyclohexanol is an orally active Cramer Class I flavor ingredient that can be used in fragrances. 1-Cyclohexanol has a wide margin of safety and is environmentally friendly.
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- HY-114553S
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1-(5-Fluoropentyl)-1H-indole-3-carboxylic acid-d5 (5F-PB-223-Carboxyindolemetabolite-d5) is deuterium labeled 1-(5-Fluoropentyl)-1H-indole-3-carboxylic acid [1].
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- HY-W777649
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Oxypurinol- 13C, 15N2-1 (Oxipurinol- 13C, 15N2-1) is 15N and 13C labeled Oxypurinol (HY-19657). Oxipurinol, the major active metabolite of Allopurinoll (HY-B0219), is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout [1].
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- HY-Y1217S
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1-Cyclohexanol12 (Hydroxycyclohexane12; NSC 5471112) is the deuterium labeled 1-Cyclohexanol (HY-Y1217). 1-Cyclohexanol is an orally active Cramer Class I flavor ingredient that can be used in fragrances. 1-Cyclohexanol has a wide margin of safety and is environmentally friendly.
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- HY-W005926S
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1,5-Dimethyl-1H-pyrazole-4-carboxylic acid-d6 (1,5-Dimethylpyrazole-4-carboxylic acid-d6) is the deuterium labeled 1,5-Dimethyl-1H-pyrazole-4-carboxylic acid.
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- HY-78004S1
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1,2-Diphenylethane-d4 (Dibenzil-d4; s-Diphenylethane-d4; Bibenzyl-d4) is the deuterium labeled Bibenzyl (HY-78004) [1].
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- HY-W777620
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1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone- 13C,d3 (rac-Cotinine- 13C,d3) is the deuterium and 13C-labeled 1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone (HY-W588192).
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- HY-12516S2
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Desogestrel- 13C2,d2-1 (Org-2969- 13C2,d2-1) is the deuterium labeled and 13C-labeled Desogestrel (HY-12516). Desogestrel (Org-2969) is a third-generation progesterone analogue contained in many oral contraceptive preparations. Desogestrel is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups [1] .
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- HY-Y1641S
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1,2-Ethanedithiol-d4 is the deuterium labeled 1,2-Ethanedithiol [1].
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- HY-W709612
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Regorafenib N-oxide and N-desmethyl (M5)-d3-1 (N-Desmethyl regorafenib N-oxide-d3-1) is the deuterium labeled Regorafenib N-oxide and N-desmethyl (M5) (HY-108226). Regorafenib N-oxide and N-desmethyl (M5) (N-Desmethyl regorafenib N-oxide) is an active metabolite of Sorafenib (HY-10201) and can be metabolized by CYP3A4 [1].
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- HY-W392083S1
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(1,3E,5Z)-Undeca-1,3,5-triene-d5 is deuterated labeled (1,3E,5Z)-Undeca-1,3,5-triene.
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- HY-Y1309S1
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1-Naphthol-d7 (Furro ER-d7) is the deuterium labeled Naphthol (HY-Y1309). 1-Naphthol (Furro ER) is an excited state proton transfer (ESPT) fluorescent molecular probe. 1-naphthol can sense the hydrophobic domains in micellar aggregation and accurately sense the sol-gel transition. 1-naphthol can be used to study the thermally induced microenvironmental changes and hydration levels of Pluronic F127 (PF127) in different microenvironments in aqueous media [1].
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- HY-W392083S
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(1,3E,5E)-Undeca-1,3,5-triene-d5 is deuterated labeled (1,3E,5E)-Undeca-1,3,5-triene.
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- HY-Y1309S
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1-Naphthol-d8 is the deuterium labeled 1-Naphthol [1]. 1-naphthol is an excited state proton transfer (ESPT) fluorescent molecular probe .
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- HY-W718041S
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1-Lauroyl-2-decanoyl-3-chloropropanediol-13C3 is an isotope labeled 3-monochloropropanediol (3-MCPD) glycidyl ester.
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- HY-W050145S
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Levoglucosan-d7 is the deuterium labeled Levoglucosan. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature [1] .
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- HY-146726S
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Tripentadecanoin-d29 is the deuterium labeled Tripentadecanoin.
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- HY-125771S
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1-Stearoyl-sn-glycero-3-phosphocholine-d35 is deuterium labeled 1-Stearoyl-sn-glycero-3-phosphocholine (HY-125771). 1-Stearoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine that inhibits HDAC3 activity and phosphorylation of STAT3 in K562 cells. 1-Stearoyl-sn-glycero-3-phosphocholine induces apoptosis and exhibits anticancer activity in chronic myelogenous leukemia (CML) K562 cells [1].
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- HY-146737S
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Tripentadecanoin-d5 is the deuterium labeled Tripentadecanoin.
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- HY-178758S
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1-Palmitoyl-2-stearoyl-sn-glycero-3-phosphocholine-d66 (PSPC-d66) is the deuterium labeled 1-Palmitoyl-2-stearoyl-sn-glycero-3-phosphocholine.
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- HY-Y0727S
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1,5-Dibromopentane-d4 is the deuterium labeled 1,5-Dibromopentane [1].
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- HY-W726845
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1-Methyl-4-nitrosopiperazine-d11 (MNP-d11) is the deuterium labeled 1-Methyl-4-nitrosopiperazine (HY-W663740). 1-Methyl-4-nitrosopiperazine (MNP; MeNP;N-Methyl-N'-nitrosopiperazine) is a potential impurity in sartans, non-steroidal anti-inflammatory drugs (NSAIDs), and thiazide diuretics [1].
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- HY-34444S
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1,1-Dioxothiolan-d8 is the deuterium labeled 1,1-Dioxothiolan [1].
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- HY-W048482S
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rU Phosphoramidite- 13C2,d1 (DMT-2'O-TBDMS-rU phosphoramidite- 13C2,d1) is deuterium and 13C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-W777706
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1-(3,4-Dimethylphenyl)ethan-1-ol- 13C,d3 (1-(3,4-Dimethylphenyl)ethanol- 13C,d3) is the deuterium labeled and 13C-labeled 1-(3,4-Dimethylphenyl)ethan-1-ol (HY-W340128).
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- HY-Y0727S1
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1,5-Dibromopentane-d10 is the deuterium labeled 1,5-Dibromopentane [1].
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- HY-128792S
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1,3-Dipalmitin-d6 (1,3-Dipalmitoylglycerol-d6) is deuterium labeled 1,3-Dipalmitin (HY-128792). 1,3-Dipalmitin (1,3-Dipalmitoylglycerol) is a diacylglycerol compound that can be found in the tuberous roots of Typhonium giganteum Engl. 1,3-Dipalmitin acts as an adsorption inhibitor for 1,3-diglycerides and β-carotene [1] .
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- HY-W040193S1
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DSPC-d74 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system [1] .
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- HY-Y1044S
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1,5-Dihydroxypentane-d10 is the deuterium labeled 1,5-Dihydroxypentane [1].
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- HY-Y0093S
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NSC 5416-d14 is the deuterium labeled NSC 5416 [1].
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- HY-W040193S
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DSPC-d70 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system [1] .
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- HY-W040193S6
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DSPC-d13 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d13) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system [1] .
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- HY-W040193S2
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DSPC-d79 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d79) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system [1] .
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- HY-W749377
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1,2,3,4,5-Pentabromo-6-methylbenzene- 13C6 (Toluene, 2,3,4,5,6-pentabromo- 13C6) is the 13C-labeled 1,2,3,4,5-Pentabromo-6-methylbenzene (HY-W274110).
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- HY-W699983
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Imidazole- 15N2 (Glyoxaline- 15N2) is 15N labeled Imidazole. Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG2 and PGH2) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CL Pro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease [1] .
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- HY-W040193S3
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DSPC-d83 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d83) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system [1] .
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- HY-113123S1
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LysoPC(14:0/0:0)-d7 (14:0 Lyso PC-d7) is deuterium labeled LysoPC(14:0/0:0). LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect [1] .
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- HY-146894S
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1-Stearoyl-2-stearoyl-sn-glycero-3-phosphocholine-d35 is deuterium labeled 1-Stearoyl-2-stearoyl-sn-glycero-3-phosphocholine.
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- HY-W040193S5
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DSPC-d9 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d9) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system [1] .
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- HY-Y1772S
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1-Iodo-4-methylbenzene-d7 is the deuterium labeled 1-Iodo-4-methylbenzene [1].
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- HY-W285163S
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1-Cyclopropyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid-d8 is deuterated labeled 1-Cyclopropyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid.
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- HY-134178S1
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5-F-UTP- 13C, 19F,d1 is deuterium and 13C-labeled 5-F-UTP (HY-134178).
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- HY-12650S
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Mirogabalin- 13C2,d1 (Mixture of Diastereomers) is a 13C and deuterium labeled Mirogabalin. Mirogabalin (DS-5565) is a preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS [1].
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- HY-W040193S4
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DSPC-d4 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d4) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system [1] .
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- HY-Y0860S
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1,6-Dibromo-n-hexane-d12 is the deuterium labeled 1,6-Dibromo-n-hexane [1].
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- HY-146881S
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1-Myristoyl-2-myristoyl-sn-glycero-3-phosphocholine-d27 is deuterium labeled 1-Myristoyl-2-myristoyl-sn-glycero-3-phosphocholine.
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- HY-122056S1
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1,2-Diheptanoyl-SN-glycero-3-phosphocholine-d26 (L-α-Diheptanoyllecithin-d26) is the deuterium labeled 1,2-Diheptanoyl-SN-glycero-3-phosphocholine (HY-122056). 1,2-Diheptanoyl-SN-glycero-3-phosphocholine (L-α-Diheptanoyllecithin; 12-Diheptanoyl-sn-glycero-3-PC) is an ester product.
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- HY-W583868S
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1-Palmitoyl-2-oleoyl-sn-glycero-3-PE-d62 (1,2-POPE-d62) is the deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE (1,2-POPE; 16:0-18:1 PE) is a phosphatidylethanolamine (PE) lipid. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can induce lipid bilayer to form a hexagonal phase (HII) structure in an acidic environment and promote membrane fusion. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can enhance the endosomal escape ability of lipid nanoparticles (LNPs) and improve the cellular delivery efficiency of nucleic acid drugs such as mRNA. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can be used for LNP carrier targeting of gene therapy and mRNA vaccines [1] .
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- HY-178703S
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1,2-Diheptanoyl-SN-glycero-3-phosphocholine-d9 (L-α-Diheptanoyllecithin-d9) is the deuterium labeled 1,2-Diheptanoyl-SN-glycero-3-phosphocholine.
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- HY-Y0659S
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1,2,3,4-Hydroquinoline-d2 (1,2,3,4-Tetrahydroquinoline-d2) is the deuterium labeled 1,2,3,4-Hydroquinoline.
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- HY-122056S
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1,2-Diheptanoyl-SN-glycero-3-phosphocholine-d35 (L-α-Diheptanoyllecithin-d35) is the deuterium labeled 1,2-Diheptanoyl-SN-glycero-3-phosphocholine (HY-122056). 1,2-Diheptanoyl-SN-glycero-3-phosphocholine (L-α-Diheptanoyllecithin; 12-Diheptanoyl-sn-glycero-3-PC) is an ester product.
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- HY-W013053S
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Dibenz[a,h]anthracene-d14 is the deuterium Dibenz[a,h]anthracene.
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- HY-W762019S
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1,2,3,4,7,8-Hexachloro dibenzo-p-dioxin- 13C12 (1,2,3,4,7,8-HxCDD- 13C12) is 13C labeled 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin [1].
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- HY-W662572S
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Pyroxsulam-d6 (N-(5,7-Dimethoxy-d6[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide) is deuterium labeled N-(5,7-Dimethoxy-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide [1].
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- HY-41681S
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6-Chloro-1-hexanol-d6 is the deuterium labeled 6-Chloro-1-hexanol [1].
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- HY-W050145S2
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Levoglucosan- 13C6 is the 13C labeled Levoglucosan [1]. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature .
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- HY-151997S
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1,2-Dioleoyl-3-lauroyl-rac-glycerol- 13C3 is the 13C-labeled 1,2-Dioleoyl-3-lauroyl-rac-glycerol (HY-165089), 1,2-Dioleoyl-3-lauroyl-rac-glycerol (1,2-Olein-3-laurin) is a triglyceride identified by specific analytical methods in human milk, infant formula, other mammalian milk, and vegetable oils, with specific structural and distribution characteristics.
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- HY-141919S
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1-Bromo-4-iodobenzene- 13C6 is the 13C labeled 1-Bromo-4-iodobenzene [1].
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- HY-115705S
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1,2,3-Tri-10(Z)-Heptadecenoyl Glycerol-d5 is the deuterium labeled 1,2,3-Tri-10(Z)-Heptadecenoyl Glycerol [1].
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- HY-W766078
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1-beta-D-Arabinofuranosyluracil- 13C, 15N2 (1-b-D-Arabinofuranosyluracil- 13C, 15N2; Uracil 1-β-D-arabinofuranoside- 13C, 15N2) is the 13C- and 15N-labeled labeled 1-beta-D-Arabinofuranosyluracil (HY-N6652). 1-beta-D-Arabinofuranosyluracil (Uracil 1-β-D-arabinofuranoside) isolated from the Caribbean sponge Tectitethya crypta, is a methoxyadenosine derivative. 1-beta-D-Arabinofuranosyluracil has demonstrated a diverse bioactivity profile including anti-inflammatory activity, analgesic and vasodilation properties [1]. 1-beta-D-Arabinofuranosyluracil reduces a proliferation of mouse lymphoma cells .
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- HY-Y0219S
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NSC 83128- 13C2, 15N3 is the 13C and 15N labeled NSC 83128 [1].
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- HY-A0052S
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(1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1R)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide-d4 is deuterated labeled (1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1R)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide.
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- HY-Y0045S
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2-Acetylthiazole- 13C2 is 13C labeled 2-Acetylthiazole (HY-Y0045). 2-Acetylthiazole (1-(1,3-Thiazol-2-yl)ethanone; 1-(Thiazol-2-yl)ethanone; Methyl 2-thiazolyl ketone) is a flavor compound. 2-Acetylthiazole is a kind of biological materials or organic compounds that are widely used in life science research [1].
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- HY-33948S
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1-Amino-2-methylpropan-2-ol-d6 is the deuterium labeled 1-Amino-2-methylpropan-2-ol [1].
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- HY-59354S1
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1,2-Dihydropyridazine-3,6-dione-3,4,5,6- 13C4 (1,2-Dihydro-3,6-pyridazine- 13C4-dione) is 13C labeled Maleic hydrazide. Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins [1] .
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- HY-34123S
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N-(2-Bromoethyl)phthalimide-d4 is the deuterium labeled N-(2-Bromoethyl)phthalimide[1].
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- HY-W778954
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2,2-Dimethyl-1,3-dioxolane-4-methanol- 13C3 ((2,2-Dimethyl-[1,3] dioxane-4-yl)-methanol- 13C3) is the 13C-labeled 2,2-Dimethyl-1,3-dioxolane-4-methanol (HY-Y1372).
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Classification |
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- HY-RS13999
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siRNAs
Human Pre-designed siRNA Sets
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SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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- HY-RS18793
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siRNAs
Mouse Pre-designed siRNA Sets
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Sub1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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- HY-RS25282
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siRNAs
Rat Pre-designed siRNA Sets
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Sub1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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- HY-125783S
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16:0 Lyso PC-d<SUB>9SUB>
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Phospholipids
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1-Palmitoyl-sn-glycero-3-phosphocholine-d9 (16:0 Lyso PC-d9) is deuterium labeled 1-Palmitoyl-sn-glycero-3-phosphocholine (HY-125783). 1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis [1] .
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![(1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1R)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide-d4](http://file.medchemexpress.com/product_pic/hy-a0052s.gif)
