Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
SYVN1
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "SYVN1" in MCE Product Catalog:
7
7 Cited Publications
Cat. No.: HY-135844
CAS No.: 1456891-34-1
Target:
Research Areas:
LS-102 is a selective E3 ubiquitin ligase synoviolin (Syvn1) inhibitor. LS-102 inhibits the autoubiquitination of synoviolin with an IC50 of 35 μM. LS-102 has the potential for rheumatoid arthritis treatment [1] .
Cat. No.: HY-RS18845
Target:
Research Areas:
Syvn1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Syvn1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14127
Target:
Research Areas:
SYVN1 Human Pre-designed siRNA Set A contains three designed siRNAs for SYVN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25337
Target:
Research Areas:
Syvn1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Syvn1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-184455
Target:
Research Areas:
PROTAC BRD4 Degrader-47 is a heterobifunctional PROTAC that selectively degrades BRD4 in a SYVN1-dependent manner, with a DC50 of 0.93 μM. PROTAC BRD4 Degrader-47 can be used in cancer-related research such as breast cancer [1].
Cat. No.: HY-184457
CAS No.: 2441860-09-7
Target:
Research Areas:
NH2-C-Ph-hexyne-C4-NH2 is a PROTAC linker. NH2-C-Ph-hexyne-C4-NH2 can connect the BRD4 ligand JQ1 (HY-13030) with the SYVN1 ligand Clofibric acid (HY-B1415), thereby achieving the degradation of BRD4 via the PROTAC mechanism. NH2-C-Ph-hexyne-C4-NH2 can be used for the synthesis of PROTAC BRD4 Degrader-47 (HY-184455) [1].
Cat. No.: HY-P87091
Synonyms: 1200010C09Rik antibody; DER3 antibody; E3 ubiquitin-protein ligase synoviolin antibody; HMG coA reductase degradation 1 homolog antibody; HRD1 antibody; KIAA1810 antibody; MGC40372 antibody; OTTHUMP00000230429 antibody; OTTHUMP00000230430 antibody; OTTHUMP00000230431 antibody; 1200010C09Rik antibody; DER3 antibody; E3 ubiquitin-protein ligase synoviolin antibody; HMG coA reductase degradation 1 homolog antibody; HRD1 antibody; KIAA1810 antibody; MGC40372 antibody; OTTHUMP00000230429 antibody; OTTHUMP00000230430 antibody; OTTHUMP00000230431 antibody; OTTHUMP00000230432 antibody; Synovial apoptosis inhibitor 1 antibody; Synovial apoptosis inhibitor 1, synoviolin antibody; Synoviolin 1 antibody; Synoviolin 1 isoform b antibody; SYNOVIOLIN antibody; SYVN1 antibody; SYVN1_HUMAN antibody;
Cat. No.: HY-184456
Research Areas:
Clofibric acid-C-Ph-hexyne-C4-NH2 is an E3 Ligase Ligand-Linker Conjugate that can be used in studies related to PROTAC synthesis, such as for PROTAC BRD4 Degrader-47 (HY-184455) [1].
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
