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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
45 Results for "
Sialyltransferase
" in MedChemExpress (MCE) Product Catalog:
Products (45)
45 Results for "Sialyltransferase" in MCE Product Catalog:
5
5 Cited Publications
Target:
Research Areas:
3FAx-Neu5Ac (Compound 8), a Sialic acid peracetylated analog, is a sialyltransferase inhibitor. 3FAx-Neu5Ac substantially reduces expression of the sialylated ligand sialyl Lewis X .
3
3 Cited Publications
Synonyms: CMP-Neu5Ac sodium salt
Target:
1
Target:
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alpha-2,8-Sialyltransferase (CstII) (ST8Sia VI) is a member of alpha2,8-sialyltransferase (ST8Sia) family, is often used in biochemical studies. alpha-2,8-Sialyltransferase (CstII) catalyzes elongation of the α2,8-linked oligo/polysialic acid chain on the Sia residue transferred .
1
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CMP-SiaNAz (CMP-NeuNAz) sodium is a sialic acid nucleotide sugar derivative. CMP-SiaNAz sodium is integrated into the glycosidic chain through the action of STs in the Golgi apparatus, forming SiaNAz substances. CMP-SiaNAz sodium can serve as a substrate for bacterial-derived sialic acid transferases and is used for chemical enzymatic labeling and imaging of cell surface glycosides .
1
1 Cited Publications
Cat. No.: HY-P76094
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ST6GAL1; ST6GalI; Prev. SIAT1; Sialyltransferase 1 (Beta-Galactoside Alpha-2,6-Sialyltransferase); Beta-Galactoside Alpha-2,6-Sialyltransferase 1; Sialyltransferase 1 (Beta-Galactoside Alpha-2,6-Sialytransferase); CDw75; Beta-Galactoside Alpha-(2,6)-Sialy
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Research Areas:
alpha-2,6-Sialyltransferase (Pd26ST) (EC 2.4.99.1) is capable of sialylating both terminal and internal galactose and N-acetylgalactosamine, which producing terminal α2,6-sialosides .
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Research Areas:
CMP-sialic acid synthetase (NmCSS) is an essential enzyme involved in the biosynthesis of carbohydrates and glycoconjugates containing sialic acids. CMP-sialic acid synthetase (NmCSS) activates free Sia, converting it to CMP-Sia, which is the only donor substrate for all sialyltransferases .
Cat. No.: HY-E70056
CAS No.: 71124-51-1
Synonyms: PmST1(M144D)
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α2,3-Sialyltransferase, Pasteurella multocida (P-1059) (PmST1(M144D)), a sialyltransferase, can be isolated from Pasteurella multocida. alpha-2,3-Sialyltransferase (PmST1) can be converted into regioselective α2-6-sialyltransferase by saturation mutagenesis and regioselective screening .
Category:
Human Gut Microbiota Metabolites Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-173496
CAS No.: 192876-13-4
Target:
Research Areas:
ST6GAL1-IN-1 is an orally active selective ST6GAL1 inhibitor (IC50 = 20 μM). ST6GAL1-IN-1 exhibits high antimetastatic potential, effectively inhibiting the migration of MDA-MB-231 cells at noncytotoxic concentrations. ST6GAL1-IN-1 can disrupt integrin sialylation in MDA-MB-231 cells. ST6GAL1-IN-1 inhibits tumor angiogenesis and cancer metastasis via the Integrin/VEGFR2-mediated signaling pathway. ST6GAL1-IN-1 effectively suppresses both tumor growth and cancer metastasis on the MDA-MB-231 xenograft model. ST6GAL1-IN-1 can be used for the study of Triple-negative breast cancer (TNBC) .
Cat. No.: HY-E70065
CAS No.: 71124-51-1
Target:
alpha-2,3-Sialyltransferase (PmST2) is a monofunctional α2-3 sialyltransferase that belongs to the GT52 family of Carbohydrate-Active enZymes (CAZy). alpha-2,3-Sialyltransferase (PmST2) catalyzes the transfer of sialic acid from CMP-Neu5Ac to the C3 position of galactose in lactosyl lipids, β1-4 linked galactosyl disaccharide lipids, and β-galactosyl monosaccharide lipids, with its catalytic activity decreasing sequentially toward these substrate classes. The function ofalpha-2,3-Sialyltransferase (PmST2) is independent of divalent metal cations and disulfide bonds, and it retains α2-3 sialyltransferase activity over a pH range of 4.5-10.0, with optimal activity observed at pH 6.0 .
Synonyms: α-2,3-Sialyltransferase-IN-1
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Research Areas:
(R)-Lith-O-Asp (α-2,3-Sialyltransferase-IN-1) is a noncompetitive α-2,3-sialyltransferase inhibitor with an IC50 of 6 μM.
Cat. No.: HY-E70063
CAS No.: 71124-51-1
Target:
Research Areas:
alpha-2,3-Sialyltransferase (Phα2,3SiaT) is a beta-galactoside. alpha-2,3-Sialyltransferase (Phα2,3SiaT) catalyzes the transfer of sialic acid to carbohydrate groups of glycoproteins and glycolipids .
Cat. No.: HY-E70062
CAS No.: 71124-51-1
Synonyms: Fh8-PmST3
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Research Areas:
alpha-2,3-Sialyltransferase (PmST3) (EC 2.4.99.4) is a beta-galactoside. alpha-2,3-Sialyltransferase (PmST3) catalyzes the transfer of sialic acid to carbohydrate groups of glycoproteins and glycolipids .
Cat. No.: HY-E70150
Synonyms: EC:2.4.3.3; Alpha-N-Acetylgalactosaminide alpha-2,6-Sialyltransferase 1
Cat. No.: HY-E70287
Synonyms: ST6GALNAC5
Target:
Research Areas:
ST6 Sialyltransferase 5 (EC:2.4.3.3, ST6GALNAC5, SIAT7E, ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5) transfers a sialic acid to N-acetylgalactosamine (GalNAc) residues. ST6 Sialyltransferase 5 is a bio-marker in cervical screening samples .
Cat. No.: HY-E70152
Synonyms: EC:2.4.3.7; ST6GALNAC4; SIAT3-C
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
