2. Metabolic Enzyme/Protease
  3. Sialyltransferase
  4. 3FAx-Neu5Ac

3FAx-Neu5Ac (compound 8), a Sialic acid peracetylated analog, is a sialyltransferase inhibitor. 3FAx-Neu5Ac substantially reduces expression of the sialylated ligand sialyl Lewis X on myeloid cells.

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3FAx-Neu5Ac Chemical Structure

3FAx-Neu5Ac Chemical Structure

CAS No. : 117405-58-0

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1 mg USD 160 In-stock
5 mg USD 320 In-stock
10 mg USD 528 In-stock
25 mg USD 1135 In-stock
50 mg USD 1920 In-stock
100 mg USD 3150 In-stock
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Based on 1 publication(s) in Google Scholar

3FAx-Neu5Ac Related Antibodies

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Description

3FAx-Neu5Ac (compound 8), a Sialic acid peracetylated analog, is a sialyltransferase inhibitor. 3FAx-Neu5Ac substantially reduces expression of the sialylated ligand sialyl Lewis X on myeloid cells[1].

Molecular Weight

551.47

Formula

C22H30FNO14
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

COC([C@]1(O[C@@]([C@H](NC(C)=O)[C@@H](OC(C)=O)[C@H]1F)([H])[C@H](OC(C)=O)[C@H](OC(C)=O)COC(C)=O)OC(C)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (181.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8133 mL 9.0667 mL 18.1334 mL
5 mM 0.3627 mL 1.8133 mL 3.6267 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (258 KB) Elemental Analysis Report (116 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8133 mL 9.0667 mL 18.1334 mL 45.3334 mL
5 mM 0.3627 mL 1.8133 mL 3.6267 mL 9.0667 mL
10 mM 0.1813 mL 0.9067 mL 1.8133 mL 4.5333 mL
15 mM 0.1209 mL 0.6044 mL 1.2089 mL 3.0222 mL
20 mM 0.0907 mL 0.4533 mL 0.9067 mL 2.2667 mL
25 mM 0.0725 mL 0.3627 mL 0.7253 mL 1.8133 mL
30 mM 0.0604 mL 0.3022 mL 0.6044 mL 1.5111 mL
40 mM 0.0453 mL 0.2267 mL 0.4533 mL 1.1333 mL
50 mM 0.0363 mL 0.1813 mL 0.3627 mL 0.9067 mL
60 mM 0.0302 mL 0.1511 mL 0.3022 mL 0.7556 mL
80 mM 0.0227 mL 0.1133 mL 0.2267 mL 0.5667 mL
100 mM 0.0181 mL 0.0907 mL 0.1813 mL 0.4533 mL
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3FAx-Neu5Ac Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3FAx-Neu5Ac117405-58-0SialyltransferaseSialic acid peracetylated analogsialyltransferase inhibitorLewis XInhibitorinhibitorinhibit

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