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Cat. No.: HY-110288R

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3FAx-Neu5Ac (Standard)

3FAx-Neu5Ac (Standard) is the analytical standard of 3FAx-Neu5Ac (HY-110288). This product is intended for research and analytical applications. 3FAx-Neu5Ac (Compound 8), a Sialic acid peracetylated analog, is a sialyltransferase inhibitor. 3FAx-Neu5Ac substantially reduces expression of the sialylated ligand sialyl Lewis X.

For research use only. We do not sell to patients.

CAS No.: 117405-58-0
Formula: C₂₂H₃₀FNO₁₄
Molecular Weight:551.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

3FAx-Neu5Ac (Standard) Chemical Structure

CAS No.: 117405-58-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 117405-58-0
Molecular Weight 551.47
Formula C₂₂H₃₀FNO₁₄
SMILES

COC([C@]1(O[C@@]([C@H](NC(C)=O)[C@@H](OC(C)=O)[C@H]1F)([H])[C@H](OC(C)=O)[C@H](OC(C)=O)COC(C)=O)OC(C)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Cory D Rillahan, et al. Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome. Nat Chem Biol. 2012 Jul;8(7):661-8. [Content Brief]

[2]. Natoni A, et al. Inhibition of Sialylation Impairs Adhesion on Madcam-1 and E-Selectin and Sensitize Multiple Myeloma Cells to Bortezomib in a Xenograft Mouse Model. Blood, 2018, 132: 3204.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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