6 Results for "

Stephania plants

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Stephania plants" in MCE Product Catalog:

14
Cepharanthine
Cepharanthine
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14 Cited Publications
Cat. No.: HY-N6972
CAS No.: 481-49-2
Category:  

Infection Alkaloids Stephania cepharantha Hayata Plants Disease Research Fields Isoquinoline Alkaloids Inflammation/Immunology Menispermaceae Stephania japonica (Thunb.) Miers

Target:  

Autophagy SARS-CoV Cytochrome P450 Apoptosis Parasite

Cepharanthine is a natural product that can be isolated from the plant Stephania cephalantha Hayata. Cepharanthine has anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) activities. Cepharanthine has good effective in suppressing viral proliferation (half maximal (50%) inhibitory concentration (IC50) and 90% inhibitory concentration (IC90) values of 1.90 and 4.46 μM . Cepharanthine can also effectively reverses P-gp-mediated multidrug resistance in K562 cells and increase enhances the sensitivity of anticancer agents in xenograft mice model . Cepharanthine shows inhibitory effects of human liver cytochrome P450 enzymes CYP3A4, CYP2E1 and CYP2C9. Cepharanthine has antitumor, anti-inflammatory and antinociceptive effects .
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Dicentrine
Dicentrine
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Cat. No.: HY-N6969
CAS No.: 517-66-8
Category:  

Alkaloids Stephania epigaea Lo Plants Disease Research Fields Isoquinoline Alkaloids Menispermaceae Endocrinology

Target:  

Adrenergic Receptor

Dicentrine is a natural product isolated from the plant Stephania epigaea Lo with antihypertensive effect. Dicentrine is an α1-adrenoceptor antagonist which has effective against human hyperplastic prostates .
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Cepharanthine (Standard)
Cepharanthine (Standard)
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Cat. No.: HY-N6972R
CAS No.: 481-49-2
Category:  

Alkaloids Stephania cepharantha Hayata Plants Isoquinoline Alkaloids Menispermaceae Stephania japonica (Thunb.) Miers

Target:  

Autophagy Reference Standards SARS-CoV Cytochrome P450 Apoptosis Parasite

Cepharanthine (Standard) is the analytical standard of Cepharanthine. This product is intended for research and analytical applications. Cepharanthine is a natural product that can be isolated from the plant Stephania?cephalantha?Hayata. Cepharanthine has anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) activities. Cepharanthine has good effective in suppressing viral proliferation (half maximal (50%) inhibitory concentration (IC50) and 90% inhibitory concentration (IC90) values of 1.90 and 4.46?μM . Cepharanthine can also effectively reverses P-gp-mediated multidrug resistance in K562 cells and increase enhances the sensitivity of anticancer agents in xenograft mice model . Cepharanthine shows inhibitory effects of human liver cytochrome P450 enzymes CYP3A4, CYP2E1 and CYP2C9. Cepharanthine has antitumor, anti-inflammatory and antinociceptive effects .
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Isolaureline
Isolaureline
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Cat. No.: HY-N11914
CAS No.: 475-84-3
Category:  

Plants Stephania longa Lour. Menispermaceae

Target:  

Others

Isolaureline can be isolated from the whole plant of Stephania longa .
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Homostephanoline
Homostephanoline
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Cat. No.: HY-N18876
CAS No.: 2689-15-8
Category:  

Alkaloids Aporphine Alkaloids Plants Menispermaceae Stephania japonica (Thunb.) Miers

Target:  

Drug Derivative

Homostephanoline is a corydane-type alkaloid that can be isolated from species of the Stephania subgenus .
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Stephalonine P
Stephalonine P
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Cat. No.: HY-N13729
CAS No.: 2376309-57-6
Category:  

Alkaloids Other Alkaloids Plants Menispermaceae Stephania japonica (Thunb.) Miers

Target:  

NO Synthase

Stephalonine P is a hasubanan-type alkaloid anti-inflammatory agent with neuroprotective effects against neuroinflammation. Stephalonine P regulates post-ischemic inflammatory responses by inhibiting NO production in LPS-activated BV2 microglia (IC50=34.01 μM), thereby reducing microglial activation and neuronal damage. Stephalonine P can be isolated from the whole plant of Stephania japonica. Stephalonine P can be used in research on stroke and other neuroinflammation-related diseases .
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