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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
UBE2N
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "UBE2N" in MCE Product Catalog:
8
8 Cited Publications
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NSC697923 is a potent UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13) inhibitor. NSC697923 induces neuroblastoma (NB) cell death via promoting nuclear importation of p53 in p53 wild-type NB cells. NSC697923 also induces cell death in p53 mutant NB cells by activation of JNK-mediated apoptotic pathway. NSC697923 inhibits DNA damage and NF-κB signaling. Antitumor activity [2].
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UC-764864 is a selective UBE2N inhibitor. UC-764864 covalently binds UBE2N catalytic Cys87, blocks ubiquitin-UBE2N thioester formation and polyubiquitin chain synthesis. UC-764864 blocks ubiquitination of innate immune- and inflammatory-related substrates, and induces cell apoptosis. UC-764864 can be used for the research of acute myeloid leukemia .
Cat. No.: HY-RS15356
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UBE2N Human Pre-designed siRNA Set A contains three designed siRNAs for UBE2N gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24781
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Ube2n Rat Pre-designed siRNA Set A contains three designed siRNAs for Ube2n gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18303
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Ube2n Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ube2n gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P79452
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Ubiquitin-conjugating enzyme E2 N; UbcH13
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Cat. No.: HY-P704079
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Ubiquitin-conjugating enzyme E2 N; UbcH13
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
