10 Results for "

VSIG3

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "VSIG3" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P991447

Target:  

VISTA

Research Areas:  

Cancer

Anti-VSIR/VISTA Antibody (SG7) is an antibody targeting VISTA, with a Kd of 0.14 nM for human VISTA and 1 nM for mouse VISTA. Anti-VSIR/VISTA Antibody (SG7) blocks the function of VISTA, prevents VISTA from binding to T cells, restores suppressed T cell activation, and blocks the interactions between VISTA and PSGL-1 as well as VSIG3. Anti-VSIR/VISTA Antibody (SG7) slows tumor growth, reduces PMN-MDSCs, and increases the numbers of CD4 + and CD8 + T cells in the tumor microenvironment. Anti-VSIR/VISTA Antibody (SG7) can be used in studies related to melanoma, colon cancer, and breast cancer .
loading...
    loading...
Cat. No.: HY-P990145

Target:  

VISTA

Research Areas:  

Inflammation/Immunology Cancer

Anti-Mouse VISTA Antibody (13F3) is an anti-mouse VISTA IgG monoclonal antibody. Anti-Mouse VISTA Antibody (13F3) can reverse the immunosuppressive effect of VISTA by blocking its binding to ligands such as VSIG3. Anti-Mouse VISTA Antibody (13F3) exacerbates pulmonary fibrosis (PF) by promoting Th17 cell differentiation. Anti-Mouse VISTA Antibody (13F3) can be used for research on cancer such as breast cancer and PF .
loading...
    loading...
Cat. No.: HY-P992369

Target:  

VISTA

Research Areas:  

Cancer

HMBD-002 is an Fc-independent, non-depleting IgG4 subclass antibody that targets VISTA and VSIG3. It is widely used in research related to various solid tumors, including colon cancer, triple-negative breast cancer, and non-small cell lung cancer. HMBD-002 blocks the interactions of VISTA with VSIG3 and LRIG1, relieves immunosuppression without depleting VISTA-positive cells, activates the cytotoxic program of CD8 + T cells, and drives the type I interferon signaling pathway. HMBD-002 reprograms tumor-associated macrophages to the M1 phenotype, reduces tumor infiltration of inhibitory myeloid cells, thereby significantly inhibiting tumor growth and improving survival. HMBD-002 is well tolerated in rodent and non-human primate animal models [3] .
loading...
    loading...
Cat. No.: HY-P89018
Synonyms: BT-IgSF; CT119; CXADRL1; Igsf13; VSIG3

Host:  

Mouse

Application:  

IHC-P

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
Cat. No.: HY-P89018A
Synonyms: BT-IgSF; CT119; CXADRL1; Igsf13; VSIG3

Host:  

Mouse

Application:  

IHC-P

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
Cat. No.: HY-P70854
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGSF11; CXADRL1; Immunoglobulin Superfamily Member 11; BTIGSF; VSIG3; Brain And Testis-Specific Immunoglobin Superfamily Protein; BT-IgSF; V-Set And Immunoglobulin Domain Containing 3; Igsf13; Immunoglobulin Superfamily, Member 11; CT119; Alternative Prot
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-RS06647
Research Areas:  

Others

IGSF11 Human Pre-designed siRNA Set A contains three designed siRNAs for IGSF11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-P76411
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IGSF11; CXADRL1; Immunoglobulin Superfamily Member 11; BTIGSF; VSIG3; Brain And Testis-Specific Immunoglobin Superfamily Protein; BT-IgSF; V-Set And Immunoglobulin Domain Containing 3; Igsf13; Immunoglobulin Superfamily, Member 11; CT119; Alternative Prot
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P78788
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGSF11; CXADRL1; Immunoglobulin Superfamily Member 11; BTIGSF; VSIG3; Brain And Testis-Specific Immunoglobin Superfamily Protein; BT-IgSF; V-Set And Immunoglobulin Domain Containing 3; Igsf13; Immunoglobulin Superfamily, Member 11; CT119; Alternative Prot
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P700738
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGSF11; CXADRL1; Immunoglobulin Superfamily Member 11; BTIGSF; VSIG3; Brain And Testis-Specific Immunoglobin Superfamily Protein; BT-IgSF; V-Set And Immunoglobulin Domain Containing 3; Igsf13; Immunoglobulin Superfamily, Member 11; CT119; Alternative Prot
Species:  
Source:  
loading...
    loading...