2. Recombinant Proteins
  3. Receptor Proteins
  4. Cell Adhesion Molecules (CAMs)
  5. Immunoglobulin-like Cell Adhesion Molecules
  6. Immunoglobulin Superfamily Member 11 (IGSF11)
  7. IGSF11 Protein, Human (HEK293, His)

IGSF11 Protein, Human (HEK293, His)

Cat. No.: HY-P76411
Handling Instructions

Immunoglobulin superfamily member 11 was originally identified as a member of the immunoglobulin superfamily, and it has been revealed to function as a CAM in a calciumindependent manner. Immunoglobulin superfamily member 11, a homophilic adhesion molecule that preferentially expressed in the brain, is a dual-binding partner of the postsynaptic scaffolding protein PSD-95 and AMPA glutamate receptors (AMPARs). IGSF11 Protein, Human (HEK293, His) is the recombinant human-derived IGSF11 protein, expressed by HEK293 , with C-His labeled tag. The total length of IGSF11 Protein, Human (HEK293, His) is 218 a.a., with molecular weight of ~36 KDa.

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Description

Immunoglobulin superfamily member 11 was originally identified as a member of the immunoglobulin superfamily, and it has been revealed to function as a CAM in a calciumindependent manner. Immunoglobulin superfamily member 11, a homophilic adhesion molecule that preferentially expressed in the brain, is a dual-binding partner of the postsynaptic scaffolding protein PSD-95 and AMPA glutamate receptors (AMPARs). IGSF11 Protein, Human (HEK293, His) is the recombinant human-derived IGSF11 protein, expressed by HEK293 , with C-His labeled tag. The total length of IGSF11 Protein, Human (HEK293, His) is 218 a.a., with molecular weight of ~36 KDa.
Background

Immunoglobulin superfamily member 11 is an immunoglobulin superfamily member that is preferentially expressed in brain and testis. Immunoglobulin superfamily member 11 shares significant homology with coxsackievirus and adenovirus receptor and endothelial cell-selective adhesion molecule. Immunoglobulin superfamily member 11 enables ionotropic glutamate receptor binding and is involved in homophilic cell adhesion via plasma membrane adhesion molecules[1][2][3][4].
Species

Human
Source

HEK293
Tag

C-His
Accession

AAH34411.1 (E23-G240)
Gene ID
Molecular Construction
N-term
IGSF11 (E23-G240)
Accession # AAH34411.1
His
C-term
Synonyms
BT-IgSF; CT119; CXADRL1; Igsf13; VSIG3
Molecular Weight

Approximately 36 kDa.
Purity

Greater than 85% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

IGSF11 Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

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Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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