1 Result for "

VU0240551

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "VU0240551" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-16689
CAS No.: 893990-34-6
Target:  

Potassium Channel

Research Areas:  

Others

VU 0240551 is a potent neuronal K-Cl cotransporter KCC2 inhibitor (IC50=560 nM) and is selective versus NKCC1. VU 0240551 also inhibits hERG and L-type Ca 2+ channels. VU 0240551 attenuates GABA-induced hyperpolarization of P cells, produces a positive shift in the P cell GABA reversal potential and enhances P cell synaptic transmission .
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