5 Results for "

acute enteritis

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "acute enteritis" in MCE Product Catalog:

Cat. No.: HY-A0248B
CAS No.: 34503-87-2
Target:  

Antibiotic Bacterial

Research Areas:  

Infection Inflammation/Immunology

Polymyxin B2 is a polypeptide antibiotic with particularly potent antibacterial activity against Gram-negative bacteria. Polymyxin B2 kills bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting membrane integrity and causing leakage of intracellular contents. Polymyxin B2 is used in studies related to Pseudomonas aeruginosa infection and acute enteritis .
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Cat. No.: HY-A0248C
CAS No.: 108965-69-1
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Polymyxin B2 Sulfate is a polypeptide antibiotic with particularly potent antibacterial activity against Gram-negative bacteria. Polymyxin B2 Sulfate kills bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting membrane integrity and causing leakage of intracellular contents. Polymyxin B2 Sulfate is used in studies related to Pseudomonas aeruginosa infection and acute enteritis .
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Cat. No.: HY-176554
CAS No.: 3084814-46-7
sEH-IN-21 is an orally active sEH inhibitor with IC50s of 0.1 nM for hsEH and msEH. sEH-IN-21 potently inhibits NF-κB signaling pathways. sEH-IN-21 shows a strong anti-inflammatory activity, decreases the release of IL-6 and TNF-α and maintained the integrity of the intestinal barrier. sEH-IN-21 can be used for the study of inflammatory bowel disease (IBD) .
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Cat. No.: HY-163466
CAS No.: 3036752-72-1
Target:  

FXR

Research Areas:  

Inflammation/Immunology

FXR agonist 7 (compound 33) is a potent agonist of FXR, with EC50 of 0.1 nM. FXR agonist 7 shows high intestinal distribution, good anti-inflammatory activity .
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Cat. No.: HY-P10914
CAS No.: 1426227-11-3
Target:  

MDM-2/p53 Autophagy

Research Areas:  

Inflammation/Immunology Cancer

D-CopA3 is the inhibitor for MDM2 and the activator for p53 signaling pathway. D-CopA3 exhibits cytotoxicity in colorectal cancer cells HCT-116, LoVo, and RKO (IC50=15-18 μM), induces JNK/Beclin-1 mediated autophagy. D-CopA3 downregulates the expression of cell cycle inhibitory protein p21Cip1/Waf1, enhances the mucosal barrier function and reduces penetration of inflammatory mediators. D-CopA3 exhibits anti-inflammtory activity in mouse C. difficile toxin A-induced acute enteritis models and DSS (HY-116282)-induced chronic colitis models. D-CopA3 exhibits antitumor efficacy in mouse HCT-116 xenograft models .
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